The Prognostic Landscape of Tumor-Infiltrating Immune Cells and Immune Checkpoints in Glioblastoma.

abstract：:The objective of this study is to compare the new and conventional tomotherapy treatment techniques and to evaluate dosimetric differences between them. A dosimetric analysis was performed by comparing planning target volume (PTV) median dose, 95% of PTV dose coverage, Paddick conformity index (CI), homogeneity index ...

journal_title：Technology in cancer research & treatment

authors： Zhang X,Penagaricano J,Han EY,Morrill S,Hardee M,Liang X,Gupta SK,Corry PM,Ratanatharathom V

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To investigate the role of intensity-modulated proton therapy (IMPT) for hepatocellular carcinoma (HCC) patients to be treated with stereotactic body radiation therapy (SBRT) in a risk-adapted dose prescription regimen. METHODS:A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escala...

journal_title：Technology in cancer research & treatment

authors： Cozzi L,Comito T,Loi M,Fogliata A,Franzese C,Franceschini D,Clerici E,Reggiori G,Tomatis S,Scorsetti M

更新日期：2020-01-01 00:00:00

abstract：:A 51 year old male with a history of right facial numbness developed progressive upper lip swelling for one year, but an MRI of the head was unremarkable. A wide local excision of the upper lip was performed and pathology revealed a 1.7 cm mass, poorly differentiated squamous cell carcinoma with perineural invasion. S...

journal_title：Technology in cancer research & treatment

authors： Bhatnagar AK,Heron DE,Schaitkin B

更新日期：2005-06-01 00:00:00

abstract：:The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C(60)(OH)(24) in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Experiment was performed on adult female Spra...

journal_title：Technology in cancer research & treatment

authors： Injac R,Perse M,Boskovic M,Djordjevic-Milic V,Djordjevic A,Hvala A,Cerar A,Strukelj B

更新日期：2008-02-01 00:00:00

abstract：:Brachytherapy has the advantage of delivering a high dose to the tumor while sparing the surrounding normal tissues. With proper case selection and delivery technique, high-dose-rate (HDR) brachytherapy has great promise, because it eliminates radiation exposure, allows short treatment times, and can be performed on a...

journal_title：Technology in cancer research & treatment

authors： Nag S

更新日期：2004-06-01 00:00:00

abstract：:The aim of this paper is to study the feasibility for determining the individual internal target volume (ITV) for hepatocellular carcinoma (HCC) using 3DCT associated with active breathing coordinator (ABC), comparing the ITVs defined by 3DCT associated with ABC and 4DCT. Thirteen patients with HCC after transarterial...

journal_title：Technology in cancer research & treatment

authors： Gong G,Yin Y,Xing L,Guo Y,Chen J,Liu T,Lu J,Ma C,Sun T,Bai T,Zhang G,Deng W

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the mechanisms involved with miRNA-708 and its targeting of bone morphogenetic protein and activin membrane-bound inhibitor in cell proliferation, migration, and apoptosis in mice with melanoma via the Wnt and transforming growth factor β signaling pathways. METHODS:Sixt...

journal_title：Technology in cancer research & treatment

authors： Lu HJ,Yan J,Jin PY,Zheng GH,Zhang HL,Bai M,Wu DM,Lu J,Zheng YL

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:We compared radiotherapy plans among helical tomotherapy (HT), volumetric-modulated arc therapy (VMAT), and intensity-modulated proton therapy (IMPT) for angiosarcoma of the scalp (AS). METHODS:We conducted a planning study for 19 patients with AS. The clinical target volume (CTV) 1 and CTV2 were defined as ...

journal_title：Technology in cancer research & treatment

authors： Mizuno T,Tomita N,Takaoka T,Tomida M,Fukuma H,Tsuchiya T,Shibamoto Y

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Acute myeloid leukemia (AML) represents a hematological cancer. The aim of the investigation was to probe the regulatory relevance of long non-coding RNA (lncRNA) aspartyl-tRNA synthetase anti-sense 1 (DARS-AS1)/microRNA-425 (miR-425)/transforming growth factor-beta 1 (TGFB1) to the development of AML. METHO...

journal_title：Technology in cancer research & treatment

authors： Dou B,Jiang Z,Chen X,Wang C,Wu J,An J,Sheng G

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To investigate the application value of apparent diffusion coefficient value in the pathological type, histologic grade, and presence of lymph node metastases of esophageal carcinoma. MATERIALS AND METHODS:Eighty-six patients with pathologically confirmed esophageal carcinoma were divided into different grou...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Bai G,Guo L,Chen W

更新日期：2019-01-01 00:00:00

abstract：:Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor with generally disappointing results in terms of survival, however, there are occasional long-term survivors probably due to the biologic characteristics of the disease. Standard uptake value (SUV) of [(18)F] Fluorodeoxyglucose (FDG) evaluated by phot...

journal_title：Technology in cancer research & treatment

authors： Genestreti G,Moretti A,Piciucchi S,Tiseo M,Bersanelli M,Scarlattei M,Scarpi E,Dubini A,Matteucci F,Sanna S

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Disabled homolog 2-interacting protein is a new member of the Ras GTPase superfamily involved in the regulation of cell proliferation, apoptosis, and metastasis. However, the expression of disabled homolog 2-interacting protein in renal cell carcinoma, its correlation with cancer prognosis, and tumor infiltr...

journal_title：Technology in cancer research & treatment

authors： Cao H,Zhang J,Wang W

更新日期：2020-01-01 00:00:00

abstract：:In recent years, the imaging of drug-induced apoptosis has become one of the centers of interest in experimental and clinical research. In particular, the accurate monitoring of chemosensitivity as well as the early prediction of chemoresistance in response to various pro-apoptotic interventions are critical requireme...

journal_title：Technology in cancer research & treatment

authors： Belhocine T,Steinmetz N,Li C,Green A,Blankenberg FG

更新日期：2004-02-01 00:00:00

abstract：:Spinal metastases are a common manifestation of malignant tumors that can cause severe pain, spinal cord compression, pathological fractures, and hypercalcemia, and these clinical manifestations will ultimately reduce the health-related quality of life and even shorten life expectancy in patient with cancer. Effective...

journal_title：Technology in cancer research & treatment

authors： Zhang HR,Li JK,Yang XG,Qiao RQ,Hu YC

更新日期：2020-01-01 00:00:00

abstract：:Results for treating glomus jugulare tumors with radiosurgery have been limited by short follow-up and small number of patients. We report our experience using LINAC or CyberKnife in 21 tumors with a median follow-up of 66 months (Mean follow-up of 60 months). In addition, we have a subset of eight patients that were ...

journal_title：Technology in cancer research & treatment

authors： Lim M,Bower R,Nangiana JS,Adler JR,Chang SD

更新日期：2007-10-01 00:00:00

abstract：:This review addresses the epidemiology, historical reports, current issues, data and controversies involved in the management of brain metastases. The literature regarding surgery, whole brain radiation therapy, stereotactic radiosurgery or some combination of those treatments is discussed as well as issues of cost-ef...

journal_title：Technology in cancer research & treatment

authors： Sperduto PW

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:There is mounting evidence that microRNAs play an important role in nasopharyngeal carcinoma, which is widely prevalent in South China and is the most prevalent metastatic cancer among head and neck cancers. Recently, it has been shown that miR-494 is involved in the progression and prognosis of nasopharynge...

journal_title：Technology in cancer research & treatment

authors： He H,Liao X,Yang Q,Liu Y,Peng Y,Zhong H,Yang J,Zhang H,Yu Z,Zuo Y,Guan C,Xu Z

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Osteosarcoma is a common malignant bone tumor that is frequently found in the long bones of children and adolescents. The aim of this study is to examine long noncoding RNA-steroid receptor RNA activator 1 expression in osteosarcoma to explore the biological function of long noncoding RNA steroid receptor RNA...

journal_title：Technology in cancer research & treatment

authors： Guo W,Jiang H,Li H,Li F,Yu Q,Liu Y,Jiang W,Zhang M

更新日期：2019-01-01 00:00:00

abstract：:Traditional imaging techniques, such as computed tomography (CT), have high spatial resolution for changes in the anatomy or structure of organs, but are not very useful for detecting early biochemical changes. Conversely, positron emission tomography (PET) relies on changes in molecular biology to identify the earlie...

journal_title：Technology in cancer research & treatment

authors： Levy RP

更新日期：2006-04-01 00:00:00

abstract：:The increasing evidence supported the role of Enhancer of Zeste Homolog 2 (EZH2) in the cancer development and progression. However, its precise role in the tumorigenesis of Nasopharyngeal Carcinoma (NPC) remains to be elucidated. EZH2 was depleted by retroviral infection in the NPC cells (HK-1, CNE-2, CNE-1 and C666-...

journal_title：Technology in cancer research & treatment

authors： Zhong J,Min L,Huang H,Li L,Li D,Li J,Ma Z,Dai L

更新日期：2013-06-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to compare the prognostic value of the percentage of positive biopsy cores (PPBC), the percentage of cancer volume (PCV), and the maximum involvement of biopsy cores (MIBC) as a prognostic factor in low- and intermediate-risk patients with clinically localized prostate cancer wh...

journal_title：Technology in cancer research & treatment

authors： Slater JM,Bush DA,Grove R,Slater JD

更新日期：2014-06-01 00:00:00

abstract：:Endometrial carcinoma is one of the most common cancers in women. A limited number of endometrial carcinoma cell lines are available for studies of signal transduction pathways and experimental therapeutics in vitro. However, these cell lines have not been comprehensively characterized. In this study, we used genome-w...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Yang D,Cogdell D,Hu L,Xue F,Broaddus R,Zhang W

更新日期：2010-04-01 00:00:00

abstract：:The microRNA-200 (miR-200) family has been reported to be vital for the inhibition of epithelial-to-mesenchymal transition (EMT) in tumor cells. The miR-200 family represents a complex multi-factorial regulatory network which has not been well described in breast cancer. This study aimed to clarify the underlying regu...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Shao N,Yang X,Xie C,Shi Y,Lin Y

更新日期：2020-01-01 00:00:00

abstract：:Positron emission tomography (PET), the imaging of pharmaceuticals labeled with positron-emitting radionuclides, is a rapidly growing modality for the diagnosis and management of cancer. PET yields high-quality images characterizing substrate metabolism, cellular proliferation, receptor density, and other parameters t...

journal_title：Technology in cancer research & treatment

authors： Mandelkern M,Raines J

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:The main objective in studying large-scale cancer omics is to identify molecular mechanisms of cancer and discover novel biomedical targets. This work not only discovers the cancer subtypes in genome scale data by using clustering and classification but also measures their accuracy. METHODS:Initially, candid...

journal_title：Technology in cancer research & treatment

authors： Vasudevan P,Murugesan T

更新日期：2018-01-01 00:00:00

abstract：:The use of electric pulses to transfect cells has recently been extended to show the utility of this procedure in vivo. Electrotransfer has been performed in vivo on several tissue types including skin, blood vessels, liver, tumor, muscle, cornea, brain and spleen. The most widely targeted tissue has been skeletal mus...

journal_title：Technology in cancer research & treatment

authors： Scherman D,Bigey P,Bureau MF

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:To test the feasibility of modified biopsy needles as probes for irreversible electroporation ablation and periprocedural biopsy. METHODS:Core biopsy needles of 16-G/9-cm were customized to serve as experimental ablation probes. Computed tomography-guided percutaneous irreversible electroporation was perfor...

journal_title：Technology in cancer research & treatment

authors： Wimmer T,Srimathveeravalli G,Silk M,Monette S,Gutta N,Maybody M,Erinjery JP,Coleman JA,Solomon SB,Sofocleous CT

更新日期：2016-12-01 00:00:00

abstract：:Colorectal cancer is one of the most common cancers in the world. Protein phosphatase magnesium-dependent 1 d (PPM1D) is aberrantly upregulated in many human carcinoma cells, and recent research has suggested that it could be a potential therapeutic target of cancer. However, the function of PPM1D in colorectal carcin...

journal_title：Technology in cancer research & treatment

authors： Yin H,Yan Z,Liang Y,Liu B,Su Q

更新日期：2013-12-01 00:00:00

abstract：:Proteomics is a rapidly expanding discipline that aims to gain a comprehensive understanding of the expressions, modification, interactions, and regulation of proteins in cells. New high-throughput technologies, such as protein chips and isotope-coded affinity tag peptide labeling, coupled with classic technologies su...

journal_title：Technology in cancer research & treatment

authors： Choi W,Song SW,Zhang W

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:The efficacy of image-guided high-dose rate brachytherapy for cervical cancer is limited by the ineffective rectal sparing devices available commercially and the potential applicator movement. We developed a novel device using a balloon catheter and a belt immobilization system, serving for rectal dose reductio...

journal_title：Technology in cancer research & treatment

authors： Fan Q,Yeung AR,Amdur R,Helmig R,Park J,Li J,Kahler D,Liu C,Lu B

更新日期：2017-06-01 00:00:00