Positron emission tomography in cancer research and treatment.

Abstract:

:Positron emission tomography (PET), the imaging of pharmaceuticals labeled with positron-emitting radionuclides, is a rapidly growing modality for the diagnosis and management of cancer. PET yields high-quality images characterizing substrate metabolism, cellular proliferation, receptor density, and other parameters that can be used to identify cancer and evaluate its response to therapies. The technique mainly utilized in cancer management is FDG-PET, which exploits the abnormal glucose metabolism of cancer cells first characterized by Warburg. We discuss the principles of PET, the currently available instrumentation and radiopharmaceuticals, the efficacy of FDG-PET in the management of cancer, and the prospects for near-term advances in cancer using PET.

authors

Mandelkern M,Raines J

doi

10.1177/153303460200100603

keywords:

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

423-39

issue

6

eissn

1533-0346

issn

1533-0338

pii

d=3007&c=4098&p=11323&do=detail

journal_volume

1

pub_type

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