Adenovirus-mediated ING4 Gene Transfer in Osteosarcoma Suppresses Tumor Growth via Induction of Apoptosis and Inhibition of Tumor Angiogenesis.

abstract：:Despite remarkable progress in diagnosis and treatment, malignant glioma, a highly lethal cancer of the central nervous system, remains incurable. Although glioma stem-like cells (GSCs) represent a relatively small fraction of the cells in malignant glioma, they can proliferate and self renew extensively, being crucia...

journal_title：Technology in cancer research & treatment

authors： Xu ZY,Li XQ,Chen S,Cheng Y,Deng JM,Wang ZG

更新日期：2012-12-01 00:00:00

abstract：:The incidence of optic neuropathy after stereotactic radiosurgery (SRS) is related to the total dose, fraction size, and treatment volume. Theoretically, fractionated SRS can decrease this risk. In this paper, we report our technique for fractionated SRS and assess its potential role in the management of tumors locate...

journal_title：Technology in cancer research & treatment

authors： Mehta VK,Lee QT,Chang SD,Cherney S,Adler JR Jr

更新日期：2002-06-01 00:00:00

abstract：PURPOSE:In this study, we aimed to evaluate the prognostic value of fluorodeoxyglucose uptake in the lung parenchyma and the presence of subclinical interstitial lung disease on computed tomography as predictive factors for survival following stereotactic body radiation therapy in patients with stage I non-small cell l...

journal_title：Technology in cancer research & treatment

authors： Satoh Y,Motosugi U,Saito A,Omiya Y,Onishi H

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To investigate the role of intensity-modulated proton therapy (IMPT) for hepatocellular carcinoma (HCC) patients to be treated with stereotactic body radiation therapy (SBRT) in a risk-adapted dose prescription regimen. METHODS:A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escala...

journal_title：Technology in cancer research & treatment

authors： Cozzi L,Comito T,Loi M,Fogliata A,Franzese C,Franceschini D,Clerici E,Reggiori G,Tomatis S,Scorsetti M

更新日期：2020-01-01 00:00:00

abstract：:Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...

journal_title：Technology in cancer research & treatment

authors： ten Hagen TL,Eggermont AM

更新日期：2003-06-01 00:00:00

abstract：:Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient studies been performed investigating the part of long noncoding R...

journal_title：Technology in cancer research & treatment

authors： Sun KK,Shen XJ,Yang D,Jiao Y,Wu XY

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:There is mounting evidence that microRNAs play an important role in nasopharyngeal carcinoma, which is widely prevalent in South China and is the most prevalent metastatic cancer among head and neck cancers. Recently, it has been shown that miR-494 is involved in the progression and prognosis of nasopharynge...

journal_title：Technology in cancer research & treatment

authors： He H,Liao X,Yang Q,Liu Y,Peng Y,Zhong H,Yang J,Zhang H,Yu Z,Zuo Y,Guan C,Xu Z

更新日期：2018-01-01 00:00:00

abstract：:This study was performed to observe the effect of the combination of nimotuzumab with radiation or gemcitabine-based chemoradiation on antipancreatic cancer cell therapy. Pancreatic cancer cells (PANC-1) were treated with nimotuzumab alone or combined with radiation (2, 4, or 8 Gy), which was either with or without ge...

journal_title：Technology in cancer research & treatment

authors： Gao C,Wu X,Yan Y,Meng L,Shan D,Li Y,Han B

更新日期：2016-06-01 00:00:00

abstract：:Proteomics is a rapidly expanding discipline that aims to gain a comprehensive understanding of the expressions, modification, interactions, and regulation of proteins in cells. New high-throughput technologies, such as protein chips and isotope-coded affinity tag peptide labeling, coupled with classic technologies su...

journal_title：Technology in cancer research & treatment

authors： Choi W,Song SW,Zhang W

更新日期：2002-08-01 00:00:00

abstract：:Intraoperative magnetic resonance imaging has been applied to a number of neurosurgical disease processes since the late 1990's. The ability to visualize the operative site in near-real time has added a significant degree of safety to the treatment of lesions such as a cystic craniopharyngioma which can be located in ...

journal_title：Technology in cancer research & treatment

authors： Hall WA,Liu H,Truwit CL

更新日期：2003-02-01 00:00:00

abstract：:The purpose of this study was to evaluate the feasibility and treatment plans of intensity-modulated radiation therapy using helical tomotherapy (HT) for brain metastases. Twenty-three patients with 1 to 4 brain metastases were treated with HT. In combination with whole-brain radiotherapy (simultaneous plans), metasta...

journal_title：Technology in cancer research & treatment

authors： Tomita N,Kodaira T,Tachibana H,Nakamura T,Nakahara R,Inokuchi H,Shibamoto Y

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the prognostic role of neutrophil to lymphocyte ratio in ovarian cancer. Growing number of articles reported the relationship between neutrophil to lymphocyte ratio and prognosis in ovarian cancer, but the results remains inconclusive. The meta-analysis was conducted to...

journal_title：Technology in cancer research & treatment

authors： Chen G,Zhu L,Yang Y,Long Y,Li X,Wang Y

更新日期：2018-01-01 00:00:00

abstract：:As one of the common cancers that threaten human life, the recurrence and metastasis of colorectal cancer seriously affect the prognosis of patients. Although new drugs and comprehensive treatments have been adopted, the current treatment effect on this tumor, especially in advanced colorectal cancer, is still not sat...

journal_title：Technology in cancer research & treatment

authors： Ma YS,Li W,Liu Y,Shi Y,Lin QL,Fu D

更新日期：2020-01-01 00:00:00

abstract：:The combined effect of high energy shock waves (HESW), generated by a piezoelectric device, and paclitaxel on Mat B-III rat breast cancer cells in vitro and in an in vivo animal model is presented. A significant reduction of in vitro Mat B-III cell proliferation versus cells treated with paclitaxel alone was observed ...

journal_title：Technology in cancer research & treatment

authors： Canaparo R,Serpe L,Zara GP,Chiarle R,Berta L,Frairia R

更新日期：2008-04-01 00:00:00

abstract：:The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C(60)(OH)(24) in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Experiment was performed on adult female Spra...

journal_title：Technology in cancer research & treatment

authors： Injac R,Perse M,Boskovic M,Djordjevic-Milic V,Djordjevic A,Hvala A,Cerar A,Strukelj B

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:The efficacy of image-guided high-dose rate brachytherapy for cervical cancer is limited by the ineffective rectal sparing devices available commercially and the potential applicator movement. We developed a novel device using a balloon catheter and a belt immobilization system, serving for rectal dose reductio...

journal_title：Technology in cancer research & treatment

authors： Fan Q,Yeung AR,Amdur R,Helmig R,Park J,Li J,Kahler D,Liu C,Lu B

更新日期：2017-06-01 00:00:00

abstract：:Human epidermal growth factor 2 (HER2)+ breast cancer is considered the most dangerous type of breast cancers. Herein, we used bioinformatics methods to identify potential key genes in HER2+ breast cancer to enable its diagnosis, treatment, and prognosis prediction. Datasets of HER2+ breast cancer and normal tissue sa...

journal_title：Technology in cancer research & treatment

authors： Weng Y,Liang W,Ji Y,Li Z,Jia R,Liang Y,Ning P,Xu Y

更新日期：2021-01-01 00:00:00

abstract：:We previously showed that microRNA-182 (miR-182) might promote cell proliferation and migration in triple-negative breast cancer (TNBC). This study aimed to investigate circular RNAs (circRNAs) that interact with miR-182 and play important roles in TNBC. Thirty patients with TNBC were enrolled. One pair of tumor and a...

journal_title：Technology in cancer research & treatment

authors： Yu J,Shen W,Xu J,Gong B,Gao B,Zhu J

更新日期：2020-01-01 00:00:00

abstract：AIM:To explore the relationship of clinicopathological features and the proteins of C-met expression in the prognosis of cholangiocarcinoma. METHODS:Clinical data and the completed follow-up information of patients with cholangiocarcinoma who underwent cholangiocarcinoma operation from January 2004 to December 2010 we...

journal_title：Technology in cancer research & treatment

authors： Mao ZY,Zhu GQ,Ren L,Guo XC,Su D,Bai L

更新日期：2016-04-01 00:00:00

abstract：:This review addresses the epidemiology, historical reports, current issues, data and controversies involved in the management of brain metastases. The literature regarding surgery, whole brain radiation therapy, stereotactic radiosurgery or some combination of those treatments is discussed as well as issues of cost-ef...

journal_title：Technology in cancer research & treatment

authors： Sperduto PW

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:We aimed to identify the expression of Sal-like 4 (SALL4) in breast cancer tissues and to explore the role of this gene in the carcinogenesis of breast cancer cells. METHODS:A total of 62 paired breast cancer and noncancerous tissue samples were obtained from patients with breast cancer. SALL4 expression pat...

journal_title：Technology in cancer research & treatment

authors： Liu C,Yao F,Mao X,Li W,Chen H

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The main objective in studying large-scale cancer omics is to identify molecular mechanisms of cancer and discover novel biomedical targets. This work not only discovers the cancer subtypes in genome scale data by using clustering and classification but also measures their accuracy. METHODS:Initially, candid...

journal_title：Technology in cancer research & treatment

authors： Vasudevan P,Murugesan T

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. MATERIALS AND METHODS:A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identi...

journal_title：Technology in cancer research & treatment

authors： Korpics M,Johnson P,Patel R,Surucu M,Choi M,Emami B,Roeske JC

更新日期：2016-12-01 00:00:00

abstract：:Complement 3a (C3a) and complement 5a (C5a), small cleavage fragments generated by complement activation, has been previously shown to be obviously up-regulated in highly metastatic hepatocellular carcinoma (HCC) cells. However, their functional roles in HCC cells remains unclear. Here, we investigated the biological ...

journal_title：Technology in cancer research & treatment

authors： Chen B,Zhou W,Tang C,Wang G,Yuan P,Zhang Y,Bhushan SC,Ma J,Leng J

更新日期：2020-01-01 00:00:00

abstract：:The use of electric pulses to transfect cells has recently been extended to show the utility of this procedure in vivo. Electrotransfer has been performed in vivo on several tissue types including skin, blood vessels, liver, tumor, muscle, cornea, brain and spleen. The most widely targeted tissue has been skeletal mus...

journal_title：Technology in cancer research & treatment

authors： Scherman D,Bigey P,Bureau MF

更新日期：2002-10-01 00:00:00

abstract：:The ultrasound-guided diffuse optical tomography is a noninvasive imaging technique for breast cancer diagnosis and treatment monitoring. The technique uses a handheld probe capable of providing measurements of multiple wavelengths in a few seconds. These measurements are used to estimate optical absorptions of lesion...

journal_title：Technology in cancer research & treatment

authors： Althobaiti M,Vavadi H,Zhu Q

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:We recently developed a novel, open-source in vivo dosimetry that uses the electronic portal imaging device to detect dose delivery discrepancies. We applied our method on patients with rectal cancer treated on a belly board device. METHODS:In vivo dosimetry was performed on 10 patients with rectal cancer trea...

journal_title：Technology in cancer research & treatment

authors： Peca S,Sinha RS,Brown DW,Smith WL

更新日期：2017-12-01 00:00:00

abstract：:We investigated the technique, early results and toxicity of curative stereotactic radiotherapy with the CyberKnife (Accuray Incorporated, Sunnyvale, California, USA) in 15 extracranial, extrapulmonary, extrahepatic, and extraspinal tumors. Fourteen tumors were located close to the bowel or esophagus. The PTV = GTV + ...

journal_title：Technology in cancer research & treatment

authors： Nuyttens JJ,Prevost JB,Van der Voort van Zijp NC,Hoogeman M,Levendag PC

更新日期：2007-12-01 00:00:00

abstract：:Since "Warburg effect" has been firstly uncovered in cancer cells in 1956, mounting evidence has supported the molecular mechanism underlying the energy metabolism in induced chemoresistance in cancers. MicroRNAs can mediate fine-tuning of genes in physiological process. MicroRNAs' energy metabolic role in chemoresist...

journal_title：Technology in cancer research & treatment

authors： Ye J,Zou M,Li P,Liu H

更新日期：2018-01-01 00:00:00

abstract：:Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is able to detect breast cancer with high sensitivity. Furthermore, this method provides functional information on tissue composition and vascularization. This study aims to identify the potential of DCE-MRI to predict distant metastasis in breast cancer p...

journal_title：Technology in cancer research & treatment

authors： Baltzer PA,Zoubi R,Burmeister HP,Gajda M,Camara O,Kaiser WA,Dietzel M

更新日期：2012-12-01 00:00:00