In vivo biodistribution of dendrimers and dendrimer nanocomposites -- implications for cancer imaging and therapy.

abstract：OBJECTIVE:To evaluate and quantify the planning performance of automatic planning (AP) with manual planning (MP) for nasopharyngeal carcinoma in the RayStation treatment planning system (TPS). METHODS:A progressive and effective design method for AP of nasopharyngeal carcinoma was realized through automated scripts in...

journal_title：Technology in cancer research & treatment

authors： Yang Y,Shao K,Zhang J,Chen M,Chen Y,Shan G

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:The efficacy of image-guided high-dose rate brachytherapy for cervical cancer is limited by the ineffective rectal sparing devices available commercially and the potential applicator movement. We developed a novel device using a balloon catheter and a belt immobilization system, serving for rectal dose reductio...

journal_title：Technology in cancer research & treatment

authors： Fan Q,Yeung AR,Amdur R,Helmig R,Park J,Li J,Kahler D,Liu C,Lu B

更新日期：2017-06-01 00:00:00

abstract：:The study of the effectiveness of cryotherapy as a curative treatment for prostate cancer has often relied on the use of either in vitro cell culture monolayers or animal models. While the data gleaned from these studies have been valuable, each model has inherent limitations. In order to bridge the gap between in vit...

journal_title：Technology in cancer research & treatment

authors： Robilotto AT,Clarke D,Baust JM,Van Buskirk RG,Gage AA,Baust JG

更新日期：2007-04-01 00:00:00

abstract：:One of the most lethal carcinomas is pancreatic cancer. As standard treatment using chemotherapy and radiation has shown limited success, thermal regimens (cryotherapy or heat ablation) are emerging as viable alternatives. Although promising, our understanding of pancreatic cancer response to thermal ablation remains ...

journal_title：Technology in cancer research & treatment

authors： Baumann KW,Baust JM,Snyder KK,Baust JG,Van Buskirk RG

更新日期：2017-08-01 00:00:00

abstract：:Brachytherapy has the advantage of delivering a high dose to the tumor while sparing the surrounding normal tissues. With proper case selection and delivery technique, high-dose-rate (HDR) brachytherapy has great promise, because it eliminates radiation exposure, allows short treatment times, and can be performed on a...

journal_title：Technology in cancer research & treatment

authors： Nag S

更新日期：2004-06-01 00:00:00

abstract：:Complement 3a (C3a) and complement 5a (C5a), small cleavage fragments generated by complement activation, has been previously shown to be obviously up-regulated in highly metastatic hepatocellular carcinoma (HCC) cells. However, their functional roles in HCC cells remains unclear. Here, we investigated the biological ...

journal_title：Technology in cancer research & treatment

authors： Chen B,Zhou W,Tang C,Wang G,Yuan P,Zhang Y,Bhushan SC,Ma J,Leng J

更新日期：2020-01-01 00:00:00

abstract：:The aim of this study is to evaluate the volume differences between contrast-enhanced CT-based left ventricle (LV) and PET-CT-based LV and assess the impact of dose on the substructure volume differences in patients with left breast cancer treated with adjuvant radiotherapy. From October 2008 to February 2009, 14 pati...

journal_title：Technology in cancer research & treatment

authors： Yu XL,Zhang Q,Chen JY,Zhang Z,Wang JZ,Hu WG,Pan ZQ,Hu SL,Zhang YJ,Feng Y,Shao ZM,Orecchia R,Guo XM

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:A meta-analysis was conducted to evaluate the diagnostic performance of contrast-enhanced ultrasonography using the contrast agent SonoVue to differentiate benign from malignant breast lesions. METHOD:A comprehensive search of the literature was performed using the Embase, PubMed, and Web of Science databases ...

journal_title：Technology in cancer research & treatment

authors： Lu J,Zhou P,Jin C,Xu L,Zhu X,Lian Q,Gong X

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate long-term outcomes and prognostic factors of laparoscopic microwave ablation as a first-line treatment for hepatocellular carcinoma located at the liver surface not feasible for percutaneous ablation. METHODS:51 consecutive patients receiving laparoscopic microwave ablation in our cente...

journal_title：Technology in cancer research & treatment

authors： Wang T,Zhang XY,Lu X,Zhai B

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To investigate the application value of apparent diffusion coefficient value in the pathological type, histologic grade, and presence of lymph node metastases of esophageal carcinoma. MATERIALS AND METHODS:Eighty-six patients with pathologically confirmed esophageal carcinoma were divided into different grou...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Bai G,Guo L,Chen W

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Nasopharyngeal carcinoma is highly endemic in Southeast China. Circulating tumor cell is an important biomarker in the prognosis of variety kinds of cancers. Overexpression of fibronectin 1 was observed in variety kinds of malignancies and may contribute to progress and metastasis of the cancers. The current ...

journal_title：Technology in cancer research & treatment

authors： Yu Y,Lin ZX,Li HW,Luo HQ,Yang DH,Zhou HC,Jiang DX,Zhan DC,Yang L,Liang XY,Yu ZH,Chen ZH

更新日期：2020-01-01 00:00:00

abstract：:The integrated use of optical technologies for patient monitoring is addressed in the framework of time-resolved treatment delivery for scanned ion beam therapy. A software application has been designed to provide the therapy control system (TCS) with a continuous geometrical feedback by processing the external surrog...

journal_title：Technology in cancer research & treatment

authors： Fattori G,Saito N,Seregni M,Kaderka R,Pella A,Constantinescu A,Riboldi M,Steidl P,Cerveri P,Bert C,Durante M,Baroni G

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To confirm the feasibility and accuracy of the method for evaluating blood supply and embolization rate of liver cancer based on I-flow software through animal experiments and clinical study. METHODS:Rabbits underwent selective angiography under different perfusion conditions in the same kidney. The blood su...

journal_title：Technology in cancer research & treatment

authors： Li Y,Zhou F,Liu F,Wang M,Xing W

更新日期：2020-01-01 00:00:00

abstract：:Breast cancer remains one of the leading causes of cancer-associated death in women. MiR-27a is highly expressed in breast cancer tissue. However, the underlying mechanisms that promote breast cancer progression are unknown. In this study, we investigated the regulatory mechanisms of miR-27a and its target glycogen Sy...

journal_title：Technology in cancer research & treatment

authors： Chen H,Zhang Y,Cao X,Mou P

更新日期：2020-01-01 00:00:00

abstract：:The incidence of optic neuropathy after stereotactic radiosurgery (SRS) is related to the total dose, fraction size, and treatment volume. Theoretically, fractionated SRS can decrease this risk. In this paper, we report our technique for fractionated SRS and assess its potential role in the management of tumors locate...

journal_title：Technology in cancer research & treatment

authors： Mehta VK,Lee QT,Chang SD,Cherney S,Adler JR Jr

更新日期：2002-06-01 00:00:00

abstract：:Endometrial carcinoma is one of the most common cancers in women. A limited number of endometrial carcinoma cell lines are available for studies of signal transduction pathways and experimental therapeutics in vitro. However, these cell lines have not been comprehensively characterized. In this study, we used genome-w...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Yang D,Cogdell D,Hu L,Xue F,Broaddus R,Zhang W

更新日期：2010-04-01 00:00:00

abstract：:Stereotactic radiosurgery (SRS) refers to a single radiation treatment delivering a high dose to an intra-cranial target localized in three-dimensions by CT and/or MRI imaging. Traditionally, immobilization of the patient's head has been achieved using a rigid stereotactic head frame as the key step in allowing for ac...

journal_title：Technology in cancer research & treatment

authors： Sahgal A,Ma L,Chang E,Shiu A,Larson DA,Laperriere N,Yin FF,Tsao M,Menard C,Basran P,Létourneau D,Heydarian M,Beachey D,Shukla V,Cusimano M,Hodaie M,Zadeh G,Bernstein M,Schwartz M

更新日期：2009-08-01 00:00:00

abstract：:Many conventional chemotherapeutic drugs, as well as DNA for cancer gene therapy, require efficient access to the cell interior to be effective. The cell membrane is a formidable barrier to many of these drugs, including therapeutic DNA constructs. Electropermeabilization (EP, often used synonymously with "electropora...

journal_title：Technology in cancer research & treatment

authors： Rabussay DP,Nanda GS,Goldfarb PM

更新日期：2002-02-01 00:00:00

abstract：:To describe the technological background, the accuracy, and clinical feasibility for single session lung radiosurgery using a real-time robotic system with respiratory tracking. The latest version of image-guided real-time respiratory tracking software (Synchrony, Accuray Incorporated, Sunnyvale, CA) was applied and i...

journal_title：Technology in cancer research & treatment

authors： Muacevic A,Drexler C,Wowra B,Schweikard A,Schlaefer A,Hoffmann RT,Wilkowski R,Winter H,Reiser M

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:The incidence of colorectal cancer is increasing every year, and autophagy may be related closely to the pathogenesis of colorectal cancer. Autophagy is a natural catabolic mechanism that allows the degradation of cellular components in eukaryotic cells. However, autophagy plays a dual role in tumorigenesis. ...

journal_title：Technology in cancer research & treatment

authors： Liu TT,Liu SM

更新日期：2020-01-01 00:00:00

abstract：:At external beam radiotherapy, stereoscopic X-ray imaging system is responsible as tumor motion information provider. This system takes X-ray images intermittently from tumor position (1) at pretreatment step to provide training data set for model construction and (2) during treatment to control the accuracy of correl...

journal_title：Technology in cancer research & treatment

authors： Esmaili Torshabi A,Ghorbanzadeh L

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:Neoadjuvant chemoradiotherapy (nCRT) followed by operation has become the standard treatment for locally advanced rectal cancer (LARC). However, considering the possible toxicity and complications of radiochemotherapy, nCRT is seldom used for the elderly. The purpose of this study was to assess the safety ...

journal_title：Technology in cancer research & treatment

authors： Liu H,Li C,Zhao Z,Guan X,Yang M,Liu Z,Tang Y,Jiang Z,Wang X

更新日期：2020-01-01 00:00:00

abstract：:Recombinant Newcastle Disease Virus (rNDV) has shown oncolytic therapeutic effect in preclinical studies. Previous data indicate that rNDV carrying IL2 has shown promise in cancer therapy. Due to the significant side effects of IL2, IL15 has been introduced into cancer therapy. A number of studies have suggested that ...

journal_title：Technology in cancer research & treatment

authors： Niu Z,Bai F,Sun T,Tian H,Yu D,Yin J,Li S,Li T,Cao H,Yu Q,Wu Y,Ren G,Li D

更新日期：2015-10-01 00:00:00

abstract：:This successor phase II study evaluates the tolerability and efficacy of concomitant hyperfractionated radiation therapy (HFX-RT) and double dose intra-arterial (IA) cisplatin in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). In doing so, this study represents further resurgence o...

journal_title：Technology in cancer research & treatment

authors： Regine WF,Valentino J,Arnold SM,Sloan D,Kenady D,Strottmann J,Mohiuddin M

更新日期：2002-04-01 00:00:00

abstract：:Numerous beam directions using 3-D conformal techniques can be employed in treating tumors in the posterior fossa, each with characteristic normal tissue exposure along the entrance and exit trajectory. A representative variety of beam configurations were modeled in a modern computer planning system initially with the...

journal_title：Technology in cancer research & treatment

authors： Timmerman RD,Ewing M,Donges M,Wilson J,Jakacki R,Randall ME

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:Osteosarcoma is a common malignant bone tumor that is frequently found in the long bones of children and adolescents. The aim of this study is to examine long noncoding RNA-steroid receptor RNA activator 1 expression in osteosarcoma to explore the biological function of long noncoding RNA steroid receptor RNA...

journal_title：Technology in cancer research & treatment

authors： Guo W,Jiang H,Li H,Li F,Yu Q,Liu Y,Jiang W,Zhang M

更新日期：2019-01-01 00:00:00

abstract：:In recent years, the imaging of drug-induced apoptosis has become one of the centers of interest in experimental and clinical research. In particular, the accurate monitoring of chemosensitivity as well as the early prediction of chemoresistance in response to various pro-apoptotic interventions are critical requireme...

journal_title：Technology in cancer research & treatment

authors： Belhocine T,Steinmetz N,Li C,Green A,Blankenberg FG

更新日期：2004-02-01 00:00:00

abstract：:The present approach at our institution for the treatment of patients with colorectal (CRC) cancer and with liver metastases planned for metastasectomy is the neoadjuvant administration of Bevacizumab with Irinotecan based therapy. Metabolic imaging of tumor viability with 18F-fluorodeoxyglucose (FDG) positron emissio...

journal_title：Technology in cancer research & treatment

authors： Goshen E,Davidson T,Zwas ST,Aderka D

更新日期：2006-02-01 00:00:00

abstract：:eLiposomes encapsulate a perfluorocarbon nanoemulsion droplet inside a liposome. Ultrasound is then used as a trigger mechanism to vaporize the perfluorocarbon, break the liposome, and release the desired drug to the tumor tissue. The purpose of this research is to show that eLiposomes synthesized using perfluoropenta...

journal_title：Technology in cancer research & treatment

authors： Husseini GA,Pitt WG,Javadi M

更新日期：2015-08-01 00:00:00

abstract：:The treatment of patients with malignant brain tumors, in particular glioblastoma multiforme (GBM) is very challenging because of their diffuse infiltrative nature and the cytological heterogeneity. The median survival of patients with newly diagnosed GBM is only 12-15 months, and only 8-12% of them survive for two ye...

journal_title：Technology in cancer research & treatment

authors： Kioi M,Husain SR,Croteau D,Kunwar S,Puri RK

更新日期：2006-06-01 00:00:00