MiR-27a Facilitates Breast Cancer Progression via GSK-3β.

abstract：:Results for treating glomus jugulare tumors with radiosurgery have been limited by short follow-up and small number of patients. We report our experience using LINAC or CyberKnife in 21 tumors with a median follow-up of 66 months (Mean follow-up of 60 months). In addition, we have a subset of eight patients that were ...

journal_title：Technology in cancer research & treatment

authors： Lim M,Bower R,Nangiana JS,Adler JR,Chang SD

更新日期：2007-10-01 00:00:00

abstract：:Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...

journal_title：Technology in cancer research & treatment

authors： ten Hagen TL,Eggermont AM

更新日期：2003-06-01 00:00:00

abstract：:The aim of this study was to evaluate the relationship of prognosis of patients with multiple myeloma having extramedullary involvement (EMM) with the 18F- fluorodeoxyglucose(18F-FDG) maximum standardized uptake value and the expression of Ki-67 in biopsy samples. Sixty-five patients were newly diagnosed with multiple...

journal_title：Technology in cancer research & treatment

authors： Li Q,Ma J,Li H,Xu W,Cao Z,Liu S,Chen L,Gao S,Yan T,Li D,Wang X,Yue Y,Zhao Z,Wang X,Yang H,Zhao H,Yu Y,Zhang Y,Fan F,Wang Y

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To evaluate 2 simultaneous integrated boost treatment planning techniques using helical tomotherapy for breast conserving therapy with regard to acute skin toxicity and dosimetry. METHODS:Thirty-two patients were studied. The original approach was for 16 patients and incorporated a directional block of the ips...

journal_title：Technology in cancer research & treatment

authors： Wojcieszynski AP,Olson AK,Rong Y,Kimple RJ,Yadav P

更新日期：2016-04-01 00:00:00

abstract：:Planning robotic radiosurgery treatments for multiple (n > 3) metastatic brain lesions is challenging due to the need of satisfying a large number of dose-volume constraints and the requirement of prescribing different dose levels to individual targets. In this study, we developed a sequential two-step optimization te...

journal_title：Technology in cancer research & treatment

authors： Ma L,Sahgal A,Hwang A,Hu W,Descovich M,Chuang C,Barani I,Sneed PK,McDermott M,Larson DA

更新日期：2011-08-01 00:00:00

abstract：:Hydroxycamptothecin-encapsulated chitosan (HC) nanospheres were prepared by Shirasu porous glass (SPG) membrane emulsification technique. The properties and morphology of HC nanospheres were characterized. The diameter of the nanospheres could be controlled within a narrow distribution according to the pore-size of SP...

journal_title：Technology in cancer research & treatment

authors： Han J,Hou ZQ,Wang YG,Guo X

更新日期：2015-02-01 00:00:00

abstract：:Positron emission tomography (PET), the imaging of pharmaceuticals labeled with positron-emitting radionuclides, is a rapidly growing modality for the diagnosis and management of cancer. PET yields high-quality images characterizing substrate metabolism, cellular proliferation, receptor density, and other parameters t...

journal_title：Technology in cancer research & treatment

authors： Mandelkern M,Raines J

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Nonthermal irreversible electroporation is a minimally invasive surgery technology that employs high and brief electric fields to ablate undesirable tissues. Nonthermal irreversible electroporation can ablate only cells while preserving intact functional properties of the extracellular structures. Therefore,...

journal_title：Technology in cancer research & treatment

authors： Lv Y,Zhang Y,Huang J,Wang Y,Rubinsky B

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:A meta-analysis was conducted to evaluate the diagnostic performance of contrast-enhanced ultrasonography using the contrast agent SonoVue to differentiate benign from malignant breast lesions. METHOD:A comprehensive search of the literature was performed using the Embase, PubMed, and Web of Science databases ...

journal_title：Technology in cancer research & treatment

authors： Lu J,Zhou P,Jin C,Xu L,Zhu X,Lian Q,Gong X

更新日期：2020-01-01 00:00:00

abstract：:This study was performed to observe the effect of the combination of nimotuzumab with radiation or gemcitabine-based chemoradiation on antipancreatic cancer cell therapy. Pancreatic cancer cells (PANC-1) were treated with nimotuzumab alone or combined with radiation (2, 4, or 8 Gy), which was either with or without ge...

journal_title：Technology in cancer research & treatment

authors： Gao C,Wu X,Yan Y,Meng L,Shan D,Li Y,Han B

更新日期：2016-06-01 00:00:00

abstract：:Spinal metastases are a common manifestation of malignant tumors that can cause severe pain, spinal cord compression, pathological fractures, and hypercalcemia, and these clinical manifestations will ultimately reduce the health-related quality of life and even shorten life expectancy in patient with cancer. Effective...

journal_title：Technology in cancer research & treatment

authors： Zhang HR,Li JK,Yang XG,Qiao RQ,Hu YC

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To confirm the feasibility and accuracy of the method for evaluating blood supply and embolization rate of liver cancer based on I-flow software through animal experiments and clinical study. METHODS:Rabbits underwent selective angiography under different perfusion conditions in the same kidney. The blood su...

journal_title：Technology in cancer research & treatment

authors： Li Y,Zhou F,Liu F,Wang M,Xing W

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Neoadjuvant chemoradiotherapy (nCRT) followed by operation has become the standard treatment for locally advanced rectal cancer (LARC). However, considering the possible toxicity and complications of radiochemotherapy, nCRT is seldom used for the elderly. The purpose of this study was to assess the safety ...

journal_title：Technology in cancer research & treatment

authors： Liu H,Li C,Zhao Z,Guan X,Yang M,Liu Z,Tang Y,Jiang Z,Wang X

更新日期：2020-01-01 00:00:00

abstract：:Intraoperative MRI (iMRI) is used in glioma surgery mainly to determine the extent of resection, allowing surgeons to immediately continue resection in case of residual tumor tissue. The aim of this study is to report on the influence of the use of iMRI on the extent of resection and survival of patients with glioblas...

journal_title：Technology in cancer research & treatment

authors： Senft C,Franz K,Blasel S,Oszvald A,Rathert J,Seifert V,Gasser T

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The incidence of nasopharyngeal carcinoma is increasing gradually, but the pathogenesis is not completely clear. MicroRNA, a highly conserved endogenous noncoding small molecule RNA, plays an essential role in the regulation of gene expression and is a hotspot in cancer research worldwide. OBJECTIVES:Althou...

journal_title：Technology in cancer research & treatment

authors： Xuefang Z,Ruinian Z,Liji J,Chun Z,Qiaolan Z,Jun J,Yuming C,Junrong H

更新日期：2020-01-01 00:00:00

abstract：:Signal transduction pathways play a crucial role in breast cancer development, progression, and response to different therapies. A major problem in breast cancer therapy is the heterogeneity among different tumor types and cell lines commonly used in preclinical studies. To characterize the signaling pathways of some ...

journal_title：Technology in cancer research & treatment

authors： Akkiprik M,Nicorici D,Cogdell D,Jia YJ,Hategan A,Tabus I,Yli-Harja O,Y D,Sahin A,Zhang W

更新日期：2006-12-01 00:00:00

abstract：:Histological differentiation is a major pathological criterion indicating the risk of tumor invasion and metastasis in patients with hepatocellular carcinoma. The degree of tumor differentiation is controlled by a complex interacting network of associated proteins. The principal aim of the present study is to identify...

journal_title：Technology in cancer research & treatment

authors： Zhao S,Su G,Yang W,Yue P,Bai B,Lin Y,Zhang J,Ba Y,Luo Z,Liu X,Zhao L,Xie Y,Xu Y,Li S,Meng W,Xie X,Li X

更新日期：2017-12-01 00:00:00

abstract：:Endometrial carcinoma is one of the most common cancers in women. A limited number of endometrial carcinoma cell lines are available for studies of signal transduction pathways and experimental therapeutics in vitro. However, these cell lines have not been comprehensively characterized. In this study, we used genome-w...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Yang D,Cogdell D,Hu L,Xue F,Broaddus R,Zhang W

更新日期：2010-04-01 00:00:00

abstract：:Lung cancer remains one of the most common cancer-related deaths worldwide. The cigarette smoking is a risk factor for lung cancer development. Interestingly, the cystic fibrosis transmembrane conductance regulator encoded by CFTR gene, an ATP-binding cassette transporter-class ion channel that conducts chloride and b...

journal_title：Technology in cancer research & treatment

authors： Li H,Ma N,Wang J,Wang Y,Yuan C,Wu J,Luo M,Yang J,Chen J,Shi J,Liu X

更新日期：2018-01-01 00:00:00

abstract：:Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient studies been performed investigating the part of long noncoding R...

journal_title：Technology in cancer research & treatment

authors： Sun KK,Shen XJ,Yang D,Jiao Y,Wu XY

更新日期：2020-01-01 00:00:00

abstract：:Complement 3a (C3a) and complement 5a (C5a), small cleavage fragments generated by complement activation, has been previously shown to be obviously up-regulated in highly metastatic hepatocellular carcinoma (HCC) cells. However, their functional roles in HCC cells remains unclear. Here, we investigated the biological ...

journal_title：Technology in cancer research & treatment

authors： Chen B,Zhou W,Tang C,Wang G,Yuan P,Zhang Y,Bhushan SC,Ma J,Leng J

更新日期：2020-01-01 00:00:00

abstract：:Optical mammography is one of several new techniques for breast cancer detection and characterization presently under development for clinical use that provide information other than morphologic, in particular on the biochemical and metabolic state of normal and diseased tissue. In breast tissue, scattering of red to ...

journal_title：Technology in cancer research & treatment

authors： Rinneberg H,Grosenick D,Moesta KT,Mucke J,Gebauer B,Stroszczynski C,Wabnitz H,Moeller M,Wassermann B,Schlag PM

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the efficacy and toxicity of robotic CyberKnife (Accuray Incorporated, Sunnyvale, California)-based stereotactic body radiation therapy (SBRT) in patients with recurrent or metastatic abdominopelvic tumors. METHODS AND MATERIALS:A total of 69 patients treated between Ma...

journal_title：Technology in cancer research & treatment

authors： Sezen D,Gurkaynak M,Gultekin M,Cengiz M,Yildiz F,Zorlu F,Akyol F,Yazici G,Hurmuz P,Ozyigit G

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Palliation of advanced disease using radiotherapy can create difficult clinical situations where standard computed tomography simulation and immobilization techniques are not feasible. We developed a linear accelerator-based radiotherapy simulation technique using nonstandard patient positioning for head and...

journal_title：Technology in cancer research & treatment

authors： Dyer BA,Nair CK,Deardorff CE,Wright CL,Perks JR,Rao SS

更新日期：2019-01-01 00:00:00

abstract：:Stereotactic body radiation therapy is a well-tolerated modality for the treatment of primary and metastatic liver lesions, and fiducials are often used as surrogates for tumor tracking during treatment. We evaluated respiratory-induced liver deformation by measuring the rigidity of the fiducial configuration during t...

journal_title：Technology in cancer research & treatment

authors： Paulsson AK,Yom SS,Anwar M,Pinnaduwage D,Sudhyadhom A,Gottschalk AR,Chang AJ,Descovich M

更新日期：2017-12-01 00:00:00

abstract：:eLiposomes encapsulate a perfluorocarbon nanoemulsion droplet inside a liposome. Ultrasound is then used as a trigger mechanism to vaporize the perfluorocarbon, break the liposome, and release the desired drug to the tumor tissue. The purpose of this research is to show that eLiposomes synthesized using perfluoropenta...

journal_title：Technology in cancer research & treatment

authors： Husseini GA,Pitt WG,Javadi M

更新日期：2015-08-01 00:00:00

abstract：:Our results indicate that the surface chemistry, composition, and 3-D structure of nanoparticles are critical in determining their in vivo biodistribution, and therefore the efficacy of nanodevice imaging and therapies. We demonstrate that gold/dendrimer nanocomposites in vivo, present biodistribution characteristics ...

journal_title：Technology in cancer research & treatment

authors： Khan MK,Nigavekar SS,Minc LD,Kariapper MS,Nair BM,Lesniak WG,Balogh LP

更新日期：2005-12-01 00:00:00

abstract：:This paper models steady state acoustic release of Doxorubicin (Dox) from Pluronic P105 micelles using Artificial Neural Networks (ANN). Previously collected release data were compiled and used to train, validate, and test an ANN model. Sensitivity analysis was then performed on the following operating conditions: ult...

journal_title：Technology in cancer research & treatment

authors： Husseini GA,Abdel-Jabbar NM,Mjalli FS,Pitt WG

更新日期：2007-02-01 00:00:00

abstract：:For most basic radiobiological research applications involving irradiation of small animals, it is difficult to achieve the same high precision dose distribution realized with human radiotherapy. The precision for irradiations performed with standard radiotherapy equipment is +/-2 mm in each dimension, and is adequate...

journal_title：Technology in cancer research & treatment

authors： DesRosiers C,Mendonca MS,Tyree C,Moskvin V,Bank M,Massaro L,Bigsby RM,Caperall-Grant A,Valluri S,Dynlacht JR,Timmerman R

更新日期：2003-10-01 00:00:00

abstract：:Despite remarkable progress in diagnosis and treatment, malignant glioma, a highly lethal cancer of the central nervous system, remains incurable. Although glioma stem-like cells (GSCs) represent a relatively small fraction of the cells in malignant glioma, they can proliferate and self renew extensively, being crucia...

journal_title：Technology in cancer research & treatment

authors： Xu ZY,Li XQ,Chen S,Cheng Y,Deng JM,Wang ZG

更新日期：2012-12-01 00:00:00