Glioma stem-like cells are less susceptible than glioma cells to sonodynamic therapy with photofrin.

abstract：:Endoscopic endonasal surgery (EES) has been shown to be a feasible approach to cranial base tumors while reducing post-operative morbidity. Using the endoscopic endonasal approach alone or in combination with open approaches may provide advantages over conventional approaches. However, the balance between maximal rese...

journal_title：Technology in cancer research & treatment

authors： Paravati AJ,Heron DE,Gardner PA,Snyderman C,Ozhasoglu C,Quinn A,Burton SA,Seelman K,Mintz AH

更新日期：2010-10-01 00:00:00

abstract：:Stereotactic body radiation therapy is a well-tolerated modality for the treatment of primary and metastatic liver lesions, and fiducials are often used as surrogates for tumor tracking during treatment. We evaluated respiratory-induced liver deformation by measuring the rigidity of the fiducial configuration during t...

journal_title：Technology in cancer research & treatment

authors： Paulsson AK,Yom SS,Anwar M,Pinnaduwage D,Sudhyadhom A,Gottschalk AR,Chang AJ,Descovich M

更新日期：2017-12-01 00:00:00

abstract：:Poorly differentiated cell populations including tumor-initiating stem cells have been demonstrated to display a unique ability to natively internalize fragmented double-stranded DNA. Using this feature as a marker, we show that 0.1% to 6% of human glioblastoma cells from the bioptates can effectively internalize a fl...

journal_title：Technology in cancer research & treatment

authors： Dolgova EV,Mishinov SV,Proskurina AS,Potter EA,Efremov YR,Bayborodin SI,Tyrinova TV,Stupak VV,Ostatin AA,Chernykh ER,Bogachev SS

更新日期：2018-01-01 00:00:00

abstract：:Brachytherapy has the advantage of delivering a high dose to the tumor while sparing the surrounding normal tissues. With proper case selection and delivery technique, high-dose-rate (HDR) brachytherapy has great promise, because it eliminates radiation exposure, allows short treatment times, and can be performed on a...

journal_title：Technology in cancer research & treatment

authors： Nag S

更新日期：2004-06-01 00:00:00

abstract：:The efficacy of photodynamic therapy for the treatment of a large number of skin diseases, in particular non-malignant skin cancer, has been reported by a number of studies. It has been demonstrated to be particularly beneficial for large or multiple lesions, especially where good cosmesis is required. However for PDT...

journal_title：Technology in cancer research & treatment

authors： Kendall CA,Morton CA

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:We aimed to identify the expression of Sal-like 4 (SALL4) in breast cancer tissues and to explore the role of this gene in the carcinogenesis of breast cancer cells. METHODS:A total of 62 paired breast cancer and noncancerous tissue samples were obtained from patients with breast cancer. SALL4 expression pat...

journal_title：Technology in cancer research & treatment

authors： Liu C,Yao F,Mao X,Li W,Chen H

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The incidence of colorectal cancer is increasing every year, and autophagy may be related closely to the pathogenesis of colorectal cancer. Autophagy is a natural catabolic mechanism that allows the degradation of cellular components in eukaryotic cells. However, autophagy plays a dual role in tumorigenesis. ...

journal_title：Technology in cancer research & treatment

authors： Liu TT,Liu SM

更新日期：2020-01-01 00:00:00

abstract：:Complement 3a (C3a) and complement 5a (C5a), small cleavage fragments generated by complement activation, has been previously shown to be obviously up-regulated in highly metastatic hepatocellular carcinoma (HCC) cells. However, their functional roles in HCC cells remains unclear. Here, we investigated the biological ...

journal_title：Technology in cancer research & treatment

authors： Chen B,Zhou W,Tang C,Wang G,Yuan P,Zhang Y,Bhushan SC,Ma J,Leng J

更新日期：2020-01-01 00:00:00

abstract：:Most experimental studies of electroporation focus on permeabilization of the outer cell membrane. Some experiments address delivery of ions and molecules into cells that should survive; others focus on efficient killing of the cells with minimal temperature rise. A basic method for quantifying electroporation effecti...

journal_title：Technology in cancer research & treatment

authors： Sweeney DC,Weaver JC,Davalos RV

更新日期：2018-01-01 00:00:00

abstract：:This paper models steady state acoustic release of Doxorubicin (Dox) from Pluronic P105 micelles using Artificial Neural Networks (ANN). Previously collected release data were compiled and used to train, validate, and test an ANN model. Sensitivity analysis was then performed on the following operating conditions: ult...

journal_title：Technology in cancer research & treatment

authors： Husseini GA,Abdel-Jabbar NM,Mjalli FS,Pitt WG

更新日期：2007-02-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) and Protein kinase B (PKB/Akt) play a crucial role in the formation of many malignant tumors and have been shown to be the important therapeutic targets. In the present study, we examined immunohistochemical expression of phosphorylated Akt (p-Akt) and COX-2 in 45 gastric adenocarcinomas with ...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Zhang QY,Fu YC,Wang T,Zhang J,Xu P,Zhou X,Pu PY,Kang CS

更新日期：2009-12-01 00:00:00

abstract：:Intensity-modulated radiation therapy (IMRT) has gained rapid and wide-spread acceptance in the radiation oncology community for its ability to create dose distributions that conform to the convoluted shapes of many tumors. It is a complicated treatment technique, for which quality assurance procedures are correspondi...

journal_title：Technology in cancer research & treatment

authors： Ibbott GS,Molineu A,Followill DS

更新日期：2006-10-01 00:00:00

abstract：:The objective of this study is to compare the new and conventional tomotherapy treatment techniques and to evaluate dosimetric differences between them. A dosimetric analysis was performed by comparing planning target volume (PTV) median dose, 95% of PTV dose coverage, Paddick conformity index (CI), homogeneity index ...

journal_title：Technology in cancer research & treatment

authors： Zhang X,Penagaricano J,Han EY,Morrill S,Hardee M,Liang X,Gupta SK,Corry PM,Ratanatharathom V

更新日期：2015-08-01 00:00:00

abstract：:The aim of this paper is to study the feasibility for determining the individual internal target volume (ITV) for hepatocellular carcinoma (HCC) using 3DCT associated with active breathing coordinator (ABC), comparing the ITVs defined by 3DCT associated with ABC and 4DCT. Thirteen patients with HCC after transarterial...

journal_title：Technology in cancer research & treatment

authors： Gong G,Yin Y,Xing L,Guo Y,Chen J,Liu T,Lu J,Ma C,Sun T,Bai T,Zhang G,Deng W

更新日期：2011-12-01 00:00:00

abstract：:The inhibitor of growth (ING) family proteins have been defined as candidate tumor suppressors. ING4 as a novel member of ING family has potential tumor-suppressive effects via multiple pathways. However, the therapeutic effect of adenovirus-mediated ING4 (Ad-ING4) gene transfer in human osteosarcoma is still unknown....

journal_title：Technology in cancer research & treatment

authors： Xu M,Xie Y,Sheng W,Miao J,Yang J

更新日期：2015-10-01 00:00:00

abstract：:Colorectal cancer is one of the most common cancers in the world. Protein phosphatase magnesium-dependent 1 d (PPM1D) is aberrantly upregulated in many human carcinoma cells, and recent research has suggested that it could be a potential therapeutic target of cancer. However, the function of PPM1D in colorectal carcin...

journal_title：Technology in cancer research & treatment

authors： Yin H,Yan Z,Liang Y,Liu B,Su Q

更新日期：2013-12-01 00:00:00

abstract：:Results for treating glomus jugulare tumors with radiosurgery have been limited by short follow-up and small number of patients. We report our experience using LINAC or CyberKnife in 21 tumors with a median follow-up of 66 months (Mean follow-up of 60 months). In addition, we have a subset of eight patients that were ...

journal_title：Technology in cancer research & treatment

authors： Lim M,Bower R,Nangiana JS,Adler JR,Chang SD

更新日期：2007-10-01 00:00:00

abstract：:Hepatocellular carcinoma is the fourth leading cause of cancer-related death worldwide. Depending on the extent of disease and competing comorbidities for mortality, multiple liver-directed therapy options exist for the treatment of hepatocellular carcinoma. Advancements in radiation oncology have led to the emergence...

journal_title：Technology in cancer research & treatment

authors： Schaub SK,Hartvigson PE,Lock MI,Høyer M,Brunner TB,Cardenes HR,Dawson LA,Kim EY,Mayr NA,Lo SS,Apisarnthanarax S

更新日期：2018-01-01 00:00:00

abstract：:Since "Warburg effect" has been firstly uncovered in cancer cells in 1956, mounting evidence has supported the molecular mechanism underlying the energy metabolism in induced chemoresistance in cancers. MicroRNAs can mediate fine-tuning of genes in physiological process. MicroRNAs' energy metabolic role in chemoresist...

journal_title：Technology in cancer research & treatment

authors： Ye J,Zou M,Li P,Liu H

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:The efficacy of image-guided high-dose rate brachytherapy for cervical cancer is limited by the ineffective rectal sparing devices available commercially and the potential applicator movement. We developed a novel device using a balloon catheter and a belt immobilization system, serving for rectal dose reductio...

journal_title：Technology in cancer research & treatment

authors： Fan Q,Yeung AR,Amdur R,Helmig R,Park J,Li J,Kahler D,Liu C,Lu B

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Acute myeloid leukemia (AML) represents a hematological cancer. The aim of the investigation was to probe the regulatory relevance of long non-coding RNA (lncRNA) aspartyl-tRNA synthetase anti-sense 1 (DARS-AS1)/microRNA-425 (miR-425)/transforming growth factor-beta 1 (TGFB1) to the development of AML. METHO...

journal_title：Technology in cancer research & treatment

authors： Dou B,Jiang Z,Chen X,Wang C,Wu J,An J,Sheng G

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To assess the efficacy of stereotactic body radiotherapy in patients with unresectable locally advanced pancreatic cancer. MATERIALS AND METHODS:All patients received a prescription dose of 45 Gy in 6 fractions. Primary end point was freedom from local progression. Secondary end points were overall survival, p...

journal_title：Technology in cancer research & treatment

authors： Comito T,Cozzi L,Clerici E,Franzese C,Tozzi A,Iftode C,Navarria P,D'Agostino G,Rimassa L,Carnaghi C,Personeni N,Tronconi MC,De Rose F,Franceschini D,Ascolese AM,Fogliata A,Tomatis S,Santoro A,Zerbi A,Scorsetti M

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the mechanisms involved with miRNA-708 and its targeting of bone morphogenetic protein and activin membrane-bound inhibitor in cell proliferation, migration, and apoptosis in mice with melanoma via the Wnt and transforming growth factor β signaling pathways. METHODS:Sixt...

journal_title：Technology in cancer research & treatment

authors： Lu HJ,Yan J,Jin PY,Zheng GH,Zhang HL,Bai M,Wu DM,Lu J,Zheng YL

更新日期：2018-01-01 00:00:00

abstract：:Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...

journal_title：Technology in cancer research & treatment

authors： ten Hagen TL,Eggermont AM

更新日期：2003-06-01 00:00:00

abstract：:Fascin is overexpressed in various tumor tissues and is closely related to tumor metastasis and invasion. However, the role of fascin in cholangiocarcinoma RBE cells has not been clearly reported. This study aimed to establish a cholangiocarcinoma cell line with stable and high expression of fascin to observe the effe...

journal_title：Technology in cancer research & treatment

authors： Zhao H,Yang F,Zhao W,Zhang C,Liu J

更新日期：2016-04-01 00:00:00

abstract：:Chemo-radiotherapy is standard treatment of stage IIIA-N2 bulky or IIIB non-small cell lung cancer (NSCLC). Surgical resection of residual disease in downstaged patients may improve overall survival. In this setting, restaging disease is still a challenge. 18F-FDG PET/CT represents the gold standard although accuracy ...

journal_title：Technology in cancer research & treatment

authors： Genestreti G,Burgio MA,Matteucci F,Piciucchi S,Scarpi E,Monti M,Bucchi L,Parisi E,Crociani L,Gurioli C,Poletti V,Gavelli G

更新日期：2015-12-01 00:00:00

abstract：:We have constructed a multimodal contrast agent suitable for near-infrared, NIR, fluorescent imaging as well as magnetic resonance imaging, MRI. This class of agents may be useful for preoperative tumor localization and tumor functional evaluation and for intraoperative delineation of tumor margins. We have covalently...

journal_title：Technology in cancer research & treatment

authors： Uzgiris EE,Sood A,Bove K,Grimmond B,Lee D,Lomnes S

更新日期：2006-08-01 00:00:00

abstract：:Ionizing radiation therapy is one of the primary modalities for treating cancers. Ideally, the particle selected to deliver ionizing radiation for routine therapy should control the disease, cause minimal side effects, and be affordable. Two major properties for judging the utility of a particle, physical controllabil...

journal_title：Technology in cancer research & treatment

authors： Slater JM

更新日期：2007-08-01 00:00:00

abstract：:This study was designed to estimate the risk of radiation-associated tumors and clinical toxicity in the brain following fractionated radiation treatment of pituitary adenoma. A standard case of a patient with a pituitary adenoma was planned using 8 different dosimetric techniques. Total dose was 50.4 Gy (GyE) at dail...

journal_title：Technology in cancer research & treatment

authors： Winkfield KM,Niemierko A,Bussiere MR,Crowley EM,Napolitano BN,Beaudette KP,Loeffler JS,Shih HA

更新日期：2011-06-01 00:00:00

abstract：:This review addresses the epidemiology, historical reports, current issues, data and controversies involved in the management of brain metastases. The literature regarding surgery, whole brain radiation therapy, stereotactic radiosurgery or some combination of those treatments is discussed as well as issues of cost-ef...

journal_title：Technology in cancer research & treatment

authors： Sperduto PW

更新日期：2003-04-01 00:00:00