Sensitization of Radiation or Gemcitabine-Based Chemoradiation Therapeutic Effect by Nimotuzumab in Pancreatic Cancer Cells.

abstract：:Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...

journal_title：Technology in cancer research & treatment

authors： ten Hagen TL,Eggermont AM

更新日期：2003-06-01 00:00:00

abstract：:Proteomics is a rapidly expanding discipline that aims to gain a comprehensive understanding of the expressions, modification, interactions, and regulation of proteins in cells. New high-throughput technologies, such as protein chips and isotope-coded affinity tag peptide labeling, coupled with classic technologies su...

journal_title：Technology in cancer research & treatment

authors： Choi W,Song SW,Zhang W

更新日期：2002-08-01 00:00:00

abstract：:As one of the common cancers that threaten human life, the recurrence and metastasis of colorectal cancer seriously affect the prognosis of patients. Although new drugs and comprehensive treatments have been adopted, the current treatment effect on this tumor, especially in advanced colorectal cancer, is still not sat...

journal_title：Technology in cancer research & treatment

authors： Ma YS,Li W,Liu Y,Shi Y,Lin QL,Fu D

更新日期：2020-01-01 00:00:00

abstract：:Despite remarkable progress in diagnosis and treatment, malignant glioma, a highly lethal cancer of the central nervous system, remains incurable. Although glioma stem-like cells (GSCs) represent a relatively small fraction of the cells in malignant glioma, they can proliferate and self renew extensively, being crucia...

journal_title：Technology in cancer research & treatment

authors： Xu ZY,Li XQ,Chen S,Cheng Y,Deng JM,Wang ZG

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Osteosarcoma is a common malignant bone tumor that is frequently found in the long bones of children and adolescents. The aim of this study is to examine long noncoding RNA-steroid receptor RNA activator 1 expression in osteosarcoma to explore the biological function of long noncoding RNA steroid receptor RNA...

journal_title：Technology in cancer research & treatment

authors： Guo W,Jiang H,Li H,Li F,Yu Q,Liu Y,Jiang W,Zhang M

更新日期：2019-01-01 00:00:00

abstract：:This study aimed to analysis outcome and prognosis of interstitial 125I seed implantation in patients with cervical lymph node recurrence after multimodal treatment of thoracic esophageal squamous cell carcinoma (ESCC). We conducted a retrospective review of 19 patients with 32 cervical lymph nodes recurrences after m...

journal_title：Technology in cancer research & treatment

authors： Lin L,Wang J,Jiang Y,Meng N,Tian S,Yang R,Ran W,Liu C

更新日期：2015-04-01 00:00:00

abstract：:The coupling mechanism between neuronal firing and cerebrovascular dilatation can be significantly compromised in cerebral diseases, making it difficult to identify eloquent cortical areas near or within resectable lesions by using Blood Oxygen Level Dependent (BOLD) fMRI. Several metabolic and vascular factors have ...

journal_title：Technology in cancer research & treatment

authors： Pillai JJ,Zacà D

更新日期：2012-08-01 00:00:00

abstract：:The integrated use of optical technologies for patient monitoring is addressed in the framework of time-resolved treatment delivery for scanned ion beam therapy. A software application has been designed to provide the therapy control system (TCS) with a continuous geometrical feedback by processing the external surrog...

journal_title：Technology in cancer research & treatment

authors： Fattori G,Saito N,Seregni M,Kaderka R,Pella A,Constantinescu A,Riboldi M,Steidl P,Cerveri P,Bert C,Durante M,Baroni G

更新日期：2014-12-01 00:00:00

abstract：:Planning robotic radiosurgery treatments for multiple (n > 3) metastatic brain lesions is challenging due to the need of satisfying a large number of dose-volume constraints and the requirement of prescribing different dose levels to individual targets. In this study, we developed a sequential two-step optimization te...

journal_title：Technology in cancer research & treatment

authors： Ma L,Sahgal A,Hwang A,Hu W,Descovich M,Chuang C,Barani I,Sneed PK,McDermott M,Larson DA

更新日期：2011-08-01 00:00:00

abstract：:Brachytherapy has the advantage of delivering a high dose to the tumor while sparing the surrounding normal tissues. With proper case selection and delivery technique, high-dose-rate (HDR) brachytherapy has great promise, because it eliminates radiation exposure, allows short treatment times, and can be performed on a...

journal_title：Technology in cancer research & treatment

authors： Nag S

更新日期：2004-06-01 00:00:00

abstract：:This article proposes quantitative analysis tools and digital phantoms to quantify intrinsic errors of deformable image registration (DIR) systems and establish quality assurance (QA) procedures for clinical use of DIR systems utilizing local and global error analysis methods with clinically realistic digital image ph...

journal_title：Technology in cancer research & treatment

authors： Kim H,Park SB,Monroe JI,Traughber BJ,Zheng Y,Lo SS,Yao M,Mansur D,Ellis R,Machtay M,Sohn JW

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. MATERIALS AND METHODS:A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identi...

journal_title：Technology in cancer research & treatment

authors： Korpics M,Johnson P,Patel R,Surucu M,Choi M,Emami B,Roeske JC

更新日期：2016-12-01 00:00:00

abstract：:A specific protein profile that accompanies neoplastic transformation in the premalignant airway epithelium could provide an opportunity for early diagnosis of lung cancer. The aim of this study was to screen and identify early candidate biomarkers of non-small cell lung cancer. Thirteen non-small cell lung cancer sam...

journal_title：Technology in cancer research & treatment

authors： Nan Y,Du J,Ma L,Jiang H,Jin F,Yang S

更新日期：2017-02-01 00:00:00

abstract：:Numerous beam directions using 3-D conformal techniques can be employed in treating tumors in the posterior fossa, each with characteristic normal tissue exposure along the entrance and exit trajectory. A representative variety of beam configurations were modeled in a modern computer planning system initially with the...

journal_title：Technology in cancer research & treatment

authors： Timmerman RD,Ewing M,Donges M,Wilson J,Jakacki R,Randall ME

更新日期：2003-12-01 00:00:00

abstract：:Hydroxycamptothecin-encapsulated chitosan (HC) nanospheres were prepared by Shirasu porous glass (SPG) membrane emulsification technique. The properties and morphology of HC nanospheres were characterized. The diameter of the nanospheres could be controlled within a narrow distribution according to the pore-size of SP...

journal_title：Technology in cancer research & treatment

authors： Han J,Hou ZQ,Wang YG,Guo X

更新日期：2015-02-01 00:00:00

abstract：:Positron emission tomography (PET), the imaging of pharmaceuticals labeled with positron-emitting radionuclides, is a rapidly growing modality for the diagnosis and management of cancer. PET yields high-quality images characterizing substrate metabolism, cellular proliferation, receptor density, and other parameters t...

journal_title：Technology in cancer research & treatment

authors： Mandelkern M,Raines J

更新日期：2002-12-01 00:00:00

abstract：:Targeted immunotherapy using dendritic cell vaccine has been employed for the treatment of solid tumors. Topical 5-aminolevulinic acid-mediated photodynamic therapy, an established approach for topical cancers, can induce an effective antitumor immune response. We have previously shown that 5-aminolevulinic acid-media...

journal_title：Technology in cancer research & treatment

authors： Zhang H,Wang P,Wang X,Shi L,Fan Z,Zhang G,Yang D,Bahavar CF,Zhou F,Chen WR,Wang X

更新日期：2018-01-01 00:00:00

abstract：:This review addresses the epidemiology, historical reports, current issues, data and controversies involved in the management of brain metastases. The literature regarding surgery, whole brain radiation therapy, stereotactic radiosurgery or some combination of those treatments is discussed as well as issues of cost-ef...

journal_title：Technology in cancer research & treatment

authors： Sperduto PW

更新日期：2003-04-01 00:00:00

abstract：:In order to identify the proteomic differences between renal cell carcinoma (RCC) and benign renal tumors, we analyzed 168 serum samples from 65 RCC patients, 34 patients with benign renal tumors, and 69 healthy persons using the IMAC-Cu2+ ProteinChip system by surface enhanced laser desorption/ionization mass spectro...

journal_title：Technology in cancer research & treatment

authors： Xu G,Xiang CQ,Lu Y,Wang WJ,Kang XN,Liao P,Ding Q,Zhang YF

更新日期：2009-06-01 00:00:00

abstract：:Non-thermal irreversible electroporation (N-TIRE) has shown promise as an ablative therapy for a variety of soft-tissue neoplasms. Here we describe the therapeutic planning aspects and first clinical application of N-TIRE for the treatment of an inoperable, spontaneous malignant intracranial glioma in a canine patient...

journal_title：Technology in cancer research & treatment

authors： Garcia PA,Pancotto T,Rossmeisl JH Jr,Henao-Guerrero N,Gustafson NR,Daniel GB,Robertson JL,Ellis TL,Davalos RV

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Acute myeloid leukemia (AML) represents a hematological cancer. The aim of the investigation was to probe the regulatory relevance of long non-coding RNA (lncRNA) aspartyl-tRNA synthetase anti-sense 1 (DARS-AS1)/microRNA-425 (miR-425)/transforming growth factor-beta 1 (TGFB1) to the development of AML. METHO...

journal_title：Technology in cancer research & treatment

authors： Dou B,Jiang Z,Chen X,Wang C,Wu J,An J,Sheng G

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate long-term outcomes and prognostic factors of laparoscopic microwave ablation as a first-line treatment for hepatocellular carcinoma located at the liver surface not feasible for percutaneous ablation. METHODS:51 consecutive patients receiving laparoscopic microwave ablation in our cente...

journal_title：Technology in cancer research & treatment

authors： Wang T,Zhang XY,Lu X,Zhai B

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To assess the efficacy of stereotactic body radiotherapy in patients with unresectable locally advanced pancreatic cancer. MATERIALS AND METHODS:All patients received a prescription dose of 45 Gy in 6 fractions. Primary end point was freedom from local progression. Secondary end points were overall survival, p...

journal_title：Technology in cancer research & treatment

authors： Comito T,Cozzi L,Clerici E,Franzese C,Tozzi A,Iftode C,Navarria P,D'Agostino G,Rimassa L,Carnaghi C,Personeni N,Tronconi MC,De Rose F,Franceschini D,Ascolese AM,Fogliata A,Tomatis S,Santoro A,Zerbi A,Scorsetti M

更新日期：2017-06-01 00:00:00

abstract：:We investigated the technique, early results and toxicity of curative stereotactic radiotherapy with the CyberKnife (Accuray Incorporated, Sunnyvale, California, USA) in 15 extracranial, extrapulmonary, extrahepatic, and extraspinal tumors. Fourteen tumors were located close to the bowel or esophagus. The PTV = GTV + ...

journal_title：Technology in cancer research & treatment

authors： Nuyttens JJ,Prevost JB,Van der Voort van Zijp NC,Hoogeman M,Levendag PC

更新日期：2007-12-01 00:00:00

abstract：:Electrochemotherapy is an effective antitumor treatment employing locally applied high voltage electric pulses delivered through conductive electrodes to the tumor in combination with chemotherapeutic drugs. The efficiency of electrochemotherapy strongly depends on the local electric field distribution inside the targ...

journal_title：Technology in cancer research & treatment

authors： Corovic S,Al Sakere B,Haddad V,Miklavcic D,Mir LM

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND AIM:Methylated SEPT9 is a novel circulating tumor DNA marker for colorectal cancer, while the effects of various colorectal cancer clinicopathological factors on its detection performance have not been fully evaluated. This study aims to investigate the significance of the clinicopathological factors on ...

journal_title：Technology in cancer research & treatment

authors： He N,Song L,Kang Q,Jin P,Cai G,Zhou J,Zhou G,Sheng J,Cai S,Wang J,Han X,Nie Y,Wu K

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To investigate the role of intensity-modulated proton therapy (IMPT) for hepatocellular carcinoma (HCC) patients to be treated with stereotactic body radiation therapy (SBRT) in a risk-adapted dose prescription regimen. METHODS:A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escala...

journal_title：Technology in cancer research & treatment

authors： Cozzi L,Comito T,Loi M,Fogliata A,Franzese C,Franceschini D,Clerici E,Reggiori G,Tomatis S,Scorsetti M

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Neoadjuvant chemoradiotherapy (nCRT) followed by operation has become the standard treatment for locally advanced rectal cancer (LARC). However, considering the possible toxicity and complications of radiochemotherapy, nCRT is seldom used for the elderly. The purpose of this study was to assess the safety ...

journal_title：Technology in cancer research & treatment

authors： Liu H,Li C,Zhao Z,Guan X,Yang M,Liu Z,Tang Y,Jiang Z,Wang X

更新日期：2020-01-01 00:00:00

abstract：:Tumstatin (Tum) is a powerful angiostatin that inhibits proliferation and induces apoptosis of tumorous vascular endothelial cells. A nonpathogenic and anaerobic bacterium, Bifidobacterium longum (BL), selectively localizes to and proliferates in the hypoxia location within solid tumor. The aims of this study were to ...

journal_title：Technology in cancer research & treatment

authors： Wei C,Xun AY,Wei XX,Yao J,Wang JY,Shi RY,Yang GH,Li YX,Xu ZL,Lai MG,Zhang R,Wang LS,Zeng WS

更新日期：2016-06-01 00:00:00

abstract：:The ultrasound-guided diffuse optical tomography is a noninvasive imaging technique for breast cancer diagnosis and treatment monitoring. The technique uses a handheld probe capable of providing measurements of multiple wavelengths in a few seconds. These measurements are used to estimate optical absorptions of lesion...

journal_title：Technology in cancer research & treatment

authors： Althobaiti M,Vavadi H,Zhu Q

更新日期：2018-01-01 00:00:00