Commissioning of an integrated platform for time-resolved treatment delivery in scanned ion beam therapy by means of optical motion monitoring.

abstract：:Despite remarkable progress in diagnosis and treatment, malignant glioma, a highly lethal cancer of the central nervous system, remains incurable. Although glioma stem-like cells (GSCs) represent a relatively small fraction of the cells in malignant glioma, they can proliferate and self renew extensively, being crucia...

journal_title：Technology in cancer research & treatment

authors： Xu ZY,Li XQ,Chen S,Cheng Y,Deng JM,Wang ZG

更新日期：2012-12-01 00:00:00

abstract：:Poorly differentiated cell populations including tumor-initiating stem cells have been demonstrated to display a unique ability to natively internalize fragmented double-stranded DNA. Using this feature as a marker, we show that 0.1% to 6% of human glioblastoma cells from the bioptates can effectively internalize a fl...

journal_title：Technology in cancer research & treatment

authors： Dolgova EV,Mishinov SV,Proskurina AS,Potter EA,Efremov YR,Bayborodin SI,Tyrinova TV,Stupak VV,Ostatin AA,Chernykh ER,Bogachev SS

更新日期：2018-01-01 00:00:00

abstract：:This study aims to reduce the uncertainty about the photoneutron dose produced over a course of radiotherapy with high-energy photon beams and evaluate photoneutron contamination-based secondary malignancy risk for different treatment modalities. Dosimetric measurements were taken in Philips SL25/75, Elekta Synergy Pl...

journal_title：Technology in cancer research & treatment

authors： Biltekin F,Yeginer M,Ozyigit G

更新日期：2016-08-01 00:00:00

abstract：:The combined effect of high energy shock waves (HESW), generated by a piezoelectric device, and paclitaxel on Mat B-III rat breast cancer cells in vitro and in an in vivo animal model is presented. A significant reduction of in vitro Mat B-III cell proliferation versus cells treated with paclitaxel alone was observed ...

journal_title：Technology in cancer research & treatment

authors： Canaparo R,Serpe L,Zara GP,Chiarle R,Berta L,Frairia R

更新日期：2008-04-01 00:00:00

abstract：:The microRNA-200 (miR-200) family has been reported to be vital for the inhibition of epithelial-to-mesenchymal transition (EMT) in tumor cells. The miR-200 family represents a complex multi-factorial regulatory network which has not been well described in breast cancer. This study aimed to clarify the underlying regu...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Shao N,Yang X,Xie C,Shi Y,Lin Y

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. MATERIALS AND METHODS:A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identi...

journal_title：Technology in cancer research & treatment

authors： Korpics M,Johnson P,Patel R,Surucu M,Choi M,Emami B,Roeske JC

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:In this study, we aimed to evaluate the prognostic value of fluorodeoxyglucose uptake in the lung parenchyma and the presence of subclinical interstitial lung disease on computed tomography as predictive factors for survival following stereotactic body radiation therapy in patients with stage I non-small cell l...

journal_title：Technology in cancer research & treatment

authors： Satoh Y,Motosugi U,Saito A,Omiya Y,Onishi H

更新日期：2018-01-01 00:00:00

abstract：:Although an MRI scanner is a single stand-alone modality, different acquisition techniques may be applied to collect structural and functional information, including vascular or angiogenic properties measured by dynamic contrast enhanced MRI (DCE-MRI) and Choline (Cho) metabolism measured by proton MR spectroscopy ima...

journal_title：Technology in cancer research & treatment

authors： Su MY,Baik HM,Yu HJ,Chen JH,Mehta RS,Nalcioglu O

更新日期：2006-08-01 00:00:00

abstract：:Optical methods such as reflectance and fluorescence spectroscopy are being investigated for their potential to aid cancer detection in a quantitative, minimally invasive manner. Mathematical models of reflectance and fluorescence provide an important link between measured optical data and biomedically-relevant tissue...

journal_title：Technology in cancer research & treatment

authors： Wilson RH,Mycek MA

更新日期：2011-04-01 00:00:00

abstract：:We do not know the clinical and prognostic factors that influence the survival of patients with gastric signet ring cell carcinoma (SRC). Therefore, a retrospective review was undertaken of 219 patients with SRC who had undergone gastrectomy between January 2009 and December 2012 in our hospital. Patient age, sex, TNM...

journal_title：Technology in cancer research & treatment

authors： Yu JM,Zhan ZW,Zhen JX,Wang XJ,Chen Y,Lin J,Chen L,Chen LZ,Huang YF,Guo ZQ

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The biological function of deoxycytidine kinase in tumor is not yet clear, and there are a few studies relating to the correlation of deoxycytidine kinase gene with the occurrence and development of liver cancer. METHODS:The messenger RNA expression of deoxycytidine kinase was analyzed with the use of the U...

journal_title：Technology in cancer research & treatment

authors： Hu SF,Lin X,Xu LP,Chen HG,Guo JF,Jin L

更新日期：2020-01-01 00:00:00

abstract：AIM:To explore the relationship of clinicopathological features and the proteins of C-met expression in the prognosis of cholangiocarcinoma. METHODS:Clinical data and the completed follow-up information of patients with cholangiocarcinoma who underwent cholangiocarcinoma operation from January 2004 to December 2010 we...

journal_title：Technology in cancer research & treatment

authors： Mao ZY,Zhu GQ,Ren L,Guo XC,Su D,Bai L

更新日期：2016-04-01 00:00:00

abstract：:The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C(60)(OH)(24) in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Experiment was performed on adult female Spra...

journal_title：Technology in cancer research & treatment

authors： Injac R,Perse M,Boskovic M,Djordjevic-Milic V,Djordjevic A,Hvala A,Cerar A,Strukelj B

更新日期：2008-02-01 00:00:00

abstract：:This study quantifies the setup uncertainties to optimize the planning target volume (PTV) margin based on daily image guidance, its dosimetric impact, and radiobiological implication for intensity-modulated radiation therapy (IMRT) in head and neck cancer. Ten patients were retrospectively chosen who had been treated...

journal_title：Technology in cancer research & treatment

authors： Srivastava SP,Cheng CW,Das IJ

更新日期：2016-02-01 00:00:00

abstract：:For most basic radiobiological research applications involving irradiation of small animals, it is difficult to achieve the same high precision dose distribution realized with human radiotherapy. The precision for irradiations performed with standard radiotherapy equipment is +/-2 mm in each dimension, and is adequate...

journal_title：Technology in cancer research & treatment

authors： DesRosiers C,Mendonca MS,Tyree C,Moskvin V,Bank M,Massaro L,Bigsby RM,Caperall-Grant A,Valluri S,Dynlacht JR,Timmerman R

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:There is mounting evidence that microRNAs play an important role in nasopharyngeal carcinoma, which is widely prevalent in South China and is the most prevalent metastatic cancer among head and neck cancers. Recently, it has been shown that miR-494 is involved in the progression and prognosis of nasopharynge...

journal_title：Technology in cancer research & treatment

authors： He H,Liao X,Yang Q,Liu Y,Peng Y,Zhong H,Yang J,Zhang H,Yu Z,Zuo Y,Guan C,Xu Z

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Nonthermal irreversible electroporation is a minimally invasive surgery technology that employs high and brief electric fields to ablate undesirable tissues. Nonthermal irreversible electroporation can ablate only cells while preserving intact functional properties of the extracellular structures. Therefore,...

journal_title：Technology in cancer research & treatment

authors： Lv Y,Zhang Y,Huang J,Wang Y,Rubinsky B

更新日期：2019-01-01 00:00:00

abstract：:Hydroxycamptothecin-encapsulated chitosan (HC) nanospheres were prepared by Shirasu porous glass (SPG) membrane emulsification technique. The properties and morphology of HC nanospheres were characterized. The diameter of the nanospheres could be controlled within a narrow distribution according to the pore-size of SP...

journal_title：Technology in cancer research & treatment

authors： Han J,Hou ZQ,Wang YG,Guo X

更新日期：2015-02-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most aggressive type of gastrointestinal tumor, with a high rate of mortality. However, identifying biomarkers for the treatment of HCC remains to be developed. We aimed to determine whether cell division cycle 25C (CDC25C) could be used as a novel diagnostic and therapeutic bioma...

journal_title：Technology in cancer research & treatment

authors： Xun R,Lu H,Wang X

更新日期：2020-01-01 00:00:00

abstract：:Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is able to detect breast cancer with high sensitivity. Furthermore, this method provides functional information on tissue composition and vascularization. This study aims to identify the potential of DCE-MRI to predict distant metastasis in breast cancer p...

journal_title：Technology in cancer research & treatment

authors： Baltzer PA,Zoubi R,Burmeister HP,Gajda M,Camara O,Kaiser WA,Dietzel M

更新日期：2012-12-01 00:00:00

abstract：:This study was designed to estimate the risk of radiation-associated tumors and clinical toxicity in the brain following fractionated radiation treatment of pituitary adenoma. A standard case of a patient with a pituitary adenoma was planned using 8 different dosimetric techniques. Total dose was 50.4 Gy (GyE) at dail...

journal_title：Technology in cancer research & treatment

authors： Winkfield KM,Niemierko A,Bussiere MR,Crowley EM,Napolitano BN,Beaudette KP,Loeffler JS,Shih HA

更新日期：2011-06-01 00:00:00

abstract：:Brachytherapy has the advantage of delivering a high dose to the tumor while sparing the surrounding normal tissues. With proper case selection and delivery technique, high-dose-rate (HDR) brachytherapy has great promise, because it eliminates radiation exposure, allows short treatment times, and can be performed on a...

journal_title：Technology in cancer research & treatment

authors： Nag S

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Testicular cancer represents the most common malignancy in young adult men. In the current study, we sought to analyze and compare the prognostic value of lymph node ratio (LNR) as well as positive lymph node counts (LNC) to understand its clinical significance in testicular germ cell tumors. METHODS:We emp...

journal_title：Technology in cancer research & treatment

authors： Huang C,Long Q,Pan Y,Wu L,Wang X,Xu H,Zheng F

更新日期：2021-01-01 00:00:00

abstract：:Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...

journal_title：Technology in cancer research & treatment

authors： ten Hagen TL,Eggermont AM

更新日期：2003-06-01 00:00:00

abstract：:The objective of this study is to compare the new and conventional tomotherapy treatment techniques and to evaluate dosimetric differences between them. A dosimetric analysis was performed by comparing planning target volume (PTV) median dose, 95% of PTV dose coverage, Paddick conformity index (CI), homogeneity index ...

journal_title：Technology in cancer research & treatment

authors： Zhang X,Penagaricano J,Han EY,Morrill S,Hardee M,Liang X,Gupta SK,Corry PM,Ratanatharathom V

更新日期：2015-08-01 00:00:00

abstract：:We previously showed that microRNA-182 (miR-182) might promote cell proliferation and migration in triple-negative breast cancer (TNBC). This study aimed to investigate circular RNAs (circRNAs) that interact with miR-182 and play important roles in TNBC. Thirty patients with TNBC were enrolled. One pair of tumor and a...

journal_title：Technology in cancer research & treatment

authors： Yu J,Shen W,Xu J,Gong B,Gao B,Zhu J

更新日期：2020-01-01 00:00:00

abstract：:Tumor-infiltrating immune cells are part of a complex microenvironment and associated with improved clinical outcomes in a broad range of tumor types. However, a detailed map for the prognostic landscape of tumor-infiltrating immune cells and immune checkpoint modulators in glioblastoma is still lacking. Here, with th...

journal_title：Technology in cancer research & treatment

authors： Wu S,Yang W,Zhang H,Ren Y,Fang Z,Yuan C,Yao Z

更新日期：2019-01-01 00:00:00

abstract：:Helical tomotherapy is a form of image-guided intensity-modulated radiotherapy that introduces the ring gantry concept into radiation oncology. The system is a combination of a therapeutic linear accelerator and a megavoltage CT-scanner. This work describes the clinical experience with megavoltage CT with 456 patients...

journal_title：Technology in cancer research & treatment

authors： Sterzing F,Kalz J,Sroka-Perez G,Schubert K,Bischof M,Roder F,Debus J,Herfarth K

更新日期：2009-10-01 00:00:00

abstract：:The study of the effectiveness of cryotherapy as a curative treatment for prostate cancer has often relied on the use of either in vitro cell culture monolayers or animal models. While the data gleaned from these studies have been valuable, each model has inherent limitations. In order to bridge the gap between in vit...

journal_title：Technology in cancer research & treatment

authors： Robilotto AT,Clarke D,Baust JM,Van Buskirk RG,Gage AA,Baust JG

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:The aim of the in vivo dosimetry, during the fractionated radiation therapy, is the verification of the correct dose delivery to patient. Nowadays, in vivo dosimetry procedures for photon beams are based on the use of the electronic portal imaging device and dedicated software to elaborate electronic portal ima...

journal_title：Technology in cancer research & treatment

authors： Falco MD,Giancaterino S,De Nicola A,Adorante N,De Lorenzo RG,Di Tommaso M,Vinciguerra A,Trignani M,Perrotti F,Allajbej A,Fidanzio A,Greco F,Grusio M,Genovesi D,Piermattei A

更新日期：2018-01-01 00:00:00