abstract：:Human epidermal growth factor 2 (HER2)+ breast cancer is considered the most dangerous type of breast cancers. Herein, we used bioinformatics methods to identify potential key genes in HER2+ breast cancer to enable its diagnosis, treatment, and prognosis prediction. Datasets of HER2+ breast cancer and normal tissue sa...

journal_title：Technology in cancer research & treatment

authors： Weng Y,Liang W,Ji Y,Li Z,Jia R,Liang Y,Ning P,Xu Y

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:We compared radiotherapy plans among helical tomotherapy (HT), volumetric-modulated arc therapy (VMAT), and intensity-modulated proton therapy (IMPT) for angiosarcoma of the scalp (AS). METHODS:We conducted a planning study for 19 patients with AS. The clinical target volume (CTV) 1 and CTV2 were defined as ...

journal_title：Technology in cancer research & treatment

authors： Mizuno T,Tomita N,Takaoka T,Tomida M,Fukuma H,Tsuchiya T,Shibamoto Y

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Testicular cancer represents the most common malignancy in young adult men. In the current study, we sought to analyze and compare the prognostic value of lymph node ratio (LNR) as well as positive lymph node counts (LNC) to understand its clinical significance in testicular germ cell tumors. METHODS:We emp...

journal_title：Technology in cancer research & treatment

authors： Huang C,Long Q,Pan Y,Wu L,Wang X,Xu H,Zheng F

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Circulating tumor cells (CTCs) hold huge potential for both clinical applications and basic research into the management of cancer, but the relationship between CTC count and cervical cancer prognosis remains unclear. Therefore, research on this topic is urgently required. OBJECTIVE:This study investigated ...

journal_title：Technology in cancer research & treatment

authors： Du K,Huang Q,Bu J,Zhou J,Huang Z,Li J

更新日期：2020-01-01 00:00:00

abstract：:The microRNA-200 (miR-200) family has been reported to be vital for the inhibition of epithelial-to-mesenchymal transition (EMT) in tumor cells. The miR-200 family represents a complex multi-factorial regulatory network which has not been well described in breast cancer. This study aimed to clarify the underlying regu...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Shao N,Yang X,Xie C,Shi Y,Lin Y

更新日期：2020-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most aggressive type of gastrointestinal tumor, with a high rate of mortality. However, identifying biomarkers for the treatment of HCC remains to be developed. We aimed to determine whether cell division cycle 25C (CDC25C) could be used as a novel diagnostic and therapeutic bioma...

journal_title：Technology in cancer research & treatment

authors： Xun R,Lu H,Wang X

更新日期：2020-01-01 00:00:00

abstract：:Spinal metastases are a common manifestation of malignant tumors that can cause severe pain, spinal cord compression, pathological fractures, and hypercalcemia, and these clinical manifestations will ultimately reduce the health-related quality of life and even shorten life expectancy in patient with cancer. Effective...

journal_title：Technology in cancer research & treatment

authors： Zhang HR,Li JK,Yang XG,Qiao RQ,Hu YC

更新日期：2020-01-01 00:00:00

abstract：:We do not know the clinical and prognostic factors that influence the survival of patients with gastric signet ring cell carcinoma (SRC). Therefore, a retrospective review was undertaken of 219 patients with SRC who had undergone gastrectomy between January 2009 and December 2012 in our hospital. Patient age, sex, TNM...

journal_title：Technology in cancer research & treatment

authors： Yu JM,Zhan ZW,Zhen JX,Wang XJ,Chen Y,Lin J,Chen L,Chen LZ,Huang YF,Guo ZQ

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Tissue differentiation-inducing non-protein coding RNA (TINCR) has been shown to play a crucial role in pathogenesis of various types of human cancer including breast cancer (BC). The purpose of this study was to determine the potential prognostic value of serum lncRNA TINCR in BC. METHODS:Quantitative reve...

journal_title：Technology in cancer research & treatment

authors： Wang X,Li S,Xiao H,Deng X

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To confirm the feasibility and accuracy of the method for evaluating blood supply and embolization rate of liver cancer based on I-flow software through animal experiments and clinical study. METHODS:Rabbits underwent selective angiography under different perfusion conditions in the same kidney. The blood su...

journal_title：Technology in cancer research & treatment

authors： Li Y,Zhou F,Liu F,Wang M,Xing W

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Gene expression profiles from early-onset breast cancer and normal tissues were analyzed to explore the genes and prognostic factors associated with breast cancer. METHODS:GSE109169 and GSE89116 were obtained from the database of Gene Expression Omnibus. We firstly screened the differentially expressed gene...

journal_title：Technology in cancer research & treatment

authors： Yu Z,He Q,Xu G

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Recent studies have confirmed that immune-associated genes perform a crucial function in recurrence and metastasis of thyroid carcinoma. A reliable immune-related prognostic signature for patients with thyroid cancer is needed. This study constructed a novel immune-related prognostic signature for thyroid ca...

journal_title：Technology in cancer research & treatment

authors： Xue Y,Li J,Lu X

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The biological function of deoxycytidine kinase in tumor is not yet clear, and there are a few studies relating to the correlation of deoxycytidine kinase gene with the occurrence and development of liver cancer. METHODS:The messenger RNA expression of deoxycytidine kinase was analyzed with the use of the U...

journal_title：Technology in cancer research & treatment

authors： Hu SF,Lin X,Xu LP,Chen HG,Guo JF,Jin L

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To investigate the role of intensity-modulated proton therapy (IMPT) for hepatocellular carcinoma (HCC) patients to be treated with stereotactic body radiation therapy (SBRT) in a risk-adapted dose prescription regimen. METHODS:A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escala...

journal_title：Technology in cancer research & treatment

authors： Cozzi L,Comito T,Loi M,Fogliata A,Franzese C,Franceschini D,Clerici E,Reggiori G,Tomatis S,Scorsetti M

更新日期：2020-01-01 00:00:00

abstract：:Our study was designed to investigate the role of B4GalT1 in glioblastoma, in vitro and in vivo, to detect whether B4GalT1 knockdown could regulate the development of glioblastoma, and further observe the relationship between B4GalT1 knockdown and the apoptosis and autophagy of glioblastoma. To begin, we looked at TCG...

journal_title：Technology in cancer research & treatment

authors： Wang P,Li X,Xie Y

更新日期：2020-01-01 00:00:00

abstract：:Breast cancer remains one of the leading causes of cancer-associated death in women. MiR-27a is highly expressed in breast cancer tissue. However, the underlying mechanisms that promote breast cancer progression are unknown. In this study, we investigated the regulatory mechanisms of miR-27a and its target glycogen Sy...

journal_title：Technology in cancer research & treatment

authors： Chen H,Zhang Y,Cao X,Mou P

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Nasopharyngeal carcinoma is highly endemic in Southeast China. Circulating tumor cell is an important biomarker in the prognosis of variety kinds of cancers. Overexpression of fibronectin 1 was observed in variety kinds of malignancies and may contribute to progress and metastasis of the cancers. The current ...

journal_title：Technology in cancer research & treatment

authors： Yu Y,Lin ZX,Li HW,Luo HQ,Yang DH,Zhou HC,Jiang DX,Zhan DC,Yang L,Liang XY,Yu ZH,Chen ZH

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Neoadjuvant chemoradiotherapy (nCRT) followed by operation has become the standard treatment for locally advanced rectal cancer (LARC). However, considering the possible toxicity and complications of radiochemotherapy, nCRT is seldom used for the elderly. The purpose of this study was to assess the safety ...

journal_title：Technology in cancer research & treatment

authors： Liu H,Li C,Zhao Z,Guan X,Yang M,Liu Z,Tang Y,Jiang Z,Wang X

更新日期：2020-01-01 00:00:00

abstract：:Complement 3a (C3a) and complement 5a (C5a), small cleavage fragments generated by complement activation, has been previously shown to be obviously up-regulated in highly metastatic hepatocellular carcinoma (HCC) cells. However, their functional roles in HCC cells remains unclear. Here, we investigated the biological ...

journal_title：Technology in cancer research & treatment

authors： Chen B,Zhou W,Tang C,Wang G,Yuan P,Zhang Y,Bhushan SC,Ma J,Leng J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The incidence of nasopharyngeal carcinoma is increasing gradually, but the pathogenesis is not completely clear. MicroRNA, a highly conserved endogenous noncoding small molecule RNA, plays an essential role in the regulation of gene expression and is a hotspot in cancer research worldwide. OBJECTIVES:Althou...

journal_title：Technology in cancer research & treatment

authors： Xuefang Z,Ruinian Z,Liji J,Chun Z,Qiaolan Z,Jun J,Yuming C,Junrong H

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Acute myeloid leukemia (AML) represents a hematological cancer. The aim of the investigation was to probe the regulatory relevance of long non-coding RNA (lncRNA) aspartyl-tRNA synthetase anti-sense 1 (DARS-AS1)/microRNA-425 (miR-425)/transforming growth factor-beta 1 (TGFB1) to the development of AML. METHO...

journal_title：Technology in cancer research & treatment

authors： Dou B,Jiang Z,Chen X,Wang C,Wu J,An J,Sheng G

更新日期：2020-01-01 00:00:00

abstract：:MicroRNAs are reported as a vital important factor in cancer cell initiation and progression processes. MicroRNA-19-3p has drawn the attention of many researchers in recent years because of its wide expression and its key role in serious kinds of tumor cells. However, the detailed mechanism of microRNA-19a-3p in these...

journal_title：Technology in cancer research & treatment

authors： Su YF,Zang YF,Wang YH,Ding YL

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The incidence of colorectal cancer is increasing every year, and autophagy may be related closely to the pathogenesis of colorectal cancer. Autophagy is a natural catabolic mechanism that allows the degradation of cellular components in eukaryotic cells. However, autophagy plays a dual role in tumorigenesis. ...

journal_title：Technology in cancer research & treatment

authors： Liu TT,Liu SM

更新日期：2020-01-01 00:00:00

abstract：:As one of the common cancers that threaten human life, the recurrence and metastasis of colorectal cancer seriously affect the prognosis of patients. Although new drugs and comprehensive treatments have been adopted, the current treatment effect on this tumor, especially in advanced colorectal cancer, is still not sat...

journal_title：Technology in cancer research & treatment

authors： Ma YS,Li W,Liu Y,Shi Y,Lin QL,Fu D

更新日期：2020-01-01 00:00:00

abstract：:We previously showed that microRNA-182 (miR-182) might promote cell proliferation and migration in triple-negative breast cancer (TNBC). This study aimed to investigate circular RNAs (circRNAs) that interact with miR-182 and play important roles in TNBC. Thirty patients with TNBC were enrolled. One pair of tumor and a...

journal_title：Technology in cancer research & treatment

authors： Yu J,Shen W,Xu J,Gong B,Gao B,Zhu J

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Long noncoding RNAs (lncRNAs) are potential biomarkers for cancers. Nevertheless, the ability of long noncoding RNA lung cancer-associated transcript 1 in patients with multiple myeloma remains unknown. The purpose of this current study was to figure out its function in multiple myeloma. METHODS:Firstly, the...

journal_title：Technology in cancer research & treatment

authors： Liu Z,Gao H,Peng Q,Yang Y

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:We aimed to identify the expression of Sal-like 4 (SALL4) in breast cancer tissues and to explore the role of this gene in the carcinogenesis of breast cancer cells. METHODS:A total of 62 paired breast cancer and noncancerous tissue samples were obtained from patients with breast cancer. SALL4 expression pat...

journal_title：Technology in cancer research & treatment

authors： Liu C,Yao F,Mao X,Li W,Chen H

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:A meta-analysis was conducted to evaluate the diagnostic performance of contrast-enhanced ultrasonography using the contrast agent SonoVue to differentiate benign from malignant breast lesions. METHOD:A comprehensive search of the literature was performed using the Embase, PubMed, and Web of Science databases ...

journal_title：Technology in cancer research & treatment

authors： Lu J,Zhou P,Jin C,Xu L,Zhu X,Lian Q,Gong X

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To develop and evaluate an automatic intensity-modulated radiation therapy (IMRT) program for cervical cancer, including a Convolution Neural Network (CNN)-based prediction model and an automated optimization strategy. METHODS:A CNN deep learning model was trained to predict a patient-specify set of IMRT objec...

journal_title：Technology in cancer research & treatment

authors： Jihong C,Penggang B,Xiuchun Z,Kaiqiang C,Wenjuan C,Yitao D,Jiewei Q,Kerun Q,Jing Z,Tianming W

更新日期：2020-01-01 00:00:00

abstract：:Circular RNAs are a recently discovered subclass of endogenous noncoding RNAs that have been confirmed to play an important role in various pathophysiological processes. However, the underlying function of circular RNAs in osteosarcoma still remains unclear. We aimed to comprehend the function of circ_0032462 in osteo...

journal_title：Technology in cancer research & treatment

authors： Gu R,Li X,Yan X,Feng Z,Hu A

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Osteosarcoma is the most common primary tumor of bone, although some molecular markers have been identified, the detailed molecular mechanisms underlying osteosarcoma are currently not fully understood. In the present study, we attempted to identify the potential key genes and pathways in osteosarcoma usin...

journal_title：Technology in cancer research & treatment

authors： Li Q,Liang J,Chen B

更新日期：2020-01-01 00:00:00

abstract：:Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient studies been performed investigating the part of long noncoding R...

journal_title：Technology in cancer research & treatment

authors： Sun KK,Shen XJ,Yang D,Jiao Y,Wu XY

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Rectal cancer ranks as the eighth in cancer-related morbidity and the tenth in the cancer-related mortality. A few studies have explored several biomarkers for colorectal cancer. However, there is still a great need for us to excavate novel biomarkers with effective and efficient diagnostic and prognostic ...

journal_title：Technology in cancer research & treatment

authors： Xu Z,Li Y,Cui Y,Guo Y

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Disabled homolog 2-interacting protein is a new member of the Ras GTPase superfamily involved in the regulation of cell proliferation, apoptosis, and metastasis. However, the expression of disabled homolog 2-interacting protein in renal cell carcinoma, its correlation with cancer prognosis, and tumor infiltr...

journal_title：Technology in cancer research & treatment

authors： Cao H,Zhang J,Wang W

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To evaluate and quantify the planning performance of automatic planning (AP) with manual planning (MP) for nasopharyngeal carcinoma in the RayStation treatment planning system (TPS). METHODS:A progressive and effective design method for AP of nasopharyngeal carcinoma was realized through automated scripts in...

journal_title：Technology in cancer research & treatment

authors： Yang Y,Shao K,Zhang J,Chen M,Chen Y,Shan G

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The blue laser imaging is a kind of new endoscopic system, sending 2 different wavelengths of laser. RESULT:It can observed that the gastrointestinal mucosa shallow capillaries and mucosal surface microstructure are shown in bright and high resolution images, thus being helpful to the diagnosis of early dig...

journal_title：Technology in cancer research & treatment

authors： Bi Y,Min M,Zhang F,Li X

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate long-term outcomes and prognostic factors of laparoscopic microwave ablation as a first-line treatment for hepatocellular carcinoma located at the liver surface not feasible for percutaneous ablation. METHODS:51 consecutive patients receiving laparoscopic microwave ablation in our cente...

journal_title：Technology in cancer research & treatment

authors： Wang T,Zhang XY,Lu X,Zhai B

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Palliation of advanced disease using radiotherapy can create difficult clinical situations where standard computed tomography simulation and immobilization techniques are not feasible. We developed a linear accelerator-based radiotherapy simulation technique using nonstandard patient positioning for head and...

journal_title：Technology in cancer research & treatment

authors： Dyer BA,Nair CK,Deardorff CE,Wright CL,Perks JR,Rao SS

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To investigate the application value of apparent diffusion coefficient value in the pathological type, histologic grade, and presence of lymph node metastases of esophageal carcinoma. MATERIALS AND METHODS:Eighty-six patients with pathologically confirmed esophageal carcinoma were divided into different grou...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Bai G,Guo L,Chen W

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Osteosarcoma is a common malignant bone tumor that is frequently found in the long bones of children and adolescents. The aim of this study is to examine long noncoding RNA-steroid receptor RNA activator 1 expression in osteosarcoma to explore the biological function of long noncoding RNA steroid receptor RNA...

journal_title：Technology in cancer research & treatment

authors： Guo W,Jiang H,Li H,Li F,Yu Q,Liu Y,Jiang W,Zhang M

更新日期：2019-01-01 00:00:00