Computer assisted analysis of MR-mammography reveals association between contrast enhancement and occurrence of distant metastasis.

abstract：:We previously showed that microRNA-182 (miR-182) might promote cell proliferation and migration in triple-negative breast cancer (TNBC). This study aimed to investigate circular RNAs (circRNAs) that interact with miR-182 and play important roles in TNBC. Thirty patients with TNBC were enrolled. One pair of tumor and a...

journal_title：Technology in cancer research & treatment

authors： Yu J,Shen W,Xu J,Gong B,Gao B,Zhu J

更新日期：2020-01-01 00:00:00

abstract：:The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C(60)(OH)(24) in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Experiment was performed on adult female Spra...

journal_title：Technology in cancer research & treatment

authors： Injac R,Perse M,Boskovic M,Djordjevic-Milic V,Djordjevic A,Hvala A,Cerar A,Strukelj B

更新日期：2008-02-01 00:00:00

abstract：:Intensity-modulated radiation therapy (IMRT) has gained rapid and wide-spread acceptance in the radiation oncology community for its ability to create dose distributions that conform to the convoluted shapes of many tumors. It is a complicated treatment technique, for which quality assurance procedures are correspondi...

journal_title：Technology in cancer research & treatment

authors： Ibbott GS,Molineu A,Followill DS

更新日期：2006-10-01 00:00:00

abstract：:The purpose of the investigation was to assess positron emission tomography (PET), computed tomography (CT) and the image fusion of PET and CT (PET/CT) in the detection of metastases from gastrointestinal neuroendocrine tumors. In a prospective study, thirty-one patients were consecutively examined using a state-of-th...

journal_title：Technology in cancer research & treatment

authors： Seemann MD

更新日期：2007-06-01 00:00:00

abstract：:The present approach at our institution for the treatment of patients with colorectal (CRC) cancer and with liver metastases planned for metastasectomy is the neoadjuvant administration of Bevacizumab with Irinotecan based therapy. Metabolic imaging of tumor viability with 18F-fluorodeoxyglucose (FDG) positron emissio...

journal_title：Technology in cancer research & treatment

authors： Goshen E,Davidson T,Zwas ST,Aderka D

更新日期：2006-02-01 00:00:00

abstract：:Targeted immunotherapy using dendritic cell vaccine has been employed for the treatment of solid tumors. Topical 5-aminolevulinic acid-mediated photodynamic therapy, an established approach for topical cancers, can induce an effective antitumor immune response. We have previously shown that 5-aminolevulinic acid-media...

journal_title：Technology in cancer research & treatment

authors： Zhang H,Wang P,Wang X,Shi L,Fan Z,Zhang G,Yang D,Bahavar CF,Zhou F,Chen WR,Wang X

更新日期：2018-01-01 00:00:00

abstract：:This review addresses the epidemiology, historical reports, current issues, data and controversies involved in the management of brain metastases. The literature regarding surgery, whole brain radiation therapy, stereotactic radiosurgery or some combination of those treatments is discussed as well as issues of cost-ef...

journal_title：Technology in cancer research & treatment

authors： Sperduto PW

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:We recently developed a novel, open-source in vivo dosimetry that uses the electronic portal imaging device to detect dose delivery discrepancies. We applied our method on patients with rectal cancer treated on a belly board device. METHODS:In vivo dosimetry was performed on 10 patients with rectal cancer trea...

journal_title：Technology in cancer research & treatment

authors： Peca S,Sinha RS,Brown DW,Smith WL

更新日期：2017-12-01 00:00:00

abstract：:Tumor-infiltrating immune cells are part of a complex microenvironment and associated with improved clinical outcomes in a broad range of tumor types. However, a detailed map for the prognostic landscape of tumor-infiltrating immune cells and immune checkpoint modulators in glioblastoma is still lacking. Here, with th...

journal_title：Technology in cancer research & treatment

authors： Wu S,Yang W,Zhang H,Ren Y,Fang Z,Yuan C,Yao Z

更新日期：2019-01-01 00:00:00

abstract：:The inhibitor of growth (ING) family proteins have been defined as candidate tumor suppressors. ING4 as a novel member of ING family has potential tumor-suppressive effects via multiple pathways. However, the therapeutic effect of adenovirus-mediated ING4 (Ad-ING4) gene transfer in human osteosarcoma is still unknown....

journal_title：Technology in cancer research & treatment

authors： Xu M,Xie Y,Sheng W,Miao J,Yang J

更新日期：2015-10-01 00:00:00

abstract：:We investigated the technique, early results and toxicity of curative stereotactic radiotherapy with the CyberKnife (Accuray Incorporated, Sunnyvale, California, USA) in 15 extracranial, extrapulmonary, extrahepatic, and extraspinal tumors. Fourteen tumors were located close to the bowel or esophagus. The PTV = GTV + ...

journal_title：Technology in cancer research & treatment

authors： Nuyttens JJ,Prevost JB,Van der Voort van Zijp NC,Hoogeman M,Levendag PC

更新日期：2007-12-01 00:00:00

abstract：:Despite remarkable progress in diagnosis and treatment, malignant glioma, a highly lethal cancer of the central nervous system, remains incurable. Although glioma stem-like cells (GSCs) represent a relatively small fraction of the cells in malignant glioma, they can proliferate and self renew extensively, being crucia...

journal_title：Technology in cancer research & treatment

authors： Xu ZY,Li XQ,Chen S,Cheng Y,Deng JM,Wang ZG

更新日期：2012-12-01 00:00:00

abstract：:The incidence of optic neuropathy after stereotactic radiosurgery (SRS) is related to the total dose, fraction size, and treatment volume. Theoretically, fractionated SRS can decrease this risk. In this paper, we report our technique for fractionated SRS and assess its potential role in the management of tumors locate...

journal_title：Technology in cancer research & treatment

authors： Mehta VK,Lee QT,Chang SD,Cherney S,Adler JR Jr

更新日期：2002-06-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to compare the prognostic value of the percentage of positive biopsy cores (PPBC), the percentage of cancer volume (PCV), and the maximum involvement of biopsy cores (MIBC) as a prognostic factor in low- and intermediate-risk patients with clinically localized prostate cancer wh...

journal_title：Technology in cancer research & treatment

authors： Slater JM,Bush DA,Grove R,Slater JD

更新日期：2014-06-01 00:00:00

abstract：:Lung carcinoma is the most frequently diagnosed malignancy in the world, with the incidence increasing through the 20th century. Presentation may be as a tumor mass primarily obstructing the central bronchial lumen, or a mass infiltrating lung tissue. Cryosurgery can be used as a method of palliative treatment for bot...

journal_title：Technology in cancer research & treatment

authors： Maiwand MO,Asimakopoulos G

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Gene expression profiles from early-onset breast cancer and normal tissues were analyzed to explore the genes and prognostic factors associated with breast cancer. METHODS:GSE109169 and GSE89116 were obtained from the database of Gene Expression Omnibus. We firstly screened the differentially expressed gene...

journal_title：Technology in cancer research & treatment

authors： Yu Z,He Q,Xu G

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:The efficacy of image-guided high-dose rate brachytherapy for cervical cancer is limited by the ineffective rectal sparing devices available commercially and the potential applicator movement. We developed a novel device using a balloon catheter and a belt immobilization system, serving for rectal dose reductio...

journal_title：Technology in cancer research & treatment

authors： Fan Q,Yeung AR,Amdur R,Helmig R,Park J,Li J,Kahler D,Liu C,Lu B

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. MATERIALS AND METHODS:A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identi...

journal_title：Technology in cancer research & treatment

authors： Korpics M,Johnson P,Patel R,Surucu M,Choi M,Emami B,Roeske JC

更新日期：2016-12-01 00:00:00

abstract：:A specific protein profile that accompanies neoplastic transformation in the premalignant airway epithelium could provide an opportunity for early diagnosis of lung cancer. The aim of this study was to screen and identify early candidate biomarkers of non-small cell lung cancer. Thirteen non-small cell lung cancer sam...

journal_title：Technology in cancer research & treatment

authors： Nan Y,Du J,Ma L,Jiang H,Jin F,Yang S

更新日期：2017-02-01 00:00:00

abstract：:Glypican-3 has been reported to be one of the most promising serum markers for hepatocellular carcinoma. This study aimed to assess the clinical utility of serum glypican 3 for the diagnosis of hepatocellular carcinoma. We recruited consecutive patients on a large scale, 283 with hepatocellular carcinoma, 445 with chr...

journal_title：Technology in cancer research & treatment

authors： Jia X,Gao Y,Zhai D,Liu J,Cai J,Wang Y,Jing L,Du Z

更新日期：2016-12-01 00:00:00

abstract：:A 51 year old male with a history of right facial numbness developed progressive upper lip swelling for one year, but an MRI of the head was unremarkable. A wide local excision of the upper lip was performed and pathology revealed a 1.7 cm mass, poorly differentiated squamous cell carcinoma with perineural invasion. S...

journal_title：Technology in cancer research & treatment

authors： Bhatnagar AK,Heron DE,Schaitkin B

更新日期：2005-06-01 00:00:00

abstract：INTRODUCTION:Osteosarcoma is the most common primary tumor of bone, although some molecular markers have been identified, the detailed molecular mechanisms underlying osteosarcoma are currently not fully understood. In the present study, we attempted to identify the potential key genes and pathways in osteosarcoma usin...

journal_title：Technology in cancer research & treatment

authors： Li Q,Liang J,Chen B

更新日期：2020-01-01 00:00:00

abstract：:Circular RNAs are a recently discovered subclass of endogenous noncoding RNAs that have been confirmed to play an important role in various pathophysiological processes. However, the underlying function of circular RNAs in osteosarcoma still remains unclear. We aimed to comprehend the function of circ_0032462 in osteo...

journal_title：Technology in cancer research & treatment

authors： Gu R,Li X,Yan X,Feng Z,Hu A

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the mechanisms involved with miRNA-708 and its targeting of bone morphogenetic protein and activin membrane-bound inhibitor in cell proliferation, migration, and apoptosis in mice with melanoma via the Wnt and transforming growth factor β signaling pathways. METHODS:Sixt...

journal_title：Technology in cancer research & treatment

authors： Lu HJ,Yan J,Jin PY,Zheng GH,Zhang HL,Bai M,Wu DM,Lu J,Zheng YL

更新日期：2018-01-01 00:00:00

abstract：:Many conventional chemotherapeutic drugs, as well as DNA for cancer gene therapy, require efficient access to the cell interior to be effective. The cell membrane is a formidable barrier to many of these drugs, including therapeutic DNA constructs. Electropermeabilization (EP, often used synonymously with "electropora...

journal_title：Technology in cancer research & treatment

authors： Rabussay DP,Nanda GS,Goldfarb PM

更新日期：2002-02-01 00:00:00

abstract：:The response of the tumor microvasculature to ionizing radiation can be modified to improve tumor control in preclinical mouse models of cancer. Recent studies have shown that a variety of cancer drugs can improve the response of cancers to radiotherapy. Protein tyrosine kinase inhibitors (TKIs) have been shown to enh...

journal_title：Technology in cancer research & treatment

authors： Lu B,Shinohara ET,Edwards E,Geng L,Tan J,Hallahan DE

更新日期：2005-12-01 00:00:00

abstract：:Epithelial ovarian cancer has the highest mortality rate among the gynecologic cancers and spreads beyond the ovary in 90% of the women diagnosed with ovarian cancer. Detection before the disease has spread beyond the ovary would significantly improve the survival from ovarian cancer, which is currently only 30% over ...

journal_title：Technology in cancer research & treatment

authors： Brewer MA,Utzinger U,Barton JK,Hoying JB,Kirkpatrick ND,Brands WR,Davis JR,Hunt K,Stevens SJ,Gmitro AF

更新日期：2004-12-01 00:00:00

abstract：:Glucose transporter 1 (GLUT1) facilitates the cellular uptake of glucose and is overexpressed in most cancers. The altered expression of GLUT1 may influence the sensitivity of tumor cells to chemotherapy. This study investigated whether the knockdown of GLUT1 expression to sensitize head and neck cancer cells to the c...

journal_title：Technology in cancer research & treatment

authors： Wang YD,Li SJ,Liao JX

更新日期：2013-12-01 00:00:00

abstract：:We used a shifted-excitation Raman difference spectroscopy method for the ex vivo classification of resected and formalin-fixed breast tissue samples as normal (healthy) tissue, fibroadenoma, or invasive carcinoma. We analyzed 8 tissue samples containing invasive carcinoma that were surrounded by normal tissue and 3 t...

journal_title：Technology in cancer research & treatment

authors： Gebrekidan MT,Erber R,Hartmann A,Fasching PA,Emons J,Beckmann MW,Braeuer A

更新日期：2018-01-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) and Protein kinase B (PKB/Akt) play a crucial role in the formation of many malignant tumors and have been shown to be the important therapeutic targets. In the present study, we examined immunohistochemical expression of phosphorylated Akt (p-Akt) and COX-2 in 45 gastric adenocarcinomas with ...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Zhang QY,Fu YC,Wang T,Zhang J,Xu P,Zhou X,Pu PY,Kang CS

更新日期：2009-12-01 00:00:00