A review of stereotactic radiosurgery in the management of brain metastases.

abstract：:As one of the common cancers that threaten human life, the recurrence and metastasis of colorectal cancer seriously affect the prognosis of patients. Although new drugs and comprehensive treatments have been adopted, the current treatment effect on this tumor, especially in advanced colorectal cancer, is still not sat...

journal_title：Technology in cancer research & treatment

authors： Ma YS,Li W,Liu Y,Shi Y,Lin QL,Fu D

更新日期：2020-01-01 00:00:00

abstract：:A fiber confocal back scattering micro-spectrometer (FCBS) was established, which combined fiber confocal microscopy with light scattering spectroscopy (LSS) for early diagnosis of the cancer cell at cellular level. An adherent monolayer human normal gastric epithelium line GES-1 and a carcinoma cell line NCI-N87 as w...

journal_title：Technology in cancer research & treatment

authors： Wang C,Li Y,Liu G,Ma J,Li Z,Wei X

更新日期：2011-10-01 00:00:00

abstract：:A specific protein profile that accompanies neoplastic transformation in the premalignant airway epithelium could provide an opportunity for early diagnosis of lung cancer. The aim of this study was to screen and identify early candidate biomarkers of non-small cell lung cancer. Thirteen non-small cell lung cancer sam...

journal_title：Technology in cancer research & treatment

authors： Nan Y,Du J,Ma L,Jiang H,Jin F,Yang S

更新日期：2017-02-01 00:00:00

abstract：:Targeted immunotherapy using dendritic cell vaccine has been employed for the treatment of solid tumors. Topical 5-aminolevulinic acid-mediated photodynamic therapy, an established approach for topical cancers, can induce an effective antitumor immune response. We have previously shown that 5-aminolevulinic acid-media...

journal_title：Technology in cancer research & treatment

authors： Zhang H,Wang P,Wang X,Shi L,Fan Z,Zhang G,Yang D,Bahavar CF,Zhou F,Chen WR,Wang X

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To develop and evaluate an automatic intensity-modulated radiation therapy (IMRT) program for cervical cancer, including a Convolution Neural Network (CNN)-based prediction model and an automated optimization strategy. METHODS:A CNN deep learning model was trained to predict a patient-specify set of IMRT objec...

journal_title：Technology in cancer research & treatment

authors： Jihong C,Penggang B,Xiuchun Z,Kaiqiang C,Wenjuan C,Yitao D,Jiewei Q,Kerun Q,Jing Z,Tianming W

更新日期：2020-01-01 00:00:00

abstract：:Signal transduction pathways play a crucial role in breast cancer development, progression, and response to different therapies. A major problem in breast cancer therapy is the heterogeneity among different tumor types and cell lines commonly used in preclinical studies. To characterize the signaling pathways of some ...

journal_title：Technology in cancer research & treatment

authors： Akkiprik M,Nicorici D,Cogdell D,Jia YJ,Hategan A,Tabus I,Yli-Harja O,Y D,Sahin A,Zhang W

更新日期：2006-12-01 00:00:00

abstract：:Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...

journal_title：Technology in cancer research & treatment

authors： ten Hagen TL,Eggermont AM

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:To investigate the role of intensity-modulated proton therapy (IMPT) for hepatocellular carcinoma (HCC) patients to be treated with stereotactic body radiation therapy (SBRT) in a risk-adapted dose prescription regimen. METHODS:A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escala...

journal_title：Technology in cancer research & treatment

authors： Cozzi L,Comito T,Loi M,Fogliata A,Franzese C,Franceschini D,Clerici E,Reggiori G,Tomatis S,Scorsetti M

更新日期：2020-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most aggressive type of gastrointestinal tumor, with a high rate of mortality. However, identifying biomarkers for the treatment of HCC remains to be developed. We aimed to determine whether cell division cycle 25C (CDC25C) could be used as a novel diagnostic and therapeutic bioma...

journal_title：Technology in cancer research & treatment

authors： Xun R,Lu H,Wang X

更新日期：2020-01-01 00:00:00

abstract：:In recent years, the imaging of drug-induced apoptosis has become one of the centers of interest in experimental and clinical research. In particular, the accurate monitoring of chemosensitivity as well as the early prediction of chemoresistance in response to various pro-apoptotic interventions are critical requireme...

journal_title：Technology in cancer research & treatment

authors： Belhocine T,Steinmetz N,Li C,Green A,Blankenberg FG

更新日期：2004-02-01 00:00:00

abstract：:The purpose of this research is to establish a process of irradiating mice using the Gamma Knife as a versatile system for small animal irradiation and to validate accurate intracranial and extracranial dose delivery using this system. A stereotactic immobilization device was developed for small animals for the Gamma ...

journal_title：Technology in cancer research & treatment

authors： Awan MJ,Dorth J,Mani A,Kim H,Zheng Y,Mislmani M,Welford S,Yuan J,Wessels BW,Lo SS,Letterio J,Machtay M,Sloan A,Sohn JW

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Palliation of advanced disease using radiotherapy can create difficult clinical situations where standard computed tomography simulation and immobilization techniques are not feasible. We developed a linear accelerator-based radiotherapy simulation technique using nonstandard patient positioning for head and...

journal_title：Technology in cancer research & treatment

authors： Dyer BA,Nair CK,Deardorff CE,Wright CL,Perks JR,Rao SS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Tissue differentiation-inducing non-protein coding RNA (TINCR) has been shown to play a crucial role in pathogenesis of various types of human cancer including breast cancer (BC). The purpose of this study was to determine the potential prognostic value of serum lncRNA TINCR in BC. METHODS:Quantitative reve...

journal_title：Technology in cancer research & treatment

authors： Wang X,Li S,Xiao H,Deng X

更新日期：2020-01-01 00:00:00

abstract：:At external beam radiotherapy, stereoscopic X-ray imaging system is responsible as tumor motion information provider. This system takes X-ray images intermittently from tumor position (1) at pretreatment step to provide training data set for model construction and (2) during treatment to control the accuracy of correl...

journal_title：Technology in cancer research & treatment

authors： Esmaili Torshabi A,Ghorbanzadeh L

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:To confirm the feasibility and accuracy of the method for evaluating blood supply and embolization rate of liver cancer based on I-flow software through animal experiments and clinical study. METHODS:Rabbits underwent selective angiography under different perfusion conditions in the same kidney. The blood su...

journal_title：Technology in cancer research & treatment

authors： Li Y,Zhou F,Liu F,Wang M,Xing W

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To evaluate 2 simultaneous integrated boost treatment planning techniques using helical tomotherapy for breast conserving therapy with regard to acute skin toxicity and dosimetry. METHODS:Thirty-two patients were studied. The original approach was for 16 patients and incorporated a directional block of the ips...

journal_title：Technology in cancer research & treatment

authors： Wojcieszynski AP,Olson AK,Rong Y,Kimple RJ,Yadav P

更新日期：2016-04-01 00:00:00

abstract：AIM:To explore the relationship of clinicopathological features and the proteins of C-met expression in the prognosis of cholangiocarcinoma. METHODS:Clinical data and the completed follow-up information of patients with cholangiocarcinoma who underwent cholangiocarcinoma operation from January 2004 to December 2010 we...

journal_title：Technology in cancer research & treatment

authors： Mao ZY,Zhu GQ,Ren L,Guo XC,Su D,Bai L

更新日期：2016-04-01 00:00:00

abstract：:The aim of this study was to evaluate the relationship of prognosis of patients with multiple myeloma having extramedullary involvement (EMM) with the 18F- fluorodeoxyglucose(18F-FDG) maximum standardized uptake value and the expression of Ki-67 in biopsy samples. Sixty-five patients were newly diagnosed with multiple...

journal_title：Technology in cancer research & treatment

authors： Li Q,Ma J,Li H,Xu W,Cao Z,Liu S,Chen L,Gao S,Yan T,Li D,Wang X,Yue Y,Zhao Z,Wang X,Yang H,Zhao H,Yu Y,Zhang Y,Fan F,Wang Y

更新日期：2019-01-01 00:00:00

abstract：:Electrochemotherapy is an effective antitumor treatment employing locally applied high voltage electric pulses delivered through conductive electrodes to the tumor in combination with chemotherapeutic drugs. The efficiency of electrochemotherapy strongly depends on the local electric field distribution inside the targ...

journal_title：Technology in cancer research & treatment

authors： Corovic S,Al Sakere B,Haddad V,Miklavcic D,Mir LM

更新日期：2008-10-01 00:00:00

abstract：:There are many motivations for adding simultaneously acquired MR images to PET scanning. The most straight forward are, superior registration of MR and PET images, the addition of morphological detail when there is non-rigid motion and for pre-clinical studies simultaneous imaging could lead to a significant reduction...

journal_title：Technology in cancer research & treatment

authors： Hawkes RC,Fryer TD,Siegel S,Ansorge RE,Carpenter TA

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the efficacy and toxicity of robotic CyberKnife (Accuray Incorporated, Sunnyvale, California)-based stereotactic body radiation therapy (SBRT) in patients with recurrent or metastatic abdominopelvic tumors. METHODS AND MATERIALS:A total of 69 patients treated between Ma...

journal_title：Technology in cancer research & treatment

authors： Sezen D,Gurkaynak M,Gultekin M,Cengiz M,Yildiz F,Zorlu F,Akyol F,Yazici G,Hurmuz P,Ozyigit G

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the mechanisms involved with miRNA-708 and its targeting of bone morphogenetic protein and activin membrane-bound inhibitor in cell proliferation, migration, and apoptosis in mice with melanoma via the Wnt and transforming growth factor β signaling pathways. METHODS:Sixt...

journal_title：Technology in cancer research & treatment

authors： Lu HJ,Yan J,Jin PY,Zheng GH,Zhang HL,Bai M,Wu DM,Lu J,Zheng YL

更新日期：2018-01-01 00:00:00

abstract：:This study was performed to observe the effect of the combination of nimotuzumab with radiation or gemcitabine-based chemoradiation on antipancreatic cancer cell therapy. Pancreatic cancer cells (PANC-1) were treated with nimotuzumab alone or combined with radiation (2, 4, or 8 Gy), which was either with or without ge...

journal_title：Technology in cancer research & treatment

authors： Gao C,Wu X,Yan Y,Meng L,Shan D,Li Y,Han B

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To investigate the application value of apparent diffusion coefficient value in the pathological type, histologic grade, and presence of lymph node metastases of esophageal carcinoma. MATERIALS AND METHODS:Eighty-six patients with pathologically confirmed esophageal carcinoma were divided into different grou...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Bai G,Guo L,Chen W

更新日期：2019-01-01 00:00:00

abstract：:Stereotactic radiosurgery (SRS) refers to a single radiation treatment delivering a high dose to an intra-cranial target localized in three-dimensions by CT and/or MRI imaging. Traditionally, immobilization of the patient's head has been achieved using a rigid stereotactic head frame as the key step in allowing for ac...

journal_title：Technology in cancer research & treatment

authors： Sahgal A,Ma L,Chang E,Shiu A,Larson DA,Laperriere N,Yin FF,Tsao M,Menard C,Basran P,Létourneau D,Heydarian M,Beachey D,Shukla V,Cusimano M,Hodaie M,Zadeh G,Bernstein M,Schwartz M

更新日期：2009-08-01 00:00:00

abstract：:One of the most lethal carcinomas is pancreatic cancer. As standard treatment using chemotherapy and radiation has shown limited success, thermal regimens (cryotherapy or heat ablation) are emerging as viable alternatives. Although promising, our understanding of pancreatic cancer response to thermal ablation remains ...

journal_title：Technology in cancer research & treatment

authors： Baumann KW,Baust JM,Snyder KK,Baust JG,Van Buskirk RG

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Testicular cancer represents the most common malignancy in young adult men. In the current study, we sought to analyze and compare the prognostic value of lymph node ratio (LNR) as well as positive lymph node counts (LNC) to understand its clinical significance in testicular germ cell tumors. METHODS:We emp...

journal_title：Technology in cancer research & treatment

authors： Huang C,Long Q,Pan Y,Wu L,Wang X,Xu H,Zheng F

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Nasopharyngeal carcinoma is highly endemic in Southeast China. Circulating tumor cell is an important biomarker in the prognosis of variety kinds of cancers. Overexpression of fibronectin 1 was observed in variety kinds of malignancies and may contribute to progress and metastasis of the cancers. The current ...

journal_title：Technology in cancer research & treatment

authors： Yu Y,Lin ZX,Li HW,Luo HQ,Yang DH,Zhou HC,Jiang DX,Zhan DC,Yang L,Liang XY,Yu ZH,Chen ZH

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To evaluate and quantify the planning performance of automatic planning (AP) with manual planning (MP) for nasopharyngeal carcinoma in the RayStation treatment planning system (TPS). METHODS:A progressive and effective design method for AP of nasopharyngeal carcinoma was realized through automated scripts in...

journal_title：Technology in cancer research & treatment

authors： Yang Y,Shao K,Zhang J,Chen M,Chen Y,Shan G

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:We investigated the dosimetric effect of intrafraction tumor motion in lung stereotactic body radiotherapy using the CyberKnife static tracking system. METHODS:Four-dimensional computed tomography scans of a dynamic thorax phantom were acquired. Two motion ranges, 3 collimator sizes, and 4 treatment starting p...

journal_title：Technology in cancer research & treatment

authors： Chang Y,Liu HY,Liang ZW,Nie X,Yang J,Liu G,Li Q,Yang ZY

更新日期：2019-01-01 00:00:00