Advances in technology for intracranial stereotactic radiosurgery.

abstract：:Three Asian patients with plasma cell myeloma stage IIIa with IgG predominant were selected for autologous hematopoietic cell transplantation (HSCT). Total marrow irradiation (TMI) tomotherapy planned with melphalan 140 mg/m2 as a preconditioning regimen of HSCT. Two image sets of computed tomography (CT) were scanned...

journal_title：Technology in cancer research & treatment

authors： Shueng PW,Lin SC,Chong NS,Lee HY,Tien HJ,Wu LJ,Chen CA,Lee JJ,Hsieh CH

更新日期：2009-02-01 00:00:00

abstract：:Optical methods such as reflectance and fluorescence spectroscopy are being investigated for their potential to aid cancer detection in a quantitative, minimally invasive manner. Mathematical models of reflectance and fluorescence provide an important link between measured optical data and biomedically-relevant tissue...

journal_title：Technology in cancer research & treatment

authors： Wilson RH,Mycek MA

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:We recently developed a novel, open-source in vivo dosimetry that uses the electronic portal imaging device to detect dose delivery discrepancies. We applied our method on patients with rectal cancer treated on a belly board device. METHODS:In vivo dosimetry was performed on 10 patients with rectal cancer trea...

journal_title：Technology in cancer research & treatment

authors： Peca S,Sinha RS,Brown DW,Smith WL

更新日期：2017-12-01 00:00:00

abstract：:Intensity-modulated radiation therapy (IMRT) has gained rapid and wide-spread acceptance in the radiation oncology community for its ability to create dose distributions that conform to the convoluted shapes of many tumors. It is a complicated treatment technique, for which quality assurance procedures are correspondi...

journal_title：Technology in cancer research & treatment

authors： Ibbott GS,Molineu A,Followill DS

更新日期：2006-10-01 00:00:00

abstract：:The accurate characterization and description of the vascular network of a cancer lesion is of paramount importance in clinical practice and cancer research in order to improve diagnostic accuracy or to assess the effectiveness of a treatment. The aim of this study was to show the effectiveness of liposomes as an ultr...

journal_title：Technology in cancer research & treatment

authors： Molinari F,Meiburger KM,Giustetto P,Rizzitelli S,Boffa C,Castano M,Terreno E

更新日期：2014-12-01 00:00:00

abstract：:Since "Warburg effect" has been firstly uncovered in cancer cells in 1956, mounting evidence has supported the molecular mechanism underlying the energy metabolism in induced chemoresistance in cancers. MicroRNAs can mediate fine-tuning of genes in physiological process. MicroRNAs' energy metabolic role in chemoresist...

journal_title：Technology in cancer research & treatment

authors： Ye J,Zou M,Li P,Liu H

更新日期：2018-01-01 00:00:00

abstract：:Glucose transporter 1 (GLUT1) facilitates the cellular uptake of glucose and is overexpressed in most cancers. The altered expression of GLUT1 may influence the sensitivity of tumor cells to chemotherapy. This study investigated whether the knockdown of GLUT1 expression to sensitize head and neck cancer cells to the c...

journal_title：Technology in cancer research & treatment

authors： Wang YD,Li SJ,Liao JX

更新日期：2013-12-01 00:00:00

abstract：:Targeted immunotherapy using dendritic cell vaccine has been employed for the treatment of solid tumors. Topical 5-aminolevulinic acid-mediated photodynamic therapy, an established approach for topical cancers, can induce an effective antitumor immune response. We have previously shown that 5-aminolevulinic acid-media...

journal_title：Technology in cancer research & treatment

authors： Zhang H,Wang P,Wang X,Shi L,Fan Z,Zhang G,Yang D,Bahavar CF,Zhou F,Chen WR,Wang X

更新日期：2018-01-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) and Protein kinase B (PKB/Akt) play a crucial role in the formation of many malignant tumors and have been shown to be the important therapeutic targets. In the present study, we examined immunohistochemical expression of phosphorylated Akt (p-Akt) and COX-2 in 45 gastric adenocarcinomas with ...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Zhang QY,Fu YC,Wang T,Zhang J,Xu P,Zhou X,Pu PY,Kang CS

更新日期：2009-12-01 00:00:00

abstract：:Recombinant Newcastle Disease Virus (rNDV) has shown oncolytic therapeutic effect in preclinical studies. Previous data indicate that rNDV carrying IL2 has shown promise in cancer therapy. Due to the significant side effects of IL2, IL15 has been introduced into cancer therapy. A number of studies have suggested that ...

journal_title：Technology in cancer research & treatment

authors： Niu Z,Bai F,Sun T,Tian H,Yu D,Yin J,Li S,Li T,Cao H,Yu Q,Wu Y,Ren G,Li D

更新日期：2015-10-01 00:00:00

abstract：:Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...

journal_title：Technology in cancer research & treatment

authors： ten Hagen TL,Eggermont AM

更新日期：2003-06-01 00:00:00

abstract：:Hepatocellular carcinoma is the fourth leading cause of cancer-related death worldwide. Depending on the extent of disease and competing comorbidities for mortality, multiple liver-directed therapy options exist for the treatment of hepatocellular carcinoma. Advancements in radiation oncology have led to the emergence...

journal_title：Technology in cancer research & treatment

authors： Schaub SK,Hartvigson PE,Lock MI,Høyer M,Brunner TB,Cardenes HR,Dawson LA,Kim EY,Mayr NA,Lo SS,Apisarnthanarax S

更新日期：2018-01-01 00:00:00

abstract：:Endoscopic endonasal surgery (EES) has been shown to be a feasible approach to cranial base tumors while reducing post-operative morbidity. Using the endoscopic endonasal approach alone or in combination with open approaches may provide advantages over conventional approaches. However, the balance between maximal rese...

journal_title：Technology in cancer research & treatment

authors： Paravati AJ,Heron DE,Gardner PA,Snyderman C,Ozhasoglu C,Quinn A,Burton SA,Seelman K,Mintz AH

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To confirm the feasibility and accuracy of the method for evaluating blood supply and embolization rate of liver cancer based on I-flow software through animal experiments and clinical study. METHODS:Rabbits underwent selective angiography under different perfusion conditions in the same kidney. The blood su...

journal_title：Technology in cancer research & treatment

authors： Li Y,Zhou F,Liu F,Wang M,Xing W

更新日期：2020-01-01 00:00:00

abstract：:Blood flow is a key parameter in studying cancer angiogenesis and hypermetabolism. Current photoacoustic blood flow estimation methods focus on either the axial or transverse component of the flow vector. However, the Doppler angle (beam-to-flow angle) is needed to calculate the total flow speed, and it cannot always ...

journal_title：Technology in cancer research & treatment

authors： Yao J,Maslov KI,Wang LV

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Antibody resistance, both de novo and acquired, is usually related to high risk of recurrence and lower survival rate in gynecologic cancers. Prevention or reversal of the resistance often yields beneficial clinical results. It was reported that anti-human epidermal growth factor receptor 3 monoclonal antibo...

journal_title：Technology in cancer research & treatment

authors： Li X,Duan Y,Qiao C,Zhou T,Yu M,Geng J,Feng J,Shen B,Lv M,Li Y

更新日期：2016-08-01 00:00:00

abstract：:Endometrial carcinoma is one of the most common cancers in women. A limited number of endometrial carcinoma cell lines are available for studies of signal transduction pathways and experimental therapeutics in vitro. However, these cell lines have not been comprehensively characterized. In this study, we used genome-w...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Yang D,Cogdell D,Hu L,Xue F,Broaddus R,Zhang W

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:The study was aimed to compare online 6 degree-of-freedom image registrations of TrueBeam cone-beam computed tomography and BrainLab ExacTrac X-ray imaging systems for intracranial radiosurgery. METHODS:Phantom and patient studies were performed on a Varian TrueBeam STx linear accelerator (version 2.5), which ...

journal_title：Technology in cancer research & treatment

authors： Li J,Shi W,Andrews D,Werner-Wasik M,Lu B,Yu Y,Dicker A,Liu H

更新日期：2017-06-01 00:00:00

abstract：:Breast cancer remains one of the leading causes of cancer-associated death in women. MiR-27a is highly expressed in breast cancer tissue. However, the underlying mechanisms that promote breast cancer progression are unknown. In this study, we investigated the regulatory mechanisms of miR-27a and its target glycogen Sy...

journal_title：Technology in cancer research & treatment

authors： Chen H,Zhang Y,Cao X,Mou P

更新日期：2020-01-01 00:00:00

abstract：:Our study was designed to investigate the role of B4GalT1 in glioblastoma, in vitro and in vivo, to detect whether B4GalT1 knockdown could regulate the development of glioblastoma, and further observe the relationship between B4GalT1 knockdown and the apoptosis and autophagy of glioblastoma. To begin, we looked at TCG...

journal_title：Technology in cancer research & treatment

authors： Wang P,Li X,Xie Y

更新日期：2020-01-01 00:00:00

abstract：:Irreversible electroporation (IRE) has been shown to be an effective method of killing cells locally. In contrast to radiofrequency ablation, the mechanism by which cells are thought to die via IRE is the creation of pores in cell membranes, without substantial increase in tissue temperature. To determine the degree t...

journal_title：Technology in cancer research & treatment

authors： Long G,Bakos G,Shires PK,Gritter L,Crissman JW,Harris JL,Clymer JW

更新日期：2014-12-01 00:00:00

abstract：:Although an MRI scanner is a single stand-alone modality, different acquisition techniques may be applied to collect structural and functional information, including vascular or angiogenic properties measured by dynamic contrast enhanced MRI (DCE-MRI) and Choline (Cho) metabolism measured by proton MR spectroscopy ima...

journal_title：Technology in cancer research & treatment

authors： Su MY,Baik HM,Yu HJ,Chen JH,Mehta RS,Nalcioglu O

更新日期：2006-08-01 00:00:00

abstract：:At external beam radiotherapy, stereoscopic X-ray imaging system is responsible as tumor motion information provider. This system takes X-ray images intermittently from tumor position (1) at pretreatment step to provide training data set for model construction and (2) during treatment to control the accuracy of correl...

journal_title：Technology in cancer research & treatment

authors： Esmaili Torshabi A,Ghorbanzadeh L

更新日期：2017-04-01 00:00:00

abstract：:This study aimed to analysis outcome and prognosis of interstitial 125I seed implantation in patients with cervical lymph node recurrence after multimodal treatment of thoracic esophageal squamous cell carcinoma (ESCC). We conducted a retrospective review of 19 patients with 32 cervical lymph nodes recurrences after m...

journal_title：Technology in cancer research & treatment

authors： Lin L,Wang J,Jiang Y,Meng N,Tian S,Yang R,Ran W,Liu C

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:The main objective in studying large-scale cancer omics is to identify molecular mechanisms of cancer and discover novel biomedical targets. This work not only discovers the cancer subtypes in genome scale data by using clustering and classification but also measures their accuracy. METHODS:Initially, candid...

journal_title：Technology in cancer research & treatment

authors： Vasudevan P,Murugesan T

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:We aimed to identify the expression of Sal-like 4 (SALL4) in breast cancer tissues and to explore the role of this gene in the carcinogenesis of breast cancer cells. METHODS:A total of 62 paired breast cancer and noncancerous tissue samples were obtained from patients with breast cancer. SALL4 expression pat...

journal_title：Technology in cancer research & treatment

authors： Liu C,Yao F,Mao X,Li W,Chen H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Palliation of advanced disease using radiotherapy can create difficult clinical situations where standard computed tomography simulation and immobilization techniques are not feasible. We developed a linear accelerator-based radiotherapy simulation technique using nonstandard patient positioning for head and...

journal_title：Technology in cancer research & treatment

authors： Dyer BA,Nair CK,Deardorff CE,Wright CL,Perks JR,Rao SS

更新日期：2019-01-01 00:00:00

abstract：:This study quantifies the setup uncertainties to optimize the planning target volume (PTV) margin based on daily image guidance, its dosimetric impact, and radiobiological implication for intensity-modulated radiation therapy (IMRT) in head and neck cancer. Ten patients were retrospectively chosen who had been treated...

journal_title：Technology in cancer research & treatment

authors： Srivastava SP,Cheng CW,Das IJ

更新日期：2016-02-01 00:00:00

abstract：:The ultrasound-guided diffuse optical tomography is a noninvasive imaging technique for breast cancer diagnosis and treatment monitoring. The technique uses a handheld probe capable of providing measurements of multiple wavelengths in a few seconds. These measurements are used to estimate optical absorptions of lesion...

journal_title：Technology in cancer research & treatment

authors： Althobaiti M,Vavadi H,Zhu Q

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate long-term outcomes and prognostic factors of laparoscopic microwave ablation as a first-line treatment for hepatocellular carcinoma located at the liver surface not feasible for percutaneous ablation. METHODS:51 consecutive patients receiving laparoscopic microwave ablation in our cente...

journal_title：Technology in cancer research & treatment

authors： Wang T,Zhang XY,Lu X,Zhai B

更新日期：2019-01-01 00:00:00