Radiosurgery for glomus jugulare tumors.

abstract：:Complement 3a (C3a) and complement 5a (C5a), small cleavage fragments generated by complement activation, has been previously shown to be obviously up-regulated in highly metastatic hepatocellular carcinoma (HCC) cells. However, their functional roles in HCC cells remains unclear. Here, we investigated the biological ...

journal_title：Technology in cancer research & treatment

authors： Chen B,Zhou W,Tang C,Wang G,Yuan P,Zhang Y,Bhushan SC,Ma J,Leng J

更新日期：2020-01-01 00:00:00

abstract：:As one of the common cancers that threaten human life, the recurrence and metastasis of colorectal cancer seriously affect the prognosis of patients. Although new drugs and comprehensive treatments have been adopted, the current treatment effect on this tumor, especially in advanced colorectal cancer, is still not sat...

journal_title：Technology in cancer research & treatment

authors： Ma YS,Li W,Liu Y,Shi Y,Lin QL,Fu D

更新日期：2020-01-01 00:00:00

abstract：:The integrated use of optical technologies for patient monitoring is addressed in the framework of time-resolved treatment delivery for scanned ion beam therapy. A software application has been designed to provide the therapy control system (TCS) with a continuous geometrical feedback by processing the external surrog...

journal_title：Technology in cancer research & treatment

authors： Fattori G,Saito N,Seregni M,Kaderka R,Pella A,Constantinescu A,Riboldi M,Steidl P,Cerveri P,Bert C,Durante M,Baroni G

更新日期：2014-12-01 00:00:00

abstract：:Irreversible electroporation (IRE) has been shown to be an effective method of killing cells locally. In contrast to radiofrequency ablation, the mechanism by which cells are thought to die via IRE is the creation of pores in cell membranes, without substantial increase in tissue temperature. To determine the degree t...

journal_title：Technology in cancer research & treatment

authors： Long G,Bakos G,Shires PK,Gritter L,Crissman JW,Harris JL,Clymer JW

更新日期：2014-12-01 00:00:00

abstract：:The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C(60)(OH)(24) in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Experiment was performed on adult female Spra...

journal_title：Technology in cancer research & treatment

authors： Injac R,Perse M,Boskovic M,Djordjevic-Milic V,Djordjevic A,Hvala A,Cerar A,Strukelj B

更新日期：2008-02-01 00:00:00

abstract：:Since "Warburg effect" has been firstly uncovered in cancer cells in 1956, mounting evidence has supported the molecular mechanism underlying the energy metabolism in induced chemoresistance in cancers. MicroRNAs can mediate fine-tuning of genes in physiological process. MicroRNAs' energy metabolic role in chemoresist...

journal_title：Technology in cancer research & treatment

authors： Ye J,Zou M,Li P,Liu H

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to evaluate the relationship of prognosis of patients with multiple myeloma having extramedullary involvement (EMM) with the 18F- fluorodeoxyglucose(18F-FDG) maximum standardized uptake value and the expression of Ki-67 in biopsy samples. Sixty-five patients were newly diagnosed with multiple...

journal_title：Technology in cancer research & treatment

authors： Li Q,Ma J,Li H,Xu W,Cao Z,Liu S,Chen L,Gao S,Yan T,Li D,Wang X,Yue Y,Zhao Z,Wang X,Yang H,Zhao H,Yu Y,Zhang Y,Fan F,Wang Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The biological function of deoxycytidine kinase in tumor is not yet clear, and there are a few studies relating to the correlation of deoxycytidine kinase gene with the occurrence and development of liver cancer. METHODS:The messenger RNA expression of deoxycytidine kinase was analyzed with the use of the U...

journal_title：Technology in cancer research & treatment

authors： Hu SF,Lin X,Xu LP,Chen HG,Guo JF,Jin L

更新日期：2020-01-01 00:00:00

abstract：:Proteomics is a rapidly expanding discipline that aims to gain a comprehensive understanding of the expressions, modification, interactions, and regulation of proteins in cells. New high-throughput technologies, such as protein chips and isotope-coded affinity tag peptide labeling, coupled with classic technologies su...

journal_title：Technology in cancer research & treatment

authors： Choi W,Song SW,Zhang W

更新日期：2002-08-01 00:00:00

abstract：:Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...

journal_title：Technology in cancer research & treatment

authors： ten Hagen TL,Eggermont AM

更新日期：2003-06-01 00:00:00

abstract：:The microRNA-200 (miR-200) family has been reported to be vital for the inhibition of epithelial-to-mesenchymal transition (EMT) in tumor cells. The miR-200 family represents a complex multi-factorial regulatory network which has not been well described in breast cancer. This study aimed to clarify the underlying regu...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Shao N,Yang X,Xie C,Shi Y,Lin Y

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Osteosarcoma is a common malignant bone tumor that is frequently found in the long bones of children and adolescents. The aim of this study is to examine long noncoding RNA-steroid receptor RNA activator 1 expression in osteosarcoma to explore the biological function of long noncoding RNA steroid receptor RNA...

journal_title：Technology in cancer research & treatment

authors： Guo W,Jiang H,Li H,Li F,Yu Q,Liu Y,Jiang W,Zhang M

更新日期：2019-01-01 00:00:00

abstract：:Tumor-infiltrating immune cells are part of a complex microenvironment and associated with improved clinical outcomes in a broad range of tumor types. However, a detailed map for the prognostic landscape of tumor-infiltrating immune cells and immune checkpoint modulators in glioblastoma is still lacking. Here, with th...

journal_title：Technology in cancer research & treatment

authors： Wu S,Yang W,Zhang H,Ren Y,Fang Z,Yuan C,Yao Z

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:The efficacy of image-guided high-dose rate brachytherapy for cervical cancer is limited by the ineffective rectal sparing devices available commercially and the potential applicator movement. We developed a novel device using a balloon catheter and a belt immobilization system, serving for rectal dose reductio...

journal_title：Technology in cancer research & treatment

authors： Fan Q,Yeung AR,Amdur R,Helmig R,Park J,Li J,Kahler D,Liu C,Lu B

更新日期：2017-06-01 00:00:00

abstract：:The therapy of brain tumors has been limited by a lack of effective methods of drug delivery to the brain. Systemic administration is often associated with toxic side effects and ultimately fails to achieve therapeutic concentrations within a tumor. An attractive strategy that has gained importance in brain tumor ther...

journal_title：Technology in cancer research & treatment

authors： Lesniak MS

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:We aimed to identify the expression of Sal-like 4 (SALL4) in breast cancer tissues and to explore the role of this gene in the carcinogenesis of breast cancer cells. METHODS:A total of 62 paired breast cancer and noncancerous tissue samples were obtained from patients with breast cancer. SALL4 expression pat...

journal_title：Technology in cancer research & treatment

authors： Liu C,Yao F,Mao X,Li W,Chen H

更新日期：2020-01-01 00:00:00

abstract：:Numerous beam directions using 3-D conformal techniques can be employed in treating tumors in the posterior fossa, each with characteristic normal tissue exposure along the entrance and exit trajectory. A representative variety of beam configurations were modeled in a modern computer planning system initially with the...

journal_title：Technology in cancer research & treatment

authors： Timmerman RD,Ewing M,Donges M,Wilson J,Jakacki R,Randall ME

更新日期：2003-12-01 00:00:00

abstract：:Breast cancer remains one of the leading causes of cancer-associated death in women. MiR-27a is highly expressed in breast cancer tissue. However, the underlying mechanisms that promote breast cancer progression are unknown. In this study, we investigated the regulatory mechanisms of miR-27a and its target glycogen Sy...

journal_title：Technology in cancer research & treatment

authors： Chen H,Zhang Y,Cao X,Mou P

更新日期：2020-01-01 00:00:00

abstract：:In cryosurgery it is crucial that the performance of cryoprobes is predictable and constant. In this study we tested the intra- and interneedle variation between 17-gauge cryoprobes in two homogeneous mediums. Also, a multiprobe setup was tested. Cryoprobe performance was defined as the time it takes one cryoprobe to ...

journal_title：Technology in cancer research & treatment

authors： Beemster PW,Lagerveld BW,Witte LP,de la Rosette JJ,Pes MP,Wijkstra H

更新日期：2008-08-01 00:00:00

abstract：:Our results indicate that the surface chemistry, composition, and 3-D structure of nanoparticles are critical in determining their in vivo biodistribution, and therefore the efficacy of nanodevice imaging and therapies. We demonstrate that gold/dendrimer nanocomposites in vivo, present biodistribution characteristics ...

journal_title：Technology in cancer research & treatment

authors： Khan MK,Nigavekar SS,Minc LD,Kariapper MS,Nair BM,Lesniak WG,Balogh LP

更新日期：2005-12-01 00:00:00

abstract：:Stereotactic radiosurgery (SRS) refers to a single radiation treatment delivering a high dose to an intra-cranial target localized in three-dimensions by CT and/or MRI imaging. Traditionally, immobilization of the patient's head has been achieved using a rigid stereotactic head frame as the key step in allowing for ac...

journal_title：Technology in cancer research & treatment

authors： Sahgal A,Ma L,Chang E,Shiu A,Larson DA,Laperriere N,Yin FF,Tsao M,Menard C,Basran P,Létourneau D,Heydarian M,Beachey D,Shukla V,Cusimano M,Hodaie M,Zadeh G,Bernstein M,Schwartz M

更新日期：2009-08-01 00:00:00

abstract：:We have developed a small animal conformal radiation therapy device that provides a degree of geometrical/anatomical targeting comparable to what is achievable in a commercial animal irradiator. small animal conformal radiation therapy device is capable of producing precise and accurate conformal delivery of radiation...

journal_title：Technology in cancer research & treatment

authors： Sharma S,Narayanasamy G,Przybyla B,Webber J,Boerma M,Clarkson R,Moros EG,Corry PM,Griffin RJ

更新日期：2017-02-01 00:00:00

abstract：:MicroRNAs are reported as a vital important factor in cancer cell initiation and progression processes. MicroRNA-19-3p has drawn the attention of many researchers in recent years because of its wide expression and its key role in serious kinds of tumor cells. However, the detailed mechanism of microRNA-19a-3p in these...

journal_title：Technology in cancer research & treatment

authors： Su YF,Zang YF,Wang YH,Ding YL

更新日期：2020-01-01 00:00:00

abstract：:Chemo-radiotherapy is standard treatment of stage IIIA-N2 bulky or IIIB non-small cell lung cancer (NSCLC). Surgical resection of residual disease in downstaged patients may improve overall survival. In this setting, restaging disease is still a challenge. 18F-FDG PET/CT represents the gold standard although accuracy ...

journal_title：Technology in cancer research & treatment

authors： Genestreti G,Burgio MA,Matteucci F,Piciucchi S,Scarpi E,Monti M,Bucchi L,Parisi E,Crociani L,Gurioli C,Poletti V,Gavelli G

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Nasopharyngeal carcinoma is highly endemic in Southeast China. Circulating tumor cell is an important biomarker in the prognosis of variety kinds of cancers. Overexpression of fibronectin 1 was observed in variety kinds of malignancies and may contribute to progress and metastasis of the cancers. The current ...

journal_title：Technology in cancer research & treatment

authors： Yu Y,Lin ZX,Li HW,Luo HQ,Yang DH,Zhou HC,Jiang DX,Zhan DC,Yang L,Liang XY,Yu ZH,Chen ZH

更新日期：2020-01-01 00:00:00

abstract：:Lung carcinoma is the most frequently diagnosed malignancy in the world, with the incidence increasing through the 20th century. Presentation may be as a tumor mass primarily obstructing the central bronchial lumen, or a mass infiltrating lung tissue. Cryosurgery can be used as a method of palliative treatment for bot...

journal_title：Technology in cancer research & treatment

authors： Maiwand MO,Asimakopoulos G

更新日期：2004-04-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to compare the prognostic value of the percentage of positive biopsy cores (PPBC), the percentage of cancer volume (PCV), and the maximum involvement of biopsy cores (MIBC) as a prognostic factor in low- and intermediate-risk patients with clinically localized prostate cancer wh...

journal_title：Technology in cancer research & treatment

authors： Slater JM,Bush DA,Grove R,Slater JD

更新日期：2014-06-01 00:00:00

abstract：:Circular RNAs are a recently discovered subclass of endogenous noncoding RNAs that have been confirmed to play an important role in various pathophysiological processes. However, the underlying function of circular RNAs in osteosarcoma still remains unclear. We aimed to comprehend the function of circ_0032462 in osteo...

journal_title：Technology in cancer research & treatment

authors： Gu R,Li X,Yan X,Feng Z,Hu A

更新日期：2020-01-01 00:00:00

abstract：:Hepatocellular carcinoma is the fourth leading cause of cancer-related death worldwide. Depending on the extent of disease and competing comorbidities for mortality, multiple liver-directed therapy options exist for the treatment of hepatocellular carcinoma. Advancements in radiation oncology have led to the emergence...

journal_title：Technology in cancer research & treatment

authors： Schaub SK,Hartvigson PE,Lock MI,Høyer M,Brunner TB,Cardenes HR,Dawson LA,Kim EY,Mayr NA,Lo SS,Apisarnthanarax S

更新日期：2018-01-01 00:00:00

abstract：:We investigated the technique, early results and toxicity of curative stereotactic radiotherapy with the CyberKnife (Accuray Incorporated, Sunnyvale, California, USA) in 15 extracranial, extrapulmonary, extrahepatic, and extraspinal tumors. Fourteen tumors were located close to the bowel or esophagus. The PTV = GTV + ...

journal_title：Technology in cancer research & treatment

authors： Nuyttens JJ,Prevost JB,Van der Voort van Zijp NC,Hoogeman M,Levendag PC

更新日期：2007-12-01 00:00:00