Novel advances in drug delivery to brain cancer.

abstract：PURPOSE:We recently developed a novel, open-source in vivo dosimetry that uses the electronic portal imaging device to detect dose delivery discrepancies. We applied our method on patients with rectal cancer treated on a belly board device. METHODS:In vivo dosimetry was performed on 10 patients with rectal cancer trea...

journal_title：Technology in cancer research & treatment

authors： Peca S,Sinha RS,Brown DW,Smith WL

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Tissue differentiation-inducing non-protein coding RNA (TINCR) has been shown to play a crucial role in pathogenesis of various types of human cancer including breast cancer (BC). The purpose of this study was to determine the potential prognostic value of serum lncRNA TINCR in BC. METHODS:Quantitative reve...

journal_title：Technology in cancer research & treatment

authors： Wang X,Li S,Xiao H,Deng X

更新日期：2020-01-01 00:00:00

abstract：:Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient studies been performed investigating the part of long noncoding R...

journal_title：Technology in cancer research & treatment

authors： Sun KK,Shen XJ,Yang D,Jiao Y,Wu XY

更新日期：2020-01-01 00:00:00

abstract：:At external beam radiotherapy, stereoscopic X-ray imaging system is responsible as tumor motion information provider. This system takes X-ray images intermittently from tumor position (1) at pretreatment step to provide training data set for model construction and (2) during treatment to control the accuracy of correl...

journal_title：Technology in cancer research & treatment

authors： Esmaili Torshabi A,Ghorbanzadeh L

更新日期：2017-04-01 00:00:00

abstract：:Routine follow-up visits and radiographic imaging are required for outcome evaluation and tumor recurrence monitoring. Yet more personalized surveillance is required in order to sufficiently address the nature of heterogeneity in nonsmall cell lung cancer and possible recurrences upon completion of treatment. Radiomic...

journal_title：Technology in cancer research & treatment

authors： Shi L,He Y,Yuan Z,Benedict S,Valicenti R,Qiu J,Rong Y

更新日期：2018-01-01 00:00:00

abstract：:We do not know the clinical and prognostic factors that influence the survival of patients with gastric signet ring cell carcinoma (SRC). Therefore, a retrospective review was undertaken of 219 patients with SRC who had undergone gastrectomy between January 2009 and December 2012 in our hospital. Patient age, sex, TNM...

journal_title：Technology in cancer research & treatment

authors： Yu JM,Zhan ZW,Zhen JX,Wang XJ,Chen Y,Lin J,Chen L,Chen LZ,Huang YF,Guo ZQ

更新日期：2020-01-01 00:00:00

abstract：:Ionizing radiation therapy is one of the primary modalities for treating cancers. Ideally, the particle selected to deliver ionizing radiation for routine therapy should control the disease, cause minimal side effects, and be affordable. Two major properties for judging the utility of a particle, physical controllabil...

journal_title：Technology in cancer research & treatment

authors： Slater JM

更新日期：2007-08-01 00:00:00

abstract：:A review of the literature on the current applications of breast magnetic resonance imaging (MRI) indications, their rationale and their place in diagnosis and management of breast cancer was given. Contrast-enhanced breast MRI is developing as a valuable adjunct to mammography and sonography. Its high sensitivity for...

journal_title：Technology in cancer research & treatment

authors： Pavic D,Koomen MA,Kuzmiak CM,Lee YH,Pisano ED

更新日期：2004-12-01 00:00:00

abstract：:Hydroxycamptothecin-encapsulated chitosan (HC) nanospheres were prepared by Shirasu porous glass (SPG) membrane emulsification technique. The properties and morphology of HC nanospheres were characterized. The diameter of the nanospheres could be controlled within a narrow distribution according to the pore-size of SP...

journal_title：Technology in cancer research & treatment

authors： Han J,Hou ZQ,Wang YG,Guo X

更新日期：2015-02-01 00:00:00

abstract：:Stereotactic radiosurgery (SRS) refers to a single radiation treatment delivering a high dose to an intra-cranial target localized in three-dimensions by CT and/or MRI imaging. Traditionally, immobilization of the patient's head has been achieved using a rigid stereotactic head frame as the key step in allowing for ac...

journal_title：Technology in cancer research & treatment

authors： Sahgal A,Ma L,Chang E,Shiu A,Larson DA,Laperriere N,Yin FF,Tsao M,Menard C,Basran P,Létourneau D,Heydarian M,Beachey D,Shukla V,Cusimano M,Hodaie M,Zadeh G,Bernstein M,Schwartz M

更新日期：2009-08-01 00:00:00

abstract：:Breast cancer remains one of the leading causes of cancer-associated death in women. MiR-27a is highly expressed in breast cancer tissue. However, the underlying mechanisms that promote breast cancer progression are unknown. In this study, we investigated the regulatory mechanisms of miR-27a and its target glycogen Sy...

journal_title：Technology in cancer research & treatment

authors： Chen H,Zhang Y,Cao X,Mou P

更新日期：2020-01-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to compare the prognostic value of the percentage of positive biopsy cores (PPBC), the percentage of cancer volume (PCV), and the maximum involvement of biopsy cores (MIBC) as a prognostic factor in low- and intermediate-risk patients with clinically localized prostate cancer wh...

journal_title：Technology in cancer research & treatment

authors： Slater JM,Bush DA,Grove R,Slater JD

更新日期：2014-06-01 00:00:00

abstract：:Human epidermal growth factor 2 (HER2)+ breast cancer is considered the most dangerous type of breast cancers. Herein, we used bioinformatics methods to identify potential key genes in HER2+ breast cancer to enable its diagnosis, treatment, and prognosis prediction. Datasets of HER2+ breast cancer and normal tissue sa...

journal_title：Technology in cancer research & treatment

authors： Weng Y,Liang W,Ji Y,Li Z,Jia R,Liang Y,Ning P,Xu Y

更新日期：2021-01-01 00:00:00

abstract：:The aim of this study was to evaluate the relationship of prognosis of patients with multiple myeloma having extramedullary involvement (EMM) with the 18F- fluorodeoxyglucose(18F-FDG) maximum standardized uptake value and the expression of Ki-67 in biopsy samples. Sixty-five patients were newly diagnosed with multiple...

journal_title：Technology in cancer research & treatment

authors： Li Q,Ma J,Li H,Xu W,Cao Z,Liu S,Chen L,Gao S,Yan T,Li D,Wang X,Yue Y,Zhao Z,Wang X,Yang H,Zhao H,Yu Y,Zhang Y,Fan F,Wang Y

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. MATERIALS AND METHODS:A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identi...

journal_title：Technology in cancer research & treatment

authors： Korpics M,Johnson P,Patel R,Surucu M,Choi M,Emami B,Roeske JC

更新日期：2016-12-01 00:00:00

abstract：:We previously showed that microRNA-182 (miR-182) might promote cell proliferation and migration in triple-negative breast cancer (TNBC). This study aimed to investigate circular RNAs (circRNAs) that interact with miR-182 and play important roles in TNBC. Thirty patients with TNBC were enrolled. One pair of tumor and a...

journal_title：Technology in cancer research & treatment

authors： Yu J,Shen W,Xu J,Gong B,Gao B,Zhu J

更新日期：2020-01-01 00:00:00

abstract：:To describe the technological background, the accuracy, and clinical feasibility for single session lung radiosurgery using a real-time robotic system with respiratory tracking. The latest version of image-guided real-time respiratory tracking software (Synchrony, Accuray Incorporated, Sunnyvale, CA) was applied and i...

journal_title：Technology in cancer research & treatment

authors： Muacevic A,Drexler C,Wowra B,Schweikard A,Schlaefer A,Hoffmann RT,Wilkowski R,Winter H,Reiser M

更新日期：2007-08-01 00:00:00

abstract：:Irreversible electroporation (IRE) has been shown to be an effective method of killing cells locally. In contrast to radiofrequency ablation, the mechanism by which cells are thought to die via IRE is the creation of pores in cell membranes, without substantial increase in tissue temperature. To determine the degree t...

journal_title：Technology in cancer research & treatment

authors： Long G,Bakos G,Shires PK,Gritter L,Crissman JW,Harris JL,Clymer JW

更新日期：2014-12-01 00:00:00

abstract：:The study of the effectiveness of cryotherapy as a curative treatment for prostate cancer has often relied on the use of either in vitro cell culture monolayers or animal models. While the data gleaned from these studies have been valuable, each model has inherent limitations. In order to bridge the gap between in vit...

journal_title：Technology in cancer research & treatment

authors： Robilotto AT,Clarke D,Baust JM,Van Buskirk RG,Gage AA,Baust JG

更新日期：2007-04-01 00:00:00

abstract：:The response of the tumor microvasculature to ionizing radiation can be modified to improve tumor control in preclinical mouse models of cancer. Recent studies have shown that a variety of cancer drugs can improve the response of cancers to radiotherapy. Protein tyrosine kinase inhibitors (TKIs) have been shown to enh...

journal_title：Technology in cancer research & treatment

authors： Lu B,Shinohara ET,Edwards E,Geng L,Tan J,Hallahan DE

更新日期：2005-12-01 00:00:00

abstract：:Poorly differentiated cell populations including tumor-initiating stem cells have been demonstrated to display a unique ability to natively internalize fragmented double-stranded DNA. Using this feature as a marker, we show that 0.1% to 6% of human glioblastoma cells from the bioptates can effectively internalize a fl...

journal_title：Technology in cancer research & treatment

authors： Dolgova EV,Mishinov SV,Proskurina AS,Potter EA,Efremov YR,Bayborodin SI,Tyrinova TV,Stupak VV,Ostatin AA,Chernykh ER,Bogachev SS

更新日期：2018-01-01 00:00:00

abstract：:Endometrial carcinoma is one of the most common cancers in women. A limited number of endometrial carcinoma cell lines are available for studies of signal transduction pathways and experimental therapeutics in vitro. However, these cell lines have not been comprehensively characterized. In this study, we used genome-w...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Yang D,Cogdell D,Hu L,Xue F,Broaddus R,Zhang W

更新日期：2010-04-01 00:00:00

abstract：:The purpose of this work is to estimate the degree of uncertainty inherent to a given four dimensional computed tomography (4D-CT) imaging modality and to test for interaction of the investigated factors (i.e., object displacement, velocity, and the period of motion) when determining the object motion coordinates, mot...

journal_title：Technology in cancer research & treatment

authors： Ehler E,Tome W

更新日期：2010-06-01 00:00:00

abstract：:The objective of this study is to compare the new and conventional tomotherapy treatment techniques and to evaluate dosimetric differences between them. A dosimetric analysis was performed by comparing planning target volume (PTV) median dose, 95% of PTV dose coverage, Paddick conformity index (CI), homogeneity index ...

journal_title：Technology in cancer research & treatment

authors： Zhang X,Penagaricano J,Han EY,Morrill S,Hardee M,Liang X,Gupta SK,Corry PM,Ratanatharathom V

更新日期：2015-08-01 00:00:00

abstract：:Spinal metastases are a common manifestation of malignant tumors that can cause severe pain, spinal cord compression, pathological fractures, and hypercalcemia, and these clinical manifestations will ultimately reduce the health-related quality of life and even shorten life expectancy in patient with cancer. Effective...

journal_title：Technology in cancer research & treatment

authors： Zhang HR,Li JK,Yang XG,Qiao RQ,Hu YC

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Gene expression profiles from early-onset breast cancer and normal tissues were analyzed to explore the genes and prognostic factors associated with breast cancer. METHODS:GSE109169 and GSE89116 were obtained from the database of Gene Expression Omnibus. We firstly screened the differentially expressed gene...

journal_title：Technology in cancer research & treatment

authors： Yu Z,He Q,Xu G

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Testicular cancer represents the most common malignancy in young adult men. In the current study, we sought to analyze and compare the prognostic value of lymph node ratio (LNR) as well as positive lymph node counts (LNC) to understand its clinical significance in testicular germ cell tumors. METHODS:We emp...

journal_title：Technology in cancer research & treatment

authors： Huang C,Long Q,Pan Y,Wu L,Wang X,Xu H,Zheng F

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:The efficacy of image-guided high-dose rate brachytherapy for cervical cancer is limited by the ineffective rectal sparing devices available commercially and the potential applicator movement. We developed a novel device using a balloon catheter and a belt immobilization system, serving for rectal dose reductio...

journal_title：Technology in cancer research & treatment

authors： Fan Q,Yeung AR,Amdur R,Helmig R,Park J,Li J,Kahler D,Liu C,Lu B

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND AIM:Methylated SEPT9 is a novel circulating tumor DNA marker for colorectal cancer, while the effects of various colorectal cancer clinicopathological factors on its detection performance have not been fully evaluated. This study aims to investigate the significance of the clinicopathological factors on ...

journal_title：Technology in cancer research & treatment

authors： He N,Song L,Kang Q,Jin P,Cai G,Zhou J,Zhou G,Sheng J,Cai S,Wang J,Han X,Nie Y,Wu K

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The incidence of nasopharyngeal carcinoma is increasing gradually, but the pathogenesis is not completely clear. MicroRNA, a highly conserved endogenous noncoding small molecule RNA, plays an essential role in the regulation of gene expression and is a hotspot in cancer research worldwide. OBJECTIVES:Althou...

journal_title：Technology in cancer research & treatment

authors： Xuefang Z,Ruinian Z,Liji J,Chun Z,Qiaolan Z,Jun J,Yuming C,Junrong H

更新日期：2020-01-01 00:00:00