Selecting the optimum particle for radiation therapy.

abstract：:Human epidermal growth factor 2 (HER2)+ breast cancer is considered the most dangerous type of breast cancers. Herein, we used bioinformatics methods to identify potential key genes in HER2+ breast cancer to enable its diagnosis, treatment, and prognosis prediction. Datasets of HER2+ breast cancer and normal tissue sa...

journal_title：Technology in cancer research & treatment

authors： Weng Y,Liang W,Ji Y,Li Z,Jia R,Liang Y,Ning P,Xu Y

更新日期：2021-01-01 00:00:00

abstract：:The efficacy of photodynamic therapy for the treatment of a large number of skin diseases, in particular non-malignant skin cancer, has been reported by a number of studies. It has been demonstrated to be particularly beneficial for large or multiple lesions, especially where good cosmesis is required. However for PDT...

journal_title：Technology in cancer research & treatment

authors： Kendall CA,Morton CA

更新日期：2003-08-01 00:00:00

abstract：:Blood flow is a key parameter in studying cancer angiogenesis and hypermetabolism. Current photoacoustic blood flow estimation methods focus on either the axial or transverse component of the flow vector. However, the Doppler angle (beam-to-flow angle) is needed to calculate the total flow speed, and it cannot always ...

journal_title：Technology in cancer research & treatment

authors： Yao J,Maslov KI,Wang LV

更新日期：2012-08-01 00:00:00

abstract：:Spinal metastases are a common manifestation of malignant tumors that can cause severe pain, spinal cord compression, pathological fractures, and hypercalcemia, and these clinical manifestations will ultimately reduce the health-related quality of life and even shorten life expectancy in patient with cancer. Effective...

journal_title：Technology in cancer research & treatment

authors： Zhang HR,Li JK,Yang XG,Qiao RQ,Hu YC

更新日期：2020-01-01 00:00:00

abstract：:We previously showed that microRNA-182 (miR-182) might promote cell proliferation and migration in triple-negative breast cancer (TNBC). This study aimed to investigate circular RNAs (circRNAs) that interact with miR-182 and play important roles in TNBC. Thirty patients with TNBC were enrolled. One pair of tumor and a...

journal_title：Technology in cancer research & treatment

authors： Yu J,Shen W,Xu J,Gong B,Gao B,Zhu J

更新日期：2020-01-01 00:00:00

abstract：:The accurate characterization and description of the vascular network of a cancer lesion is of paramount importance in clinical practice and cancer research in order to improve diagnostic accuracy or to assess the effectiveness of a treatment. The aim of this study was to show the effectiveness of liposomes as an ultr...

journal_title：Technology in cancer research & treatment

authors： Molinari F,Meiburger KM,Giustetto P,Rizzitelli S,Boffa C,Castano M,Terreno E

更新日期：2014-12-01 00:00:00

abstract：:Lung carcinoma is the most frequently diagnosed malignancy in the world, with the incidence increasing through the 20th century. Presentation may be as a tumor mass primarily obstructing the central bronchial lumen, or a mass infiltrating lung tissue. Cryosurgery can be used as a method of palliative treatment for bot...

journal_title：Technology in cancer research & treatment

authors： Maiwand MO,Asimakopoulos G

更新日期：2004-04-01 00:00:00

abstract：:This article proposes quantitative analysis tools and digital phantoms to quantify intrinsic errors of deformable image registration (DIR) systems and establish quality assurance (QA) procedures for clinical use of DIR systems utilizing local and global error analysis methods with clinically realistic digital image ph...

journal_title：Technology in cancer research & treatment

authors： Kim H,Park SB,Monroe JI,Traughber BJ,Zheng Y,Lo SS,Yao M,Mansur D,Ellis R,Machtay M,Sohn JW

更新日期：2015-08-01 00:00:00

abstract：:Endometrial carcinoma is one of the most common cancers in women. A limited number of endometrial carcinoma cell lines are available for studies of signal transduction pathways and experimental therapeutics in vitro. However, these cell lines have not been comprehensively characterized. In this study, we used genome-w...

journal_title：Technology in cancer research & treatment

authors： Wang Y,Yang D,Cogdell D,Hu L,Xue F,Broaddus R,Zhang W

更新日期：2010-04-01 00:00:00

abstract：:Tumor-infiltrating immune cells are part of a complex microenvironment and associated with improved clinical outcomes in a broad range of tumor types. However, a detailed map for the prognostic landscape of tumor-infiltrating immune cells and immune checkpoint modulators in glioblastoma is still lacking. Here, with th...

journal_title：Technology in cancer research & treatment

authors： Wu S,Yang W,Zhang H,Ren Y,Fang Z,Yuan C,Yao Z

更新日期：2019-01-01 00:00:00

abstract：:Chemo-radiotherapy is standard treatment of stage IIIA-N2 bulky or IIIB non-small cell lung cancer (NSCLC). Surgical resection of residual disease in downstaged patients may improve overall survival. In this setting, restaging disease is still a challenge. 18F-FDG PET/CT represents the gold standard although accuracy ...

journal_title：Technology in cancer research & treatment

authors： Genestreti G,Burgio MA,Matteucci F,Piciucchi S,Scarpi E,Monti M,Bucchi L,Parisi E,Crociani L,Gurioli C,Poletti V,Gavelli G

更新日期：2015-12-01 00:00:00

abstract：:Hepatocellular carcinoma is the fourth leading cause of cancer-related death worldwide. Depending on the extent of disease and competing comorbidities for mortality, multiple liver-directed therapy options exist for the treatment of hepatocellular carcinoma. Advancements in radiation oncology have led to the emergence...

journal_title：Technology in cancer research & treatment

authors： Schaub SK,Hartvigson PE,Lock MI,Høyer M,Brunner TB,Cardenes HR,Dawson LA,Kim EY,Mayr NA,Lo SS,Apisarnthanarax S

更新日期：2018-01-01 00:00:00

abstract：:Positron emission tomography (PET), the imaging of pharmaceuticals labeled with positron-emitting radionuclides, is a rapidly growing modality for the diagnosis and management of cancer. PET yields high-quality images characterizing substrate metabolism, cellular proliferation, receptor density, and other parameters t...

journal_title：Technology in cancer research & treatment

authors： Mandelkern M,Raines J

更新日期：2002-12-01 00:00:00

abstract：:Tumstatin (Tum) is a powerful angiostatin that inhibits proliferation and induces apoptosis of tumorous vascular endothelial cells. A nonpathogenic and anaerobic bacterium, Bifidobacterium longum (BL), selectively localizes to and proliferates in the hypoxia location within solid tumor. The aims of this study were to ...

journal_title：Technology in cancer research & treatment

authors： Wei C,Xun AY,Wei XX,Yao J,Wang JY,Shi RY,Yang GH,Li YX,Xu ZL,Lai MG,Zhang R,Wang LS,Zeng WS

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:Acute myeloid leukemia (AML) represents a hematological cancer. The aim of the investigation was to probe the regulatory relevance of long non-coding RNA (lncRNA) aspartyl-tRNA synthetase anti-sense 1 (DARS-AS1)/microRNA-425 (miR-425)/transforming growth factor-beta 1 (TGFB1) to the development of AML. METHO...

journal_title：Technology in cancer research & treatment

authors： Dou B,Jiang Z,Chen X,Wang C,Wu J,An J,Sheng G

更新日期：2020-01-01 00:00:00

abstract：:The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C(60)(OH)(24) in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Experiment was performed on adult female Spra...

journal_title：Technology in cancer research & treatment

authors： Injac R,Perse M,Boskovic M,Djordjevic-Milic V,Djordjevic A,Hvala A,Cerar A,Strukelj B

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:To test the feasibility of modified biopsy needles as probes for irreversible electroporation ablation and periprocedural biopsy. METHODS:Core biopsy needles of 16-G/9-cm were customized to serve as experimental ablation probes. Computed tomography-guided percutaneous irreversible electroporation was perfor...

journal_title：Technology in cancer research & treatment

authors： Wimmer T,Srimathveeravalli G,Silk M,Monette S,Gutta N,Maybody M,Erinjery JP,Coleman JA,Solomon SB,Sofocleous CT

更新日期：2016-12-01 00:00:00

abstract：:The therapy of brain tumors has been limited by a lack of effective methods of drug delivery to the brain. Systemic administration is often associated with toxic side effects and ultimately fails to achieve therapeutic concentrations within a tumor. An attractive strategy that has gained importance in brain tumor ther...

journal_title：Technology in cancer research & treatment

authors： Lesniak MS

更新日期：2005-08-01 00:00:00

abstract：:Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient studies been performed investigating the part of long noncoding R...

journal_title：Technology in cancer research & treatment

authors： Sun KK,Shen XJ,Yang D,Jiao Y,Wu XY

更新日期：2020-01-01 00:00:00

abstract：:Complement 3a (C3a) and complement 5a (C5a), small cleavage fragments generated by complement activation, has been previously shown to be obviously up-regulated in highly metastatic hepatocellular carcinoma (HCC) cells. However, their functional roles in HCC cells remains unclear. Here, we investigated the biological ...

journal_title：Technology in cancer research & treatment

authors： Chen B,Zhou W,Tang C,Wang G,Yuan P,Zhang Y,Bhushan SC,Ma J,Leng J

更新日期：2020-01-01 00:00:00

abstract：:Volumetric modulated arc therapy (VMAT) has been adopted by many clinics for its higher delivery efficiency compared to conventional intensity modulated radiotherapy techniques. Currently, the quality assurance (QA) has remained a challenge in that no identical tests are available for accelerators from different vendo...

journal_title：Technology in cancer research & treatment

authors： Wang J,Hu W,Peng J,Lu S,Zhao J,Xiao Y,Zhang Z

更新日期：2015-08-01 00:00:00

abstract：:Fascin is overexpressed in various tumor tissues and is closely related to tumor metastasis and invasion. However, the role of fascin in cholangiocarcinoma RBE cells has not been clearly reported. This study aimed to establish a cholangiocarcinoma cell line with stable and high expression of fascin to observe the effe...

journal_title：Technology in cancer research & treatment

authors： Zhao H,Yang F,Zhao W,Zhang C,Liu J

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:In this study, we aimed to evaluate the prognostic value of fluorodeoxyglucose uptake in the lung parenchyma and the presence of subclinical interstitial lung disease on computed tomography as predictive factors for survival following stereotactic body radiation therapy in patients with stage I non-small cell l...

journal_title：Technology in cancer research & treatment

authors： Satoh Y,Motosugi U,Saito A,Omiya Y,Onishi H

更新日期：2018-01-01 00:00:00

abstract：:Since "Warburg effect" has been firstly uncovered in cancer cells in 1956, mounting evidence has supported the molecular mechanism underlying the energy metabolism in induced chemoresistance in cancers. MicroRNAs can mediate fine-tuning of genes in physiological process. MicroRNAs' energy metabolic role in chemoresist...

journal_title：Technology in cancer research & treatment

authors： Ye J,Zou M,Li P,Liu H

更新日期：2018-01-01 00:00:00

abstract：:MicroRNAs are reported as a vital important factor in cancer cell initiation and progression processes. MicroRNA-19-3p has drawn the attention of many researchers in recent years because of its wide expression and its key role in serious kinds of tumor cells. However, the detailed mechanism of microRNA-19a-3p in these...

journal_title：Technology in cancer research & treatment

authors： Su YF,Zang YF,Wang YH,Ding YL

更新日期：2020-01-01 00:00:00

abstract：:The use of electric pulses to transfect cells has recently been extended to show the utility of this procedure in vivo. Electrotransfer has been performed in vivo on several tissue types including skin, blood vessels, liver, tumor, muscle, cornea, brain and spleen. The most widely targeted tissue has been skeletal mus...

journal_title：Technology in cancer research & treatment

authors： Scherman D,Bigey P,Bureau MF

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To investigate the role of intensity-modulated proton therapy (IMPT) for hepatocellular carcinoma (HCC) patients to be treated with stereotactic body radiation therapy (SBRT) in a risk-adapted dose prescription regimen. METHODS:A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escala...

journal_title：Technology in cancer research & treatment

authors： Cozzi L,Comito T,Loi M,Fogliata A,Franzese C,Franceschini D,Clerici E,Reggiori G,Tomatis S,Scorsetti M

更新日期：2020-01-01 00:00:00

abstract：:Most experimental studies of electroporation focus on permeabilization of the outer cell membrane. Some experiments address delivery of ions and molecules into cells that should survive; others focus on efficient killing of the cells with minimal temperature rise. A basic method for quantifying electroporation effecti...

journal_title：Technology in cancer research & treatment

authors： Sweeney DC,Weaver JC,Davalos RV

更新日期：2018-01-01 00:00:00

abstract：:The incidence of optic neuropathy after stereotactic radiosurgery (SRS) is related to the total dose, fraction size, and treatment volume. Theoretically, fractionated SRS can decrease this risk. In this paper, we report our technique for fractionated SRS and assess its potential role in the management of tumors locate...

journal_title：Technology in cancer research & treatment

authors： Mehta VK,Lee QT,Chang SD,Cherney S,Adler JR Jr

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:The incidence of nasopharyngeal carcinoma is increasing gradually, but the pathogenesis is not completely clear. MicroRNA, a highly conserved endogenous noncoding small molecule RNA, plays an essential role in the regulation of gene expression and is a hotspot in cancer research worldwide. OBJECTIVES:Althou...

journal_title：Technology in cancer research & treatment

authors： Xuefang Z,Ruinian Z,Liji J,Chun Z,Qiaolan Z,Jun J,Yuming C,Junrong H

更新日期：2020-01-01 00:00:00