Endobronchial/Endoesophageal Ultrasound (EBUS/EUS) Guided Fine Needle Aspiration (FNA) and 18F-FDG PET/CT Scanning in Restaging of Locally Advanced Non-small Cell Lung Cancer (NSCLC) Treated with Chemo-radiotherapy: A Mono-institutional Pilot Experience.

abstract：OBJECTIVE:We compared radiotherapy plans among helical tomotherapy (HT), volumetric-modulated arc therapy (VMAT), and intensity-modulated proton therapy (IMPT) for angiosarcoma of the scalp (AS). METHODS:We conducted a planning study for 19 patients with AS. The clinical target volume (CTV) 1 and CTV2 were defined as ...

journal_title：Technology in cancer research & treatment

authors： Mizuno T,Tomita N,Takaoka T,Tomida M,Fukuma H,Tsuchiya T,Shibamoto Y

更新日期：2021-01-01 00:00:00

abstract：:Many conventional chemotherapeutic drugs, as well as DNA for cancer gene therapy, require efficient access to the cell interior to be effective. The cell membrane is a formidable barrier to many of these drugs, including therapeutic DNA constructs. Electropermeabilization (EP, often used synonymously with "electropora...

journal_title：Technology in cancer research & treatment

authors： Rabussay DP,Nanda GS,Goldfarb PM

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Circulating tumor cells (CTCs) hold huge potential for both clinical applications and basic research into the management of cancer, but the relationship between CTC count and cervical cancer prognosis remains unclear. Therefore, research on this topic is urgently required. OBJECTIVE:This study investigated ...

journal_title：Technology in cancer research & treatment

authors： Du K,Huang Q,Bu J,Zhou J,Huang Z,Li J

更新日期：2020-01-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) and Protein kinase B (PKB/Akt) play a crucial role in the formation of many malignant tumors and have been shown to be the important therapeutic targets. In the present study, we examined immunohistochemical expression of phosphorylated Akt (p-Akt) and COX-2 in 45 gastric adenocarcinomas with ...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Zhang QY,Fu YC,Wang T,Zhang J,Xu P,Zhou X,Pu PY,Kang CS

更新日期：2009-12-01 00:00:00

abstract：:In recent years, the imaging of drug-induced apoptosis has become one of the centers of interest in experimental and clinical research. In particular, the accurate monitoring of chemosensitivity as well as the early prediction of chemoresistance in response to various pro-apoptotic interventions are critical requireme...

journal_title：Technology in cancer research & treatment

authors： Belhocine T,Steinmetz N,Li C,Green A,Blankenberg FG

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:The main objective in studying large-scale cancer omics is to identify molecular mechanisms of cancer and discover novel biomedical targets. This work not only discovers the cancer subtypes in genome scale data by using clustering and classification but also measures their accuracy. METHODS:Initially, candid...

journal_title：Technology in cancer research & treatment

authors： Vasudevan P,Murugesan T

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:In this study, we aimed to evaluate the prognostic value of fluorodeoxyglucose uptake in the lung parenchyma and the presence of subclinical interstitial lung disease on computed tomography as predictive factors for survival following stereotactic body radiation therapy in patients with stage I non-small cell l...

journal_title：Technology in cancer research & treatment

authors： Satoh Y,Motosugi U,Saito A,Omiya Y,Onishi H

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Testicular cancer represents the most common malignancy in young adult men. In the current study, we sought to analyze and compare the prognostic value of lymph node ratio (LNR) as well as positive lymph node counts (LNC) to understand its clinical significance in testicular germ cell tumors. METHODS:We emp...

journal_title：Technology in cancer research & treatment

authors： Huang C,Long Q,Pan Y,Wu L,Wang X,Xu H,Zheng F

更新日期：2021-01-01 00:00:00

abstract：:The microRNA-200 (miR-200) family has been reported to be vital for the inhibition of epithelial-to-mesenchymal transition (EMT) in tumor cells. The miR-200 family represents a complex multi-factorial regulatory network which has not been well described in breast cancer. This study aimed to clarify the underlying regu...

journal_title：Technology in cancer research & treatment

authors： Zhang J,Shao N,Yang X,Xie C,Shi Y,Lin Y

更新日期：2020-01-01 00:00:00

abstract：:We have developed a small animal conformal radiation therapy device that provides a degree of geometrical/anatomical targeting comparable to what is achievable in a commercial animal irradiator. small animal conformal radiation therapy device is capable of producing precise and accurate conformal delivery of radiation...

journal_title：Technology in cancer research & treatment

authors： Sharma S,Narayanasamy G,Przybyla B,Webber J,Boerma M,Clarkson R,Moros EG,Corry PM,Griffin RJ

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:To test the feasibility of modified biopsy needles as probes for irreversible electroporation ablation and periprocedural biopsy. METHODS:Core biopsy needles of 16-G/9-cm were customized to serve as experimental ablation probes. Computed tomography-guided percutaneous irreversible electroporation was perfor...

journal_title：Technology in cancer research & treatment

authors： Wimmer T,Srimathveeravalli G,Silk M,Monette S,Gutta N,Maybody M,Erinjery JP,Coleman JA,Solomon SB,Sofocleous CT

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Antibody resistance, both de novo and acquired, is usually related to high risk of recurrence and lower survival rate in gynecologic cancers. Prevention or reversal of the resistance often yields beneficial clinical results. It was reported that anti-human epidermal growth factor receptor 3 monoclonal antibo...

journal_title：Technology in cancer research & treatment

authors： Li X,Duan Y,Qiao C,Zhou T,Yu M,Geng J,Feng J,Shen B,Lv M,Li Y

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To evaluate 2 simultaneous integrated boost treatment planning techniques using helical tomotherapy for breast conserving therapy with regard to acute skin toxicity and dosimetry. METHODS:Thirty-two patients were studied. The original approach was for 16 patients and incorporated a directional block of the ips...

journal_title：Technology in cancer research & treatment

authors： Wojcieszynski AP,Olson AK,Rong Y,Kimple RJ,Yadav P

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Palliation of advanced disease using radiotherapy can create difficult clinical situations where standard computed tomography simulation and immobilization techniques are not feasible. We developed a linear accelerator-based radiotherapy simulation technique using nonstandard patient positioning for head and...

journal_title：Technology in cancer research & treatment

authors： Dyer BA,Nair CK,Deardorff CE,Wright CL,Perks JR,Rao SS

更新日期：2019-01-01 00:00:00

abstract：:The use of electric pulses to transfect cells has recently been extended to show the utility of this procedure in vivo. Electrotransfer has been performed in vivo on several tissue types including skin, blood vessels, liver, tumor, muscle, cornea, brain and spleen. The most widely targeted tissue has been skeletal mus...

journal_title：Technology in cancer research & treatment

authors： Scherman D,Bigey P,Bureau MF

更新日期：2002-10-01 00:00:00

abstract：:Breast cancer remains one of the leading causes of cancer-associated death in women. MiR-27a is highly expressed in breast cancer tissue. However, the underlying mechanisms that promote breast cancer progression are unknown. In this study, we investigated the regulatory mechanisms of miR-27a and its target glycogen Sy...

journal_title：Technology in cancer research & treatment

authors： Chen H,Zhang Y,Cao X,Mou P

更新日期：2020-01-01 00:00:00

abstract：:Poorly differentiated cell populations including tumor-initiating stem cells have been demonstrated to display a unique ability to natively internalize fragmented double-stranded DNA. Using this feature as a marker, we show that 0.1% to 6% of human glioblastoma cells from the bioptates can effectively internalize a fl...

journal_title：Technology in cancer research & treatment

authors： Dolgova EV,Mishinov SV,Proskurina AS,Potter EA,Efremov YR,Bayborodin SI,Tyrinova TV,Stupak VV,Ostatin AA,Chernykh ER,Bogachev SS

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:The aim of the in vivo dosimetry, during the fractionated radiation therapy, is the verification of the correct dose delivery to patient. Nowadays, in vivo dosimetry procedures for photon beams are based on the use of the electronic portal imaging device and dedicated software to elaborate electronic portal ima...

journal_title：Technology in cancer research & treatment

authors： Falco MD,Giancaterino S,De Nicola A,Adorante N,De Lorenzo RG,Di Tommaso M,Vinciguerra A,Trignani M,Perrotti F,Allajbej A,Fidanzio A,Greco F,Grusio M,Genovesi D,Piermattei A

更新日期：2018-01-01 00:00:00

abstract：:Irreversible electroporation (IRE) has been shown to be an effective method of killing cells locally. In contrast to radiofrequency ablation, the mechanism by which cells are thought to die via IRE is the creation of pores in cell membranes, without substantial increase in tissue temperature. To determine the degree t...

journal_title：Technology in cancer research & treatment

authors： Long G,Bakos G,Shires PK,Gritter L,Crissman JW,Harris JL,Clymer JW

更新日期：2014-12-01 00:00:00

abstract：:Radiotherapy is frequently indicated to treat cerebral gliomas. Accurate response evaluation after radiotherapy is essential to determine the efficacy of treatment. We retrospectively analyzed the volumetric tumor response after simultaneous integrated boost-intensity modulated radiotherapy (SIB-IMRT) in patients with...

journal_title：Technology in cancer research & treatment

authors： Cho KH,Choi JH,Kim JY,Lee SH,Yoo H,Shin KH,Kim TH,Moon SH,Lee SH,Park HC

更新日期：2012-02-01 00:00:00

abstract：AIM:To explore the relationship of clinicopathological features and the proteins of C-met expression in the prognosis of cholangiocarcinoma. METHODS:Clinical data and the completed follow-up information of patients with cholangiocarcinoma who underwent cholangiocarcinoma operation from January 2004 to December 2010 we...

journal_title：Technology in cancer research & treatment

authors： Mao ZY,Zhu GQ,Ren L,Guo XC,Su D,Bai L

更新日期：2016-04-01 00:00:00

abstract：:Optical methods such as reflectance and fluorescence spectroscopy are being investigated for their potential to aid cancer detection in a quantitative, minimally invasive manner. Mathematical models of reflectance and fluorescence provide an important link between measured optical data and biomedically-relevant tissue...

journal_title：Technology in cancer research & treatment

authors： Wilson RH,Mycek MA

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:To develop and evaluate an automatic intensity-modulated radiation therapy (IMRT) program for cervical cancer, including a Convolution Neural Network (CNN)-based prediction model and an automated optimization strategy. METHODS:A CNN deep learning model was trained to predict a patient-specify set of IMRT objec...

journal_title：Technology in cancer research & treatment

authors： Jihong C,Penggang B,Xiuchun Z,Kaiqiang C,Wenjuan C,Yitao D,Jiewei Q,Kerun Q,Jing Z,Tianming W

更新日期：2020-01-01 00:00:00

abstract：:Helical tomotherapy is a form of image-guided intensity-modulated radiotherapy that introduces the ring gantry concept into radiation oncology. The system is a combination of a therapeutic linear accelerator and a megavoltage CT-scanner. This work describes the clinical experience with megavoltage CT with 456 patients...

journal_title：Technology in cancer research & treatment

authors： Sterzing F,Kalz J,Sroka-Perez G,Schubert K,Bischof M,Roder F,Debus J,Herfarth K

更新日期：2009-10-01 00:00:00

abstract：:Two noninvasive methods, thermography and laser Doppler imaging (LDI), were assessed for their ability to quantitatively assess parameters of vascularity in lesions of HIV-associated Kaposi's sarcoma (KS). Thermography and LDI images of a representative KS lesion were recorded in 16 patients and compared to normal ski...

journal_title：Technology in cancer research & treatment

authors： Hassan M,Little RF,Vogel A,Aleman K,Wyvill K,Yarchoan R,Gandjbakhche AH

更新日期：2004-10-01 00:00:00

abstract：:Hepatocellular carcinoma is the fourth leading cause of cancer-related death worldwide. Depending on the extent of disease and competing comorbidities for mortality, multiple liver-directed therapy options exist for the treatment of hepatocellular carcinoma. Advancements in radiation oncology have led to the emergence...

journal_title：Technology in cancer research & treatment

authors： Schaub SK,Hartvigson PE,Lock MI,Høyer M,Brunner TB,Cardenes HR,Dawson LA,Kim EY,Mayr NA,Lo SS,Apisarnthanarax S

更新日期：2018-01-01 00:00:00

abstract：:This study quantifies the setup uncertainties to optimize the planning target volume (PTV) margin based on daily image guidance, its dosimetric impact, and radiobiological implication for intensity-modulated radiation therapy (IMRT) in head and neck cancer. Ten patients were retrospectively chosen who had been treated...

journal_title：Technology in cancer research & treatment

authors： Srivastava SP,Cheng CW,Das IJ

更新日期：2016-02-01 00:00:00

abstract：:A 51 year old male with a history of right facial numbness developed progressive upper lip swelling for one year, but an MRI of the head was unremarkable. A wide local excision of the upper lip was performed and pathology revealed a 1.7 cm mass, poorly differentiated squamous cell carcinoma with perineural invasion. S...

journal_title：Technology in cancer research & treatment

authors： Bhatnagar AK,Heron DE,Schaitkin B

更新日期：2005-06-01 00:00:00

abstract：:Non-thermal irreversible electroporation (N-TIRE) has shown promise as an ablative therapy for a variety of soft-tissue neoplasms. Here we describe the therapeutic planning aspects and first clinical application of N-TIRE for the treatment of an inoperable, spontaneous malignant intracranial glioma in a canine patient...

journal_title：Technology in cancer research & treatment

authors： Garcia PA,Pancotto T,Rossmeisl JH Jr,Henao-Guerrero N,Gustafson NR,Daniel GB,Robertson JL,Ellis TL,Davalos RV

更新日期：2011-02-01 00:00:00

abstract：:The accurate characterization and description of the vascular network of a cancer lesion is of paramount importance in clinical practice and cancer research in order to improve diagnostic accuracy or to assess the effectiveness of a treatment. The aim of this study was to show the effectiveness of liposomes as an ultr...

journal_title：Technology in cancer research & treatment

authors： Molinari F,Meiburger KM,Giustetto P,Rizzitelli S,Boffa C,Castano M,Terreno E

更新日期：2014-12-01 00:00:00