On correlated sources of uncertainty in four dimensional computed tomography data sets.

abstract：:The purpose of this study was to evaluate the feasibility and treatment plans of intensity-modulated radiation therapy using helical tomotherapy (HT) for brain metastases. Twenty-three patients with 1 to 4 brain metastases were treated with HT. In combination with whole-brain radiotherapy (simultaneous plans), metasta...

journal_title：Technology in cancer research & treatment

authors： Tomita N,Kodaira T,Tachibana H,Nakamura T,Nakahara R,Inokuchi H,Shibamoto Y

更新日期：2008-12-01 00:00:00

abstract：:Breast cancer remains one of the leading causes of cancer-associated death in women. MiR-27a is highly expressed in breast cancer tissue. However, the underlying mechanisms that promote breast cancer progression are unknown. In this study, we investigated the regulatory mechanisms of miR-27a and its target glycogen Sy...

journal_title：Technology in cancer research & treatment

authors： Chen H,Zhang Y,Cao X,Mou P

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. MATERIALS AND METHODS:A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identi...

journal_title：Technology in cancer research & treatment

authors： Korpics M,Johnson P,Patel R,Surucu M,Choi M,Emami B,Roeske JC

更新日期：2016-12-01 00:00:00

abstract：:The efficacy of photodynamic therapy for the treatment of a large number of skin diseases, in particular non-malignant skin cancer, has been reported by a number of studies. It has been demonstrated to be particularly beneficial for large or multiple lesions, especially where good cosmesis is required. However for PDT...

journal_title：Technology in cancer research & treatment

authors： Kendall CA,Morton CA

更新日期：2003-08-01 00:00:00

abstract：:We attempted to characterize the cellular autofluorescence phenomenon of living HL-60 cells and to appraise its modifications under oxidative stress conditions induced by 1 alpha,25(OH)(2)D(3) (VD(3)) and its analog EB1089. Autofluorescence emission spectra of human promyelocytic HL-60 leukemic cells were monitored us...

journal_title：Technology in cancer research & treatment

authors： Bondza-Kibangou P,Millot C,Dufer J,Millot JM

更新日期：2004-08-01 00:00:00

abstract：:Optical mammography is one of several new techniques for breast cancer detection and characterization presently under development for clinical use that provide information other than morphologic, in particular on the biochemical and metabolic state of normal and diseased tissue. In breast tissue, scattering of red to ...

journal_title：Technology in cancer research & treatment

authors： Rinneberg H,Grosenick D,Moesta KT,Mucke J,Gebauer B,Stroszczynski C,Wabnitz H,Moeller M,Wassermann B,Schlag PM

更新日期：2005-10-01 00:00:00

abstract：:Endoscopic endonasal surgery (EES) has been shown to be a feasible approach to cranial base tumors while reducing post-operative morbidity. Using the endoscopic endonasal approach alone or in combination with open approaches may provide advantages over conventional approaches. However, the balance between maximal rese...

journal_title：Technology in cancer research & treatment

authors： Paravati AJ,Heron DE,Gardner PA,Snyderman C,Ozhasoglu C,Quinn A,Burton SA,Seelman K,Mintz AH

更新日期：2010-10-01 00:00:00

abstract：:The aim of this retrospective study is to evaluate our therapeutic results in patients with paranasal sinus (PNS) or nasal cavity (NC) malignancies treated with robotic stereotactic radiosurgery (SRS). Between August 2007 and October 2008, 27 patients with PNS or NC tumors were treated in our department using SRS. Med...

journal_title：Technology in cancer research & treatment

authors： Ozyigit G,Cengiz M,Hurmuz P,Yazici G,Gultekin M,Akyol F,Yildiz F,Gurkaynak M,Zorlu F

更新日期：2014-10-01 00:00:00

abstract：:We retrospectively reviewed factors that affected overall survival for patients with gynecological cancers that had metastasized to the brain. Between January 1985 to November 1999, we treated 25 patients with brain metastases from gynecological malignancies (cervix n=6, endometrium n=10, and ovary n=9). Various patie...

journal_title：Technology in cancer research & treatment

authors： Mahmoud-Ahmed AS,Kupelian PA,Reddy CA,Suh JH

更新日期：2002-08-01 00:00:00

abstract：:The inhibitor of growth (ING) family proteins have been defined as candidate tumor suppressors. ING4 as a novel member of ING family has potential tumor-suppressive effects via multiple pathways. However, the therapeutic effect of adenovirus-mediated ING4 (Ad-ING4) gene transfer in human osteosarcoma is still unknown....

journal_title：Technology in cancer research & treatment

authors： Xu M,Xie Y,Sheng W,Miao J,Yang J

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:The aim of the in vivo dosimetry, during the fractionated radiation therapy, is the verification of the correct dose delivery to patient. Nowadays, in vivo dosimetry procedures for photon beams are based on the use of the electronic portal imaging device and dedicated software to elaborate electronic portal ima...

journal_title：Technology in cancer research & treatment

authors： Falco MD,Giancaterino S,De Nicola A,Adorante N,De Lorenzo RG,Di Tommaso M,Vinciguerra A,Trignani M,Perrotti F,Allajbej A,Fidanzio A,Greco F,Grusio M,Genovesi D,Piermattei A

更新日期：2018-01-01 00:00:00

abstract：:Despite remarkable progress in diagnosis and treatment, malignant glioma, a highly lethal cancer of the central nervous system, remains incurable. Although glioma stem-like cells (GSCs) represent a relatively small fraction of the cells in malignant glioma, they can proliferate and self renew extensively, being crucia...

journal_title：Technology in cancer research & treatment

authors： Xu ZY,Li XQ,Chen S,Cheng Y,Deng JM,Wang ZG

更新日期：2012-12-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most aggressive type of gastrointestinal tumor, with a high rate of mortality. However, identifying biomarkers for the treatment of HCC remains to be developed. We aimed to determine whether cell division cycle 25C (CDC25C) could be used as a novel diagnostic and therapeutic bioma...

journal_title：Technology in cancer research & treatment

authors： Xun R,Lu H,Wang X

更新日期：2020-01-01 00:00:00

abstract：:Mesenchymal stromal cells are proven to be likely induce the angiogenic response in multiple myeloma and thus represent an enticing target for antiangiogenesis therapies for multiple myeloma. Substantial evidence indicates that angiogenesis in multiple myeloma is complex and involves direct production of angiogenic cy...

journal_title：Technology in cancer research & treatment

authors： Zhang X,Xu Y,Liu H,Zhao P,Chen Y,Yue Z,Zhang Z,Wang X

更新日期：2018-01-01 00:00:00

abstract：:The increasing evidence supported the role of Enhancer of Zeste Homolog 2 (EZH2) in the cancer development and progression. However, its precise role in the tumorigenesis of Nasopharyngeal Carcinoma (NPC) remains to be elucidated. EZH2 was depleted by retroviral infection in the NPC cells (HK-1, CNE-2, CNE-1 and C666-...

journal_title：Technology in cancer research & treatment

authors： Zhong J,Min L,Huang H,Li L,Li D,Li J,Ma Z,Dai L

更新日期：2013-06-01 00:00:00

abstract：:The aim of this paper is to study the feasibility for determining the individual internal target volume (ITV) for hepatocellular carcinoma (HCC) using 3DCT associated with active breathing coordinator (ABC), comparing the ITVs defined by 3DCT associated with ABC and 4DCT. Thirteen patients with HCC after transarterial...

journal_title：Technology in cancer research & treatment

authors： Gong G,Yin Y,Xing L,Guo Y,Chen J,Liu T,Lu J,Ma C,Sun T,Bai T,Zhang G,Deng W

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The biological function of deoxycytidine kinase in tumor is not yet clear, and there are a few studies relating to the correlation of deoxycytidine kinase gene with the occurrence and development of liver cancer. METHODS:The messenger RNA expression of deoxycytidine kinase was analyzed with the use of the U...

journal_title：Technology in cancer research & treatment

authors： Hu SF,Lin X,Xu LP,Chen HG,Guo JF,Jin L

更新日期：2020-01-01 00:00:00

abstract：:Routine follow-up visits and radiographic imaging are required for outcome evaluation and tumor recurrence monitoring. Yet more personalized surveillance is required in order to sufficiently address the nature of heterogeneity in nonsmall cell lung cancer and possible recurrences upon completion of treatment. Radiomic...

journal_title：Technology in cancer research & treatment

authors： Shi L,He Y,Yuan Z,Benedict S,Valicenti R,Qiu J,Rong Y

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Antibody resistance, both de novo and acquired, is usually related to high risk of recurrence and lower survival rate in gynecologic cancers. Prevention or reversal of the resistance often yields beneficial clinical results. It was reported that anti-human epidermal growth factor receptor 3 monoclonal antibo...

journal_title：Technology in cancer research & treatment

authors： Li X,Duan Y,Qiao C,Zhou T,Yu M,Geng J,Feng J,Shen B,Lv M,Li Y

更新日期：2016-08-01 00:00:00

abstract：:Many conventional chemotherapeutic drugs, as well as DNA for cancer gene therapy, require efficient access to the cell interior to be effective. The cell membrane is a formidable barrier to many of these drugs, including therapeutic DNA constructs. Electropermeabilization (EP, often used synonymously with "electropora...

journal_title：Technology in cancer research & treatment

authors： Rabussay DP,Nanda GS,Goldfarb PM

更新日期：2002-02-01 00:00:00

abstract：:The coupling mechanism between neuronal firing and cerebrovascular dilatation can be significantly compromised in cerebral diseases, making it difficult to identify eloquent cortical areas near or within resectable lesions by using Blood Oxygen Level Dependent (BOLD) fMRI. Several metabolic and vascular factors have ...

journal_title：Technology in cancer research & treatment

authors： Pillai JJ,Zacà D

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:To assess the efficacy of stereotactic body radiotherapy in patients with unresectable locally advanced pancreatic cancer. MATERIALS AND METHODS:All patients received a prescription dose of 45 Gy in 6 fractions. Primary end point was freedom from local progression. Secondary end points were overall survival, p...

journal_title：Technology in cancer research & treatment

authors： Comito T,Cozzi L,Clerici E,Franzese C,Tozzi A,Iftode C,Navarria P,D'Agostino G,Rimassa L,Carnaghi C,Personeni N,Tronconi MC,De Rose F,Franceschini D,Ascolese AM,Fogliata A,Tomatis S,Santoro A,Zerbi A,Scorsetti M

更新日期：2017-06-01 00:00:00

abstract：:Irreversible electroporation (IRE) has been shown to be an effective method of killing cells locally. In contrast to radiofrequency ablation, the mechanism by which cells are thought to die via IRE is the creation of pores in cell membranes, without substantial increase in tissue temperature. To determine the degree t...

journal_title：Technology in cancer research & treatment

authors： Long G,Bakos G,Shires PK,Gritter L,Crissman JW,Harris JL,Clymer JW

更新日期：2014-12-01 00:00:00

abstract：:Electrochemotherapy is an effective antitumor treatment employing locally applied high voltage electric pulses delivered through conductive electrodes to the tumor in combination with chemotherapeutic drugs. The efficiency of electrochemotherapy strongly depends on the local electric field distribution inside the targ...

journal_title：Technology in cancer research & treatment

authors： Corovic S,Al Sakere B,Haddad V,Miklavcic D,Mir LM

更新日期：2008-10-01 00:00:00

abstract：:We describe the first histopathologic analysis of prostatic tissue following hypofractionated robotic radiation therapy. A 66 year-old man presented with stage II, low risk adenocarcinoma of the prostate and underwent elective conformal hypofractionated radiation therapy. His pretreatment evaluation revealed T1c adeno...

journal_title：Technology in cancer research & treatment

authors： Suy S,Oermann E,Hanscom H,Lei S,Vahdat S,Yu X,Park HU,Chen V,Collins BT,McGeagh K,Dawson N,Jha R,Azumi N,Dritschilo A,Lynch J,Collins SP

更新日期：2010-12-01 00:00:00

abstract：:The response of the tumor microvasculature to ionizing radiation can be modified to improve tumor control in preclinical mouse models of cancer. Recent studies have shown that a variety of cancer drugs can improve the response of cancers to radiotherapy. Protein tyrosine kinase inhibitors (TKIs) have been shown to enh...

journal_title：Technology in cancer research & treatment

authors： Lu B,Shinohara ET,Edwards E,Geng L,Tan J,Hallahan DE

更新日期：2005-12-01 00:00:00

abstract：:This study quantifies the setup uncertainties to optimize the planning target volume (PTV) margin based on daily image guidance, its dosimetric impact, and radiobiological implication for intensity-modulated radiation therapy (IMRT) in head and neck cancer. Ten patients were retrospectively chosen who had been treated...

journal_title：Technology in cancer research & treatment

authors： Srivastava SP,Cheng CW,Das IJ

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:To develop and evaluate an automatic intensity-modulated radiation therapy (IMRT) program for cervical cancer, including a Convolution Neural Network (CNN)-based prediction model and an automated optimization strategy. METHODS:A CNN deep learning model was trained to predict a patient-specify set of IMRT objec...

journal_title：Technology in cancer research & treatment

authors： Jihong C,Penggang B,Xiuchun Z,Kaiqiang C,Wenjuan C,Yitao D,Jiewei Q,Kerun Q,Jing Z,Tianming W

更新日期：2020-01-01 00:00:00

abstract：:As one of the common cancers that threaten human life, the recurrence and metastasis of colorectal cancer seriously affect the prognosis of patients. Although new drugs and comprehensive treatments have been adopted, the current treatment effect on this tumor, especially in advanced colorectal cancer, is still not sat...

journal_title：Technology in cancer research & treatment

authors： Ma YS,Li W,Liu Y,Shi Y,Lin QL,Fu D

更新日期：2020-01-01 00:00:00

abstract：:Our study was designed to investigate the role of B4GalT1 in glioblastoma, in vitro and in vivo, to detect whether B4GalT1 knockdown could regulate the development of glioblastoma, and further observe the relationship between B4GalT1 knockdown and the apoptosis and autophagy of glioblastoma. To begin, we looked at TCG...

journal_title：Technology in cancer research & treatment

authors： Wang P,Li X,Xie Y

更新日期：2020-01-01 00:00:00