Knockdown of protein phosphatase magnesium-dependent 1 (PPM1D) through lentivirus-mediated RNA silencing inhibits colorectal carcinoma cell proliferation.

abstract：:Hepatocellular carcinoma (HCC) is the most aggressive type of gastrointestinal tumor, with a high rate of mortality. However, identifying biomarkers for the treatment of HCC remains to be developed. We aimed to determine whether cell division cycle 25C (CDC25C) could be used as a novel diagnostic and therapeutic bioma...

journal_title：Technology in cancer research & treatment

authors： Xun R,Lu H,Wang X

更新日期：2020-01-01 00:00:00

abstract：:Electrochemotherapy is an effective antitumor treatment employing locally applied high voltage electric pulses delivered through conductive electrodes to the tumor in combination with chemotherapeutic drugs. The efficiency of electrochemotherapy strongly depends on the local electric field distribution inside the targ...

journal_title：Technology in cancer research & treatment

authors： Corovic S,Al Sakere B,Haddad V,Miklavcic D,Mir LM

更新日期：2008-10-01 00:00:00

abstract：:This study aimed to analysis outcome and prognosis of interstitial 125I seed implantation in patients with cervical lymph node recurrence after multimodal treatment of thoracic esophageal squamous cell carcinoma (ESCC). We conducted a retrospective review of 19 patients with 32 cervical lymph nodes recurrences after m...

journal_title：Technology in cancer research & treatment

authors： Lin L,Wang J,Jiang Y,Meng N,Tian S,Yang R,Ran W,Liu C

更新日期：2015-04-01 00:00:00

abstract：:Stereotactic body radiation therapy is a well-tolerated modality for the treatment of primary and metastatic liver lesions, and fiducials are often used as surrogates for tumor tracking during treatment. We evaluated respiratory-induced liver deformation by measuring the rigidity of the fiducial configuration during t...

journal_title：Technology in cancer research & treatment

authors： Paulsson AK,Yom SS,Anwar M,Pinnaduwage D,Sudhyadhom A,Gottschalk AR,Chang AJ,Descovich M

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the efficacy and toxicity of robotic CyberKnife (Accuray Incorporated, Sunnyvale, California)-based stereotactic body radiation therapy (SBRT) in patients with recurrent or metastatic abdominopelvic tumors. METHODS AND MATERIALS:A total of 69 patients treated between Ma...

journal_title：Technology in cancer research & treatment

authors： Sezen D,Gurkaynak M,Gultekin M,Cengiz M,Yildiz F,Zorlu F,Akyol F,Yazici G,Hurmuz P,Ozyigit G

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:To assess the efficacy of stereotactic body radiotherapy in patients with unresectable locally advanced pancreatic cancer. MATERIALS AND METHODS:All patients received a prescription dose of 45 Gy in 6 fractions. Primary end point was freedom from local progression. Secondary end points were overall survival, p...

journal_title：Technology in cancer research & treatment

authors： Comito T,Cozzi L,Clerici E,Franzese C,Tozzi A,Iftode C,Navarria P,D'Agostino G,Rimassa L,Carnaghi C,Personeni N,Tronconi MC,De Rose F,Franceschini D,Ascolese AM,Fogliata A,Tomatis S,Santoro A,Zerbi A,Scorsetti M

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Circulating tumor cells (CTCs) hold huge potential for both clinical applications and basic research into the management of cancer, but the relationship between CTC count and cervical cancer prognosis remains unclear. Therefore, research on this topic is urgently required. OBJECTIVE:This study investigated ...

journal_title：Technology in cancer research & treatment

authors： Du K,Huang Q,Bu J,Zhou J,Huang Z,Li J

更新日期：2020-01-01 00:00:00

abstract：:MicroRNAs are reported as a vital important factor in cancer cell initiation and progression processes. MicroRNA-19-3p has drawn the attention of many researchers in recent years because of its wide expression and its key role in serious kinds of tumor cells. However, the detailed mechanism of microRNA-19a-3p in these...

journal_title：Technology in cancer research & treatment

authors： Su YF,Zang YF,Wang YH,Ding YL

更新日期：2020-01-01 00:00:00

abstract：:The aim of this study is to evaluate the volume differences between contrast-enhanced CT-based left ventricle (LV) and PET-CT-based LV and assess the impact of dose on the substructure volume differences in patients with left breast cancer treated with adjuvant radiotherapy. From October 2008 to February 2009, 14 pati...

journal_title：Technology in cancer research & treatment

authors： Yu XL,Zhang Q,Chen JY,Zhang Z,Wang JZ,Hu WG,Pan ZQ,Hu SL,Zhang YJ,Feng Y,Shao ZM,Orecchia R,Guo XM

更新日期：2013-04-01 00:00:00

abstract：:Tumor-infiltrating immune cells are part of a complex microenvironment and associated with improved clinical outcomes in a broad range of tumor types. However, a detailed map for the prognostic landscape of tumor-infiltrating immune cells and immune checkpoint modulators in glioblastoma is still lacking. Here, with th...

journal_title：Technology in cancer research & treatment

authors： Wu S,Yang W,Zhang H,Ren Y,Fang Z,Yuan C,Yao Z

更新日期：2019-01-01 00:00:00

abstract：:In cryosurgery it is crucial that the performance of cryoprobes is predictable and constant. In this study we tested the intra- and interneedle variation between 17-gauge cryoprobes in two homogeneous mediums. Also, a multiprobe setup was tested. Cryoprobe performance was defined as the time it takes one cryoprobe to ...

journal_title：Technology in cancer research & treatment

authors： Beemster PW,Lagerveld BW,Witte LP,de la Rosette JJ,Pes MP,Wijkstra H

更新日期：2008-08-01 00:00:00

abstract：:The therapy of brain tumors has been limited by a lack of effective methods of drug delivery to the brain. Systemic administration is often associated with toxic side effects and ultimately fails to achieve therapeutic concentrations within a tumor. An attractive strategy that has gained importance in brain tumor ther...

journal_title：Technology in cancer research & treatment

authors： Lesniak MS

更新日期：2005-08-01 00:00:00

abstract：:eLiposomes encapsulate a perfluorocarbon nanoemulsion droplet inside a liposome. Ultrasound is then used as a trigger mechanism to vaporize the perfluorocarbon, break the liposome, and release the desired drug to the tumor tissue. The purpose of this research is to show that eLiposomes synthesized using perfluoropenta...

journal_title：Technology in cancer research & treatment

authors： Husseini GA,Pitt WG,Javadi M

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To develop and evaluate an automatic intensity-modulated radiation therapy (IMRT) program for cervical cancer, including a Convolution Neural Network (CNN)-based prediction model and an automated optimization strategy. METHODS:A CNN deep learning model was trained to predict a patient-specify set of IMRT objec...

journal_title：Technology in cancer research & treatment

authors： Jihong C,Penggang B,Xiuchun Z,Kaiqiang C,Wenjuan C,Yitao D,Jiewei Q,Kerun Q,Jing Z,Tianming W

更新日期：2020-01-01 00:00:00

abstract：:Poorly differentiated cell populations including tumor-initiating stem cells have been demonstrated to display a unique ability to natively internalize fragmented double-stranded DNA. Using this feature as a marker, we show that 0.1% to 6% of human glioblastoma cells from the bioptates can effectively internalize a fl...

journal_title：Technology in cancer research & treatment

authors： Dolgova EV,Mishinov SV,Proskurina AS,Potter EA,Efremov YR,Bayborodin SI,Tyrinova TV,Stupak VV,Ostatin AA,Chernykh ER,Bogachev SS

更新日期：2018-01-01 00:00:00

abstract：:Although an MRI scanner is a single stand-alone modality, different acquisition techniques may be applied to collect structural and functional information, including vascular or angiogenic properties measured by dynamic contrast enhanced MRI (DCE-MRI) and Choline (Cho) metabolism measured by proton MR spectroscopy ima...

journal_title：Technology in cancer research & treatment

authors： Su MY,Baik HM,Yu HJ,Chen JH,Mehta RS,Nalcioglu O

更新日期：2006-08-01 00:00:00

abstract：:One of the most lethal carcinomas is pancreatic cancer. As standard treatment using chemotherapy and radiation has shown limited success, thermal regimens (cryotherapy or heat ablation) are emerging as viable alternatives. Although promising, our understanding of pancreatic cancer response to thermal ablation remains ...

journal_title：Technology in cancer research & treatment

authors： Baumann KW,Baust JM,Snyder KK,Baust JG,Van Buskirk RG

更新日期：2017-08-01 00:00:00

abstract：:Ionizing radiation therapy is one of the primary modalities for treating cancers. Ideally, the particle selected to deliver ionizing radiation for routine therapy should control the disease, cause minimal side effects, and be affordable. Two major properties for judging the utility of a particle, physical controllabil...

journal_title：Technology in cancer research & treatment

authors： Slater JM

更新日期：2007-08-01 00:00:00

abstract：:Tumstatin (Tum) is a powerful angiostatin that inhibits proliferation and induces apoptosis of tumorous vascular endothelial cells. A nonpathogenic and anaerobic bacterium, Bifidobacterium longum (BL), selectively localizes to and proliferates in the hypoxia location within solid tumor. The aims of this study were to ...

journal_title：Technology in cancer research & treatment

authors： Wei C,Xun AY,Wei XX,Yao J,Wang JY,Shi RY,Yang GH,Li YX,Xu ZL,Lai MG,Zhang R,Wang LS,Zeng WS

更新日期：2016-06-01 00:00:00

abstract：:To quantify the advantages of a 6 degrees of freedom (dof) versus the conventional 3- or 4-dof correction modality for stereotactic body radiation therapy (SBRT) treatments. Eighty-five patients were fitted with 5-7 infra-red passive markers for optical localization. Data, acquired during the treatment, were analyzed ...

journal_title：Technology in cancer research & treatment

authors： Spadea MF,Baroni G,Riboldi M,Luraschi R,Tagaste B,Garibaldi C,Catalano G,Orecchia R,Pedotti A

更新日期：2008-06-01 00:00:00

abstract：INTRODUCTION:Osteosarcoma is the most common primary tumor of bone, although some molecular markers have been identified, the detailed molecular mechanisms underlying osteosarcoma are currently not fully understood. In the present study, we attempted to identify the potential key genes and pathways in osteosarcoma usin...

journal_title：Technology in cancer research & treatment

authors： Li Q,Liang J,Chen B

更新日期：2020-01-01 00:00:00

abstract：:The treatment of patients with malignant brain tumors, in particular glioblastoma multiforme (GBM) is very challenging because of their diffuse infiltrative nature and the cytological heterogeneity. The median survival of patients with newly diagnosed GBM is only 12-15 months, and only 8-12% of them survive for two ye...

journal_title：Technology in cancer research & treatment

authors： Kioi M,Husain SR,Croteau D,Kunwar S,Puri RK

更新日期：2006-06-01 00:00:00

abstract：:Stereotactic radiosurgery (SRS) refers to a single radiation treatment delivering a high dose to an intra-cranial target localized in three-dimensions by CT and/or MRI imaging. Traditionally, immobilization of the patient's head has been achieved using a rigid stereotactic head frame as the key step in allowing for ac...

journal_title：Technology in cancer research & treatment

authors： Sahgal A,Ma L,Chang E,Shiu A,Larson DA,Laperriere N,Yin FF,Tsao M,Menard C,Basran P,Létourneau D,Heydarian M,Beachey D,Shukla V,Cusimano M,Hodaie M,Zadeh G,Bernstein M,Schwartz M

更新日期：2009-08-01 00:00:00

abstract：:A review of the literature on the current applications of breast magnetic resonance imaging (MRI) indications, their rationale and their place in diagnosis and management of breast cancer was given. Contrast-enhanced breast MRI is developing as a valuable adjunct to mammography and sonography. Its high sensitivity for...

journal_title：Technology in cancer research & treatment

authors： Pavic D,Koomen MA,Kuzmiak CM,Lee YH,Pisano ED

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Long noncoding RNAs (lncRNAs) are potential biomarkers for cancers. Nevertheless, the ability of long noncoding RNA lung cancer-associated transcript 1 in patients with multiple myeloma remains unknown. The purpose of this current study was to figure out its function in multiple myeloma. METHODS:Firstly, the...

journal_title：Technology in cancer research & treatment

authors： Liu Z,Gao H,Peng Q,Yang Y

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Neoadjuvant chemoradiotherapy (nCRT) followed by operation has become the standard treatment for locally advanced rectal cancer (LARC). However, considering the possible toxicity and complications of radiochemotherapy, nCRT is seldom used for the elderly. The purpose of this study was to assess the safety ...

journal_title：Technology in cancer research & treatment

authors： Liu H,Li C,Zhao Z,Guan X,Yang M,Liu Z,Tang Y,Jiang Z,Wang X

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Rectal cancer ranks as the eighth in cancer-related morbidity and the tenth in the cancer-related mortality. A few studies have explored several biomarkers for colorectal cancer. However, there is still a great need for us to excavate novel biomarkers with effective and efficient diagnostic and prognostic ...

journal_title：Technology in cancer research & treatment

authors： Xu Z,Li Y,Cui Y,Guo Y

更新日期：2020-01-01 00:00:00

abstract：:Recombinant Newcastle Disease Virus (rNDV) has shown oncolytic therapeutic effect in preclinical studies. Previous data indicate that rNDV carrying IL2 has shown promise in cancer therapy. Due to the significant side effects of IL2, IL15 has been introduced into cancer therapy. A number of studies have suggested that ...

journal_title：Technology in cancer research & treatment

authors： Niu Z,Bai F,Sun T,Tian H,Yu D,Yin J,Li S,Li T,Cao H,Yu Q,Wu Y,Ren G,Li D

更新日期：2015-10-01 00:00:00

abstract：:The integrated use of optical technologies for patient monitoring is addressed in the framework of time-resolved treatment delivery for scanned ion beam therapy. A software application has been designed to provide the therapy control system (TCS) with a continuous geometrical feedback by processing the external surrog...

journal_title：Technology in cancer research & treatment

authors： Fattori G,Saito N,Seregni M,Kaderka R,Pella A,Constantinescu A,Riboldi M,Steidl P,Cerveri P,Bert C,Durante M,Baroni G

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To investigate the role of intensity-modulated proton therapy (IMPT) for hepatocellular carcinoma (HCC) patients to be treated with stereotactic body radiation therapy (SBRT) in a risk-adapted dose prescription regimen. METHODS:A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escala...

journal_title：Technology in cancer research & treatment

authors： Cozzi L,Comito T,Loi M,Fogliata A,Franzese C,Franceschini D,Clerici E,Reggiori G,Tomatis S,Scorsetti M

更新日期：2020-01-01 00:00:00