MicroRNA-214 targets PTK6 to inhibit tumorigenic potential and increase drug sensitivity of prostate cancer cells.

abstract：:This study investigated the effects of 4 aeration levels (varied by injection of air to the soil through subsurface irrigation lines) at two subsurface irrigation line depths (15 and 40 cm) on plant growth, yield and nutritional quality of greenhouse tomato. In all experiments, fruit number, width and length, yield, v...

journal_title：Scientific reports

authors： Li Y,Niu W,Dyck M,Wang J,Zou X

更新日期：2016-12-20 00:00:00

abstract：:Pulsatillae radix is a conventional traditional Chinese medicine (TCM) with common name Baitouweng, and has notable effects on inflammation and dysentery. Pulsatilla chinensis (Bge.) Regel is the only source plant of Baitouweng recorded in Chinese Pharmacopoeia, but its adulteration often occurs in the market that pos...

journal_title：Scientific reports

authors： Shi Y,Zhao M,Yao H,Yang P,Xin T,Li B,Sun W,Chen S

更新日期：2017-01-06 00:00:00

abstract：:Cassava is an important staple crop in tropical and sub-tropical areas. As a common farming practice, cassava is usually cultivated intercropping with other crops and subjected to various degrees of shading, which causes reduced productivity. Herein, a comparative transcriptomic analysis was performed on a series of d...

journal_title：Scientific reports

authors： Ding Z,Zhang Y,Xiao Y,Liu F,Wang M,Zhu X,Liu P,Sun Q,Wang W,Peng M,Brutnell T,Li P

更新日期：2016-08-19 00:00:00

abstract：:Non-Markovianity has recently attracted large interest due to significant advances in its characterization and its exploitation for quantum information processing. However, up to now, only non-Markovian regimes featuring environment to system backflow of information (strong non-Markovianity) have been experimentally s...

journal_title：Scientific reports

authors： Bernardes NK,Cuevas A,Orieux A,Monken CH,Mataloni P,Sciarrino F,Santos MF

更新日期：2015-12-02 00:00:00

abstract：:Cuprizone-induced demyelination in mice is a frequently used model in preclinical multiple sclerosis research. A recent quantitative clinically-targeted MRI method, fast macromolecular proton fraction (MPF) mapping demonstrated a promise as a myelin biomarker in human and animal studies with a particular advantage of ...

journal_title：Scientific reports

authors： Khodanovich MY,Sorokina IV,Glazacheva VY,Akulov AE,Nemirovich-Danchenko NM,Romashchenko AV,Tolstikova TG,Mustafina LR,Yarnykh VL

更新日期：2017-04-24 00:00:00

abstract：:We investigated molecular dissociation induced by 10-keV X-ray irradiation in dense ice at pressures up to 40 GPa at 300 K. The dissociation yield estimated from the oxygen K-edge X-ray Raman spectra, showed that the molecular dissociation was enhanced up to 14 GPa and gradually suppressed on further compression to 40...

journal_title：Scientific reports

authors： Fukui H,Hiraoka N,Hirao N,Aoki K,Akahama Y

更新日期：2016-05-25 00:00:00

abstract：:Isoliquiritigenin (ISL), a natural flavonoid extracted from licorice, has been demonstrated to exert attenuation of osteoclastogenesis and anti-angiogenesis activity in a wide variety of cells. Here, we first evaluated the effects of ISL on pathogenesis of osteoarthritis in a mouse model of OA. The data showed that IS...

journal_title：Scientific reports

authors： Ji B,Zhang Z,Guo W,Ma H,Xu B,Mu W,Amat A,Cao L

更新日期：2018-01-29 00:00:00

abstract：:Innate immunity has been extended to respond environmental pathogen other than microbial components. Here we explore a novel pollen/TLR4 innate immunity in allergic inflammation. In experimental allergic conjunctivitis induced by short ragweed (SRW) pollen, typical allergic signs, stimulated IL-33/ST2 signaling and ov...

journal_title：Scientific reports

authors： Li J,Zhang L,Chen X,Chen D,Hua X,Bian F,Deng R,Lu F,Li Z,Pflugfelder SC,Li DQ

更新日期：2016-10-31 00:00:00

abstract：:The Na(3p) + H2(X1Σg+) → NaH(X1Σ+) + H(2S) reaction plays an important role in the field of diabatic reaction dynamics. A set of new diabatic potential energy surfaces (PESs) of the NaH2 system are structured, which include the diabatic coupling between the lowest two adiabatic states. The electronic structure calcula...

journal_title：Scientific reports

authors： Wang S,Yang Z,Yuan J,Chen M

更新日期：2018-12-19 00:00:00

abstract：:One of the most challenging issues in HIV-associated neurocognitive disorders (HAND) caused by HIV-1 virotoxins and drug abuse is the lack of understanding the underlying mechanisms that are commonly associated with disorders of the blood-brain barrier (BBB), which mainly consists of brain microvascular endothelial ce...

journal_title：Scientific reports

authors： Liu L,Yu J,Li L,Zhang B,Liu L,Wu CH,Jong A,Mao DA,Huang SH

更新日期：2017-01-11 00:00:00

abstract：:Drosophila melanogaster is a promiscuous species that inhabits a large range of harsh environments including flooded habitats and varying temperature changes. To survive these environments, fruit flies have adapted mechanisms of tolerance that allow them to thrive. During exposure to anoxic stress, fruit flies and oth...

journal_title：Scientific reports

authors： Benasayag-Meszaros R,Risley MG,Hernandez P,Fendrich M,Dawson-Scully K

更新日期：2015-03-17 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) can cause multidimensional cognitive deficits, among which working memory (WM) is usually involved at an early stage. However, the neural substrates underlying impaired WM in T2DM patients are still unclear. To clarify this issue, we utilized functional magnetic resonance imaging (fMRI)...

journal_title：Scientific reports

authors： Zhang Y,Lu S,Liu C,Zhang H,Zhou X,Ni C,Qin W,Zhang Q

更新日期：2016-03-29 00:00:00

abstract：:Mammalian parental genomes contribute differently to early embryonic development. Before activation of the zygotic genome, the maternal genome provides all transcripts and proteins required for the transition from a highly specialized oocyte to a pluripotent embryo. Depletion of these maternally-encoded transcripts fr...

journal_title：Scientific reports

authors： Mahadevan S,Sathappan V,Utama B,Lorenzo I,Kaskar K,Van den Veyver IB

更新日期：2017-03-20 00:00:00

abstract：:Despite dedicated research has been carried out to adequately map the distribution of the sperm whale in the Mediterranean Sea, unlike other regions of the world, the species population status is still presently uncertain. The analysis of two years of continuous acoustic data provided by the ANTARES neutrino telescope...

journal_title：Scientific reports

authors： André M,Caballé A,van der Schaar M,Solsona A,Houégnigan L,Zaugg S,Sánchez AM,Castell JV,Solé M,Vila F,Djokic D,Adrián-Martínez S,Albert A,Anghinolfi M,Anton G,Ardid M,Aubert JJ,Avgitas T,Baret B,Barrios-Martí J,Ba

更新日期：2017-04-12 00:00:00

abstract：:The relationship between obstructive sleep apnea (OSA) and chronic rhinosinusitis (CRS) still remains unclear. This retrospective cohort study aimed to investigate the relationship between OSA and subsequent CRS using a population-based dataset. The study used data from the Taiwan Longitudinal Health Insurance Databas...

journal_title：Scientific reports

authors： Kao LT,Hung SH,Lin HC,Liu CK,Huang HM,Wu CS

更新日期：2016-02-10 00:00:00

abstract：:Lack of effective anti-metastatic drugs creates a major hurdle for metastatic lung cancer therapy. For successful lung cancer treatment, there is a strong need of newer therapeutics with metastasis-inhibitory potential. In the present study, we determined the anti-metastatic and anti-angiogenic potential of a natural ...

journal_title：Scientific reports

authors： Shukla S,Sinha S,Khan S,Kumar S,Singh K,Mitra K,Maurya R,Meeran SM

更新日期：2016-02-24 00:00:00

abstract：:Atrial fibrillation (AF) is known to cause adverse remodeling of left atrium (LA). Radiofrequency catheter ablation (RFCA) of AF is associated with decrease in LA volume. However, the impact of RFCA on left atrial appendage (LAA) volume and hemodynamic function is not fully understood. We analyzed 123 patients who und...

journal_title：Scientific reports

authors： Kim YG,Shim J,Oh SK,Park HS,Lee KN,Hwang SH,Choi JI,Kim YH

更新日期：2018-05-18 00:00:00

abstract：:MicroRNAs can promote translation of specific mRNAs in quiescent (G0) mammalian cells and immature Xenopus laevis oocytes. We report that microRNA-mediated upregulation of target mRNAs in oocytes is dependent on nuclear entry of the microRNA; cytoplasmically-injected microRNA repress target mRNAs. Components of the ac...

journal_title：Scientific reports

authors： Truesdell SS,Mortensen RD,Seo M,Schroeder JC,Lee JH,LeTonqueze O,Vasudevan S

更新日期：2012-01-01 00:00:00

abstract：:In this work, we demonstrate an innovative approach, combing a novel active screen plasma (ASP) technique with green chemical synthesis, for a direct fabrication of uniform Pt nanowire arrays on large-area supports. The ASP treatment enables in-situ N-doping and surface modification to the support surface, significant...

journal_title：Scientific reports

authors： Du S,Lin K,Malladi SK,Lu Y,Sun S,Xu Q,Steinberger-Wilckens R,Dong H

更新日期：2014-09-22 00:00:00

abstract：:Alternative tillage and rice establishment options should aim at less water and labor to produce similar or improved yields compared with traditional puddled-transplanted rice cultivation. The relative performance of these practices in terms of yield, water input, and economics varies across rice-growing regions. A gl...

journal_title：Scientific reports

authors： Chakraborty D,Ladha JK,Rana DS,Jat ML,Gathala MK,Yadav S,Rao AN,Ramesha MS,Raman A

更新日期：2017-08-24 00:00:00

abstract：:Mitochondria-generated reactive oxygen species (mROS) are frequently associated with DNA damage and cell cycle arrest, but physiological increases in mROS serve to regulate specific cell functions. T3 is a major regulator of mROS, including hydrogen peroxide (H2O2). Here we show that exogenous thyroid hormone (T3) adm...

journal_title：Scientific reports

authors： Tan L,Bogush N,Naib H,Perry J,Calvert JW,Martin DIK,Graham RM,Naqvi N,Husain A

更新日期：2019-11-27 00:00:00

abstract：:Keratin 15 (K15), a type I keratin, which pairs with K5 in epidermis, has been used extensively as a biomarker for stem cells. Two commercial antibodies, LHK15, a mouse monoclonal and EPR1614Y, a rabbit monoclonal, have been widely employed to study K15 expression. Here we report differential reactivity of these antib...

journal_title：Scientific reports

authors： Aldehlawi H,Niemiec KA,Avisetti DR,Lalli A,Teh MT,Waseem A

更新日期：2019-02-13 00:00:00

abstract：:Medulloblastoma (MB), the most common malignant paediatric brain tumour occurs in the cerebellum. Advances in molecular genomics have led to the identification of defined subgroups which are associated with distinct clinical prognoses. Despite this classification, standard therapies for all subgroups often leave child...

journal_title：Scientific reports

authors： Mather RL,Loveson KF,Fillmore HL

更新日期：2019-06-13 00:00:00

abstract：:Modulating the tumor microenvironment to promote an effective immune response is critical in managing any type of tumor. Melanoma is an aggressive skin cancer and the incidence rate is increasing worldwide. Potent protease inhibitors have recently been extensively researched as potential therapeutic agents against var...

journal_title：Scientific reports

authors： Ranasinghe SL,Rivera V,Boyle GM,McManus DP

更新日期：2019-11-07 00:00:00

abstract：:Short term treatment with low doses of glucocorticoid analogues has been shown to ameliorate neurological symptoms in Ataxia-Telangiectasia (A-T), a rare autosomal recessive multisystem disease that mainly affects the cerebellum, immune system, and lungs. Molecular mechanisms underlying this clinical observation are u...

journal_title：Scientific reports

authors： Pozzi E,Giorgio E,Mancini C,Lo Buono N,Augeri S,Ferrero M,Di Gregorio E,Riberi E,Vinciguerra M,Nanetti L,Bianchi FT,Sassi MP,Costanzo V,Mariotti C,Funaro A,Cavalieri S,Brusco A

更新日期：2020-11-19 00:00:00

abstract：:Circuit QED on a chip has become a powerful platform for simulating complex many-body physics. In this report, we realize a Dicke-Ising model with an antiferromagnetic nearest-neighbor spin-spin interaction in circuit QED with a superconducting qubit array. We show that this system exhibits a competition between the c...

journal_title：Scientific reports

authors： Zhang Y,Yu L,Liang JQ,Chen G,Jia S,Nori F

更新日期：2014-02-13 00:00:00

abstract：:Detection of visible blind UV radiation is not only interesting but also of technologically important. Herein, we demonstrate the efficient detection of UV radiation by using cluster like ZnS quantum dot solid nanostructures prepared by simple reflux condensation technique. The short-chain ligand 3-mercaptopropionic a...

journal_title：Scientific reports

authors： Premkumar S,Nataraj D,Bharathi G,Ramya S,Thangadurai TD

更新日期：2019-12-10 00:00:00

abstract：:The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by neurons in the lateral hypothalamus and zona incerta. MCHergic neurons project throughout the central nervous system, indicating the involvements of many physiological functions, but the role in pain has yet to be determined. In thi...

journal_title：Scientific reports

authors： Jang JH,Park JY,Oh JY,Bae SJ,Jang H,Jeon S,Kim J,Park HJ

更新日期：2018-01-15 00:00:00

abstract：:Combining endurance training with resistance training (RT) may attenuate skeletal muscle hypertrophic adaptation versus RT alone; however, the underlying mechanisms are unclear. We investigated changes in markers of ribosome biogenesis, a process linked with skeletal muscle hypertrophy, following concurrent training v...

journal_title：Scientific reports

authors： Fyfe JJ,Bishop DJ,Bartlett JD,Hanson ED,Anderson MJ,Garnham AP,Stepto NK

更新日期：2018-01-12 00:00:00

abstract：:Fluorescent probes that can distinguish different DNA topologies through changes in optical readout are sought after for DNA-based diagnostics. In this work, the 4,4-difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) chromophore attached to cyanophenyl substituents (BODIPY-CN) has been tethered to the 5'-end of the 15-m...

journal_title：Scientific reports

authors： Deore PS,Soldatov DV,Manderville RA

更新日期：2018-11-15 00:00:00