Rapidly discriminate commercial medicinal Pulsatilla chinensis (Bge.) Regel from its adulterants using ITS2 barcoding and specific PCR-RFLP assay.

abstract：:The genetics underlying autism spectrum disorder (ASD) are complex. Approximately 3-5% of ASD cases arise from maternally inherited duplications of 15q11.2-q13.1, termed Duplication 15q syndrome (Dup15q). 15q11.2-q13.1 includes the gene UBE3A which is believed to underlie ASD observed in Dup15q syndrome. UBE3A is an E...

journal_title：Scientific reports

authors： Hope KA,McGinn A,Reiter LT

更新日期：2019-02-20 00:00:00

abstract：:Detrimental impacts of extreme heats on the U.S. crop yields have been well-documented by a number of empirical studies. However, less have focused on within-growing season weather variation and the interaction between temperature and precipitation. The objective of this study is to emphasize the importance of disaggr...

journal_title：Scientific reports

authors： Yu J,Goh G

更新日期：2019-12-06 00:00:00

abstract：:There is a lack of evidence that either conventional observational rating scale or biomechanical system is a better tremor assessment tool. This work focuses on comparing a biomechanical system and the Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale in terms of test-retest ...

journal_title：Scientific reports

authors： Chan PY,Mohd Ripin Z,Abdul Halim S,Kamarudin MI,Ng KS,Eow GB,Tan K,Cheah CF,Then L,Soong N,Hor JY,Yahya AS,Arifin WN,Tharakan J,Mustapha M

更新日期：2019-05-31 00:00:00

abstract：:Colloidal based films have been widely developed for a wide range of applications including chemical and electrical barrier coatings, photonic materials, biomaterials, and pharmaceutical oral drug delivery. Many previous studies investigate methods to generate uniformity or desired stratification of the final componen...

journal_title：Scientific reports

authors： Kaewpetch T,Gilchrist JF

更新日期：2020-06-24 00:00:00

abstract：:Third-generation sequencing technologies allow to sequence long reads of tens of kbp, that are expected to solve various problems. However, they display high error rates, currently capped around 10%. Self-correction is thus regularly used in long reads analysis projects. We introduce CONSENT, a new self-correction met...

journal_title：Scientific reports

authors： Morisse P,Marchet C,Limasset A,Lecroq T,Lefebvre A

更新日期：2021-01-12 00:00:00

abstract：:The critical importance of human milk to infants and even human civilization has been well established. Yet our understanding of the milk microbiome has been limited to cataloguing OTUs and computation of community diversity. To the best of our knowledge, there has been no report on the bacterial interactions within t...

journal_title：Scientific reports

authors： Sam Ma Z,Guan Q,Ye C,Zhang C,Foster JA,Forney LJ

更新日期：2015-02-05 00:00:00

abstract：:In contrast to mild infections of Group A Streptococcus (GAS) invasive infections of GAS still pose a serious health hazard: GAS disseminates from sterile sites into the blood stream or deep tissues and causes sepsis or necrotizing fasciitis. In this case antibiotics do not provide an effective cure as the bacteria ar...

journal_title：Scientific reports

authors： Rox K,Jansen R,Loof TG,Gillen CM,Bernecker S,Walker MJ,Chhatwal GS,Müller R

更新日期：2017-09-18 00:00:00

abstract：:The incidence of myopia is increasing worldwide, and the investigation on pathophysiology of myopia is becoming more important. This retrospective study aimed to compare the thicknesses of individual retinal layers between high-myopic and control eyes, and to evaluate the effects of age and sex on each retinal layer t...

journal_title：Scientific reports

authors： Kim JH,Lee SH,Han JY,Kang HG,Byeon SH,Kim SS,Koh HJ,Lee SC,Kim M

更新日期：2019-09-30 00:00:00

abstract：:The bulk-insulating topological insulators with tunable surface states are necessary for applications in spintronics and quantum computation. Here we present theoretical evidence for modulating the topological surface states and achieving the insulating bulk states in solid-solution (Bi(1-x)Sb(x))(2)Te(3). Our results...

journal_title：Scientific reports

authors： Niu C,Dai Y,Zhu Y,Ma Y,Yu L,Han S,Huang B

更新日期：2012-01-01 00:00:00

abstract：:Although the search for quantitative trait loci for behaviour remains a considerable challenge, the complicated genetic architecture of quantitative traits is beginning to be understood. The current project utilised heterogeneous stock (HS) male mice (n = 580) to investigate the genetic basis for brain weights, activi...

journal_title：Scientific reports

authors： Janecka M,Marzi SJ,Parsons MJ,Liu L,Paya-Cano JL,Smith RG,Fernandes C,Schalkwyk LC

更新日期：2017-02-01 00:00:00

abstract：:Despite increasing work detailing the presence of foraging specializations across a range of taxa, limited attention so far has been given to the role of spatiotemporal variation in food predictability in shaping individual resource selection. Here, we studied the exploitation of human-provided carrion resources diffe...

journal_title：Scientific reports

authors： van Overveld T,García-Alfonso M,Dingemanse NJ,Bouten W,Gangoso L,de la Riva M,Serrano D,Donázar JA

更新日期：2018-10-11 00:00:00

abstract：:In the cochlea, mammals maintain a uniquely high endolymphatic potential (EP), which is not observed in other vertebrate groups. However, a high [K+] is always present in the inner ear endolymph. Here, we show that Kir4.1, which is required in the mammalian stria vascularis to generate the highly positive EP, is absen...

journal_title：Scientific reports

authors： Wilms V,Köppl C,Söffgen C,Hartmann AM,Nothwang HG

更新日期：2016-09-29 00:00:00

abstract：:The aim of this prospective study was to evaluate the changes in stereopsis in patients who underwent vitrectomy for macular hole (MH) and assess the relationship between stereopsis and retinal microstructures. Fifty-two patients who underwent successful vitrectomy for unilateral MH and 20 control participants were re...

journal_title：Scientific reports

authors： Okamoto F,Moriya Y,Sugiura Y,Murakami T,Morikawa S,Hoshi S,Hiraoka T,Oshika T

更新日期：2020-11-11 00:00:00

abstract：:Outer membrane vesicles (OMVs) have proven to be highly immunogenic and induced an immune response against bacterial infection in human clinics and animal models. We sought to investigate whether engineered OMVs can be a feasible antigen-delivery platform for efficiently inducing specific antibody responses. In this s...

journal_title：Scientific reports

authors： Huang W,Wang S,Yao Y,Xia Y,Yang X,Li K,Sun P,Liu C,Sun W,Bai H,Chu X,Li Y,Ma Y

更新日期：2016-11-16 00:00:00

abstract：:Pharmacological activities of some natural products diminish and even disappear after purification. In this study, we explored the mechanisms underlying the decrease of acute oral toxicity of Coptidis Rhizoma extract after purification. The water solubility, in vitro absorption, and plasma exposure of berberine (the m...

journal_title：Scientific reports

authors： Ma BL,Yin C,Zhang BK,Dai Y,Jia YQ,Yang Y,Li Q,Shi R,Wang TM,Wu JS,Li YY,Lin G,Ma YM

更新日期：2016-01-29 00:00:00

abstract：:A wide-band and tunable Q-switched erbium-doped fiber (EDF) laser operating at 1560.5 nm with a tungsten ditelluride (WTe2) saturable absorber (SA) is demonstrated. The semi-metallic nature of WTe2 as well as its small band gap and excellent nonlinear optical properties make it an excellent SA material. The laser cavi...

journal_title：Scientific reports

authors： Ahmad H,Albaqawi HS,Yusoff N,Yi CW

更新日期：2020-06-17 00:00:00

abstract：:Respiratory syncytial virus (RSV) is a significant cause of lower respiratory tract infection in infants and elderly. To understand the evolution of neutralizing epitopes on the RSV glycoprotein (G) and fusion (F) proteins, we conducted a multi-year surveillance program (OUTSMART-RSV) in the US. Analysis of 1,146 RSV ...

journal_title：Scientific reports

authors： Bin Lu,Liu H,Tabor DE,Tovchigrechko A,Qi Y,Ruzin A,Esser MT,Jin H

更新日期：2019-03-07 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been implicated in human pathology, however, their role in colorectal carcinogenesis have not been fully elucidated. In the current study, whole-transcriptome analysis was performed in 3 pairs of colorectal cancer (CRC) and matched normal mucosa (NM) by RNA sequencing (RNA-seq). Fol...

journal_title：Scientific reports

authors： Yamada A,Yu P,Lin W,Okugawa Y,Boland CR,Goel A

更新日期：2018-01-12 00:00:00

abstract：:Several carbon dots doping with diferent elements (Ca, Ag, Au) were fabricated and their catalytic properties had been investigated in this paper. It was found that the Ag-doped carbon dots (CDAg) had played a role of mimic enzyme on the reaction of HAuCl4-H2O2 and generated nanogold particles with surface enhanced Ra...

journal_title：Scientific reports

authors： Wang H,Huang X,Wen G,Jiang Z

更新日期：2019-07-10 00:00:00

abstract：:We determined the prevalence of hyposalivation and xerostomia in older Mexicans (≥60 years), and its relationship with diverse factors. A cross-sectional study was realized in elderly subjects from Pachuca, Mexico. Chewing-stimulated saliva was collected under standardized conditions and salivary flow was measured; su...

journal_title：Scientific reports

authors： Islas-Granillo H,Borges-Yáñez A,Fernández-Barrera MÁ,Ávila-Burgos L,Patiño-Marín N,Márquez-Corona ML,Mendoza-Rodríguez M,Medina-Solís CE

更新日期：2017-01-17 00:00:00

abstract：:Previous studies showed that better adherence to the Mediterranean diet (MD) is associated with lower risk of chronic diseases, but limited data are available on bone health. We investigated the association of the MD with bone mineral density (BMD) in Chinese adults. We included 2371 participants aged 40-75 years in t...

journal_title：Scientific reports

authors： Chen GD,Dong XW,Zhu YY,Tian HY,He J,Chen YM

更新日期：2016-05-09 00:00:00

abstract：:Regulation of the chromatin state is crucial for biological processes such as the regulation of transcription, DNA replication, and DNA damage repair. Here we show that knockdown of the BRD8 bromodomain protein - a subunit of the p400/Tip60 complex - leads to p21 induction, and concomitant cell cycle arrest in G1/S. W...

journal_title：Scientific reports

authors： Lashgari A,Fauteux M,Maréchal A,Gaudreau L

更新日期：2018-09-20 00:00:00

abstract：:Since the SOX2 amplification was identified in lung squamous cell carcinoma (lung SCC), SOX2 transcriptional downstream targets have been actively investigated; however, such targets are often cell line specific. Here, in order to identify highly consensus SOX2 downstream genes in lung SCC cells, we used RNA-seq data ...

journal_title：Scientific reports

authors： Fukazawa T,Guo M,Ishida N,Yamatsuji T,Takaoka M,Yokota E,Haisa M,Miyake N,Ikeda T,Okui T,Takigawa N,Maeda Y,Naomoto Y

更新日期：2016-02-05 00:00:00

abstract：:Jellyfish locomotion and orientation have been studied in the past both in the laboratory, testing mostly small jellyfish, and in the field, where it was impossible to control the seawater currents. Utilizing an outdoor water flume, we tested the locomotion of jellyfish when swimming against and with currents of up to...

journal_title：Scientific reports

authors： Malul D,Lotan T,Makovsky Y,Holzman R,Shavit U

更新日期：2019-12-30 00:00:00

abstract：:Wave propagation is an important characteristic for pattern formation and pattern dynamics. To date, various waves in homogeneous media have been investigated extensively and have been understood to a great extent. However, the wave behaviors in heterogeneous media have been studied and understood much less. In this w...

journal_title：Scientific reports

authors： Cui X,Huang X,Hu G

更新日期：2016-05-04 00:00:00

abstract：:As an important method for building blocks synthesis, whole cell biocatalysis is hindered by some shortcomings such as unpredictability of reactions, utilization of opportunistic pathogen, and side reactions. Due to its biological and extensively studied genetic background, Pseudomonas putida KT2440 is viewed as a pro...

journal_title：Scientific reports

authors： Wang Y,Lv M,Zhang Y,Xiao X,Jiang T,Zhang W,Hu C,Gao C,Ma C,Xu P

更新日期：2014-11-06 00:00:00

abstract：:It remains unclear how infantile febrile seizures (FS) enhance adult seizure susceptibility. Here we showed that the transient increase of interleukin-1β (IL-1β) after prolonged FS promoted adult seizure susceptibility, which was blocked by interleukin-1 receptor antagonist (IL-1Ra) within a critical time window. Post...

journal_title：Scientific reports

authors： Feng B,Tang Y,Chen B,Xu C,Wang Y,Dai Y,Wu D,Zhu J,Wang S,Zhou Y,Shi L,Hu W,Zhang X,Chen Z

更新日期：2016-02-23 00:00:00

abstract：:Implantable 3D engineered vascular tissue constructs can be formed by co-culturing endothelial and fibroblast cells on macroporous scaffolds. Here we show that these constructs can be used for studying the dynamics of neovascular formation in-vitro by a combination of live confocal imaging and an array of image proces...

journal_title：Scientific reports

authors： Blinder YJ,Freiman A,Raindel N,Mooney DJ,Levenberg S

更新日期：2015-12-09 00:00:00

abstract：:The aim of this study is to develop an internal-external correlation model for internal motion estimation for lung cancer radiotherapy. Deformation vector fields that characterize the internal-external motion are obtained by respectively registering the internal organ meshes and external surface meshes from the 4DCT i...

journal_title：Scientific reports

authors： Chen H,Zhong Z,Yang Y,Chen J,Zhou L,Zhen X,Gu X

更新日期：2018-02-27 00:00:00

abstract：:Anisotropically conductive materials are important components in subminiature devices. However, at this stage, some defects have limited practical applications of them, especially low anisotropic degree and high cost. Here, we report novel tricolor flag-liked microribbons array prepared by electrospinning technique. T...

journal_title：Scientific reports

authors： Ma Q,Yu W,Dong X,Yang M,Wang J,Liu G

更新日期：2015-09-28 00:00:00