Abstract：
:The aim of this prospective study was to evaluate the changes in stereopsis in patients who underwent vitrectomy for macular hole (MH) and assess the relationship between stereopsis and retinal microstructures. Fifty-two patients who underwent successful vitrectomy for unilateral MH and 20 control participants were recruited. We examined stereopsis using the Titmus Stereo Test (TST) and TNO stereotest (TNO), optical coherence tomography, and best-corrected visual acuity measurements, preoperatively, and at 3, 6, and 12 months postoperatively. As a result, preoperative and postoperative 3, 6, and 12-month values of stereopsis assessed by TST (log) were 2.7, 2.2, 2.2, and 2.2, respectively. TNO (log) were 2.8, 2.5, 2.4, and 2.4, respectively. Stereopsis in MH after surgery was significantly worse than that in normal participants (p < 0.001). Preoperative TST significantly correlated with MH size and defect length of external limiting membrane (ELM). Postoperative TST demonstrated significant correlation with the preoperative ELM defect length, and postoperative TNO was associated with the preoperative interdigitation zone defect length. Vitrectomy for MH significantly improved stereopsis, although not to normal levels. The ELM defect lengths, which approximately correspond to TST circles, are prognostic factors for postoperative stereopsis by TST. The interdigitation zone defect length, similar in size to the TNO index, is a prognostic factor for postoperative stereopsis by TNO.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Okamoto F,Moriya Y,Sugiura Y,Murakami T,Morikawa S,Hoshi S,Hiraoka T,Oshika Tdoi
10.1038/s41598-020-76648-4subject
Has Abstractpub_date
2020-11-11 00:00:00pages
19534issue
1issn
2045-2322pii
10.1038/s41598-020-76648-4journal_volume
10pub_type
杂志文章abstract：:Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder resulting from mutations in the dystrophin gene. The mdx/utrn -/- mouse, lacking in both dystrophin and its autosomal homologue utrophin, is commonly used to model the clinical symptoms of DMD. Interestingly, these mice are infertile but the mechanisms ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05993-8
更新日期：2017-08-07 00:00:00
abstract：:In this paper, we investigate the unified bound of quantum speed limit time in open systems based on the modified Bures angle. This bound is applied to the damped Jaynes-Cummings model and the dephasing model, and the analytical quantum speed limit time is obtained for both models. As an example, the maximum coherent ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62409-w
更新日期：2020-03-26 00:00:00
abstract：:Loss of olfactomedin 4 (OLFM4) gene expression is associated with the progression of human prostate cancer, but its role and the molecular mechanisms involved in this process have not been completely understood. In this study, we found that Olfm4-knockout mice developed prostatic intraepithelial neoplasia and prostati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16974
更新日期：2015-11-19 00:00:00
abstract：:Psychopathy is a personality disorder characterised by atypical moral behaviour likely rooted in atypical affective/motivational processing, as opposed to an inability to judge the wrongness of an action. Guilt is a moral emotion believed to play a crucial role in adherence to moral and social norms, but the mechanism...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36273
更新日期：2016-11-03 00:00:00
abstract：:We developed a new technique to observe macroautophagy in the brain in vivo, and examined whether fasting induced macroautophagy in neurons and how the induction was different between Alzheimer's disease (AD) model and control mice. Lentivirus for EGFP-LC3 injected into the brain successfully visualized autophagosome ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12115
更新日期：2015-07-14 00:00:00
abstract：:In Taiwan, beginning in 2013, the 13-valent pneumococcal conjugate vaccine (PCV13) was provided free of charge to children 2-5 years of age. In 2014, this was extended to children 1-5 years old. During 2012-2014, 953 cases of culture-confirmed pneumococcal disease (CCPD), including 104 invasive pneumococcal disease (I...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15843
更新日期：2015-11-02 00:00:00
abstract：:The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs, including the inner ear. Point-mutations in the seed sequence of miR-96 result in non-syndromic hearing loss in both mice and humans. However, the lack of a functionally null mutant has hampered the evaluati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36894-z
更新日期：2018-12-21 00:00:00
abstract：:A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, we utilized probes comprising headless, HA stabilized stem (SS) to determine the prevalence, bind...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26538-7
更新日期：2018-06-05 00:00:00
abstract：:Circular Dichroism data are often decomposed into their constituent spectra to quantify the secondary structure of peptides or proteins but the estimation of the secondary structure content fails when light scattering leads to spectral distortion. If peptide-induced liposome self-association occurs, subtracting contro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39450
更新日期：2016-12-22 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep25577. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/srep46944
更新日期：2018-02-16 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-75647-9
更新日期：2020-10-29 00:00:00
abstract：:Apparently mundane, amorphous nanostructures of carbon have optical properties which are as exotic as their crystalline counterparts. In this work we demonstrate a simple and inexpensive mechano-chemical method to prepare bulk quantities of self-passivated, amorphous carbon dots. Like the graphene quantum dots, the wa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28021-9
更新日期：2018-06-27 00:00:00
abstract：:The conservation of plant and animal genetic heritage is not a purpose in itself, but it represents the sine qua non condition for practicing a sustainable agriculture and to ensure nutrition and food security on long-term. Our research focused on identifying the areas with the richest genetic diversity of vegetables ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75413-x
更新日期：2020-10-28 00:00:00
abstract：:Cholangiocarcinoma (CCA) represents a rare form of primary liver cancer with increasing incidence but dismal prognosis. Surgical treatment has remained the only potentially curative treatment option, but it remains unclear which patients benefit most from liver surgery, highlighting the need for new preoperative strat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17175-7
更新日期：2017-12-05 00:00:00
abstract：:The charge transfer from the main catalyst to the cocatalyst is a key factor to enhance catalytic activity for photocatalytic nanocomposite materials. In order to enhance the charge transfer between Bi2WO6 and graphene, we inlet MoS2 as a "stepping-stone" into Bi2WO6 and graphene. Here, we report an effective strategy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03911-6
更新日期：2017-06-16 00:00:00
abstract：:Scientific Reports 7: Article number: 45816; published online: 06 April 2017; updated: 16 May 2017. The original version of this Article contained an error in Affiliation 2, which was incorrectly given as: 'Department of Biophysics, School of Life Sciences, Manipal University, Manipal, 567014, India'. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/srep46803
更新日期：2017-05-16 00:00:00
abstract：:The early replication of some orally-acquired prion strains upon stromal-derived follicular dendritic cells (FDC) within the small intestinal Peyer's patches is essential to establish host infection, and for the disease to efficiently spread to the brain. Factors that influence the early accumulation of prions in Peye...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42900-9
更新日期：2019-04-30 00:00:00
abstract：:The CuO inverse opal photonic crystals (IOPCs) were synthesized by the sol-gel method and modified with CdS quantum dots by successive ionic layer adsorption and reaction (SILAR). CdS QDs modified CuO IOPCs FTO electrodes of different SILAR cycles were fabricated and their electrochemical properties were studied by cy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10838
更新日期：2015-06-04 00:00:00
abstract：:Milk oligosaccharides (MOs) are complex carbohydrates with multifunctional health benefits for the neonate. Poor reproductive performance in primiparous gilts limits their productivity. Changes in the structure and abundance of porcine MO (PMOs) through lactation with parity remains unknown and may explain superior ne...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23025-x
更新日期：2018-03-16 00:00:00
abstract：:Leptin has a central role in the maintenance of energy homeostasis, and its sensitivity is influenced by both the photoperiod and dietary polyphenols. The aim of this study was to investigate the effect of seasonal consumption of polyphenol-rich fruits on the hypothalamic leptin signaling system in non-obese and obese...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31855-y
更新日期：2018-09-11 00:00:00
abstract：:This study aims to evaluate the diagnostic accuracy of digital breast tomosynthesis-guided vacuum assisted breast biopsy (DBT-VABB) of screening detected suspicious mammographic abnormalities comprising of calcifications, asymmetric densities, architectural distortions and spiculated masses. In this institutionally ap...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80124-4
更新日期：2021-01-08 00:00:00
abstract：:Inflammatory and cardiovascular biomarkers have been associated with obesity, but little is known about how they change upon dietary intervention and concomitant weight loss. Further, protein biomarkers might be useful for predicting weight loss in overweight and obese individuals. We performed secondary analyses in t...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41598-020-64636-7
更新日期：2020-05-13 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-019-46788-3
更新日期：2019-07-18 00:00:00
abstract：:Two hundred and six strains of avian infectious bronchitis virus (IBV) were isolated from chickens showing signs of disease in southern China during the period from 2013-2015. The nucleotide and amino acid sequences from the isolated field strains were compared to 42 published references. Nucleotide homologies ranged ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06987-2
更新日期：2017-07-26 00:00:00
abstract：:The aim of the current study is to assess whether total bile acid (TBA) level in first trimester pregnancy is associated with gestational diabetes mellitus (GDM). Biochemical parameters including serum TBA of 742 pregnant women were collected within 12 weeks of gestation and compared. At 24-28th weeks of gestation, 75...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34070
更新日期：2016-09-26 00:00:00
abstract：:The actinopterygians comprise nearly one-half of all extant vertebrate species and are very important for human well-being. However, the phylogenetic relationships among certain groups within the actinopterygians are still uncertain, and debates about these relationships have continued for a long time. Along with the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00665
更新日期：2012-01-01 00:00:00
abstract：:Standard aquatic toxicity tests of chemicals are often limited by the chemicals' water solubility. Liposomes have been widely used in the pharmaceutical industry to overcome poor pharmacokinetics and biodistribution. In this work, liposomes were synthesized and used in an ecotoxicological context, as a tool to assure ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66694-3
更新日期：2020-06-16 00:00:00
abstract：:Duchenne muscular dystrophy (DMD) is a common and severe X-linked myopathy, characterized by muscle degeneration due to altered or absent dystrophin. DMD has no effective cure, and the underlying molecular mechanisms remain incompletely understood. The aim of this study is to investigate the metabolic changes in DMD u...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81090-1
更新日期：2021-01-21 00:00:00
abstract：:We have developed sensitive detection of cancer biomarker vascular endothelial growth factor (VEGF) using the p-n heterojunction comprised of p-type BiOI nanoflakes (NFs) array and n-type TiO2 nanotubes (NTs) array. Due to the unique arrayed structure and the synergy effect of photoelectrochemistry in the formed p-n j...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04426
更新日期：2014-03-21 00:00:00
abstract：:RNaseIII proteins are dsRNA-specific endonucleases involved in many important biological processes, such as small RNA processing and maturation in eukaryotes. Various small RNAs have been identified in a protozoan parasite Entamoeba histolytica. EhRNaseIII is the only RNaseIII endonuclease domain (RIIID)-containing pr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44832
更新日期：2017-03-20 00:00:00
