MicroRNA-mediated mRNA translation activation in quiescent cells and oocytes involves recruitment of a nuclear microRNP.

abstract：:Since the spring 2018, a large part of Europe has been in the midst of a record-setting drought. Using long-term observations, we demonstrate that the occurrence of the 2018-2019 (consecutive) summer drought is unprecedented in the last 250 years, and its combined impact on the growing season vegetation activities is ...

journal_title：Scientific reports

authors： Hari V,Rakovec O,Markonis Y,Hanel M,Kumar R

更新日期：2020-08-06 00:00:00

abstract：:Climatic changes can induce geographic expansion and altitudinal shifts in the distribution of invasive species by offering more thermally suitable habitats. At the remote sub-Antarctic Kerguelen Islands, the predatory insect Merizodus soledadinus (Coleoptera: Carabidae), introduced in 1913, rapidly invaded coastal ha...

journal_title：Scientific reports

authors： Ouisse T,Day E,Laville L,Hendrickx F,Convey P,Renault D

更新日期：2020-01-27 00:00:00

abstract：:Infantile hemangioma is the most common benign tumor in infants. Many studies have confirmed that basic fibroblast growth factor (bFGF) and its key receptor FGFR1 are highly expressed in hemangioma. Moreover, several miRNAs can regulate angiogenesis. In this regard, miR-424 often plays a role as tumor suppressor gene....

journal_title：Scientific reports

authors： Yang L,Dai J,Li F,Cheng H,Yan D,Ruan Q

更新日期：2017-09-19 00:00:00

abstract：:The Frasnian-Famennian boundary records one of the most catastrophic mass extinctions of the Phanerozoic Eon. Several possible causes for this extinction have been suggested, including extra-terrestrial impacts and large-scale volcanism. However, linking the extinction with these potential causes is hindered by the la...

journal_title：Scientific reports

authors： Percival LME,Davies JHFL,Schaltegger U,De Vleeschouwer D,Da Silva AC,Föllmi KB

更新日期：2018-06-22 00:00:00

abstract：:PC4 is an abundant single-strand DNA binding protein that has been implicated in transcription and DNA repair. Here, we show that PC4 is involved in the cellular DNA damage response. To elucidate the role, we used the DT40 chicken B cell model, which produces clustered DNA lesions at Ig loci via the action of activati...

journal_title：Scientific reports

authors： Caldwell RB,Braselmann H,Schoetz U,Heuer S,Scherthan H,Zitzelsberger H

更新日期：2016-07-04 00:00:00

abstract：:With new degrees of freedom to achieve full control of the optical wavefront, metasurfaces could overcome the fabrication embarrassment faced by the metamaterials. In this paper, a broadband hologram using metasurface consisting of elongated nanoapertures array with different orientations has been experimentally demon...

journal_title：Scientific reports

authors： Zhang X,Jin J,Wang Y,Pu M,Li X,Zhao Z,Gao P,Wang C,Luo X

更新日期：2016-01-28 00:00:00

abstract：:Diet composition impacts metabolic and cardiovascular health with high caloric diets contributing to obesity related disorders. Dietary interventions such as caloric restriction exert beneficial effects in the cardiovascular system, but alteration of which specific nutrient is responsible is less clear. This study inv...

journal_title：Scientific reports

authors： Hennig M,Ewering L,Pyschny S,Shimoyama S,Olecka M,Ewald D,Magarin M,Uebing A,Thierfelder L,Jux C,Drenckhahn JD

更新日期：2019-10-22 00:00:00

abstract：:Although differentiated thyroid carcinoma (DTC) has a good prognosis and survival rate, long-term medication and recurrence monitoring might be needed. The factors that affect postoperative health-related quality of life (HRQoL) in patients with DTC in different regions remain unclear or conflicting. The purpose of th...

journal_title：Scientific reports

authors： Li J,Zhang B,Bai Y,Liu Y,Zhang B,Jin J

更新日期：2020-04-01 00:00:00

abstract：:Here we report a high efficiency photocatalyst, i.e., Mn(2+)-doped and N-decorated ZnO nanofibers (NFs) enriched with vacancy defects, fabricated via electrospinning and a subsequent controlled annealing process. This nanocatalyst exhibits excellent visible-light photocatalytic activity and an apparent quantum efficie...

journal_title：Scientific reports

authors： Wang Y,Cheng J,Yu S,Alcocer EJ,Shahid M,Wang Z,Pan W

更新日期：2016-09-07 00:00:00

abstract：:The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding the SMYD1 promoter, participates in various cellular processes and is involved in human cancers. We report the first crystal structures of the human HDGF PWWP domain (residues 1-100) in a comp...

journal_title：Scientific reports

authors： Chen LY,Huang YC,Huang ST,Hsieh YC,Guan HH,Chen NC,Chuankhayan P,Yoshimura M,Tai MH,Chen CJ

更新日期：2018-01-10 00:00:00

abstract：:The rapid increase in use of electronic-cigarettes (e-cigarettes), especially among youth, raises the urgency for regulating bodies to make informed decisions, guidance, and policy on these products. This study evaluated cardiac function in an experimental model following exposure to e-cigarettes. We subjected C57BL/6...

journal_title：Scientific reports

authors： Shi H,Fan X,Horton A,Haller ST,Kennedy DJ,Schiefer IT,Dworkin L,Cooper CJ,Tian J

更新日期：2019-03-11 00:00:00

abstract：:In many cancers, the establishment of a patient's future treatment regime often relies on histopathological assessment of tumor tissue specimens in order to determine the extent of the 'pathological response' to a given therapy. However, histopathological assessment of pathological response remains subjective. Here we...

journal_title：Scientific reports

authors： Patterson NH,Alabdulkarim B,Lazaris A,Thomas A,Marcinkiewicz MM,Gao ZH,Vermeulen PB,Chaurand P,Metrakos P

更新日期：2016-11-14 00:00:00

abstract：:Spatially explicit information on electric power consumption (EPC) is crucial for effective electricity allocation and utilization. Many studies have estimated fine-scale spatial EPC based on remotely sensed nighttime light (NTL). However, the spatial non-stationary relationship between EPC and NTL at prefectural leve...

journal_title：Scientific reports

authors： Chen M,Cai H,Yang X,Jin C

更新日期：2020-10-29 00:00:00

abstract：:Current research on the influence of environmental and physicochemical factors in shaping the soil bacterial structure has seldom been approached from a pedological perspective. We studied the bacterial communities of eight soils selected along a pedogenic gradient at the local scale in a Mediterranean calcareous moun...

journal_title：Scientific reports

authors： Sánchez-Marañón M,Miralles I,Aguirre-Garrido JF,Anguita-Maeso M,Millán V,Ortega R,García-Salcedo JA,Martínez-Abarca F,Soriano M

更新日期：2017-11-06 00:00:00

abstract：:Hyperlipidemia, a very common disease throughout the world, usually gives rise to severe liver damages. The current experiment was to investigate the antihyperlipidemic and hepatoprotective properties of alkali- and enzyme-extractable Dictyophora indusiata polysaccharides (Al-DPS and En-DPS) on the hyperlipidemic mice...

journal_title：Scientific reports

authors： Wang W,Liu H,Zhang Y,Feng Y,Yuan F,Song X,Gao Z,Zhang J,Song Z,Jia L

更新日期：2019-10-03 00:00:00

abstract：:We report a water decomposition mode called 'Aquaionic Splitting (AiS)' by means of iron corrosion in aqueous solution. In this paper, we investigated the phenomenon by controlling the reaction between iron and water. A pseudo-sacrificial protection method with oil paint was employed to select the anode and cathode fo...

journal_title：Scientific reports

authors： Murakami S,Zhang L,Watanabe S

更新日期：2020-02-03 00:00:00

abstract：:We investigated how skeletal muscle mass (SMM) affects spinal sagittal balance (radiographic parameters) in symptomatic spinal patients. The first purpose of this study was to evaluate the body composition and the spinal sagittal alignment in symptomatic spinal patients. The second purpose of this study was to compare...

journal_title：Scientific reports

authors： Hiyama A,Katoh H,Sakai D,Sato M,Tanaka M,Nukaga T,Watanabe M

更新日期：2018-10-19 00:00:00

abstract：:Ginseng rusty root (GRR) symptom is one of the primary diseases of ginseng. There has been a problem of ginseng rusty root, leading to a severe decline in the quality of ginseng. To clarify the relationship between root symptoms of ginseng rust and soil, the physical and chemical properties, enzyme activity, community...

journal_title：Scientific reports

authors： Bian X,Xiao S,Zhao Y,Xu Y,Yang H,Zhang L

更新日期：2020-09-25 00:00:00

abstract：:Effects of elevated seawater temperatures on deep-water benthos has been poorly studied, despite reports of increased seawater temperature (up to 4 °C over 24 hrs) coinciding with mass mortality events of the sponge Geodia barretti at Tisler Reef, Norway. While the mechanisms driving these mortality events are unclear...

journal_title：Scientific reports

authors： Strand R,Whalan S,Webster NS,Kutti T,Fang JKH,Luter HM,Bannister RJ

更新日期：2017-05-22 00:00:00

abstract：:Respiratory Distress Syndrome (RDS) is the commonest diagnosis after premature birth. We aimed to audit clinical practices before and after introduction of a national guideline in Wales on RDS management. Anonymised, prospective data on all infants born at <34 weeks of gestation and cared for at one of the participati...

journal_title：Scientific reports

authors： Course C,Chakraborty M

更新日期：2020-02-26 00:00:00

abstract：:Mitochondrial genomes exhibit diverse features among eukaryotes in the aspect of gene content, genome structure, and the mobile genetic elements such as introns and plasmids. Although the number of published mitochondrial genomes is increasing at tremendous speed, those of several lineages remain unexplored. Here, we ...

journal_title：Scientific reports

authors： Nishimura Y,Shiratori T,Ishida KI,Hashimoto T,Ohkuma M,Inagaki Y

更新日期：2019-03-19 00:00:00

abstract：:A fundamental strategy to enhance optical transmission through a continuous metallic film based on strong interference dominated by interface phase shift is developed. In a metallic film coated with a thin semiconductor film, both transmission and absorption are simultaneously enhanced as a result of dramatically redu...

journal_title：Scientific reports

authors： Li Q,Du K,Mao K,Fang X,Zhao D,Ye H,Qiu M

更新日期：2016-07-12 00:00:00

abstract：:Precision medicine is continuously demanding for novel point of care systems, potentially exploitable also for in-vivo analysis. Biosensing probes based on Lab-On-Fiber Technology have been recently developed to meet these challenges. However, devices exploiting standard label-free approaches (based on ligand/target m...

journal_title：Scientific reports

authors： Aliberti A,Ricciardi A,Giaquinto M,Micco A,Bobeico E,La Ferrara V,Ruvo M,Cutolo A,Cusano A

更新日期：2017-10-31 00:00:00

abstract：:The progression of pulmonary fibrosis (PF) entails a complex network of interactions between multiple classes of molecules and cells, which are closely related to the vagus nerve. Stimulation of the vagus nerve increases fibrogenic cytokines in humans, therefore, activation of the nerve may promote PF. The hypothesis ...

journal_title：Scientific reports

authors： Song N,Liu J,Shaheen S,Du L,Proctor M,Roman J,Yu J

更新日期：2015-08-20 00:00:00

abstract：:The poor bonding strength between biopolymer and bioceramic has remained an unsolved issue. In this study, graphene oxide (GO) was introduced as an interface phase to improve the interfacial bonding between polyetheretherketone (PEEK) and hydroxyapatite (HAP) for tissue engineering scaffolds. On the one hand, the conj...

journal_title：Scientific reports

authors： Peng S,Feng P,Wu P,Huang W,Yang Y,Guo W,Gao C,Shuai C

更新日期：2017-04-20 00:00:00

abstract：:Liquid biopsy can provide a strong basis for precision medicine. We aimed to identify novel single-nucleotide variants (SNVs) in circulating tumor DNA (ctDNA) in patients with hepatocellular carcinoma (HCC). Deep sequencing of plasma-derived ctDNA from 59 patients with HCC was performed using a panel of 2924 SNVs in 6...

journal_title：Scientific reports

authors： Kim SS,Eun JW,Choi JH,Woo HG,Cho HJ,Ahn HR,Suh CW,Baek GO,Cho SW,Cheong JY

更新日期：2020-10-20 00:00:00

abstract：:Semisynthetic cephalosporins are widely used antibiotics currently produced by different chemical steps under harsh conditions, which results in a considerable amount of toxic waste. Biocatalytic synthesis by the cephalosporin acylase from Pseudomonas sp. strain N176 is a promising alternative. Despite intensive engin...

journal_title：Scientific reports

authors： Ferrario V,Fischer M,Zhu Y,Pleiss J

更新日期：2019-08-27 00:00:00

abstract：:Diabetic nephropathy, the major cause of chronic kidney disease, is associated with progressive renal fibrosis. Recently, accumulation of periostin, an extracellular matrix protein, was shown to augment renal fibrosis. Aptamers have higher binding affinities without developing the common side effects of antibodies. Th...

journal_title：Scientific reports

authors： Um JE,Park JT,Nam BY,Lee JP,Jung JH,Kim Y,Kim S,Park J,Wu M,Han SH,Yoo TH,Kang SW

更新日期：2017-08-17 00:00:00

abstract：:Haematopoietic cells arise from endothelial cells within the dorsal aorta of the embryo via a process called the endothelial-haematopoietic transition (EHT). This process crucially depends on the transcription factor RUNX1 which rapidly activates the expression of genes essential for haematopoietic development. Using ...

journal_title：Scientific reports

authors： Gilmour J,Assi SA,Noailles L,Lichtinger M,Obier N,Bonifer C

更新日期：2018-07-10 00:00:00

abstract：:Single epitaxially-grown semiconductor quantum dots have great potential as single photon sources for photonic quantum technologies, though in practice devices often exhibit nonideal behavior. Here, we demonstrate that amplitude modulation can improve the performance of quantum-dot-based sources. Starting with a brigh...

journal_title：Scientific reports

authors： Ates S,Agha I,Gulinatti A,Rech I,Badolato A,Srinivasan K

更新日期：2013-01-01 00:00:00