Abstract:
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Frost HK,Andersson T,Johansson S,Englund-Johansson U,Ekström P,Dahlin LB,Johansson Fdoi
10.1038/s41598-019-44658-6subject
Has Abstractpub_date
2019-07-05 00:00:00pages
10017issue
1issn
2045-2322pii
10.1038/s41598-019-44658-6journal_volume
9pub_type
已发布勘误abstract::In glaucoma, retinal ganglion cells degenerate progressively, leading to visual field loss and blindness. Presently, the only treatment strategy for glaucoma is lowering the intraocular pressure. However, there are cases in which patients develop progressive visual field loss even though their intraocular pressures ar...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78731-2
更新日期:2020-12-10 00:00:00
abstract::Bark beetles often serve as forest damaging agents, causing landscape-level mortality. Understanding the biology and ecology of beetles are important for both, gathering knowledge about important forest insects and forest protection. Knowledge about the bark beetle gut-associated bacteria is one of the crucial yet sur...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75203-5
更新日期:2020-10-29 00:00:00
abstract::A biochemical reaction model clarifies for the first time how cold atmospheric plasmas (CAPs) affect mitochondrial redox homeostasis and energy metabolism. Fundamental mitochondrial functions in pyruvic acid oxidation, the tricarboxylic acid (TCA) cycle and oxidative phosphorylation involving the respiratory chain (RC...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53219-w
更新日期:2019-11-20 00:00:00
abstract::There is an urgent need for sensors deployed during focal therapies to inform treatment planning and in vivo monitoring in thin tissues. Specifically, the measurement of thermal properties, cooling surface contact, tissue thickness, blood flow and phase change with mm to sub mm accuracy are needed. As a proof of princ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21395
更新日期:2016-02-26 00:00:00
abstract::Lipolysis-stimulated lipoprotein receptor (LSR) is a unique molecule of tricellular contacts of normal and cancer cells. We investigated how the loss of LSR induced cell migration, invasion and proliferation in endometrial cancer cell line Sawano. mRNAs of amphiregulin (AREG) and TEA domain family member 1 (TEAD1) wer...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37049
更新日期:2017-01-10 00:00:00
abstract::While Brassica oleracea vegetables have been linked to cancer prevention, the exact mechanism remains unknown. Regulation of gene expression by cross-species microRNAs has been previously reported; however, its link to cancer suppression remains unexplored. In this study we address both issues. We confirm plant microR...
journal_title:Scientific reports
pub_type: 杂志文章,收录出版
doi:10.1038/srep32773
更新日期:2016-09-08 00:00:00
abstract::A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-017-14857-0
更新日期:2017-11-16 00:00:00
abstract::Induction of cathelicidin-mediated antimicrobial pathway against intracellular M. tuberculosis by 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), the active form of vitamin D, has been documented in vitro. However, in in vivo studies related to inflammatory disorders, 1,25(OH)2D3 has been demonstrated to induce an anti-inflam...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34469
更新日期:2016-10-04 00:00:00
abstract::TRPA1 is a Ca2+-permeable ion channel involved in many sensory disorders such as pain, itch and neuropathy. Notably, the function of TRPA1 depends on Ca2+, with low Ca2+ potentiating and high Ca2+ inactivating TRPA1. However, it remains unknown how Ca2+ exerts such contrasting effects. Here, we show that Ca2+ regulate...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45098
更新日期:2017-03-23 00:00:00
abstract::Globally, Aedes aegypti is one of the most dangerous mosquitoes that plays a crucial role as a vector for human diseases, such as yellow fever, dengue, and chikungunya. To identify (1) transcriptomic basis of midgut (2) key genes that are involved in the toxicity process by a comparative transcriptomic analysis betwee...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30741-x
更新日期:2018-08-23 00:00:00
abstract::In this study, 44 compounds in the petroleum ether extract of Maqian (Zanthoxylum myriacanthum var. pubescens) bark, a traditional Dai herbal medicine, were identified by GC-MS. Major components included 3(2H)-benzofuranone, asarinin and (dimethoxymethyl)-3-methoxy-benzene. A total of 18 compounds were isolated from t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45805
更新日期:2017-04-06 00:00:00
abstract::Lightweight, simple and flexible self-powered photodetectors are urgently required for the development and application of advanced optical systems for the future of wearable electronic technology. Here, using a low-temperature reduction process, we report a chemical approach for producing freestanding monolithic reduc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33525
更新日期:2016-09-16 00:00:00
abstract::Geographic variation in aridity determines environmental productivity patterns, including large-scale variability in pathogens, vectors and associated diseases. If disease risk decreases with increasing aridity and is matched by immune defense, we predict a decrease in innate immune function along a gradient of increa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62806-1
更新日期:2020-04-03 00:00:00
abstract::Asymmetric transmission (AT) devices are fundamental elements for optical computing and information processing. We here propose an AT device consisting of a pair of coupled complementary subwavelength gratings. Different from previous works, asymmetric dielectric environment is employed for unidirectional excitation o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53586-4
更新日期:2019-11-19 00:00:00
abstract::Extracellular vesicles (EVs) play an important role in the transfer of biomolecules between cells. To elucidate the intercellular transfer fate of EVs in vivo, we generated a new transgenic (Tg) rat model using green fluorescent protein (GFP)-tagged human CD63. CD63 protein is highly enriched on EV membranes via traff...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31172
更新日期:2016-08-19 00:00:00
abstract::Angiosperm mitochondrial genomes (mtDNA) exhibit variable quantities of alien sequences. Many of these sequences are acquired by intracellular gene transfer (IGT) from the plastid. In addition, frequent events of horizontal gene transfer (HGT) between mitochondria of different species also contribute to their expanded...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43402
更新日期:2017-03-06 00:00:00
abstract::Recent reports have demonstrated the role of phyto-constituents in modulating inflammatory responses. Mangiferin isolated from Mangifera indica is known to induce potent anti-oxidative, anti-diabetic and anti-inflammatory activity. However, the molecular mechanism of its anti-inflammatory activity is not properly unde...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42683
更新日期:2017-02-20 00:00:00
abstract::2,5-Dimethylfuran (DMF) is a type of attractive sustainable green energy for diesel engines that is designed to reduce soot emission. This study investigated the effect of fuel properties on the macroscopic and microscopic spray characteristics of four test blends under injection pressures of 90, 120 and 150 MPa and a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58119-y
更新日期:2020-01-29 00:00:00
abstract::The influence of meteorological determinants on tuberculosis (TB) incidence remains severely under-discussed, especially through the perspective of time series analysis. In the current study, we used a distributed lag nonlinear model (DLNM) to analyze a 10-year series of consecutive surveillance data. We found that, a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28426-6
更新日期:2018-07-03 00:00:00
abstract::This manuscript presents a detailed characterization of active control of bow shock waves via leading edge injection, including subsonic coolant ejection and the appearance of Coanda effects. The flow phenomena occurring at steady and pulsating flow injection regimes were analyzed using steady and unsteady two-dimensi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79048-w
更新日期:2020-12-14 00:00:00
abstract::Natural variability in pH in the diffusive boundary layer (DBL), the discrete layer of seawater between bulk seawater and the outer surface of organisms, could be an important factor determining the response of corals and coralline algae to ocean acidification (OA). Here, two corals with different morphologies and one...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49044-w
更新日期:2019-09-06 00:00:00
abstract::Gait speed in laboratory settings (in-laboratory gait speed) is one of the important indicators associated with the decline in functional abilities in older adulthood. Recently, it has become possible to measure gait speed during daily living (daily gait speed) using accelerometers. However, the relationship between t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39695-0
更新日期:2019-03-05 00:00:00
abstract::MBL2 gene encodes mannose-binding lectin, is a member of innate immune system. Earlier studies revealed that MBL2 gene variants, rs1800451, rs1800450, rs5030737, rs7096206, rs11003125 and rs7095891 are associated with impaired serum level and susceptibility to TB, but their results are inconsistent. A meta-analysis wa...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析,评审
doi:10.1038/srep35728
更新日期:2016-11-23 00:00:00
abstract::Galectin-3 is a biomarker of fibrosis, inflammation and oxidative stress, and its role in heart remodelling and exercise intolerance has not been conclusively proven in heart failure (HF) patients with reduced ejection fraction (rEF). We prospectively assessed 67 consecutive patients with symptomatic HF and left ventr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73634-8
更新日期:2020-10-07 00:00:00
abstract::Prestin in the lateral membrane of outer hair cells, is responsible for electromotility (EM) and a corresponding nonlinear capacitance (NLC). Prestin's voltage sensitivity is influenced by intracellular chloride. A regulator of intracellular chloride is a stretch-sensitive, non-selective conductance within the lateral...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46619
更新日期:2017-04-19 00:00:00
abstract::Insulin measurements are not advised for cardiometabolic risk screening in large groups. Here we assessed the accuracy of the single-point insulin sensitivity estimator (SPISE) to diagnose cardiometabolic risk in Chilean adolescents. In 678 post-pubertal adolescents (52% males, M(SD) age = 16.8 (0.2) years), height, w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71074-y
更新日期:2020-09-01 00:00:00
abstract::High quality factor (High-Q) and transmission optical devices are required for various applications in the fields of physics and engineering. Critical for these applications is the realization of a structure with high-Q, complete transmission and small volume. A robust high-Q filter with complete transmission by conju...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64076-3
更新日期:2020-04-27 00:00:00
abstract::We previously found that Homeobox containing 1 (HMBOX1) was required for bone mesenchymal stem cell (BMSC) and mouse embryonic stem cell (ESC) differentiation into vascular endothelial cells (VECs). However, the function of HMBOX1 in VECs is still unknown. In this study, we found that HMBOX1 was abundantly expressed i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15121
更新日期:2015-10-12 00:00:00
abstract::Geometric frustration, in which competing interactions give rise to degenerate ground states, potentially induces various exotic quantum phenomena in magnetic materials. Minimal models comprising triangular units, such as triangular and Kagome lattices, have been investigated for decades to realize novel quantum phase...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15327
更新日期:2015-10-15 00:00:00
abstract::The mitogen-activated protein kinase (MAPK) cascades, which play crucial roles in plant development processes, are universal modules of signal transduction in eukaryotes and consist of a core module of three sequentially phosphorylated kinases: MAPK, MAPK kinase (MAPKK), and MAPKK kinase (MAPKKK). This is the first re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17615-4
更新日期:2017-12-18 00:00:00