Relationship between Daily and In-laboratory Gait Speed among Healthy Community-dwelling Older Adults.

abstract：:Disseminated tumor cells (DTCs) in the bone marrow (BM) and circulating tumor cells (CTCs) in blood of breast cancer patients (pts) are known to correlate with worse outcome. Here we demonstrate a different prognostic value of DTCs and CTCs and explain these findings by early clodronate intake. CTCs (n = 376 pts) were...

journal_title：Scientific reports

authors： Kasimir-Bauer S,Reiter K,Aktas B,Bittner AK,Weber S,Keller T,Kimmig R,Hoffmann O

更新日期：2016-05-23 00:00:00

abstract：:Antiretroviral therapy-naive HIV-1 infected infants experience poor viral containment and rapid disease progression compared to adults. Viral factors (e.g. transmitted cytotoxic T- lymphocyte (CTL) escape mutations) or infant factors (e.g. reduced CTL functional capacity) may explain this observation. We assessed CTL ...

journal_title：Scientific reports

authors： Garcia-Knight MA,Slyker J,Payne BL,Pond SL,de Silva TI,Chohan B,Khasimwa B,Mbori-Ngacha D,John-Stewart G,Rowland-Jones SL,Esbjörnsson J

更新日期：2016-07-12 00:00:00

abstract：:Across the planet the biogeographic distribution of human cultural diversity tends to correlate positively with biodiversity. In this paper we focus on the biogeographic distribution of mammal species and human cultural diversity. We show that not only are these forms of diversity similarly distributed in space, but t...

journal_title：Scientific reports

authors： Hamilton MJ,Walker RS,Kempes CP

更新日期：2020-11-12 00:00:00

abstract：:The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required. In order to identify new candidates as potential drug targets, we combined large-scale transposon mutagenesis data analysis and bioinforma...

journal_title：Scientific reports

authors： Fernández-Piñar R,Lo Sciuto A,Rossi A,Ranucci S,Bragonzi A,Imperi F

更新日期：2015-12-01 00:00:00

abstract：:Tyrosine hydroxylase (TH), the initial enzyme in the melanin pathway, catalyzes tyrosine conversion into Dopa. Although expression and regulation of TH have been shown to affect cuticle pigmentation in insects, no direct functional studies to date have focused on the specific physiological processes involving the enzy...

journal_title：Scientific reports

authors： Qiao L,Du M,Liang X,Hao Y,He X,Si F,Mei T,Chen B

更新日期：2016-07-15 00:00:00

abstract：:Conventional disease animal models have limitations on the conformity to the actual clinical situation. Disease-syndrome combination (DS) modeling may provide a more efficient strategy for biomedicine research. Disease model and DS model of renal fibrosis in chronic kidney disease were established by ligating the left...

journal_title：Scientific reports

authors： Li S,Xu P,Han L,Mao W,Wang Y,Luo G,Yang N

更新日期：2017-08-18 00:00:00

abstract：:Sharp declines in numerous shark populations around the world have generated considerable interest in better understanding and characterising their biology, ecology and critical habitats. The scalloped hammerhead shark (SHS, Sphyrna lewini) is subject to a multitude of natural and anthropogenic threats that are often ...

journal_title：Scientific reports

authors： Marie AD,Miller C,Cawich C,Piovano S,Rico C

更新日期：2017-12-08 00:00:00

abstract：:The Martian outflow channels comprise some of the largest known channels in the Solar System. Remote-sensing investigations indicate that cataclysmic floods likely excavated the channels ~3.4 Ga. Previous studies show that, in the southern circum-Chryse region, their flooding pathways include hundreds of kilometers of...

journal_title：Scientific reports

authors： Rodriguez JAP,Baker VR,Liu T,Zarroca M,Travis B,Hui T,Komatsu G,Berman DC,Linares R,Sykes MV,Banks ME,Kargel JS

更新日期：2019-02-25 00:00:00

abstract：:Chronic kidney disease (CKD) is a public health problem that increases the risk of cardiovascular morbidity and mortality. Heart failure with preserved ejection fraction (HFpEF) characterized by left ventricular hypertrophy (LVH) and diastolic dysfunction is a common cardiovascular complication of CKD. MicroRNA-212 (m...

journal_title：Scientific reports

authors： Sárközy M,Gáspár R,Zvara Á,Siska A,Kővári B,Szűcs G,Márványkövi F,Kovács MG,Diószegi P,Bodai L,Zsindely N,Pipicz M,Gömöri K,Kiss K,Bencsik P,Cserni G,Puskás LG,Földesi I,Thum T,Bátkai S,Csont T

更新日期：2019-02-04 00:00:00

abstract：:Intermediate level radioactive waste (ILW) generally contains a heterogeneous range of organic and inorganic materials, of which some are encapsulated in cement. Of particular concern are cellulosic waste items, which will chemically degrade under the conditions predicted during waste disposal, forming significant qua...

journal_title：Scientific reports

authors： Kuippers G,Boothman C,Bagshaw H,Ward M,Beard R,Bryan N,Lloyd JR

更新日期：2018-06-08 00:00:00

abstract：:Insecticides and other agrochemicals have become indispensable components of the agricultural system to ensure a notable increase in crop yield and food production. As a natural consequence, chemical residues result in significantly increased contamination of both terrestrial and aquatic ecosystems. The present study ...

journal_title：Scientific reports

authors： Basal WT,Ahmed ART,Mahmoud AA,Omar AR

更新日期：2020-11-11 00:00:00

abstract：:The mouse (Mus musculus) is an extensively used model of human disease and responses to stresses such as ionizing radiation. As part of our work developing gene expression biomarkers of radiation exposure, dose, and injury, we have found many genes are either up-regulated (e.g. CDKN1A, MDM2, BBC3, and CCNG1) or down-r...

journal_title：Scientific reports

authors： Ghandhi SA,Smilenov L,Shuryak I,Pujol-Canadell M,Amundson SA

更新日期：2019-12-19 00:00:00

abstract：:The Smacoviridae has recently been classified as a family of small circular single-stranded DNA viruses. An increasing number of smacovirus genomes have been identified exclusively in faecal matter of various vertebrate species and from insect body parts. However, the genetic diversity and host range of smacoviruses r...

journal_title：Scientific reports

authors： Anindita PD,Sasaki M,Gonzalez G,Phongphaew W,Carr M,Hang'ombe BM,Mweene AS,Ito K,Orba Y,Sawa H

更新日期：2019-04-08 00:00:00

abstract：:Nesfatin-1, a satiety molecule processed from nucleobindin2 (NUCB2), is implicated in visceral hypersensitivity in rats and colocalized with 5-hydroxytryptamine (5-HT) in the dorsal raphe nucleus (DRN). Maternal separation (MS) in rats contributes to visceral hypersensitivity via elevated expression of 5-HT in the DRN...

journal_title：Scientific reports

authors： Zhang HA,Sang N,Ge X,Huang Q,Li XL,Sha J

更新日期：2018-06-19 00:00:00

abstract：:Intestinal-type sinonasal adenocarcinoma (ITAC) is a rare tumor carrying poor prognosis and needing new treatment options. The aim of this study was to identify actionable gene mutations that can guide new personalized target-specific therapies in ITAC patients. A series of 48 tumor and 27 corresponding germline DNA s...

journal_title：Scientific reports

authors： Sánchez-Fernández P,Riobello C,Costales M,Vivanco B,Cabal VN,García-Marín R,Suárez-Fernández L,López F,Cabanillas R,Hermsen MA,Llorente JL

更新日期：2021-01-26 00:00:00

abstract：:Male specific DNA sequences were selected from a Diversity Arrays Technology (DArT) mapping study to evaluate their suitability for determination of the sex phenotype among young seedlings in a hop (Humulus lupulus L.) breeding program. Ten male specific DArT markers showed complete linkage with male sex phenotype in ...

journal_title：Scientific reports

authors： Čerenak A,Kolenc Z,Sehur P,Whittock SP,Koutoulis A,Beatson R,Buck E,Javornik B,Škof S,Jakše J

更新日期：2019-10-02 00:00:00

abstract：:The psychrophilic (cold-loving) fungus Pseudogymnoascus destructans was discovered more than a decade ago to be the pathogen responsible for white-nose syndrome, an emerging disease of North American bats causing unprecedented population declines. The same species of fungus is found in Europe but without associated mo...

journal_title：Scientific reports

authors： Ren P,Rajkumar SS,Zhang T,Sui H,Masters PS,Martinkova N,Kubátová A,Pikula J,Chaturvedi S,Chaturvedi V

更新日期：2020-08-17 00:00:00

abstract：:There remain parts of our planet that are seldom visited by humans, let alone scientists. In such locations, crowd-sourced or citizen scientist data can be critical in describing biodiversity and detecting change. Rangitāhua, the Kermadec Islands, are 750 km from the nearest human-habitation. Although our knowledge of...

journal_title：Scientific reports

authors： Liggins L,Sweatman JA,Trnski T,Duffy CAJ,Eddy TD,Aguirre JD

更新日期：2020-02-21 00:00:00

abstract：:The glycocalyx regulates the interaction of mammalian cells with extracellular molecules, such as cytokines. However, it is unknown to which extend the glycocalyx of distinct cancer cells control the binding and uptake of nanoparticles. In the present study, exome sequencing data of cancer patients and analysis of dis...

journal_title：Scientific reports

authors： von Palubitzki L,Wang Y,Hoffmann S,Vidal-Y-Sy S,Zobiak B,Failla AV,Schmage P,John A,Osorio-Madrazo A,Bauer AT,Schneider SW,Goycoolea FM,Gorzelanny C

更新日期：2020-12-31 00:00:00

abstract：:The exact extent, by which the hydrologic cycle in the Neotropics was affected by external forcing during the last deglaciation, remains poorly understood. Here we present a new paleo-rainfall reconstruction based on high-resolution speleothem δ18O records from the core region of the South American Monsoon System (SAM...

journal_title：Scientific reports

authors： Novello VF,Cruz FW,Vuille M,Stríkis NM,Edwards RL,Cheng H,Emerick S,de Paula MS,Li X,Barreto ES,Karmann I,Santos RV

更新日期：2017-03-10 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Yang HY,Ma D,Liu YR,Hu X,Zhang J,Wang ZH,Di GH,Hu XC,Shao ZM

更新日期：2018-10-12 00:00:00

abstract：:Type I interferons, particularly interferon-alpha (IFN-α), play a vital role in the host's anti-viral defenses by interfering with viral replication. However, the virus rapidly evolves to exploit the IFN-α response for its replication, spread, and pathogenic function. In this study, we attempted to determine IFN-α sus...

journal_title：Scientific reports

authors： Ashokkumar M,Sonawane A,Sperk M,Tripathy SP,Neogi U,Hanna LE

更新日期：2020-02-17 00:00:00

abstract：:Accidental introduction through ballast water and biofouling are currently the main factors responsible for spreading non-indigenous species in the marine realm. In the Southwestern Atlantic, two scleractinian corals, Tubastraea coccinea and T. tagusensis, have been introduced by opportunistic colonization in 1980 and...

journal_title：Scientific reports

authors： Capel KCC,Creed J,Kitahara MV,Chen CA,Zilberberg C

更新日期：2019-09-27 00:00:00

abstract：:Rapid diagnostic tests (RDTs) have been developed to detect influenza A virus for the swift diagnosis and management of patients. However, despite the simplicity and convenience, the low sensitivity of RDTs remains a limitation for their use in point of care testing (POCT). In this study, we developed a rapid fluoresc...

journal_title：Scientific reports

authors： Yu ST,Thi Bui C,Kim DTH,V T Nguyen A,Thi Trinh TT,Yeo SJ

更新日期：2018-09-07 00:00:00

abstract：:There is an increasing appreciation for the role of the human Y chromosome in phenotypic differences between the sexes in health and disease. Previous studies have shown that genetic variation within the Y chromosome is associated with cholesterol levels, which is an established risk factor for atherosclerosis, the un...

journal_title：Scientific reports

authors： Molina E,Chew GS,Myers SA,Clarence EM,Eales JM,Tomaszewski M,Charchar FJ

更新日期：2017-12-01 00:00:00

abstract：:Non-compressible hemorrhage is the most common preventable cause of death on battlefield and in civilian traumatic injuries. We report the use of microsecond pulses of electric current to induce rapid constriction in femoral and mesenteric arteries and veins in rats. Electrically-induced vasoconstriction could be indu...

journal_title：Scientific reports

authors： Mandel Y,Manivanh R,Dalal R,Huie P,Wang J,Brinton M,Palanker D

更新日期：2013-01-01 00:00:00

abstract：:Working memory capacity is incredibly limited and thus it is important to use this resource wisely. Prior knowledge in long-term memory can aid in efficient encoding of information by allowing for the prioritization of novel stimuli over familiar ones. Here we used a full-report procedure in a visual working memory pa...

journal_title：Scientific reports

authors： Bruning AL,Lewis-Peacock JA

更新日期：2020-12-17 00:00:00

abstract：:The eruptive activity of basaltic hotspot volcanoes displays major fluctuations on times scales of years to decades. Theses fluctuations are thought to reflect changes in the rate of mantle melt supply. However, the crustal filter generally masks the mantle processes involved. Here, we show that the cyclic and general...

journal_title：Scientific reports

authors： Vlastélic I,Di Muro A,Bachèlery P,Gurioli L,Auclair D,Gannoun A

更新日期：2018-09-27 00:00:00

abstract：:Cardiac magnetic resonance (CMR) is becoming the imaging modality of choice in multicenter studies where highly reproducible measurements are necessary. The purpose of this study was to assess the effect of comprehensive initial training on reproducibility of quantitative left ventricular (LV) parameters estimated usi...

journal_title：Scientific reports

authors： Lapinskas T,Hireche-Chikaoui H,Zieschang V,Erley J,Stehning C,Gebker R,Giusca S,Korosoglou G,Zaliunas R,Backhaus SJ,Schuster A,Pieske B,Kelle S

更新日期：2019-08-21 00:00:00

abstract：:There is currently a lack of effective drugs to cure recurrent aphthous stomatitis. This study aimed to evaluate the efficacy of probiotics alone or as an adjunct in recurrent aphthous stomatitis (RAS) patients. Seven randomized controlled trials (RCTs) were included, of which three were included in quantitative analy...

journal_title：Scientific reports

authors： Cheng B,Zeng X,Liu S,Zou J,Wang Y

更新日期：2020-12-03 00:00:00