HMBOX1 interacts with MT2A to regulate autophagy and apoptosis in vascular endothelial cells.

abstract：:Several zebrafish strains such as AB, Tübingen (TU), Wild India Kolkata (WIK) and Tupfel long fin (TL) have been established for genetic study. Each strain has its morphological and behavioral traits. Motor traits, however, have not been explored in zebrafish strains. We here applied a treadmill for fish (swimmill) an...

journal_title：Scientific reports

authors： Wakamatsu Y,Ogino K,Hirata H

更新日期：2019-11-08 00:00:00

abstract：:A particular type of miniature ceramic vessel locally known as "veneneras" is occasionally found during archaeological excavations in the Maya Area. To date, only one study of a collection of such containers successfully identified organic residues through coupled chromatography-mass spectrometry methods. That study i...

journal_title：Scientific reports

authors： Zimmermann M,Brownstein KJ,Pantoja Díaz L,Ancona Aragón I,Hutson S,Kidder B,Tushingham S,Gang DR

更新日期：2021-01-15 00:00:00

abstract：:In the central nervous system of vertebrates, cell bodies of neurons are often assembled as nuclei or cellular layers that play specific roles as functional units. The purpose of this work was to selectively highlight such cell assemblies by magnetic resonance imaging using signals from water protons that are associat...

journal_title：Scientific reports

authors： Watanabe T,Wang X,Tan Z,Frahm J

更新日期：2019-03-25 00:00:00

abstract：:Orthogonal aminoacyl-tRNA synthetase/tRNA pairs have emerged as powerful means of site-specifically introducing non-standard amino acids into proteins in vivo. Using amino acids with crosslinking moieties this method allows the identification of transient protein-protein interactions. Here we have introduced a previou...

journal_title：Scientific reports

authors： Huot JL,Shikha S,Schneider A

更新日期：2019-07-25 00:00:00

abstract：:The presence of missing values (MVs) in label-free quantitative proteomics greatly reduces the completeness of data. Imputation has been widely utilized to handle MVs, and selection of the proper method is critical for the accuracy and reliability of imputation. Here we present a comparative study that evaluates the p...

journal_title：Scientific reports

authors： Jin L,Bi Y,Hu C,Qu J,Shen S,Wang X,Tian Y

更新日期：2021-01-19 00:00:00

abstract：:The static synchronous series compensator (SSSC) can add a series reactance to the transmission line, and when it is fed using auxiliary signals, it can participate in damping inter-area oscillations by changing the series reactance. In this paper, the effect of the SSSC on small-signal stability is investigated. The ...

journal_title：Scientific reports

authors： Naderipour A,Abdul-Malek Z,Ramachandaramurthy VK,Miveh MR,Moghaddam MJH,Guerrero JM

更新日期：2020-07-22 00:00:00

abstract：:We demonstrate an ultrahigh-sensitivity gas pressure sensor based on the Fabry-Perot interferometer employing a fiber-tip diaphragm-sealed cavity. The cavity is comprised of a silica capillary and ultrathin silica diaphragm with a thickness of 170 nm, with represents the thinnest silica diaphragm fabricated thus far b...

journal_title：Scientific reports

authors： Liu S,Wang Y,Liao C,Wang Y,He J,Fu C,Yang K,Bai Z,Zhang F

更新日期：2017-04-11 00:00:00

abstract：:Alumina toughened zirconia (ATZ) and zirconia toughened alumina (ZTA) are currently the materials of choice to meet the need for tough, strong, and bioinert ceramics for medical devices. However, the mechanical properties of ZrO2/Al2O3 dispersion ceramics could be considerably increased by reducing the corresponding g...

journal_title：Scientific reports

authors： Bartolomé JF,Smirnov A,Kurland HD,Grabow J,Müller FA

更新日期：2016-02-05 00:00:00

abstract：:The regular rise and fall of the sun resulted in the development of 24-h rhythms in virtually all organisms. In an evolutionary heartbeat, humans have taken control of their light environment with electric light. Humans are highly sensitive to light, yet most people now use light until bedtime. We evaluated the impact...

journal_title：Scientific reports

authors： Cain SW,McGlashan EM,Vidafar P,Mustafovska J,Curran SPN,Wang X,Mohamed A,Kalavally V,Phillips AJK

更新日期：2020-11-05 00:00:00

abstract：:Bovine milk is vital for infant nutrition and is a major component of the human diet. Bovine mastitis is a common inflammatory disease of mammary gland in cattle. It alters the immune profile of the animal and lowers the quality and yield of milk causing huge economic losses to dairy industry. The incidence of sub-cli...

journal_title：Scientific reports

authors： Bathla S,Sindhu A,Kumar S,Dubey SK,Pattnaik S,Rawat P,Chopra A,Dang A,Kaushik JK,Mohanty AK

更新日期：2020-06-09 00:00:00

abstract：:We evaluated the best methods for predicting various infarct core thresholds for endovascular treatment of ischemic stroke using parameters obtained by multiphase computed tomographic angiography (mCTA). Consecutive patients evaluated for endovascular treatment who concomitantly underwent mCTA and stroke magnetic reso...

journal_title：Scientific reports

authors： Lee SJ,Jung WS,Choi MH,Hong JM,Lee JS,Choi JW

更新日期：2019-10-23 00:00:00

abstract：:Helicobacter pylori cagA-positive strains are critically involved in the development of gastric cancer. Upon delivery into gastric epithelial cells via type IV secretion, the cagA-encoded CagA interacts with and thereby perturbs the pro-oncogenic phosphatase SHP2 and the polarity-regulating kinase PAR1b via the tyrosi...

journal_title：Scientific reports

authors： Hashi K,Imai C,Yahara K,Tahmina K,Hayashi T,Azuma T,Miyabe-Nishiwaki T,Sato H,Matsuoka M,Niimi S,Okamoto M,Hatakeyama M

更新日期：2018-10-29 00:00:00

abstract：:Mapping near-field profiles and dynamics of surface plasmon polaritons is crucial for understanding their fundamental optical properties and designing miniaturized photonic devices. This requires a spatial resolution on the sub-wavelength scale because the effective polariton wavelength is shorter than free-space exci...

journal_title：Scientific reports

authors： Du L,Lei DY,Yuan G,Fang H,Zhang X,Wang Q,Tang D,Min C,Maier SA,Yuan X

更新日期：2013-10-29 00:00:00

abstract：:To investigate the applicability of compound specific stable carbon isotope ratios (δ13C) of organics in assessment of their photochemical aging in the atmosphere, batch UV irradiation experiments were conducted on two ambient (anthropogenic and biogenic) aerosol samples in aqueous phase for 0.5-120 h. The irradiated ...

journal_title：Scientific reports

authors： Pavuluri CM,Kawamura K

更新日期：2016-11-04 00:00:00

abstract：:Enzyme replacement therapies have revolutionized patient treatment for multiple rare lysosomal storage diseases but show limited effectiveness for addressing pathologies in "hard-to-treat" organs and tissues including brain and bone. Here we investigate the plant lectin RTB as a novel carrier for human lysosomal enzym...

journal_title：Scientific reports

authors： Acosta W,Ayala J,Dolan MC,Cramer CL

更新日期：2015-09-18 00:00:00

abstract：:Knowledge of brain correlates of postural control is limited by the technical difficulties in performing controlled experiments with currently available neuroimaging methods. Here we present a system that allows the measurement of anticipatory postural adjustment of human legs to be synchronized with the acquisition o...

journal_title：Scientific reports

authors： de Lima-Pardini AC,de Azevedo Neto RM,Coelho DB,Boffino CC,Shergill SS,de Oliveira Souza C,Brant R,Barbosa ER,Cardoso EF,Teixeira LA,Cohen RG,Horak FB,Amaro E Jr

更新日期：2017-02-23 00:00:00

abstract：:Biological N2 fixation (BNF) in the rhizosphere of Podocarpaceae is currently attributed to unspecific diazotrophs with negligible impact on N acquisition. Here, we report specific and high associative BNF in dead cells of root nodules of Lepidothamnus fonkii distributed in ombrotrophic peatlands of Patagonia. BNF of ...

journal_title：Scientific reports

authors： Borken W,Horn MA,Geimer S,Aguilar NA,Knorr KH

更新日期：2016-12-15 00:00:00

abstract：:Acetylcholine binding proteins (AChBPs) are unique spatial homologs of the ligand-binding domains of nicotinic acetylcholine receptors (nAChRs), and they reproduce some pharmacological properties of nAChRs. X-ray crystal structures of AСhBP in complex with α-conotoxins provide important insights into the interactions ...

journal_title：Scientific reports

authors： Lin B,Xu M,Zhu X,Wu Y,Liu X,Zhangsun D,Hu Y,Xiang SH,Kasheverov IE,Tsetlin VI,Wang X,Luo S

更新日期：2016-03-01 00:00:00

abstract：:Appropriate analytical methods are needed for the detection of food authentication. We investigated the applicability of a duplex real-time PCR assay targeting chromosome 1 and two singleplex real-time PCR assays targeting chromosome 9, both published recently, for the qualitative and quantitative determination of wil...

journal_title：Scientific reports

authors： Kaltenbrunner M,Mayer W,Kerkhoff K,Epp R,Rüggeberg H,Hochegger R,Cichna-Markl M

更新日期：2020-10-14 00:00:00

abstract：:The eg-orbital double-exchange mechanism as the core of physics of colossal magnetoresistance (CMR) manganites is well known, which usually covers up the role of super-exchange at the t2g-orbitals. The role of the double-exchange mechanism is maximized in La0.7Ca0.3MnO3, leading to the concurrent metal-insulator trans...

journal_title：Scientific reports

authors： Liu MF,Du ZZ,Xie YL,Li X,Yan ZB,Liu JM

更新日期：2015-04-24 00:00:00

abstract：:Age-related accumulation of ploidy changes is associated with decreased expression of genes controlling chromosome segregation and cohesin functions. To determine the consequences of whole chromosome instability (W-CIN) we down-regulated the spindle assembly checkpoint component BUB1 and the mitotic cohesin SMC1A, and...

journal_title：Scientific reports

authors： Andriani GA,Almeida VP,Faggioli F,Mauro M,Tsai WL,Santambrogio L,Maslov A,Gadina M,Campisi J,Vijg J,Montagna C

更新日期：2016-10-12 00:00:00

abstract：:We evaluated the performance of three PGx panels to estimate biogeographical ancestry: the DMET panel, and the VIP and Preemptive PGx panels described in the literature. Our analysis indicate that the three panels capture quite well the individual variation in admixture proportions observed in recently admixed populat...

journal_title：Scientific reports

authors： Debortoli G,de Araujo GS,Fortes-Lima C,Parra EJ,Suarez-Kurtz G

更新日期：2021-01-13 00:00:00

abstract：:Diet composition impacts metabolic and cardiovascular health with high caloric diets contributing to obesity related disorders. Dietary interventions such as caloric restriction exert beneficial effects in the cardiovascular system, but alteration of which specific nutrient is responsible is less clear. This study inv...

journal_title：Scientific reports

authors： Hennig M,Ewering L,Pyschny S,Shimoyama S,Olecka M,Ewald D,Magarin M,Uebing A,Thierfelder L,Jux C,Drenckhahn JD

更新日期：2019-10-22 00:00:00

abstract：:The whale shark (Rhincodon typus) is an endangered species with a declining global population. The South Ari Atoll Marine Protected Area (SAMPA), Maldives, is one of few locations globally where year-long residency of individuals occurs. This SAMPA aggregation appears to consist almost exclusively of immature males. D...

journal_title：Scientific reports

authors： Harvey-Carroll J,Stewart JD,Carroll D,Mohamed B,Shameel I,Zareer IH,Araujo G,Rees R

更新日期：2021-01-13 00:00:00

abstract：:Smad1, Smad5 and Smad9 (also known as Smad8) are activated by phosphorylation by bone morphogenetic protein (BMP)-bound type I receptor kinases. We examined the role of Smad1, Smad5, and Smad9 by creating constitutively active forms (Smad(DVD)). Transcriptional activity of Smad9(DVD) was lower than that of Smad1(DVD) ...

journal_title：Scientific reports

authors： Tsukamoto S,Mizuta T,Fujimoto M,Ohte S,Osawa K,Miyamoto A,Yoneyama K,Murata E,Machiya A,Jimi E,Kokabu S,Katagiri T

更新日期：2014-12-23 00:00:00

abstract：:Genome-wide experiments to map the DNA-binding locations of transcription-associated factors (TFs) have shown that the number of genes bound by a TF far exceeds the number of possible direct target genes. Distinguishing functional from non-functional binding is therefore a major challenge in the study of transcription...

journal_title：Scientific reports

authors： Banks CJ,Joshi A,Michoel T

更新日期：2016-02-09 00:00:00

abstract：:Nature disasters and terrorist attacks have occurred globally in recent years. Posttraumatic stress disorder (PTSD) has gained increasing attention, but its incidence and comorbidities in the general population are different from those inside the disaster areas. The present study estimated incident PTSD and comorbid d...

journal_title：Scientific reports

authors： Chang JC,Yen AM,Chen HH,Chen SL,Chiu SY,Fann JC,Lee CS

更新日期：2017-01-27 00:00:00

abstract：:The intermolt crustacean Y-organ (YO) maintains a basal state mediated by pulsatile release of molt inhibiting hormone (MIH), a neuropeptide produced in the eyestalk ganglia, inhibiting YO ecdysteroidogenesis. Reduction of MIH results in YO activation and the animal enters premolt. In the crab, Gecarcinus lateralis, m...

journal_title：Scientific reports

authors： Shyamal S,Das S,Guruacharya A,Mykles DL,Durica DS

更新日期：2018-05-09 00:00:00

abstract：:Leukemia cells are superior to hematopoietic cells with a normal differentiation potential in buffering cellular stresses, but the underlying mechanisms for this leukemic advantage are not fully understood. Using CRISPR/Cas9 deletion of the canonical autophagy-essential gene Atg7, we found that erythroleukemia K562 ce...

journal_title：Scientific reports

authors： Wang J,Fang Y,Yan L,Yuan N,Zhang S,Xu L,Nie M,Zhang X,Wang J

更新日期：2016-04-19 00:00:00

abstract：:The search for new therapeutic approaches to Alzheimer disease (AD) is a major goal in medicine and society, also due to the impressive economic and social costs of this disease. In this scenario, biotechnologies play an important role. Here, it is demonstrated that the Radio Electric Asymmetric Conveyer (REAC), an in...

journal_title：Scientific reports

authors： Lorenzini L,Giuliani A,Sivilia S,Baldassarro VA,Fernandez M,Lotti Margotti M,Giardino L,Fontani V,Rinaldi S,Calzà L

更新日期：2016-10-24 00:00:00