Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate.

abstract：:The mechanisms underlying bladder contractile disorders such as overactive bladder are not fully understood, and there is limited understanding of the receptor systems modulating spontaneous bladder contractions. We investigated the potential for histamine to have a role in mediating contractility of the urothelium wi...

journal_title：Scientific reports

authors： Stromberga Z,Chess-Williams R,Moro C

更新日期：2019-03-07 00:00:00

abstract：:Magneto-optical Faraday effect is widely applied in optical devices and is indispensable for optical communications and advanced information technology. However, the bismuth garnet Bi-YIG is only the Faraday material since 1972. Here we introduce (Fe, FeCo)-(Al-,Y-fluoride) nanogranular films exhibiting giant Faraday ...

journal_title：Scientific reports

authors： Kobayashi N,Ikeda K,Gu B,Takahashi S,Masumoto H,Maekawa S

更新日期：2018-03-21 00:00:00

abstract：:Endometrial cancer is the most common gynecologic cancer in the United States and its incidence and mortality has been rising over the past decade. Few treatment options are available for patients with advanced and recurring endometrial cancers. Novel therapies, which are frequently toxic, are difficult to establish i...

journal_title：Scientific reports

authors： Wen W,Lowe G,Roberts CM,Finlay J,Han ES,Glackin CA,Dellinger TH

更新日期：2017-10-06 00:00:00

abstract：:Cell mechanics play a key role in several fundamental biological processes, such as migration, proliferation, differentiation and tissue morphogenesis. In addition, many diseased conditions of the cell are correlated with altered cell mechanics, as in the case of cancer progression. For this there is much interest in ...

journal_title：Scientific reports

authors： Dehoux T,Abi Ghanem M,Zouani OF,Rampnoux JM,Guillet Y,Dilhaire S,Durrieu MC,Audoin B

更新日期：2015-03-03 00:00:00

abstract：:KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current study aimed to design a...

journal_title：Scientific reports

authors： Schelleckes K,Schmitz B,Lenders M,Mewes M,Brand SM,Brand E

更新日期：2018-03-09 00:00:00

abstract：:Anhedonia, the diminished ability to experience pleasure, is a challenging negative symptom in patients with schizophrenia and can be observed in at-risk individuals with schizotypy. Deficits in hedonic processing have been postulated to be related to decreased motivation to engage in potentially rewarding events. It ...

journal_title：Scientific reports

authors： Li X,Li Z,Li K,Zeng YW,Shi HS,Xie WL,Yang ZY,Lui SS,Cheung EF,Leung AW,Chan RC

更新日期：2016-10-18 00:00:00

abstract：:The circuit complexity of quantum qubit system evolution as a primitive problem in quantum computation has been discussed widely. We investigate this problem in terms of qudit system. Using the Riemannian geometry the optimal quantum circuits are equivalent to the geodetic evolutions in specially curved parametrizatio...

journal_title：Scientific reports

authors： Luo MX,Chen XB,Yang YX,Wang X

更新日期：2014-02-10 00:00:00

abstract：:In clinical populations, olfactory abilities parallel executive function, implicating shared neuroanatomical substrates within the ventral prefrontal cortex. In healthy individuals, the relationship between olfaction and personality traits or certain cognitive and behavioural characteristics remains unexplored. We the...

journal_title：Scientific reports

authors： Herman AM,Critchley H,Duka T

更新日期：2018-10-22 00:00:00

abstract：:Hepatocyte spheroids are useful models for mimicking liver phenotypes in vitro because of their three-dimensionality. However, the lack of a biomaterial platform which allows the facile manipulation of spheroid cultures on a large scale severely limits their application in automated high-throughput drug safety testing...

journal_title：Scientific reports

authors： Tasnim F,Singh NH,Tan EKF,Xing J,Li H,Hissette S,Manesh S,Fulwood J,Gupta K,Ng CW,Xu S,Hill J,Yu H

更新日期：2020-03-16 00:00:00

abstract：:Cognitive dysfunction in fibromyalgia has been reported, especially memory. Anodal transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) has been effective in enhancing this function. We tested the effects of eight sessions of tDCS and cognitive training on immediate and delaye...

journal_title：Scientific reports

authors： Santos VSDSD,Zortea M,Alves RL,Naziazeno CCDS,Saldanha JS,Carvalho SDCR,Leite AJDC,Torres ILDS,Souza A,Calvetti PÜ,Fregni F,Caumo W

更新日期：2018-08-20 00:00:00

abstract：:Infestation of phosphine (PH3) resistant insects threatens global grain reserves. PH3 fumigation controls rice weevil (Sitophilus oryzae) but not highly resistant insect pests. Here, we investigated naturally occurring strains of S. oryzae that were moderately resistant (MR), strongly resistant (SR), or susceptible (w...

journal_title：Scientific reports

authors： Kim K,Yang JO,Sung JY,Lee JY,Park JS,Lee HS,Lee BH,Ren Y,Lee DW,Lee SE

更新日期：2019-10-10 00:00:00

abstract：:Oligomerization of protein into specific quaternary structures plays important biological functions, including regulation of gene expression, enzymes activity, and cell-cell interactions. Here, we report the determination of two crystal structures of the Grimontia hollisae (formally described as Vibrio hollisae) therm...

journal_title：Scientific reports

authors： Wang YK,Huang SC,Chang CY,Huang WT,Liao MJ,Yip BS,Chou FP,Li TT,Wu TK

更新日期：2019-07-08 00:00:00

abstract：:SLC30A2 encodes a zinc (Zn) transporter (ZnT2) that imports Zn into vesicles in highly-specialized secretory cells. Numerous mutations and non-synonymous variants in ZnT2 have been reported in humans and in breastfeeding women; ZnT2 variants are associated with abnormally low milk Zn levels and can lead to severe infa...

journal_title：Scientific reports

authors： Lee S,Zhou Y,Gill DL,Kelleher SL

更新日期：2018-02-23 00:00:00

abstract：:Histone deacetylase inhibition (HDACi) has been suggested as a promising approach to bolster TLR-mediated induction of antimicrobial peptides such as human β-defensin 2 (hBD2). In inflammatory bowel disease (IBD), Crohn's disease (CD) patients display an attenuated expression of hBD2 as compared to ulcerative colitis ...

journal_title：Scientific reports

authors： Stebe-Frick S,Ostaff MJ,Stange EF,Malek NP,Wehkamp J

更新日期：2018-08-27 00:00:00

abstract：:Protein-peptide interactions play an important role in major cellular processes, and are associated with several human diseases. To understand and potentially regulate these cellular function and diseases it is important to know the molecular details of the interactions. However, because of peptide flexibility and the...

journal_title：Scientific reports

authors： Johansson-Åkhe I,Mirabello C,Wallner B

更新日期：2019-03-12 00:00:00

abstract：:The therapeutic management and health challenges caused by atrial fibrillation (AF) differ between different groups. The purpose of this study was to investigate the clinical features of patients hospitalized with AF and to explore the use of anticoagulation treatments in Han and Uygur patients in Xinjiang, northwest ...

journal_title：Scientific reports

authors： Cheng X,Zhou X,Song S,Wu M,Baolatejiang R,Lu Y,Li Y,Zhang W,Lv W,Ye Y,Zhou Q,Wang H,Zhang J,Xing Q,Tang B

更新日期：2017-04-10 00:00:00

abstract：:The AB0 blood group has been linked to ischaemic heart disease, stroke, and periodontal disease, while the Lewis blood group has been linked to ischaemic heart disease and obesity, all of which have been associated with periodontitis. AB0 or Lewis blood group phenotype may therefore constitute common hereditary compon...

journal_title：Scientific reports

authors： Enevold C,Nielsen CH,Molbo D,Lund R,Bendtzen K,Fiehn N-,Holmstrup P

更新日期：2019-04-18 00:00:00

abstract：:Dogs' attachment towards humans might be the core of their social skillset, yet the origins of their ability to build such a bond are still unclear. Here we show that adult, hand-reared wolves, similarly to dogs, form individualized relationship with their handler. During separation from their handler, wolves, much li...

journal_title：Scientific reports

authors： Lenkei R,Újváry D,Bakos V,Faragó T

更新日期：2020-10-14 00:00:00

abstract：:Salt crystallization is a major cause of weathering of rocks, artworks and monuments. Damage can only occur if crystals continue to grow in confinement, i.e. within the pore space of these materials, thus generating mechanical stress. We report the direct measurement, at the microscale, of the force exerted by growing...

journal_title：Scientific reports

authors： Desarnaud J,Bonn D,Shahidzadeh N

更新日期：2016-08-05 00:00:00

abstract：:Understanding ethanol-induced stresses and responses in biofuel-producing bacteria at systems level has significant implications in engineering more efficient biofuel producers. We present a computational study of transcriptomic and genomic data of both ethanol-stressed and ethanol-adapted E. coli cells with computati...

journal_title：Scientific reports

authors： Cao H,Wei D,Yang Y,Shang Y,Li G,Zhou Y,Ma Q,Xu Y

更新日期：2017-03-16 00:00:00

abstract：:Accurate measurements of autonomic nerve regulation in heart failure (HF) were unresolved. The discriminating performance of deceleration and acceleration capacities of heart rate in HF was evaluated in 130 HF patients and 212 controls. Acceleration capacity and deceleration capacity were independent risk factors for ...

journal_title：Scientific reports

authors： Hu W,Jin X,Zhang P,Yu Q,Yin G,Lu Y,Xiao H,Chen Y,Zhang D

更新日期：2016-03-23 00:00:00

abstract：:Organic light emitting diodes (OLEDs) operating in the near-infrared spectral region are gaining growing relevance for emerging photonic technologies, such as lab-on-chip platforms for medical diagnostics, flexible self-medicated pads for photodynamic therapy, night vision and plastic-based telecommunications. The ach...

journal_title：Scientific reports

authors： Sassi M,Buccheri N,Rooney M,Botta C,Bruni F,Giovanella U,Brovelli S,Beverina L

更新日期：2016-09-28 00:00:00

abstract：:Induction chemotherapy treatment for nasopharyngeal carcinoma (NPC) is controversial. The aim of this study was to evaluate the treatment outcomes and toxicities between two induction chemotherapy regimens, with both followed by concurrent chemoradiotherapy. The first strategy used docetaxel, cisplatin and fluorouraci...

journal_title：Scientific reports

authors： Zeng Z,Yan RN,Tu L,Wang YY,Chen PR,Luo F,Liu L

更新日期：2018-10-22 00:00:00

abstract：:Intracellular calcium ([Ca2+]i) signaling is an essential universal secondary messenger in articular chondrocytes. However, little is known about its spatiotemporal features in the context of osteoarthritis (OA). Herein, by examining the cartilage samples collected from patients undergoing knee arthroscopic surgery, w...

journal_title：Scientific reports

authors： Gong X,Xie W,Wang B,Gu L,Wang F,Ren X,Chen C,Yang L

更新日期：2017-12-06 00:00:00

abstract：:Tumour growth and metastatic colonization is strongly influenced by the tumour stroma, including cancer-associated fibroblasts (CAF). Multipotent mesenchymal stromal cells (MSC) are a possible source of CAF following myofibroblastic differentiation, and we have previously shown that MSC support tumour growth. Triggere...

journal_title：Scientific reports

authors： Werner S,Lützkendorf J,Müller T,Müller LP,Posern G

更新日期：2019-08-13 00:00:00

abstract：:The genome of influenza A virus (IAV) comprises eight RNA segments (vRNA) which are transcribed and replicated by the heterotrimeric IAV RNA-dependent RNA-polymerase (RdRp). RdRp consists of three subunits (PA, PB1 and PB2) and binds both the highly conserved 3'- and 5'-ends of the vRNA segment. The IAV RdRp is an imp...

journal_title：Scientific reports

authors： Swale C,Monod A,Tengo L,Labaronne A,Garzoni F,Bourhis JM,Cusack S,Schoehn G,Berger I,Ruigrok RW,Crépin T

更新日期：2016-04-20 00:00:00

abstract：:In this study, we prepared, characterized, and performed toxicity analyses of poly(ε-caprolactone) nanocapsules loaded with neem oil. Three formulations were prepared by the emulsion/solvent evaporation method. The nanocapsules showed a mean size distribution around 400 nm, with polydispersity below 0.2 and were stabl...

journal_title：Scientific reports

authors： Pasquoto-Stigliani T,Campos EVR,Oliveira JL,Silva CMG,Bilesky-José N,Guilger M,Troost J,Oliveira HC,Stolf-Moreira R,Fraceto LF,de Lima R

更新日期：2017-07-19 00:00:00

abstract：:Mendelian randomisation studies from Asia suggest detrimental influences of alcohol on cardiovascular risk factors, but such associations are observed mainly in men. The absence of associations of genetic variants (e.g. rs671 in ALDH2) with such risk factors in women - who drank little in these populations - provides ...

journal_title：Scientific reports

authors： Cho Y,Shin SY,Won S,Relton CL,Davey Smith G,Shin MJ

更新日期：2015-12-21 00:00:00

abstract：:Brood is a very valuable part of an ant colony and behaviours increasing its number with minimum investment is expected to be favoured by natural selection. Brood theft has been well documented in ants belonging to the subfamilies Myrmicinae and Formicinae. In this study we report opportunistic brood theft in the cont...

journal_title：Scientific reports

authors： Paul B,Paul M,Annagiri S

更新日期：2016-10-31 00:00:00

abstract：:The combined effects of cervical electrical stimulation alone or in combination with the monoaminergic agonist buspirone on upper limb motor function were determined in six subjects with motor complete (AIS B) injury at C5 or above and more than one year from time of injury. Voluntary upper limb function was evaluated...

journal_title：Scientific reports

authors： Freyvert Y,Yong NA,Morikawa E,Zdunowski S,Sarino ME,Gerasimenko Y,Edgerton VR,Lu DC

更新日期：2018-10-19 00:00:00