A comparative study of evaluating missing value imputation methods in label-free proteomics.

abstract：:Deriving a 3D structural representation of an object from its 2D input is one of the great challenges for the visual system and yet, this type of representation is critical for the successful recognition of and interaction with objects. Perhaps reflecting the importance of this computation, infants have some sensitivi...

journal_title：Scientific reports

authors： Freud E,Behrmann M

更新日期：2017-09-08 00:00:00

abstract：:The current study aims to evaluate the burden of disease in Singapore by estimating the quality-adjusted life years (QALYs) lost due to mental disorders and chronic physical conditions. The second Singapore Mental Health Study (SMHS-2016) was conducted in 2016 among 6126 respondents aged 18 years and above. The World ...

journal_title：Scientific reports

authors： Abdin E,Chong SA,Vaingankar JA,Shafie S,Verma S,Luo N,Tan KB,James L,Heng D,Subramaniam M

更新日期：2020-02-14 00:00:00

abstract：:Cover cropping is proposed to enhance soil microbial diversity and activity, with cover crop type affecting microbial groups in different ways. We compared fungal community compositions of bulk soils differing by cover crop treatment, season, and edaphic properties in the third year of an organic, conventionally tille...

journal_title：Scientific reports

authors： Cloutier ML,Murrell E,Barbercheck M,Kaye J,Finney D,García-González I,Bruns MA

更新日期：2020-04-10 00:00:00

abstract：:Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V). Several lines of evidence suggest that tanycytes may be involved in the regulation of energy homeostasis...

journal_title：Scientific reports

authors： Uranga RM,Millán C,Barahona MJ,Recabal A,Salgado M,Martinez F,Ordenes P,Elizondo-Vega R,Sepúlveda F,Uribe E,García-Robles MLÁ

更新日期：2017-06-16 00:00:00

abstract：:Antimicrobial peptides, produced by innate immune system of hosts in response to invading pathogens, are capable of fighting against a spectrum of bacteria, viruses, fungi, parasites and cancer cells. Here, a recombinant silkworm AMP Bmattacin2 from heterologous expression is studied, indicating a broad spectrum of an...

journal_title：Scientific reports

authors： Li Z,Liu X,Li Y,Lan X,Leung PH,Li J,Li G,Xie M,Han Y,Lin X

更新日期：2016-08-09 00:00:00

abstract：:Tolerance to Dutch elm disease (DED) has been linked to the rapid and/or high induction of disease-responsive genes after infection with the fungus Ophiostoma novo-ulmi. Although the fungal infection by O. novo-ulmi primarily takes places in xylem vessels, it is still unclear how xylem contributes to the defense again...

journal_title：Scientific reports

authors： Sherif SM,Erland LA,Shukla MR,Saxena PK

更新日期：2017-08-02 00:00:00

abstract：:The nonsynonymous SCN10A single nucleotide polymorphism (SNP) rs6795970 has been reported to associate with PR interval and atrial fibrillation (AF) and in strong linkage disequilibrium (LD) with the AF-associated SNP rs6800541. In this study, we investigated whether rs6795970 polymorphisms are associated with AF recu...

journal_title：Scientific reports

authors： Wu H,Xu J,Chen S,Zhou G,Qi B,Wei Y,Hu E,Tang D,Chen G,Li H,Zhao L,Shi Y,Liu S

更新日期：2017-03-10 00:00:00

abstract：:Nucleic acid polymers (NAPs) block the release of subviral particles from hepatocytes, a mechanism consistent with their antiviral activity against hepatitis B virus (HBV) in patients. Analysis of immunostimulatory properties of NAPs were conducted with several NAP species: REP 2006, the prototypic degenerate NAP [dN]...

journal_title：Scientific reports

authors： Real CI,Werner M,Paul A,Gerken G,Schlaak JF,Vaillant A,Broering R

更新日期：2017-03-08 00:00:00

abstract：:Infrared detection devices are becoming miniature with micro or nano-scale size. The advantages of downsizing come on the expense of insufficient collection of infrared radiation. Therefore, utilizing nano-plasmonic optical antennas becomes mandatory. However, it is desirable to develop antennas with broad bandwidth, ...

journal_title：Scientific reports

authors： Awad E

更新日期：2019-08-21 00:00:00

abstract：:CD4(+)CD25(+) T cells are critical for maintenance of immunologic self-tolerance. We measured the number of CD4(+)CD25(+) cells in the patients with primary malignant hypertension related kidney injury, to explore the molecular pathogenesis of this disease. We selected 30 patients with primary malignant hypertension r...

journal_title：Scientific reports

authors： Huang H,Luo Y,Liang Y,Long X,Peng Y,Liu Z,Wen X,Jia M,Tian R,Bai C,Li C,He F,Lin Q,Wang X,Dong X

更新日期：2016-06-09 00:00:00

abstract：:Given that observational associations may be inaccurate, we used offspring blood pressure (BP) to provide alternative estimates of the associations between own BP and mortality. Observational associations between BP and mortality, estimated as hazard ratios (HRs) from Cox regression, were compared to HRs obtained usin...

journal_title：Scientific reports

authors： Wade KH,Carslake D,Nilsen TI,Timpson NJ,Davey Smith G,Romundstad P

更新日期：2015-07-22 00:00:00

abstract：:In this study we used the Illumina Infinium Methylation array to investigate in a cohort of matched archival human tissue samples (n = 32) from 14 individuals with soft tissue sarcomas if genome-wide methylation changes occur during metastatic and recurrent (Met/Rec) disease. A range of sarcoma types were selected for...

journal_title：Scientific reports

authors： Vargas AC,Gray LA,White CL,Maclean FM,Grimison P,Ardakani NM,Bonar F,Algar EM,Cheah AL,Russell P,Mahar A,Gill AJ

更新日期：2021-01-12 00:00:00

abstract：:Humans have an innate set of emotions recognised universally. However, emotion recognition also depends on socio-cultural rules. Although adults recognise vocal emotions universally, they identify emotions more accurately in their native language. We examined developmental trajectories of universal vocal emotion recog...

journal_title：Scientific reports

authors： Chronaki G,Wigelsworth M,Pell MD,Kotz SA

更新日期：2018-06-14 00:00:00

abstract：:Chronic myeloid leukemia (CML) is characterized in the majority of cases by a t(9;22)(q34;q11) translocation, also called the Philadelphia chromosome, giving rise to the BCR-ABL1 fusion protein. Current treatment with tyrosine kinase inhibitors is directed against the constitutively active ABL1 domain of the fusion pr...

journal_title：Scientific reports

authors： Löf L,Arngården L,Olsson-Strömberg U,Siart B,Jansson M,Dahlin JS,Thörn I,Christiansson L,Hermansson M,Larsson A,Ahlstrand E,Wålinder G,Söderberg O,Rosenquist R,Landegren U,Kamali-Moghaddam M

更新日期：2017-04-04 00:00:00

abstract：:Procalcitonin (PCT) is a useful marker for the diagnosis of systemic inflammatory response syndrome. In addition, PCT is affected by renal function. However, few studies have investigated the relationship between PCT and the development of acute kidney injury (AKI). Hence, we investigated whether serum PCT levels at t...

journal_title：Scientific reports

authors： Chun K,Chung W,Kim AJ,Kim H,Ro H,Chang JH,Lee HH,Jung JY

更新日期：2019-03-18 00:00:00

abstract：:Living organisms have to adjust to their surrounding in order to survive in stressful conditions. We study this mechanism in one of most primitive creatures - photosynthetic green sulfur bacteria. These bacteria absorb photons very efficiently using the chlorosome antenna complexes and perform photosynthesis in extrem...

journal_title：Scientific reports

authors： Saikin SK,Khin Y,Huh J,Hannout M,Wang Y,Zare F,Aspuru-Guzik A,Tang JK

更新日期：2014-05-27 00:00:00

abstract：:Tau is a microtubule-associated protein whose C-terminal domain consisting of four repeat regions R1, R2, R3 and R4 binds to microtubules to stabilize them. In several neurodegenerative diseases, tau detaches from microtubules to form insoluble aggregates leading to tauopathy. Microtubules are made up of αβ tubulin su...

journal_title：Scientific reports

authors： Bhandare VV,Kumbhar BV,Kunwar A

更新日期：2019-07-25 00:00:00

abstract：:Arabidopsis thaliana contains the putative K+ efflux transporters KEA1-KEA6, similar to KefB and KefC of Escherichia coli. KEA1-KEA3 are involved in the regulation of photosynthetic electron transport and chloroplast development. KEA4-KEA6 mediate pH regulation of the endomembrane network during salinity stress. Howev...

journal_title：Scientific reports

authors： Tsujii M,Kera K,Hamamoto S,Kuromori T,Shikanai T,Uozumi N

更新日期：2019-07-11 00:00:00

abstract：:Age-related macular degeneration (AMD) is a chronic degenerative disease of the retina. Recent reports have highlighted the potential role of mucosal surface microbes in the pathogenesis of AMD. In this case-control study, the composition of the nasal and oral microbiota in newly diagnosed neovascular age-related macu...

journal_title：Scientific reports

authors： Rullo J,Far PM,Quinn M,Sharma N,Bae S,Irrcher I,Sharma S

更新日期：2020-03-02 00:00:00

abstract：:The iron binding capacities (IBC) of fulvic acid (FA) and humic acid (HA) were determined in the salinity range from 5 to 40. The results indicated that IBC decreased while salinity increased. In addition, dissolved iron (dFe), FA and HA were also determined along the Yangtze River estuary's increasing salinity gradie...

journal_title：Scientific reports

authors： Yang R,Su H,Qu S,Wang X

更新日期：2017-05-03 00:00:00

abstract：:Maoto, a traditional Japanese Kampo medicine, has been used to treat various respiratory diseases, including respiratory infections and influenza. Ephedrine (EPD), the main ingredient in maoto, is also clinically used to treat respiratory diseases. However, the pharmacokinetics and distribution of EPD in the lungs aft...

journal_title：Scientific reports

authors： Matsumoto T,Kushida H,Matsushita S,Oyama Y,Suda T,Watanabe J,Kase Y,Setou M

更新日期：2017-03-08 00:00:00

abstract：:αβ T cells respond to peptide epitopes presented by major histocompatibility complex (MHC) molecules. The role of T cell receptor (TCR) germline complementarity determining regions (CDR1 and 2) in MHC restriction is not well understood. Here, we examine T cell development, MHC restriction and antigen recognition where...

journal_title：Scientific reports

authors： Attaf M,Holland SJ,Bartok I,Dyson J

更新日期：2016-10-24 00:00:00

abstract：:Glaucoma is a leading cause of irreversible vision loss predicted to affect more than 100 million people by 2040. Intraocular pressure (IOP) reduction prevents development of glaucoma and vision loss from glaucoma. Glaucoma surgeries reduce IOP by facilitating aqueous humor outflow through a vent fashioned from the wa...

journal_title：Scientific reports

authors： Parikh KS,Josyula A,Omiadze R,Ahn JY,Ha Y,Ensign LM,Hanes J,Pitha I

更新日期：2020-07-31 00:00:00

abstract：:Congenital ptosis may be associated with abnormalities of visual development and function, including amblyopia, strabismus and refractive errors. However, the prevalence estimates of these abnormalities vary widely. We performed a systematic review and meta-analysis to estimate the prevalence of amblyopia, strabismus ...

journal_title：Scientific reports

authors： Wang Y,Xu Y,Liu X,Lou L,Ye J

更新日期：2018-05-29 00:00:00

abstract：:The role of Toll-like receptor-2 (TLR2) in radio-resistance remained largely unknown. TLR2 knockout (TLR2(-/-)) mice received radiation of 6.5 Gy, and then were studied. We found that radiation resulted in more severe mortality and morbidity rates in TLR2(-/-) mice. The cause of death in TLR2(-/-) mice may be severe a...

journal_title：Scientific reports

authors： Gao F,Zhang C,Zhou C,Sun W,Liu X,Zhang P,Han J,Xian L,Bai D,Liu H,Cheng Y,Li B,Cui J,Cai J,Liu C

更新日期：2015-08-13 00:00:00

abstract：:CRISPR/Cas9-mediated genome editing is a next-generation strategy for genetic modifications. Typically, sgRNA is constitutively expressed relying on RNA polymerase III promoters. Polymerase II promoters initiate transcription in a flexible manner, but sgRNAs generated by RNA polymerase II promoter lost their nuclease ...

journal_title：Scientific reports

authors： Xie C,Chen YL,Wang DF,Wang YL,Zhang TP,Li H,Liang F,Zhao Y,Zhang GY

更新日期：2017-07-19 00:00:00

abstract：:The aim of the present study was to evaluate the healthy lifestyle behaviors in hypertensive patients (aware, n = 1364 and not aware, n = 1213) based on 2011 national survey of risk factors of non-communicable disease (SuRFNCD) of Iran. Lifestyle score was calculated based on lifestyle behaviors, including smoking sta...

journal_title：Scientific reports

authors： Akbarpour S,Khalili D,Zeraati H,Mansournia MA,Ramezankhani A,Fotouhi A

更新日期：2018-05-31 00:00:00

abstract：:Diabetes is expected to accelerate age-related ganglion cell-inner plexiform layer (GC-IPL) loss, but there is limited information on the rate of reduction in GC-IPL thicknesses. We aimed to evaluate the reduction rate of GC-IPL thickness in diabetic patients, and to compare the rates between patients without and with...

journal_title：Scientific reports

authors： Lim HB,Shin YI,Lee MW,Koo H,Lee WH,Kim JY

更新日期：2020-01-30 00:00:00

abstract：:Staphylococcus aureus strains carrying enterotoxin A gene (sea) causes food poisoning and cannot be distinguished from non-pathogenic strains by the culture method. Here, we developed a rapid, specific and sensitive visual detection of sea using loop-mediated isothermal amplification (LAMP) combined with nanogold prob...

journal_title：Scientific reports

authors： Srimongkol G,Ditmangklo B,Choopara I,Thaniyavarn J,Dean D,Kokpol S,Vilaivan T,Somboonna N

更新日期：2020-05-08 00:00:00

abstract：:Secondary bacterial infections increase morbidity and mortality of influenza A virus (IAV) infections. Bacteria are able to invade due to virus-induced depletion of alveolar macrophages (AMs), but this is not the only contributing factor. By analyzing a kinetic model, we uncovered a nonlinear initial dose threshold th...

journal_title：Scientific reports

authors： Smith AM,Smith AP

更新日期：2016-12-15 00:00:00