Airfoil leading edge blowing to control bow shock waves.

abstract：:Genome-wide studies on high-altitude adaptation have received increased attention as a classical case of organismal evolution under extreme environment. However, the current genetic understanding of high-altitude adaptation emanated mainly from autosomal analyses. Only a few earlier genomic studies paid attention to t...

journal_title：Scientific reports

authors： Wu H,Liu YH,Wang GD,Yang CT,Otecko NO,Liu F,Wu SF,Wang L,Yu L,Zhang YP

更新日期：2016-10-07 00:00:00

abstract：:Delta-9-tetrahydrocannabinol (THC) is the primary psychoactive compound in Cannabis, which is studied extensively for its medicinal value. A central gap in the science is the underlying mechanisms surrounding THC's therapeutic effects and the role of gut metabolite profiles. Using a mass-spectrometry based metabolomic...

journal_title：Scientific reports

authors： Oza M,Becker W,Gummadidala PM,Dias T,Omebeyinje MH,Chen L,Mitra C,Jesmin R,Chakraborty P,Sajish M,Hofseth LJ,Banerjee K,Wang Q,Moeller PDR,Nagarkatti M,Nagarkatti P,Chanda A

更新日期：2019-07-19 00:00:00

abstract：:Abiotic stress significantly impacts growth and yield of crop plants. It is imperative for crop improvement to discover and utilize stress-tolerant functional genes. In this study, genes responding to abiotic stresses, such as freezing, salt and osmotic stress, were screened from a cDNA yeast library that was construc...

journal_title：Scientific reports

authors： Wang J,Mao X,Wang R,Li A,Zhao G,Zhao J,Jing R

更新日期：2019-01-15 00:00:00

abstract：:Numerical aberration of the centrosome results in chromosome missegregation, eventually leading to chromosomal instability, a hallmark of human tumor malignancy. Large tumor suppressors 1 and 2 (Lats1 and Lats2) are central kinases in the Hippo pathway and regulate development and tumorigenesis by coordinating the bal...

journal_title：Scientific reports

authors： Mukai S,Yabuta N,Yoshida K,Okamoto A,Miura D,Furuta Y,Abe T,Nojima H

更新日期：2015-11-04 00:00:00

abstract：:Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutations of SHP-2 have been foun...

journal_title：Scientific reports

authors： Shim SY,Jeong HJ,Park HJ,Kwon EY,Kim BM,Choi YJ,Choi YH,Cho SJ,Choi JH,Park EA

更新日期：2017-07-20 00:00:00

abstract：:The goal of this work was to develop a mathematical model to predict Kaplan-Meier survival curves for chemotherapy combined with radiation in Non-Small Cell Lung Cancer patients for use in clinical trial design. The Gompertz model was used to describe tumor growth, radiation effect was simulated by the linear-quadrati...

journal_title：Scientific reports

authors： Geng C,Paganetti H,Grassberger C

更新日期：2017-10-19 00:00:00

abstract：:Quantitative reverse transcription PCR (RT-qPCR) is one of the most efficient, reliable and widely used techniques to quantify gene expression. In this study, we evaluated the performance of six southern corn rootworm, Diabrotica undecimpunctata howardi (Barber), housekeeping genes (HKG), β-actin (Actin), β-tubulin (T...

journal_title：Scientific reports

authors： Basu S,Pereira AE,Pinheiro DH,Wang H,Valencia-Jiménez A,Siegfried BD,Louis J,Zhou X',Vélez AM

更新日期：2019-07-24 00:00:00

abstract：:Understanding the phylogeography and genetic structure of populations and the processes responsible of patterns therein is crucial for evaluating the vulnerability of marine species and developing management strategies. In this study, we explore how past climatic events and ongoing oceanographic and demographic proces...

journal_title：Scientific reports

authors： Garcia-Cisneros A,Palacín C,Ben Khadra Y,Pérez-Portela R

更新日期：2016-09-15 00:00:00

abstract：:Mitochondrial activity is central to tissue homeostasis. Mitochondria dysfunction constitutes a hallmark of many genetic diseases and plays a key role in tumor progression. The essential role of mitochondria, added to their recently documented capacity to transfer from cell to cell, obviously contributes to their curr...

journal_title：Scientific reports

authors： Caicedo A,Fritz V,Brondello JM,Ayala M,Dennemont I,Abdellaoui N,de Fraipont F,Moisan A,Prouteau CA,Boukhaddaoui H,Jorgensen C,Vignais ML

更新日期：2015-03-13 00:00:00

abstract：:The moist savanna zone covers 0.5 × 106 km2 in West Africa and is characterized by very low soil N levels limiting primary production, but the ecology of nitrifiers in these (agro)ecosystems is largely unknown. We compared the effects of six agricultural practices on nitrifier activity, abundance and diversity at nine...

journal_title：Scientific reports

authors： Assémien FL,Pommier T,Gonnety JT,Gervaix J,Le Roux X

更新日期：2017-08-31 00:00:00

abstract：:Continuous solidification experiments were carried out with Cu-Bi-Sn alloys under the effects of Electric Current Pulses (ECPs). A model describing the microstructure evolution was developed. The formation of the microstructure in the continuously solidified alloys was calculated. The calculations demonstrated that EC...

journal_title：Scientific reports

authors： Hongxiang J,Jie H,Jiuzhou Z

更新日期：2015-07-31 00:00:00

abstract：:C. canimorsus and C. cynodegmi are dog and cat commensals which can be transmitted to humans via bites or scratches and can cause sepsis, meningitis, endocarditis, and eye- or wound infections. Recently an additional Capnocytophaga species was identified as part of the oral flora of healthy dogs and was given the name...

journal_title：Scientific reports

authors： Zangenah S,Abbasi N,Andersson AF,Bergman P

更新日期：2016-03-07 00:00:00

abstract：:Bone regeneration, following fracture, relies on autologous and allogenic bone grafts. However, majority of fracture population consists of older individuals with poor quality bone associated with loss and/or modification of matrix proteins critical for bone formation and mineralization. Allografts suffer from same li...

journal_title：Scientific reports

authors： Carvalho MS,Poundarik AA,Cabral JMS,da Silva CL,Vashishth D

更新日期：2018-09-26 00:00:00

abstract：:PAP80-2a, purified from Pholiota adiposa mycelia, is a polysaccharide exhibiting prominent antitumor effects. However, the yield of PAP80-2a was low and its structure has not been characterized, impeding the exploration of its structure-function relationship, thus influencing the development of oral drugs for antitumo...

journal_title：Scientific reports

authors： Zou Y,Du F,Hu Q,Wang H

更新日期：2019-02-11 00:00:00

abstract：:Psychopathic traits of conduct disorder (CD) have a core callous-unemotional (CU) component and an impulsive-antisocial component. Previous task-driven fMRI studies have suggested that psychopathic traits are associated with dysfunction of several brain areas involved in different cognitive functions (e.g., empathy, r...

journal_title：Scientific reports

authors： Pu W,Luo Q,Jiang Y,Gao Y,Ming Q,Yao S

更新日期：2017-09-12 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Song H,Gao H,Liu J,Tian P,Nan Z

更新日期：2020-02-27 00:00:00

abstract：:This prospective randomized double-masked study investigated the effects of 20 mg lutein supplementation with two different capsules (beeswax or glycerol fatty acid esters) for 6 months on the fellow eyes of 39 Japanese patients with unilateral age-related macular degeneration, and assessed the factors associated with...

journal_title：Scientific reports

authors： Sawa M,Shunto T,Nishiyama I,Yokoyama A,Shigeta R,Miura S,Kawasaki R

更新日期：2020-04-06 00:00:00

abstract：:A theoretical investigation of the unique electronic transport properties of the junctions composed of boron nitride atomic chains bridging symmetric graphene electrodes with point-contacts is executed through non-equilibrium Green's function technique in combination with density functional theory. Compared with carbo...

journal_title：Scientific reports

authors： Xu X,Li W,Liu L,Feng J,Jiang Y,Tian WQ

更新日期：2016-05-23 00:00:00

abstract：:Microbiology of a hypersaline oil reservoir located in Central Africa was investigated with molecular and culture methods applied to preserved core samples. Here we show that the community structure was partially acquired during sedimentation, as many prokaryotic 16S rRNA gene sequences retrieved from the extracted DN...

journal_title：Scientific reports

authors： Gales G,Tsesmetzis N,Neria I,Alazard D,Coulon S,Lomans BP,Morin D,Ollivier B,Borgomano J,Joulian C

更新日期：2016-03-11 00:00:00

abstract：:Spotted seal (Phoca largha) is a critically endangered pinniped in China and South Korea. The conventional method to protect and maintain the P. largha population is to keep them captive in artificially controlled environments. However, little is known about the physiological differences between wild and captive P. la...

journal_title：Scientific reports

authors： Tian J,Du J,Han J,Bao X,Song X,Lu Z

更新日期：2020-10-30 00:00:00

abstract：:High efficiency polymer:fullerene photovoltaic device layers self-assemble with hierarchical features from ångströms to 100's of nanometers. The feature size, shape, composition, orientation, and order all contribute to device efficiency and are simultaneously difficult to study due to poor contrast between carbon bas...

journal_title：Scientific reports

authors： Roehling JD,Baran D,Sit J,Kassar T,Ameri T,Unruh T,Brabec CJ,Moulé AJ

更新日期：2016-08-08 00:00:00

abstract：:ABO blood group is associated with cardiovascular disease, with significantly lower risk in blood group O individuals. ABO(H) blood group determinants are expressed on different glycoproteins on platelet surfaces. In addition, ABO(H) structures are also present on VWF glycans. These ABO(H) carbohydrates influence both...

journal_title：Scientific reports

authors： O'Donghaile D,Jenkins PV,McGrath RT,Preston L,Field SP,Ward SE,O'Sullivan JM,O'Donnell JS

更新日期：2020-10-27 00:00:00

abstract：:Four plant tumorigenic strains 932, 1019, 1078T and 1081 isolated from cane gall tumors on thornless blackberry (Rubus sp.) were characterized. They shared low sequence identity with related Rhizobium spp. based on comparisons of 16S rRNA gene (≤98%) and housekeeping genes atpD, recA and rpoB (<90%). Phylogenetic anal...

journal_title：Scientific reports

authors： Kuzmanović N,Smalla K,Gronow S,Puławska J

更新日期：2018-06-13 00:00:00

abstract：:Ubiquitylation is a protein modification implicated in several cellular processes. This process is reversible by the action of deubiquinating enzymes (DUBs). USP45 is a ubiquitin specific protease about which little is known, aside from roles in DNA damage repair and differentiation of the vertebrate retina. Here, by ...

journal_title：Scientific reports

authors： Conte C,Griffis ER,Hickson I,Perez-Oliva AB

更新日期：2018-09-26 00:00:00

abstract：:Cisplatin (CDDP) is potent anticancer agent used for several tumor types. Thymoquinone (TQ) is naturally occurring compound drawing great attention as anticancer and chemomodulator for chemotherapies. Herein, we studied the potential cytotoxicity of thymoquinone, CDDP and their combination against human oral squamous ...

journal_title：Scientific reports

authors： Alaufi OM,Noorwali A,Zahran F,Al-Abd AM,Al-Attas S

更新日期：2017-10-13 00:00:00

abstract：:Gold is a noble metal typically stable as a solid in a face-centered cubic (FCC) structure under ambient conditions; however, under particular circumstances aberrant allotropes have been synthesized. In this work, we document the phase transformation of 25 nm thick nanocrystalline (NC) free-standing gold thin-film via...

journal_title：Scientific reports

authors： Suri PK,Nathaniel JE 2nd,Li N,Baldwin JK,Wang Y,Hattar K,Taheri ML

更新日期：2020-10-20 00:00:00

abstract：:Staphylococcus aureus colonizes the skin of atopic dermatitis (AD) individuals, but the impact of its enterotoxins on the chronic activation of CD4+ T cells demands further analysis. We aimed to analyze the CD4+ T cell anergy profile and their phenotypic and functional features through differential expression of cellu...

journal_title：Scientific reports

authors： Orfali RL,Yoshikawa FSY,Oliveira LMDS,Pereira NZ,de Lima JF,Ramos YÁL,Duarte AJDS,Sato MN,Aoki V

更新日期：2019-09-11 00:00:00

abstract：:Human mesenchymal stromal cells (MSCs) have served as a major cellular resource for cell-based immunomodulatory and regenerative therapies. However, genomic instability may accumulate during ex vivo expansion of MSCs, thereby increasing the potential of malignant transformation. Here, we performed whole genome sequenc...

journal_title：Scientific reports

authors： Kim M,Rhee JK,Choi H,Kwon A,Kim J,Lee GD,Jekarl DW,Lee S,Kim Y,Kim TM

更新日期：2017-11-06 00:00:00

abstract：:The exact extent, by which the hydrologic cycle in the Neotropics was affected by external forcing during the last deglaciation, remains poorly understood. Here we present a new paleo-rainfall reconstruction based on high-resolution speleothem δ18O records from the core region of the South American Monsoon System (SAM...

journal_title：Scientific reports

authors： Novello VF,Cruz FW,Vuille M,Stríkis NM,Edwards RL,Cheng H,Emerick S,de Paula MS,Li X,Barreto ES,Karmann I,Santos RV

更新日期：2017-03-10 00:00:00

abstract：:It is urgent to find an optimised therapy regimen for the control of MDR-TB globally. This study aimed to evaluate the efficiacy and safety of a combined regimen of rhIL-2 injection and standard chemotherapy within 18-month duration in a randomized controlled trial conducted in 14 centres in eastern China. From Jan. 2...

journal_title：Scientific reports

authors： Tan Q,Min R,Dai GQ,Wang YL,Nan L,Yang Z,Xia J,Pan SY,Mao H,Xie WP,Wang H

更新日期：2017-12-19 00:00:00