Abstract:
:Seed size/weight is a major agronomic trait which determine crop productivity in legumes. To understand the genetic basis of seed size determination, we sought to identify DNA polymorphisms between two small (Himchana 1 and Pusa 362) and two large-seeded (JGK 3 and PG 0515) chickpea cultivars via whole genome resequencing. We identified a total of 75535 single nucleotide polymorphisms (SNPs), 6486 insertions and deletions (InDels), 1938 multi-nucleotide polymorphisms (MNPs) and 5025 complex variants between the two small and two large-seeded chickpea cultivars. Our analysis revealed 814, 244 and 72 seed-specific genes harboring DNA polymorphisms in promoter or non-synonymous and large-effect DNA polymorphisms, respectively. Gene ontology analysis revealed enrichment of cell growth and division related terms in these genes. Among them, at least 22 genes associated with quantitative trait loci, and those involved in cell growth and division and encoding transcription factors harbored promoter and/or large-effect/non-synonymous DNA polymorphisms. These also showed higher expression at late-embryogenesis and/or mid-maturation stages of seed development in the large-seeded cultivar, suggesting their role in seed size/weight determination in chickpea. Altogether, this study provided a valuable resource for large-scale genotyping applications and a few putative candidate genes that might play crucial role in governing seed size/weight in chickpea.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Rajkumar MS,Garg R,Jain Mdoi
10.1038/s41598-018-35140-wsubject
Has Abstractpub_date
2018-11-14 00:00:00pages
16795issue
1issn
2045-2322pii
10.1038/s41598-018-35140-wjournal_volume
8pub_type
杂志文章abstract::This observational study investigated the impact of hyponatremia resolution on the results of a comprehensive geriatric assessment (CGA) in 150 patients with age ≥70 years and serum sodium <130 mEq/L. The test battery including Barthel index of Activities of Daily Living (ADL) and various tests of neurocognitive funct...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49054-8
更新日期:2019-08-29 00:00:00
abstract::In this study, an interval optimization model is developed to maximize the benefits of a water rights transfer system that comprises industry and agriculture sectors in the Ningxia Hui Autonomous Region in China. The model is subjected to a number of constraints including water saving potential from agriculture and ec...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02734-9
更新日期:2017-06-14 00:00:00
abstract::We here describe the dc magnetic field over the human head produced by healthy hair follicles when the scalp is lightly pressed. This phenomenon was briefly reported decades earlier, where a double-planar SQUID (Superconducting Quantum Interference Devices) gradiometer at a single location was used. We here perform a ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52110-y
更新日期:2019-10-30 00:00:00
abstract::Inflammation is considered as a major contributor to brain injury following cerebral ischemia. The therapeutic potential of both MLC601/MLC901, which are herbal extract preparations derived from Chinese Medicine, has been reported both in advanced stroke clinical trials and also in animal and cellular models. The aim ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36138-0
更新日期:2018-12-24 00:00:00
abstract::The profiles of time-contrast (TC) -curves from popular MRI injectors derived at the injection site of the attached tube-line system were compared. Variations of TC-profiles were previously reported to potentially influence image quality in time critical MRI measurements. TC-curves from five injectors obtained during ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76536-x
更新日期:2020-11-11 00:00:00
abstract::We here develop a three-dimensional DMF (3D DMF) platform with patterned electrodes submerged in an oil medium to provide fundamental solutions to the technical limitations of 2D DMF platforms and water-air systems. 3D droplet manipulation on patterned electrodes is demonstrated by programmably controlling electrical ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10685
更新日期:2015-06-02 00:00:00
abstract::We investigated the metabolic outcome of different coping strategies in 129S6/SvEvTac (129Sv) and C57BL/6Ntac (Bl6) strains. Two different batches of male 129Sv and Bl6 mice were used. One batch was not subjected to any behavioral manipulations (home cage control; HCC), whereas the other batch was treated with saline ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21752-9
更新日期:2018-02-21 00:00:00
abstract::Pediococcus pentosaceus LBM 18 has shown potential as producer of an antibacterial and antifungal bacteriocin-like inhibitory substance (BLIS). BLIS inhibited the growth of spoilage bacteria belonging to Lactobacillus, Enterococcus and Listeria genera with higher activity than Nisaplin used as control. It gave rise to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68922-2
更新日期:2020-07-23 00:00:00
abstract::This study utilized a Förster resonance energy transfer (FRET)-based molecular tension sensor and live cell imaging to evaluate the effect of osteocytes, a mechanosensitive bone cell, on the migratory behavior of tumor cells. Two cell lines derived from MDA-MB-231 breast cancer cells were transfected with the vinculin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42132-x
更新日期:2019-04-04 00:00:00
abstract::The intravenous, intramuscular or intraperitoneal administration of water solubilized graphene nanoparticles for biomedical applications will result in their interaction with the hematological components and vasculature. Herein, we have investigated the effects of dextran functionalized graphene nanoplatelets (GNP-Dex...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02584
更新日期:2013-01-01 00:00:00
abstract::Cues previously paired with rewarding stimuli induce a time-dependent increase in the motivational craving state (incubation of craving). Whether there is an increase in craving for high-fat (HF) food over time, which may contribute to overeating and obesity, has not been determined. We hypothesized that cues paired w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30900
更新日期:2016-08-03 00:00:00
abstract::As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past decade. On the other hand, recent advances in deep learning and transfer learning have shown significant potential in the quantitative medical imaging field, raising the research question of whethe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-80998-y
更新日期:2021-01-14 00:00:00
abstract::The ability to generate germ cells from pluripotent stem cells (PSCs) is valuable for human regenerative medicine and animal breeding. Germ cell-like cells (GCLCs) have been differentiated from mouse and human PSCs, but not from porcine PSCs, which are considered an ideal model for stem cell applications. Here, we dev...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27256
更新日期:2016-06-06 00:00:00
abstract::Magnetic vortex is one of the simplest topologically non-trivial textures in condensed matter physics. It is the ground state of submicron magnetic elements (dots) of different shapes: cylindrical, square etc. So far, the vast majority of the vortex dynamics studies were focused on thin dots with thickness 5-50 nm and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13881
更新日期:2015-09-10 00:00:00
abstract::High-density linkage maps can improve the precision of QTL localization. A high-density SNP-based linkage map containing 3207 markers covering 3072.7 cM of the Brassica napus genome was constructed in the KenC-8 × N53-2 (KNDH) population. A total of 67 and 38 QTLs for seed oil and protein content were identified with ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46295
更新日期:2017-04-10 00:00:00
abstract::Herein, we have fabricated rutile TiO2 nanorod-coupled α-Fe2O3 by a wet-chemical process. It is demonstrated that the visible activities for photoelectrochemical water oxidation and for degrading pollutant of α-Fe2O3 are greatly enhanced after coupling a proper amount of rutile nanorods. The enhanced activity is attri...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06180
更新日期:2014-08-26 00:00:00
abstract::Recent severe European droughts raise the vital question: are we already experiencing measurable changes in drought likelihood that agree with climate change projections? The plethora of drought definitions compounds this question, requiring instead that we ask: how have various types of drought changed, how do these ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14283-2
更新日期:2017-10-25 00:00:00
abstract::The group-IV tin has been hypothesized to possess intriguing electronic properties in an atom-thick hexagonal form. An attractive pathway of producing sizable 2D crystallites of tin is based on deintercalation of bulk compounds with suitable tin frameworks. Here, we have identified a new synthesizable metal distannide...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28369
更新日期:2016-07-08 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-50846-1
更新日期:2019-10-18 00:00:00
abstract::Hatching out from the zona pellucida (ZP) is a crucial step for blastocyst implantation and development. However, it is still unknown whether the location of the hatching site relative to the inner cell mass (ICM) affects embryo implantation and foetal development. Here, we classified hatching blastocysts into three c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59424-2
更新日期:2020-02-12 00:00:00
abstract::The main feature of the present numerical model is to explore the behavior of Maxwell nanoliquid moving within two horizontal rotating disks. The disks are stretchable and subjected to a magnetic field in axial direction. The time dependent characteristics of thermal conductivity have been considered to scrutinize the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74096-8
更新日期:2020-10-13 00:00:00
abstract::A global insight into the roles of multiple P-type calcium ATPase (CA) pumps in sustaining the life of a filamentous fungal pathogen is lacking. Here we elucidated the functions of five CA pumps (Eca1, Spf1 and PmcA/B/C) following previous characterization of Pmr1 in Beauveria bassiana, a fungal insect pathogen. The f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01570-1
更新日期:2017-05-03 00:00:00
abstract::We developed a solvothermal-induced self-assembly approach to construct three dimensional (3D) macroscopic Fe2O3 nanocubes/nitrogen-doped graphene (Fe2O3-NC/GN) aerogel as anode materials for lithium-ion batteries (LIBs). The Fe2O3 nanocubes with length of ~50 nm are homogeneously anchored on 3D GN frameworks and as s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07171
更新日期:2014-11-25 00:00:00
abstract::Treatment as Prevention (TasP) using directly-acting antivirals has been advocated for Hepatitis C Virus (HCV) in people who inject drugs (PWID), but treatment is expensive and TasP's effectiveness is uncertain. Previous modelling has assumed a homogeneously-mixed population or a static network lacking turnover in the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01862-6
更新日期:2017-05-12 00:00:00
abstract::Membrane proteins are distinguished from soluble proteins by their insertion into biological membranes. This insertion is achieved via a noticeable arrangement of hydrophobic amino acids that are exposed at the surface of the protein, and renders the interaction with the aliphatic tails of lipids more energetically fa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17216-1
更新日期:2017-12-05 00:00:00
abstract::Jute fibre is the second most important fibre next to cotton. It is obtained from the bark of plant through microbial retting process. Here we report optimized microbial retting protocol that can lower retting period and produce high fibre quality. A total of 451 bacterial colonies have been isolated from five jute re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61898-z
更新日期:2020-03-20 00:00:00
abstract::Macrophages play a crucial role in the control and elimination of invading Mycobacterium tuberculosis (Mtb), and also serve as the major residence for Mtb. However, the interaction between macrophages and Mtb remains to be clearly determined. Although long noncoding RNAs (lncRNAs) have emerged as key regulators in man...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38963
更新日期:2016-12-14 00:00:00
abstract::We report the high susceptibility of several clinical isolates of Propionibacterium acnes from different sources (skin, bone, wound exudates, abscess or blood contamination) to the head-to-tail cyclized bacteriocin AS-48. This peptide is a feasible candidate for further pharmacological development against this bacteri...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29580-7
更新日期:2018-08-06 00:00:00
abstract::Expression of the mismatch repair gene MutL homolog 1 (MLH1) is silenced in a clinically important subgroup of sporadic colorectal cancers. These cancers exhibit hypermutability with microsatellite instability (MSI) and differ from microsatellite-stable (MSS) colorectal cancers in both prognosis and response to therap...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-019-49952-x
更新日期:2019-09-17 00:00:00
abstract::This study evaluates the forensic utility of 23 autosomal short tandem repeat markers in 400 samples from the Kuwaiti population, of which four markers (D10S1248, D22S1045, D2S441 and SE33) are reported for the first time for Kuwait. All the markers were shown to exhibit no deviation from Hardy-Weinberg equilibrium, n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81425-y
更新日期:2021-01-21 00:00:00