Differential Roles for Six P-Type Calcium ATPases in Sustaining Intracellular Ca2+ Homeostasis, Asexual Cycle and Environmental Fitness of Beauveria bassiana.

abstract：:Real-time impairment of ocular blood flow (OBF) under common carotid artery stenosis (CCAS) has not been ascertained. We aimed to longitudinally assess the impact of CCAS on OBF using a rabbit model. About 75% stenosis was created by tying the common carotid artery with a plastic mandrel using a nylon suture. The plas...

journal_title：Scientific reports

authors： Ismail A,Chen HC,Faye I,Tang TB

更新日期：2020-09-28 00:00:00

abstract：:The Hauraki Gulf, a shallow embayment in north-eastern New Zealand, provides an interesting environment for ecological soundscape research. It is situated on a tectonic plate boundary, contains one of the busiest ports in the southern hemisphere and is home to a diverse range of soniferous animals. The underwater soun...

journal_title：Scientific reports

authors： Putland RL,Constantine R,Radford CA

更新日期：2017-07-18 00:00:00

abstract：:We aimed to develop and validate a multiparametric MR radiomics model using conventional, diffusion-, and perfusion-weighted MR imaging for better prognostication in patients with newly diagnosed glioblastoma. A total of 216 patients with newly diagnosed glioblastoma were enrolled from two tertiary medical centers and...

journal_title：Scientific reports

authors： Park JE,Kim HS,Jo Y,Yoo RE,Choi SH,Nam SJ,Kim JH

更新日期：2020-03-06 00:00:00

abstract：:The microbial community during fermented vegetable production has a large impact on the quality of the final products. Lactic acid bacteria have been well-studied in such processes, but knowledge about the roles of non-lactic acid bacteria is limited. This study aimed to provide useful knowledge about the relationship...

journal_title：Scientific reports

authors： Sawada K,Koyano H,Yamamoto N,Yamada T

更新日期：2021-01-19 00:00:00

abstract：:CCR5 is the major co-receptor for HIV and polymorphisms in the CCR5 gene as well as promoter region that alter cell surface expression have been associated with disease progression. We determined the relationship between CCR5 promoter polymorphisms and CD4 decline and other immunopathological features like immune acti...

journal_title：Scientific reports

authors： Joshi A,Punke EB,Sedano M,Beauchamp B,Patel R,Hossenlopp C,Alozie OK,Gupta J,Mukherjee D,Garg H

更新日期：2017-03-22 00:00:00

abstract：:Hexagonal Fe(3)Sn has many of the desirable properties for a new permanent magnet phase with a Curie temperature of 725 K, a saturation moment of 1.18 MA/m. and anisotropy energy, K1 of 1.8 MJ/m(3). However, contrary to earlier experimental reports, we found both experimentally and theoretically that the easy magnetic...

journal_title：Scientific reports

authors： Sales BC,Saparov B,McGuire MA,Singh DJ,Parker DS

更新日期：2014-11-12 00:00:00

abstract：:Protein tyrosine kinase (PTK) activity has been implicated in pro-inflammatory gene expression following tumor necrosis factor-α (TNF-α) or interkeukin-1β (IL-1β) stimulation. However, the identity of responsible PTK(s) in cytokine signaling have not been elucidated. To evaluate which PTK is critical to promote the cy...

journal_title：Scientific reports

authors： Murphy JM,Jeong K,Rodriguez YAR,Kim JH,Ahn EE,Lim SS

更新日期：2019-05-20 00:00:00

abstract：:This work demonstrates that the rf-sputtering technique, combined with appropriate heat treatments, is potentially effective to develop new materials and devices based on oxide-interface and strain engineering. We report a study of the structural-physical properties relationship of high crystalline quality, highly ori...

journal_title：Scientific reports

authors： H Mŏk HL,Martínez-Aguilar E,Gervacio-Arciniega JJ,Vendrell X,Siqueiros-Beltrones JM,Raymond-Herrera O

更新日期：2017-12-18 00:00:00

abstract：:Hypertension is a public health issue in Iran. The study aimed to estimate the prevalence, awareness, treatment, and control of hypertension, and to explore their determinants among 10,040 Kurdish adults from Ravansar Non-Communicable Disease (RaNCD) cohort study in Iran. Univariate, and multivariate analyses were use...

journal_title：Scientific reports

authors： Rajati F,Hamzeh B,Pasdar Y,Safari R,Moradinazar M,Shakiba E,Bazargan-Hejazi S,Karim H,Najafi F

更新日期：2019-08-27 00:00:00

abstract：:An understanding of all aspects of fluoride metabolism is critical to identify its biological effects and avoid fluoride toxicity in humans. Fluoride metabolism and subsequently its body retention may be affected by physiological responses to acute exercise. This pilot study investigated the effect of exercise on plas...

journal_title：Scientific reports

authors： V Zohoori F,Innerd A,Azevedo LB,Whitford GM,Maguire A

更新日期：2015-11-19 00:00:00

abstract：:Chronic inflammation can be a major driver of the failure of a variety of organs, including chronic kidney disease (CKD). The NLR family pyrin domain-containing 3 (NLRP3) inflammasome has been shown to play a pivotal role in inflammation in a mouse kidney disease model. Nuclear factor erythroid 2-related factor 2 (Nrf...

journal_title：Scientific reports

authors： Sogawa Y,Nagasu H,Iwase S,Ihoriya C,Itano S,Uchida A,Kidokoro K,Taniguchi S,Takahashi M,Satoh M,Sasaki T,Suzuki T,Yamamoto M,Horng T,Kashihara N

更新日期：2017-08-18 00:00:00

abstract：:This study aimed to develop a cationic nanosuspension of chitosan (CS) and methoxy poly(ethylene glycol)-poly(ε-caprolactone) (MPEG-PCL) for ocular delivery of diclofenac (DIC). MPEG-PCL-CS block polymer was synthesized by covalent coupling of MPEG-PCL with CS. The critical micelle concentration of the MPEG-PCL-CS blo...

journal_title：Scientific reports

authors： Shi S,Zhang Z,Luo Z,Yu J,Liang R,Li X,Chen H

更新日期：2015-06-12 00:00:00

abstract：:Bone tissues have trabecular bone with a high bone turnover and cortical bone with a low turnover. The mechanisms by which the turnover rate of these bone tissues is determined remain unclear. Osteocytes secrete sclerostin, a Wnt/β-catenin signaling antagonist, and inhibit bone formation. We found that sclerostin expr...

journal_title：Scientific reports

authors： Koide M,Yamashita T,Murakami K,Uehara S,Nakamura K,Nakamura M,Matsushita M,Ara T,Yasuda H,Penninger JM,Takahashi N,Udagawa N,Kobayashi Y

更新日期：2020-08-13 00:00:00

abstract：:Metabolites detectible in human biofluids are attractive biomarkers for the diagnosis of early Lyme disease (ELD), a vector-borne infectious disease. Urine represents an easily obtained clinical sample that can be applied for diagnostic purposes. However, few studies have explored urine for biomarkers of ELD. In this ...

journal_title：Scientific reports

authors： Pegalajar-Jurado A,Fitzgerald BL,Islam MN,Belisle JT,Wormser GP,Waller KS,Ashton LV,Webb KJ,Delorey MJ,Clark RJ,Molins CR

更新日期：2018-08-15 00:00:00

abstract：:In recent decades Madagascar has experienced significant habitat loss and modification, with minimal understanding of how human land use practices have impacted the evolution of its flora and fauna. In light of ongoing and intensifying anthropogenic pressures, we seek new insight into mechanisms driving genetic variab...

journal_title：Scientific reports

authors： Baden AL,Mancini AN,Federman S,Holmes SM,Johnson SE,Kamilar J,Louis EE Jr,Bradley BJ

更新日期：2019-11-07 00:00:00

abstract：:California has experienced a dry 21(st) century capped by severe drought from 2012 through 2015 prompting questions about hydroclimatic sensitivity to anthropogenic climate change and implications for the future. We address these questions using a Holocene lake sediment record of hydrologic change from the Sierra Neva...

journal_title：Scientific reports

authors： MacDonald GM,Moser KA,Bloom AM,Potito AP,Porinchu DF,Holmquist JR,Hughes J,Kremenetski KV

更新日期：2016-09-15 00:00:00

abstract：:Multi-junction (MJ) solar cells are one of the most promising technologies achieving high sunlight to electricity conversion efficiency. Resistive losses constitute one of the main underlying mechanisms limiting their efficiency under high illumination. In this paper, we study, by numerical modeling, the extent to whi...

journal_title：Scientific reports

authors： Zeitouny J,Katz EA,Dollet A,Vossier A

更新日期：2017-05-11 00:00:00

abstract：:Development of multidrug resistance (MDR) is an almost universal phenomenon in patients with ovarian cancer, and this severely limits the ultimate success of chemotherapy in the clinic. Overexpression of the MDR1 gene and corresponding P-glycoprotein (Pgp) is one of the best known MDR mechanisms. MDR1 siRNA based stra...

journal_title：Scientific reports

authors： Yang X,Iyer AK,Singh A,Choy E,Hornicek FJ,Amiji MM,Duan Z

更新日期：2015-02-17 00:00:00

abstract：:Geometric mean concentrations of fecal indicator bacteria E. coli and enterococci are commonly used to evaluate the microbial quality of irrigation, recreation, and other types of waters, as well in watershed-scale microbial water quality modeling. It is not known how the uncertainty of those geometric mean concentrat...

journal_title：Scientific reports

authors： Jeon DJ,Pachepsky Y,Harriger MD,Zhu R,Coppock C

更新日期：2020-02-03 00:00:00

abstract：:We investigated the ocular surface (OS) system modifications after completely successful glaucoma surgery in thirty-eight patients undergoing trabeculectomy (surgical group), using laser scanning confocal microscopy (LSCM) and impression cytology (IC). Twenty-six medically controlled glaucomatous patients served as co...

journal_title：Scientific reports

authors： Agnifili L,Brescia L,Oddone F,Sacchi M,D'Ugo E,Di Marzio G,Perna F,Costagliola C,Mastropasqua R

更新日期：2019-08-05 00:00:00

abstract：:There were significant differences in response and pharmacokinetic characteristics to the peginterferon α2a treatment among Chronic Hepatitis B (CHB) patients. The aim of this study is to identify factors which could significantly impact the peginterferon α2a pharmacokinetic characteristics in CHB patients. There were...

journal_title：Scientific reports

authors： Bi J,Li X,Liu J,Chen D,Li S,Hou J,Zhou Y,Zhu S,Zhao Z,Qin E,Wei Z

更新日期：2017-08-11 00:00:00

abstract：:The monitoring and early detection of abnormalities or variations in the cardiac cycle functionality are very critical practices and have significant impact on the prevention of heart diseases and their associated complications. Currently, in the field of biomedical engineering, there is a growing need for devices cap...

journal_title：Scientific reports

authors： Ahmad MA

更新日期：2016-11-17 00:00:00

abstract：:In recent years, the monolithic material has been developed increasingly in the high performance liquid phase field, and it could also be applied in the field of catalyst, as a monolithic catalyst carrier, since it has a large specific surface area, and could be customized based on the mould. The monolithic catalyst i...

journal_title：Scientific reports

authors： Tsai SB,Ma H

更新日期：2018-11-09 00:00:00

abstract：:Women who have previously had an induced abortion (IA) before their first birth have been associated with preterm birth (PTB). However, previous studies on the PTB are inconsistent. Therefore, the aim of this study was to clarify the association between IA and PTB and low birth weight (LBW) for first-time mothers. A t...

journal_title：Scientific reports

authors： Ke L,Lin W,Liu Y,Ou W,Lin Z

更新日期：2018-03-29 00:00:00

abstract：:The increasing demand for healthy baked goods boosted studies on sourdough microbiota with beneficial metabolic traits, to be used as potential functional starters. Here, 139 yeasts isolated from cereal-based fermented foods were in vitro characterized for their phytase and antioxidant activities. The molecular charac...

journal_title：Scientific reports

authors： Palla M,Blandino M,Grassi A,Giordano D,Sgherri C,Quartacci MF,Reyneri A,Agnolucci M,Giovannetti M

更新日期：2020-07-30 00:00:00

abstract：:Bats are the only mammals capable of true, powered flight, which drives an extremely high metabolic rate. The "Free Radical Theory of Ageing" (FTRA) posits that a high metabolic rate causes mitochondrial heteroplasmy and the progressive ageing phenotype. Contrary to this, bats are the longest-lived order of mammals gi...

journal_title：Scientific reports

authors： Jebb D,Foley NM,Whelan CV,Touzalin F,Puechmaille SJ,Teeling EC

更新日期：2018-09-11 00:00:00

abstract：:Interactions of high-frequency radio waves (RF) with biological tissues are currently being investigated as a therapeutic platform for non-invasive cancer hyperthermia therapy. RF delivers thermal energy into tissues, which increases intra-tumoral drug perfusion and blood-flow. Herein, we describe an optical-based met...

journal_title：Scientific reports

authors： Ware MJ,Krzykawska-Serda M,Chak-Shing Ho J,Newton J,Suki S,Law J,Nguyen L,Keshishian V,Serda M,Taylor K,Curley SA,Corr SJ

更新日期：2017-03-13 00:00:00

abstract：:Here we investigated whether endothelial colony forming cells (ECFC) and mesenchymal progenitor cells (MPC) form vascular networks and restore blood flow in ischemic skeletal muscle, and whether host myeloid cells play a role. ECFC + MPC, ECFC alone, MPC alone, or vehicle alone were injected into the hind limb ischemi...

journal_title：Scientific reports

authors： Kang KT,Lin RZ,Kuppermann D,Melero-Martin JM,Bischoff J

更新日期：2017-04-10 00:00:00

abstract：:Oligomannose-type glycans on HIV-1 gp120 form a patch that is targeted by several broadly neutralizing antibodies (bnAbs) and that therefore is of interest to vaccine design. However, attempts to elicit similar oligomannose-specific bnAbs by immunizing with oligomannosidic glycoconjugates have only been modestly succe...

journal_title：Scientific reports

authors： Bruxelle JF,Kirilenko T,Qureshi Q,Lu N,Trattnig N,Kosma P,Pantophlet R

更新日期：2020-05-05 00:00:00

abstract：:The exopeptidases of family S46 are exceptional, as the closest homologs of these enzymes are the endopeptidases of clan PA. The three-dimensional structure of S46 enzymes is unknown and only one of the catalytic residues, the serine, has been identified. The catalytic histidine and aspartate residues are not experime...

journal_title：Scientific reports

authors： Suzuki Y,Sakamoto Y,Tanaka N,Okada H,Morikawa Y,Ogasawara W

更新日期：2014-03-06 00:00:00