Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Malik B,Bhattacharyya Sdoi
10.1038/s41598-019-50846-1subject
Has Abstractpub_date
2019-10-18 00:00:00pages
15184issue
1issn
2045-2322pii
10.1038/s41598-019-50846-1journal_volume
9pub_type
已发布勘误abstract::Keratin 15 (K15), a type I keratin, which pairs with K5 in epidermis, has been used extensively as a biomarker for stem cells. Two commercial antibodies, LHK15, a mouse monoclonal and EPR1614Y, a rabbit monoclonal, have been widely employed to study K15 expression. Here we report differential reactivity of these antib...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38163-5
更新日期:2019-02-13 00:00:00
abstract::Although the use of metabarcoding to identify taxa in DNA mixtures is widely approved, its reliability in quantifying taxon abundance is still the subject of debate. In this study we investigated the relationships between the amount of pollen grains in mock solutions and the abundance of high-throughput sequence reads...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61198-6
更新日期:2020-03-06 00:00:00
abstract::The evolution to bipedalism forced humans to develop suitable strategies for dynamically controlling their balance, ensuring stability, and preventing falling. The natural aging process and traumatic events such as lower-limb loss can alter the human ability to control stability significantly increasing the risk of fa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46721
更新日期:2017-05-11 00:00:00
abstract::Accumulating evidence indicates the association between obesity and lung function. However, no previous study has examined whether obesity affects lung function in normal weight participants with high body fat. We hypothesized that subjects with normal weight obesity (NWO) were inversely associated with lung function ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38804-3
更新日期:2019-06-20 00:00:00
abstract::Pupillary light reflex (PLR) is an involuntary response where the pupil size changes with luminance. Studies have shown that PLR response was altered in children with autism spectrum disorders (ASDs) and other neurological disorders. However, PLR in infants and toddlers is still understudied. We conducted a longitudin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58254-6
更新日期:2020-01-27 00:00:00
abstract::Delivery and expression of recombinant genes, a key methodology for many applications in biological research, remains a challenge especially for mature neurons. Here, we report easy, highly efficient and well tolerated transduction of adult peripheral and central neuronal populations of diverse species in culture usin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38928
更新日期:2016-12-13 00:00:00
abstract::Several mosquito species have been described as vectors for the Zika virus (ZIKV), such as those in the Aedes, Anopheles, Mansonia and Culex genera. Our previous survey studies were found the ZIKV RNA positive in both male, female and larvae of Culex quinquefasciatus Say and Aedes aegypti (L.) mosquitoes collected fro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41727-8
更新日期:2019-03-27 00:00:00
abstract::An effective metal oxide coating with solution processes by the metal organic decomposition method as deposited at room temperature (RT) poses great challenge. In this study, we report the characterization and evaluation of the semiconductor properties of a zinc hydroxide thin film with RT just as deposition by soluti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27953-6
更新日期:2018-07-20 00:00:00
abstract::Proper determination of agonist efficacy is essential in the assessment of agonist selectivity and signalling bias. Agonist efficacy is a relative term that is dependent on the system in which it is measured, especially being dependent on receptor expression level. The operational model (OM) of functional receptor ago...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40993-w
更新日期:2019-03-15 00:00:00
abstract::Recently, the discovery of room temperature magnetoelectricity in organic charge transfer complexes has reignited interest in the multiferroic field. The solution processed, large-area and low cost organic semiconductor materials offer new possibilities for the functional all organic multiferroic devices. Here we repo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28656
更新日期:2016-06-23 00:00:00
abstract::Memory function deficits induced by Alzheimer's disease (AD) are believed to be one of the causes of an increased risk of tripping in patients. Working memory contributes to accurate stepping over obstacles during locomotion, and AD-induced deficits of this memory function may lead to an increased risk of contact with...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07220
更新日期:2014-11-27 00:00:00
abstract::Toll-like receptor 7 (TLR7) mediates autoantigen and viral RNA-induced cytokine production. Increased TLR7 expression in human atherosclerotic lesions suggests its involvement in atherogenesis. Here we demonstrated TLR7 expression in macrophages, smooth muscle cells (SMCs), and endothelial cells from mouse atheroscler...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00977-0
更新日期:2017-04-12 00:00:00
abstract::We propose a new method to extend the path length tunability of rotary delay-lines. This method was shown to achieve a duty cycle of >80% and repetition rates of over 40 kHz. The new method relies on a new multi-segmented micro-machined mirror and serial injection of a single reflection onto separate segments of this ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09576-5
更新日期:2017-08-24 00:00:00
abstract::We have developed a framework to convert an arbitrary integer factorization problem to an executable Ising model by first writing it as an optimization function then transforming the k-bit coupling (k ≥ 3) terms to quadratic terms using ancillary variables. Our resource-efficient method uses [Formula: see text] binary...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36058-z
更新日期:2018-12-05 00:00:00
abstract::There were significant differences in response and pharmacokinetic characteristics to the peginterferon α2a treatment among Chronic Hepatitis B (CHB) patients. The aim of this study is to identify factors which could significantly impact the peginterferon α2a pharmacokinetic characteristics in CHB patients. There were...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08205-5
更新日期:2017-08-11 00:00:00
abstract::Recently, minocycline, a tetracycline antibiotic, has been reported to improve symptoms of psychiatric disorders and to facilitate sober decision-making in healthy human subjects. Here we show that minocycline also reduces the risk of the 'honey trap' during an economic exchange. Males tend to cooperate with physicall...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01685
更新日期:2013-01-01 00:00:00
abstract::Determining the success of eradication of an invasive species requires a way to decide when its risk of reoccurrence has become acceptably low. In Japan, the area populated by the Argentine ant, Linepithema humile (Mayr), is expanding, and eradication via chemical treatment is ongoing at various locations. One such pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03516-z
更新日期:2017-06-13 00:00:00
abstract::Tea plant is a typical fluorine (F) accumulator. F concentration in mature tea leaves is several hundred times higher than that in normal field crops. Long-term consumption of teas with high level F will increase the risks of dental and skeletal fluorosis. The mechanism of F accumulation in tea stands unclear. RNA-Seq...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08587-6
更新日期:2017-08-29 00:00:00
abstract::Hair loss is a common medical problem. In this study, we investigated the proliferation, migration, and growth factor expression of human dermal papilla (DP) cells in the presence or absence of treatment with mesenchymal stem cell extracellular vesicles (MSC-EVs). In addition, we tested the efficacy of MSC-EV treatmen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15505-3
更新日期:2017-11-14 00:00:00
abstract::Currently, light pollution has become a nonnegligible issue in our daily life. Artificial light sources with high color temperature were deem to be the major pollution source, which could induce several adverse effects on human's health. In our previous research, we have firstly developed an artificial indoor light wi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43864-6
更新日期:2019-05-17 00:00:00
abstract::Varroa destructor mites express strong avoidance of the Apis cerana worker brood in the field. The molecular mechanism for this phenomenon remains unknown. We identified a Varroa toxic protein (VTP), which exhibited toxic activity toward A. cerana worker larvae, in the saliva of these mites, and expressed VTP in an Es...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21736-9
更新日期:2018-02-21 00:00:00
abstract::Metamaterial absorbers can provide good solutions for radar-cross-section (RCS) reduction. In spite of their attractive features of thinness, lightness, and low cost, resonant metamaterial absorbers have a drawback of narrow bandwidth. For practical radar applications, wideband absorbers are necessary. In this paper, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31823
更新日期:2016-08-22 00:00:00
abstract::Wildfires burn large parts of the tropics every year, shaping ecosystem structure and functioning. Yet the complex interplay between climate, vegetation and human factors that drives fire dynamics is still poorly understood. Here we show that on all continents, except Australia, tropical fire regimes change drasticall...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14654-9
更新日期:2017-10-30 00:00:00
abstract::The centrosome is the microtubule organizing center of human cells and facilitates a myriad of cellular functions including organization of the mitotic spindle to ensure faithful chromosome segregation during mitosis, cell polarization and migration, and primary cilia formation. A numerical increase in centrosomes, or...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68629-4
更新日期:2020-07-17 00:00:00
abstract::The detection and characterization of highly enriched uranium (HEU) presents a large challenge in the non-proliferation field. HEU has a low neutron emission rate and most gamma rays are low energy and easily shielded. To address this challenge, an instrument known as the dual-particle imager (DPI) was used with a por...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08253-x
更新日期:2017-08-11 00:00:00
abstract::Conformational behavior of intrinsically disordered proteins, such as Phe-Gly repeat domains, alters drastically when they are confined in, and tethered to, nan channels. This has challenged our understanding of how they serve to selectively facilitate translocation of nuclear transport receptor (NTR)-bearing macromol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29991
更新日期:2016-07-29 00:00:00
abstract::Efficient interventions to reduce blood triglycerides are few; newer and more tolerable intervention targets are needed. Understanding the molecular mechanisms underlying blood triglyceride levels variation is key to identifying new therapies. To explore the role of epigenetic mechanisms on triglyceride levels, a bloo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09552-z
更新日期:2017-09-11 00:00:00
abstract::Measuring toxicity is one of the main steps in drug development. Hence, there is a high demand for computational models to predict the toxicity effects of the potential drugs. In this study, we used a dataset, which consists of four toxicity effects:mutagenic, tumorigenic, irritant and reproductive effects. The propos...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38660
更新日期:2016-12-09 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-54609-w
更新日期:2019-11-27 00:00:00
abstract::We previously reported that induction of the adipocyte-specific gene adiponectin (Adipoq) during 3T3-L1 adipocyte differentiation is closely associated with epigenetic memory histone H3 acetylation on the transcribed region of the gene. We used 3T3-L1 adipocytes and Brd4 heterozygous mice to investigate whether the in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12342-2
更新日期:2017-09-20 00:00:00