Incubation of food craving is independent of macronutrient composition.

Abstract:

:Cues previously paired with rewarding stimuli induce a time-dependent increase in the motivational craving state (incubation of craving). Whether there is an increase in craving for high-fat (HF) food over time, which may contribute to overeating and obesity, has not been determined. We hypothesized that cues paired with HF pellets would elicit a greater incubation of craving effect than those paired with standard chow (SC) pellets. Rats exposed to cues associated with either HF or SC pellets demonstrated equivalent levels of craving over an abstinence period of 30 days. Diet preference tests between SC pellets and LabDiet revealed that SC pellets were preferred over LabDiet. Rats reared on SC pellets exclusively, did not display incubation of craving for SC pellets, suggesting that prior history with the food plays an important role in cue-induced seeking behavior. Results identified cues previously associated with food undergo a comparable magnitude of incubation of craving. When ingestive behavior was measured after 30 days of abstinence, rats significantly increased their consumption of HF pellets. Our results indicate that food cues gain importance over time, trigger increased approach behaviors, and increased consumption of HF food following abstinence. This may contribute to overeating and the development of obesity.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Darling RA,Dingess PM,Schlidt KC,Smith EM,Brown TE

doi

10.1038/srep30900

subject

Has Abstract

pub_date

2016-08-03 00:00:00

pages

30900

issn

2045-2322

pii

srep30900

journal_volume

6

pub_type

杂志文章
  • Emergent complex network geometry.

    abstract::Networks are mathematical structures that are universally used to describe a large variety of complex systems such as the brain or the Internet. Characterizing the geometrical properties of these networks has become increasingly relevant for routing problems, inference and data mining. In real growing networks, topolo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep10073

    authors: Wu Z,Menichetti G,Rahmede C,Bianconi G

    更新日期:2015-05-18 00:00:00

  • Electro-optical effects of organic N-benzyl-2-methyl-4-nitroaniline dispersion in nematic liquid crystals.

    abstract::The dispersion of organic N-benzyl-2-methyl-4-nitroaniline (BNA) in nematic liquid crystals (LCs) is studied. BNA doping decreases the threshold voltage of cell because of the reduced splay elastic constant and increased dielectric anisotropy of the LC mixture. When operated in the high voltage difference condition, t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-71306-1

    authors: Selvaraj P,Subramani K,Srinivasan B,Hsu CJ,Huang CY

    更新日期:2020-08-31 00:00:00

  • Spatially- and vector-resolved momentum flux lost to a wall in a magnetic nozzle rf plasma thruster.

    abstract::Most of the artificial low-pressure plasmas contact with physical walls in laboratories; the plasma loss at the wall significantly affects the plasma device performance, e.g., an electric propulsion device. Near the surface of the wall, ions are spontaneously accelerated by a sheath and deliver their momentum and ener...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-58022-6

    authors: Takahashi K,Sugawara T,Ando A

    更新日期:2020-01-23 00:00:00

  • Association of plasma free amino acids with hyperuricemia in relation to diabetes mellitus, dyslipidemia, hypertension and metabolic syndrome.

    abstract::Previous studies demonstrated independent contributions of plasma free amino acids (PFAAs) and high uric acid (UA) concentrations to increased risks of lifestyle-related diseases (LSRDs), but the important associations between these factors and LSRDs remain unknown. We quantified PFAAs and UA amongst Japanese subjects...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17710-6

    authors: Mahbub MH,Yamaguchi N,Takahashi H,Hase R,Ishimaru Y,Sunagawa H,Amano H,Kobayashi-Miura M,Kanda H,Fujita Y,Yamamoto H,Yamamoto M,Kikuchi S,Ikeda A,Kageyama N,Nakamura M,Tanabe T

    更新日期:2017-12-15 00:00:00

  • A continuous evolution system for contracting the host range of bacteriophage T7.

    abstract::Bacteriophage T7 is an intracellular parasite that recognizes its host via its tail and tail fiber proteins, known as receptor-binding proteins (RBPs). The RBPs attach to specific lipopolysaccharide (LPS) features on the host. Various studies have shown expansion of the phage's host range via mutations in the genes en...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-57221-0

    authors: Holtzman T,Globus R,Molshanski-Mor S,Ben-Shem A,Yosef I,Qimron U

    更新日期:2020-01-15 00:00:00

  • A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins.

    abstract::Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in specific integrins, or their deregulated expression, are associated with a variety of diseases. In t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep39805

    authors: Kapp TG,Rechenmacher F,Neubauer S,Maltsev OV,Cavalcanti-Adam EA,Zarka R,Reuning U,Notni J,Wester HJ,Mas-Moruno C,Spatz J,Geiger B,Kessler H

    更新日期:2017-01-11 00:00:00

  • Significance of dopamine D1 receptor signalling for steroidogenic differentiation of human induced pluripotent stem cells.

    abstract::Human induced pluripotent stem cells (hiPSCs) are expected to be both a revolutionary cell source for regenerative medicine and a powerful tool to investigate the molecular mechanisms underlying human cell development in vitro. In the present study, we tried to elucidate the steroidogenic differentiation processes usi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-15485-4

    authors: Matsuo K,Sone M,Honda-Kohmo K,Toyohara T,Sonoyama T,Taura D,Kojima K,Fukuda Y,Ohno Y,Inoue M,Ohta A,Osafune K,Nakao K,Inagaki N

    更新日期:2017-11-09 00:00:00

  • Optimization of a MT1-MMP-targeting Peptide and Its Application in Near-infrared Fluorescence Tumor Imaging.

    abstract::Membrane type 1 metalloproteinase (MT1-MMP) is an important regulator of cancer invasion, growth and angiogenesis, thus making it an attractive target for cancer imaging and therapy. A non-substrate peptide (MT1-AF7p) that bonded to the "MT-Loop" region of MT1-MMP was identified by using a phage-displayed peptide libr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-28493-9

    authors: Ren L,Wang Y,Zhu L,Shen L,Zhang J,Wang J,Li H,Zheng Q,Yu D,Fang X

    更新日期:2018-07-09 00:00:00

  • Sex Ratio Elasticity Influences the Selection of Sex Ratio Strategy.

    abstract::There are three sex ratio strategies (SRS) in nature-male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton's local mate competition (LMC) and Clark's local resource compe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep39807

    authors: Wang Y,Wang R,Li Y,Sam Ma Z

    更新日期:2016-12-23 00:00:00

  • Genome-scale analysis identifies NEK2, DLGAP5 and ECT2 as promising diagnostic and prognostic biomarkers in human lung cancer.

    abstract::This study aims to identify promising biomarkers for the early detection of lung cancer and evaluate the prognosis of lung cancer patients. Genome-wide mRNA expression data obtained from the Gene Expression Omnibus (GSE19188, GSE18842 and GSE40791), including 231 primary tumor samples and 210 normal samples, were used...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-08615-5

    authors: Shi YX,Yin JY,Shen Y,Zhang W,Zhou HH,Liu ZQ

    更新日期:2017-08-14 00:00:00

  • Audio motor training improves mobility and spatial cognition in visually impaired children.

    abstract::Since it has been demonstrated that spatial cognition can be affected in visually impaired children, training strategies that exploit the plasticity of the human brain should be early adopted. Here we developed and tested a new training protocol based on the reinforcement of audio-motor associations and thus supportin...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章

    doi:10.1038/s41598-019-39981-x

    authors: Cappagli G,Finocchietti S,Cocchi E,Giammari G,Zumiani R,Cuppone AV,Baud-Bovy G,Gori M

    更新日期:2019-03-01 00:00:00

  • Author Correction: Potential damaging mutation in LRP5 from genome sequencing of the first reported chimpanzee with the Chiari malformation.

    abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-018-24993-w

    authors: Solis-Moruno M,de Manuel M,Hernandez-Rodriguez J,Fontsere C,Gomara-Castaño A,Valsera-Naranjo C,Crailsheim D,Navarro A,Llorente M,Riera L,Feliu-Olleta O,Marques-Bonet T

    更新日期:2018-05-04 00:00:00

  • Electronic structure engineering of Cu2O film/ZnO nanorods array all-oxide p-n heterostructure for enhanced photoelectrochemical property and self-powered biosensing application.

    abstract::We have engineered the electronic structure at the interface between Cu2O and ZnO nanorods (NRs) array, through adjusting the carrier concentration of Cu2O. The electrodeposition of Cu2O at pH 11 acquired the highest carrier concentration, resulting in the largest interfacial electric field between Cu2O and ZnO, which...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07882

    authors: Kang Z,Yan X,Wang Y,Bai Z,Liu Y,Zhang Z,Lin P,Zhang X,Yuan H,Zhang X,Zhang Y

    更新日期:2015-01-20 00:00:00

  • Water-Soluble Metalated Covalent Organic Nanobelts with Improved Bioavailability for Protein Transportation.

    abstract::An available pathway to prepare the ionized covalent organic nanosheets (iCONs) has been proposed by a metal-assisted aqueous-phase exfoliation route from covalent organic frameworks. The soluble and belt-shaped iCONs could immobilize a large quantity of proteins (2.73 mg/mg, BSA/iCONs) and hence serve as transporters...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-23744-1

    authors: Kong W,Wan J,Namuangruk S,Guo J,Wang C

    更新日期:2018-04-03 00:00:00

  • Broadband frequency-selective spoof surface plasmon polaritons on ultrathin metallic structure.

    abstract::We propose an ultrathin metallic structure to produce frequency-selective spoof surface plasmon polaritons (SPPs) in the microwave and terahertz frequencies. Designed on a thin dielectric substrate, the ultrathin metallic structure is composed of two oppositely oriented single-side corrugated strips, which are coupled...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep08165

    authors: Yin JY,Ren J,Zhang HC,Pan BC,Cui TJ

    更新日期:2015-02-02 00:00:00

  • Complex history of dog (Canis familiaris) origins and translocations in the Pacific revealed by ancient mitogenomes.

    abstract::Archaeological evidence suggests that dogs were introduced to the islands of Oceania via Island Southeast Asia around 3,300 years ago, and reached the eastern islands of Polynesia by the fourteenth century AD. This dispersal is intimately tied to human expansion, but the involvement of dogs in Pacific migrations is no...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-27363-8

    authors: Greig K,Gosling A,Collins CJ,Boocock J,McDonald K,Addison DJ,Allen MS,David B,Gibbs M,Higham CFW,Liu F,McNiven IJ,O'Connor S,Tsang CH,Walter R,Matisoo-Smith E

    更新日期:2018-06-14 00:00:00

  • Quantitative x-ray phase imaging at the nanoscale by multilayer Laue lenses.

    abstract::For scanning x-ray microscopy, many attempts have been made to image the phase contrast based on a concept of the beam being deflected by a specimen, the so-called differential phase contrast imaging (DPC). Despite the successful demonstration in a number of representative cases at moderate spatial resolutions, these ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep01307

    authors: Yan H,Chu YS,Maser J,Nazaretski E,Kim J,Kang HC,Lombardo JJ,Chiu WK

    更新日期:2013-01-01 00:00:00

  • A new high-resolution melting analysis for the detection and identification of Plasmodium in human and Anopheles vectors of malaria.

    abstract::Among vector-borne diseases malaria is the leading cause of morbidity in the world, with more than 200 million cases per year and a large number of deaths. The techniques traditionally used for the detection of Plasmodium in humans and Anopheles mosquitoes include microscopy, IRMA, ELISA, antibody or molecular assays,...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-36515-9

    authors: Murillo E,Muskus C,Agudelo LA,Vélez ID,Ruiz-Lopez F

    更新日期:2019-02-08 00:00:00

  • Electrically Enhanced Self-Thermophoresis of Laser-Heated Janus Particles under a Rotating Electric Field.

    abstract::The motion of a laser-heated Janus particle is experimentally measured under a rotating electric field. Directionally circular motions of the Janus particle following or countering the direction of the rotating electric field are observed in the low-frequency region (from 1 to 6 kHz) depending on the direction of elec...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-24343-w

    authors: Chen YL,Yang CX,Jiang HR

    更新日期:2018-04-13 00:00:00

  • Impact of dietary resistant starch type 4 on human gut microbiota and immunometabolic functions.

    abstract::Dietary modulation of the gut microbiota impacts human health. Here we investigated the hitherto unknown effects of resistant starch type 4 (RS4) enriched diet on gut microbiota composition and short-chain fatty acid (SCFA) concentrations in parallel with host immunometabolic functions in twenty individuals with signs...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28797

    authors: Upadhyaya B,McCormack L,Fardin-Kia AR,Juenemann R,Nichenametla S,Clapper J,Specker B,Dey M

    更新日期:2016-06-30 00:00:00

  • Observations of Deep Current at the Western Boundary of the Northern Philippine Basin.

    abstract::One-year time series of current velocities and hydrographic parameters based on four deep moorings deployed east of the Luzon Strait are employed to study the deep current at the western boundary (DCWB) of the northern Philippine Basin. While the mean current is relatively weak, the DCWB is highly variable on an intra...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-32541-9

    authors: Zhou C,Zhao W,Tian J,Yang Q,Huang X,Zhang Z,Qu T

    更新日期:2018-09-25 00:00:00

  • Enhancing near-infrared photoluminescence from single-walled carbon nanotubes by defect-engineering using benzoyl peroxide.

    abstract::Single-walled carbon nanotubes (SWCNTs) have been modified with ester groups using typical organic radical chemistry. Consequently, traps for mobile excitons have been created, which enhanced the optical properties of the material. The proposed methodology combines the benefits of mainstream approaches to create lumin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-76716-9

    authors: Przypis L,Krzywiecki M,Niidome Y,Aoki H,Shiraki T,Janas D

    更新日期:2020-11-16 00:00:00

  • Clinical Evaluation of the Immunochromatographic System Using Silver Amplification for the Rapid Detection of Mycoplasma pneumoniae.

    abstract::Mycoplasma pneumoniae infection is conventionally diagnosed using serum antibody testing, microbial culture, and genetic testing. Recently, immunochromatography-based rapid mycoplasma antigen test kits have been developed and commercialised for rapid diagnosis of M. pneumoniae infection. However, as these kits do not ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-19734-y

    authors: Namkoong H,Yamazaki M,Ishizaki M,Endo I,Harada N,Aramaki M,Tanaka Y,Kaburagi S,Ichikawa M,Ohata T,Sakaguchi S,Saito F,Nakao A,Yuki H,Mitamura K

    更新日期:2018-01-23 00:00:00

  • Bacillus amyloliquefaciens SQR9 induces dendritic cell maturation and enhances the immune response against inactivated avian influenza virus.

    abstract::The objective of this study was to evaluate the stimulatory effects of Bacillus amyloliquefaciens SQR9 on dendritic cells (DCs) and to verify its ability to enhance the immune response by modulating DC maturation. The results demonstrated that B. amyloliquefaciens SQR9 can adhere to the nasal epithelium and be taken u...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep21363

    authors: Huang L,Qin T,Yin Y,Gao X,Lin J,Yang Q,Yu Q

    更新日期:2016-02-19 00:00:00

  • Factors affecting pitch discrimination performance in a cohort of extensively phenotyped healthy volunteers.

    abstract::Despite efforts to characterize the different aspects of musical abilities in humans, many elements of this complex area remain unknown. Musical abilities are known to be associated with factors like intelligence, training, and sex, but a comprehensive evaluation of the simultaneous impact of multiple factors has not ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16526-8

    authors: Smith LM,Bartholomew AJ,Burnham LE,Tillmann B,Cirulli ET

    更新日期:2017-11-28 00:00:00

  • Comparison of radiotherapy techniques with flattening filter and flattening filter-free in lung radiotherapy according to the treatment volume size.

    abstract::In external radiotherapy (RT), the use of flattening filter-free (FFF) radiation beams obtained by removing the flattening filter (FF) in standard linear accelerators is rapidly increasing, and the benefits of clinical use are the issue of research. Advanced treatment techniques have increased the interest in the oper...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-66079-6

    authors: Arslan A,Sengul B

    更新日期:2020-06-02 00:00:00

  • Symbolic regression of generative network models.

    abstract::Networks are a powerful abstraction with applicability to a variety of scientific fields. Models explaining their morphology and growth processes permit a wide range of phenomena to be more systematically analysed and understood. At the same time, creating such models is often challenging and requires insights that ma...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep06284

    authors: Menezes T,Roth C

    更新日期:2014-09-05 00:00:00

  • Observation of magnetic domains in graphene magnetized by controlling temperature, strain and magnetic field.

    abstract::Since the production of ferromagnetic graphene as an extremely important matter in spintronics has made a revolution in future technology, a great deal of efforts has recently been done to reach a simple and cost-effective method. Up to now, controlling the magnetic properties at extremely low temperature have been in...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-78262-w

    authors: Alimohammadian M,Sohrabi B

    更新日期:2020-12-07 00:00:00

  • Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development.

    abstract::Congenital glaucoma (CG) is a heterogeneous, inherited and severe optical neuropathy that originates from maldevelopment of the anterior segment of the eye. To identify new disease genes, we performed whole-exome sequencing of 26 unrelated CG patients. In one patient we identified two rare, recessive and hypermorphic ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep46175

    authors: Ferre-Fernández JJ,Aroca-Aguilar JD,Medina-Trillo C,Bonet-Fernández JM,Méndez-Hernández CD,Morales-Fernández L,Corton M,Cabañero-Valera MJ,Gut M,Tonda R,Ayuso C,Coca-Prados M,García-Feijoo J,Escribano J

    更新日期:2017-04-11 00:00:00

  • Metabolomic networks and pathways associated with feed efficiency and related-traits in Duroc and Landrace pigs.

    abstract::Improving feed efficiency (FE) is a major goal of pig breeding, reducing production costs and providing sustainability to the pig industry. Reliable predictors for FE could assist pig producers. We carried out untargeted blood metabolite profiling in uncastrated males from Danbred Duroc (n = 59) and Danbred Landrace (...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-57182-4

    authors: Carmelo VAO,Banerjee P,da Silva Diniz WJ,Kadarmideen HN

    更新日期:2020-01-14 00:00:00