Water-Soluble Metalated Covalent Organic Nanobelts with Improved Bioavailability for Protein Transportation.

abstract：:Neurotransmitter release from the presynaptic terminal is under very precise spatial and temporal control. Following neurotransmitter release, synaptic vesicles are recycled by endocytosis and refilled with neurotransmitter. During the exocytosis event leading to release, SNARE proteins provide most of the mechanical ...

journal_title：Scientific reports

authors： Craig TJ,Anderson D,Evans AJ,Girach F,Henley JM

更新日期：2015-12-04 00:00:00

abstract：:A generalization of the Raman scattering (RS) spectrum, the Raman excitation map (REM) is a hyperspectral two-dimensional (2D) data set encoding vibrational spectra, electronic spectra and their coupling. Despite the great potential of REM for optical sensing and characterization with remarkable sensitivity and select...

journal_title：Scientific reports

authors： Finnie P,Ouyang J,Lefebvre J

更新日期：2020-06-08 00:00:00

abstract：:We aimed to assess the ankle-brachial index (ABI) in patients with Graves' disease. In the cross-sectional assessments, 81 patients with drug-naïve Graves' disease and 235 with euthyroidism were enrolled. ABI and vascular cell adhesion molecule-1 (VCAM-1) levels were assessed. In the prospective follow-up, 32 patients...

journal_title：Scientific reports

authors： Li YH,Lee IT

更新日期：2020-10-13 00:00:00

abstract：:Term preeclampsia (tPE), ≥37 weeks, is the most common form of PE and the most difficult to predict. Little is known about its pathogenesis. This study aims to elucidate the pathogenesis and assess early prediction of tPE using serial integrated metabolomic and proteomic systems biology approaches. Serial first- (11-1...

journal_title：Scientific reports

authors： Bahado-Singh R,Poon LC,Yilmaz A,Syngelaki A,Turkoglu O,Kumar P,Kirma J,Allos M,Accurti V,Li J,Zhao P,Graham SF,Cool DR,Nicolaides K

更新日期：2017-11-23 00:00:00

abstract：:Heart failure with preserved ejection fraction (HFpEF) affects more women than men, suggesting gender to play a major role in disease evolution. However, studies investigating gender differences in HFpEF are limited. In the present study we aimed to describe gender differences in a well-characterized HFpEF cohort. Con...

journal_title：Scientific reports

authors： Duca F,Zotter-Tufaro C,Kammerlander AA,Aschauer S,Binder C,Mascherbauer J,Bonderman D

更新日期：2018-01-18 00:00:00

abstract：:Macrophages and resident microglia play an import role in the secondary neuroinflammation response following spinal cord injury. Reprogramming of macrophage/microglia polarization is an import strategy for spinal cord injury restoration. Low-level laser therapy (LLLT) is a noninvasive treatment that has been widely us...

journal_title：Scientific reports

authors： Song JW,Li K,Liang ZW,Dai C,Shen XF,Gong YZ,Wang S,Hu XY,Wang Z

更新日期：2017-04-04 00:00:00

abstract：:Myocardial ischemia culminates in ATP production impairment, ionic derangement and cell death. The provision of metabolic substrates during reperfusion significantly increases heart tolerance to ischemia by improving mitochondrial performance. Under normoxia, glutamate contributes to myocardial energy balance as subst...

journal_title：Scientific reports

authors： Maiolino M,Castaldo P,Lariccia V,Piccirillo S,Amoroso S,Magi S

更新日期：2017-10-12 00:00:00

abstract：:Targeting myeloid differentiation protein 2 (MD-2) or Toll-like receptor 4 (TLR4) with small molecule inhibitor rescues the systemic inflammatory response syndrome (SIRS) in sepsis due to infection with Gram-negative bacteria but not other microbes. Herein, we provided IκB kinase β (IKKβ) in innate immune process as a...

journal_title：Scientific reports

authors： Choi JH,Park SH,Jung JK,Cho WJ,Ahn B,Yun CY,Choi YP,Yeo JH,Lee H,Hong JT,Han SB,Kim Y

更新日期：2017-02-01 00:00:00

abstract：:The dynamics of networks of neuronal cultures has been recently shown to be strongly dependent on the network geometry and in particular on their dimensionality. However, this phenomenon has been so far mostly unexplored from the theoretical point of view. Here we reveal the rich interplay between network geometry and...

journal_title：Scientific reports

authors： Millán AP,Torres JJ,Bianconi G

更新日期：2018-07-02 00:00:00

abstract：:Sensing infrared radiation is done inexpensively with pyroelectric detectors that generate a temporary voltage when they are heated by the incident infrared radiation. Unfortunately the performance of these detectors deteriorates for longer wavelengths, leaving the detection of, for instance, millimetre-wave radiation...

journal_title：Scientific reports

authors： Kuznetsov SA,Paulish AG,Navarro-Cía M,Arzhannikov AV

更新日期：2016-02-16 00:00:00

abstract：:High abundance and widespread distribution of the archaeal phylum Bathyarchaeota in marine environment have been recognized recently, but knowledge about Bathyarchaeota in terrestrial settings and their correlation with environmental parameters is fairly limited. Here we reported the abundance of Bathyarchaeota member...

journal_title：Scientific reports

authors： Xiang X,Wang R,Wang H,Gong L,Man B,Xu Y

更新日期：2017-03-21 00:00:00

abstract：:The ability to induce reversible phase transitions between homogeneous solutions and biphasic liquid-liquid systems, at pre-defined and suitable operating temperatures, is of crucial relevance in the design of separation processes. Ionic-liquid-based aqueous biphasic systems (IL-based ABS) have demonstrated superior p...

journal_title：Scientific reports

authors： Passos H,Luís A,Coutinho JA,Freire MG

更新日期：2016-02-04 00:00:00

abstract：:Plant litter is an important component in wetland ecosystems, and the role of plant litter decomposition is considered to be important for wetland ecosystem functions and services. However, the consequences of litter inputs have seldom been experimentally tested in real ecosystems such as constructed wetlands (CWs). T...

journal_title：Scientific reports

authors： Ping Y,Pan X,Li W,Wang J,Cui L

更新日期：2019-09-25 00:00:00

abstract：:The Middle East is one of the most water stressed regions in the world, receiving the majority of its hydrological input during the winter, in the form of highly variable and scattered precipitation. The persistence of wintertime anticyclonic conditions over the region can deflect storm tracks and result in extended s...

journal_title：Scientific reports

authors： Kumar KN,Molini A,Ouarda TBMJ,Rajeevan MN

更新日期：2017-09-26 00:00:00

abstract：:The search for green and sustainable modification method to produce durable bamboo materials remains a challenge in industry. Here, heat treatment in tung oil at 100-200 °C was employed to modify bamboo materials. Oil permeation and distribution in the structure of bamboo samples during heat treatment were explored. T...

journal_title：Scientific reports

authors： Tang T,Zhang B,Liu X,Wang W,Chen X,Fei B

更新日期：2019-09-06 00:00:00

abstract：:We have employed a model system, inspired by SNARE proteins, to facilitate membrane fusion between Giant Unilamellar Vesicles (GUVs) and Large Unilamellar Vesicles (LUVs) under physiological conditions. In this system, two synthetic lipopeptide constructs comprising the coiled-coil heterodimer-forming peptides K4, (KI...

journal_title：Scientific reports

authors： Mora NL,Boyle AL,Kolck BJV,Rossen A,Pokorná Š,Koukalová A,Šachl R,Hof M,Kros A

更新日期：2020-02-20 00:00:00

abstract：:Interactions and coordination between conspecific individuals have produced a remarkable variety of collective behaviours. This co-operation occurs in vertebrate and invertebrate animals and is well expressed in the group flight of birds, fish shoals and highly organized activities of social insects. How individuals i...

journal_title：Scientific reports

authors： Vannier J,Vidal M,Marchant R,El Hariri K,Kouraiss K,Pittet B,El Albani A,Mazurier A,Martin E

更新日期：2019-10-17 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Xiao G,Zhao L,Huang Q,Yang J,Du H,Guo D,Xia M,Li G,Chen Z,Wang D

更新日期：2018-10-18 00:00:00

abstract：:Agricultural irrigation in the middle reaches of the Heihe River Basin consumes approximately 80% of the total river water. Whether the irrigation depth matches the water uptake depth of crops is one of the most important factors affecting the efficiency of irrigation water use. Our results indicated that the influenc...

journal_title：Scientific reports

authors： Yang B,Wen X,Sun X

更新日期：2015-10-14 00:00:00

abstract：:The state of preservation of wood in two samples from the Hanson Logboat, currently on display in Derby Museum and Art Gallery, was analysed using elemental analysis (EA), pyrolysis-gas chromatography/flame ionisation detection (Py-GC/FID), pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) and scanning electro...

journal_title：Scientific reports

authors： Pinder AP,Panter I,Abbott GD,Keely BJ

更新日期：2017-10-20 00:00:00

abstract：:Cancer cells accumulate somatic mutations as result of DNA damage, inaccurate repair and other mechanisms. Different genetic instability processes result in characteristic non-random patterns of DNA mutations, also known as mutational signatures. We developed mutSignatures, an integrated R-based computational framewor...

journal_title：Scientific reports

authors： Fantini D,Vidimar V,Yu Y,Condello S,Meeks JJ

更新日期：2020-10-26 00:00:00

abstract：:The complex phase transitions of vanadium dioxide (VO2) have drawn continual attention for more than five decades. Dynamically, ultrafast electron diffraction (UED) with atomic-scale spatiotemporal resolution has been employed to study the reaction pathway in the photoinduced transition of VO2, using bulk and strain-f...

journal_title：Scientific reports

authors： He X,Punpongjareorn N,Liang W,Lin Y,Chen C,Jacobson AJ,Yang DS

更新日期：2017-08-30 00:00:00

abstract：:A cDNA library from a pool of all the seven silk glands from a tropical spider species was constructed. More than 1000 expressed sequence tag (EST) clones were created. Almost 65% of the EST clones were identified and around 50% were annotated. The cellular and functional distribution of the EST clones indicated high ...

journal_title：Scientific reports

authors： Huang W,Zhang Y,Chen Y,Wang Y,Yuan W,Zhang N,Lam TJ,Gong Z,Yang D,Lin Z

更新日期：2017-10-17 00:00:00

abstract：:The prion protein (PrP) evolved from the subbranch of ZIP metal ion transporters comprising ZIPs 5, 6 and 10, raising the prospect that the study of these ZIPs may reveal insights relevant for understanding the function of PrP. Building on data which suggested PrP and ZIP6 are critical during epithelial-to-mesenchymal...

journal_title：Scientific reports

authors： Brethour D,Mehrabian M,Williams D,Wang X,Ghodrati F,Ehsani S,Rubie EA,Woodgett JR,Sevalle J,Xi Z,Rogaeva E,Schmitt-Ulms G

更新日期：2017-01-18 00:00:00

abstract：:Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in extracellular matri...

journal_title：Scientific reports

authors： Wang J,Chen L,Chen B,Meliton A,Liu SQ,Shi Y,Liu T,Deb DK,Solway J,Li YC

更新日期：2015-10-23 00:00:00

abstract：:Mid-infrared spectroscopy is of great importance in many areas and its integration with thin-film technology can economically enrich the functionalities of many existing devices. In this paper we propose a graphene-based ultra-compact spectrometer (several micrometers in size) that is compatible with complementary met...

journal_title：Scientific reports

authors： Wang X,Chen C,Pan L,Wang J

更新日期：2016-08-30 00:00:00

abstract：:Respiratory tract infections (RTIs) are common among Hajj pilgrims, but risk factors for RTIs and respiratory pathogen acquisition during the Hajj are not clearly identified. Based on previous studies, most frequent pathogens acquired by Hajj pilgrims were investigated: rhinovirus, human coronaviruses, influenza virus...

journal_title：Scientific reports

authors： Hoang VT,Ali-Salem S,Belhouchat K,Meftah M,Sow D,Dao TL,Ly TDA,Drali T,Ninove L,Yezli S,Alotaibi B,Raoult D,Parola P,Pommier de Santi V,Gautret P

更新日期：2019-11-28 00:00:00

abstract：:Alzheimer's disease is a debilitating neurodegenerative condition that progressively causes synaptic loss and major neuronal damage. Immunotherapy utilising Aβ as an active immunogen or via passive treatment utilising antibodies raised to amyloid have shown therapeutic promise. The migratory properties of peripheral b...

journal_title：Scientific reports

authors： Mold M,Kumar M,Mirza A,Shardlow E,Exley C

更新日期：2018-02-05 00:00:00

abstract：:Amyloid precursor protein (APP) intracellular domain (AICD) is a product of APP processing with transcriptional modulation activity, whose overexpression causes various Alzheimer's disease (AD)-related dysfunctions. Here we report that 1-(3',4'-dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid) (CHF50...

journal_title：Scientific reports

authors： Branca C,Sarnico I,Ruotolo R,Lanzillotta A,Viscomi AR,Benarese M,Porrini V,Lorenzini L,Calzà L,Imbimbo BP,Ottonello S,Pizzi M

更新日期：2014-04-09 00:00:00

abstract：:Heavy metals are environmental pollutants affect the integrity and distribution of living organisms in the ecosystem and also humans across the food chain. The study targeted the removal of copper (Cu2+) from aqueous solutions, depending on the biosorption process. The bacterial candidate was identified using 16S rRNA...

journal_title：Scientific reports

authors： Ghoniem AA,El-Naggar NE,Saber WIA,El-Hersh MS,El-Khateeb AY

更新日期：2020-06-11 00:00:00