Integrated Proteomic and Metabolomic prediction of Term Preeclampsia.

abstract：:Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors. One major obstacle is the blood-brain barrier (BBB), which hinders efficient passage of tumor biomarkers into the peripheral circulation. The ob...

journal_title：Scientific reports

authors： Zhu L,Cheng G,Ye D,Nazeri A,Yue Y,Liu W,Wang X,Dunn GP,Petti AA,Leuthardt EC,Chen H

更新日期：2018-04-26 00:00:00

abstract：:Solid oxide fuel cells (SOFCs) are promising electrochemical devices that enable the highest fuel-to-electricity conversion efficiencies under high operating temperatures. The concept of multi-stage electrochemical oxidation using SOFCs has been proposed and studied over the past several decades for further improving ...

journal_title：Scientific reports

authors： Matsuzaki Y,Tachikawa Y,Somekawa T,Hatae T,Matsumoto H,Taniguchi S,Sasaki K

更新日期：2015-07-28 00:00:00

abstract：:Quantitative magnetic resonance imaging (qMRI) is a versatile, non-destructive and non-invasive tool in life, material, and medical sciences. When multiple components contribute to the signal in a single pixel, however, it is difficult to quantify their individual contributions and characteristic parameters. Here we i...

journal_title：Scientific reports

authors： Vergeldt FJ,Prusova A,Fereidouni F,Amerongen HV,Van As H,Scheenen TWJ,Bader AN

更新日期：2017-04-13 00:00:00

abstract：:This study investigates magnetic ordering temperature in nano- and mesoscale structural features in an iron arsenide. Although magnetic ground states in quantum materials can be theoretically predicted from known crystal structures and chemical compositions, the ordering temperature is harder to pinpoint due to potent...

journal_title：Scientific reports

authors： Sefat AS,Wang XP,Liu Y,Zou Q,Fu M,Gai Z,Ganesan K,Vohra Y,Li L,Parker DS

更新日期：2019-12-27 00:00:00

abstract：:All solid-state lithium-ion transistors are considered as promising synaptic devices for building artificial neural networks for neuromorphic computing. However, the slow ionic conduction in existing electrolytes hinders the performance of lithium-ion-based synaptic transistors. In this study, we systematically explor...

journal_title：Scientific reports

authors： Nikam RD,Kwak M,Lee J,Rajput KG,Banerjee W,Hwang H

更新日期：2019-12-11 00:00:00

abstract：:Rice paddies are a major source of anthropogenic nitrous oxide (N2O) emissions, especially under alternate wetting-drying irrigation and high N input. Increasing photosynthate allocation to the grain in rice (Oryza sativa L.) has been identified as an effective strategy of genetic and agronomic innovation for yield en...

journal_title：Scientific reports

authors： Jiang Y,Huang X,Zhang X,Zhang X,Zhang Y,Zheng C,Deng A,Zhang J,Wu L,Hu S,Zhang W

更新日期：2016-07-05 00:00:00

abstract：:Knowledge of the genomic variation among different strains of a pathogenic microbial species can help in selecting optimal candidates for diagnostic assays and vaccine development. Pooled sequencing (Pool-seq) is a cost effective approach for population level genetic studies that require large numbers of samples such ...

journal_title：Scientific reports

authors： Weldatsadik RG,Wang J,Puhakainen K,Jiao H,Jalava J,Räisänen K,Datta N,Skoog T,Vuopio J,Jokiranta TS,Kere J

更新日期：2017-03-31 00:00:00

abstract：:Materials and construction methods of nests vary between bird species and at present, very little is known about the relationships between architecture and function in these structures. This study combines computational and experimental techniques to study the structural biology of nests fabricated by the edible nest ...

journal_title：Scientific reports

authors： Jessel HR,Chen S,Osovski S,Efroni S,Rittel D,Bachelet I

更新日期：2019-03-18 00:00:00

abstract：:DNA focused panel sequencing has been rapidly adopted to assess therapeutic targets in advanced/refractory cancer. Integrated Genomic Profiling (IGP) utilising DNA/RNA with tumour/normal comparisons in a Clinical Laboratory Improvement Amendments (CLIA) compliant setting enables a single assay to provide: therapeutic ...

journal_title：Scientific reports

authors： Borad MJ,Egan JB,Condjella RM,Liang WS,Fonseca R,Ritacca NR,McCullough AE,Barrett MT,Hunt KS,Champion MD,Patel MD,Young SW,Silva AC,Ho TH,Halfdanarson TR,McWilliams RR,Lazaridis KN,Ramanathan RK,Baker A,Aldrich J,

更新日期：2016-12-23 00:00:00

abstract：:Geographical variation of diabetic emergencies attended by prehospital emergency medical services (EMS) and the relationship between area-level social and demographic factors and risk of a diabetic emergency were examined. All cases of hypoglycaemia and hyperglycaemia attended by Ambulance Victoria between 1/01/2009 a...

journal_title：Scientific reports

authors： Villani M,Earnest A,Smith K,de Courten B,Zoungas S

更新日期：2018-03-23 00:00:00

abstract：:To better understand the brain function based on neural activity, a minimally invasive analysis technology in a freely moving animal is necessary. Such technology would provide new knowledge in neuroscience and contribute to regenerative medical techniques and prosthetics care. An application that combines optogenetic...

journal_title：Scientific reports

authors： Kobayashi T,Haruta M,Sasagawa K,Matsumata M,Eizumi K,Kitsumoto C,Motoyama M,Maezawa Y,Ohta Y,Noda T,Tokuda T,Ishikawa Y,Ohta J

更新日期：2016-02-16 00:00:00

abstract：:A better understanding of functional changes in the intervertebral disc (IVD) and interaction with endplate is essential to elucidate the pathogenesis of IVD degeneration disease (IDDD). To date, the simultaneous depiction of 3D micro-architectural changes of endplate with aging and interaction with IVD remains a tech...

journal_title：Scientific reports

authors： Cao Y,Liao S,Zeng H,Ni S,Tintani F,Hao Y,Wang L,Wu T,Lu H,Duan C,Hu J

更新日期：2017-03-07 00:00:00

abstract：:The NOON state, and its experimental approximation the Holland-Burnett state, have important applications in phase sensing measurement with enhanced sensitivity. However, most of the previous Holland-Burnett state interference (HBSI) experiments only investigated the area of the interference pattern in the region imme...

journal_title：Scientific reports

authors： Jin RB,Fujiwara M,Shimizu R,Collins RJ,Buller GS,Yamashita T,Miki S,Terai H,Takeoka M,Sasaki M

更新日期：2016-11-14 00:00:00

abstract：:The TREX complex mediates the passage of bulk cellular mRNA export to the nuclear export factor TAP/NXF1 via the export adaptors ALYREF or UIF, which appear to act in a redundant manner. TREX complex recruitment to nascent RNA is coupled with 5' capping, splicing and polyadenylation. Therefore to facilitate expression...

journal_title：Scientific reports

authors： Tunnicliffe RB,Tian X,Storer J,Sandri-Goldin RM,Golovanov AP

更新日期：2018-10-09 00:00:00

abstract：:The structural and magnetic properties of seven CeMn2Ge(2-x)Six compounds with x = 0.0-2.0 have been investigated in detail. Substitution of Ge with Si leads to a monotonic decrease of both a and c along with concomitant contraction of the unit cell volume and significant modifications of the magnetic states - a cross...

journal_title：Scientific reports

authors： Md Din MF,Wang JL,Cheng ZX,Dou SX,Kennedy SJ,Avdeev M,Campbell SJ

更新日期：2015-06-19 00:00:00

abstract：:L-asparaginase is a chemotherapy drug used to treat acute lymphoblastic leukemia (ALL). The main prerequisite for clinical efficacy of L-asparaginases is micromolar KM for asparagine to allow for complete depletion of this amino acid in the blood. Since currently approved L-asparaginases are of bacterial origin, immun...

journal_title：Scientific reports

authors： Rigouin C,Nguyen HA,Schalk AM,Lavie A

更新日期：2017-08-31 00:00:00

abstract：:Both disc hemorrhages (DH) and focal lamina cribrosa (LC) defects are recently considered as a progression factor in glaucoma. However, the clinical relevance of the presence of LC findings at the site of the DH has not yet been determined. We conducted a prospective study enrolling a total of 98 glaucoma eyes with DH...

journal_title：Scientific reports

authors： Park HL,Lee J,Jung Y,Park CK

更新日期：2017-06-14 00:00:00

abstract：:A classical model for social-influence-driven opinion change is the threshold model. Here we study cascades of opinion change driven by threshold model dynamics in the case where multiple initiators trigger the cascade, and where all nodes possess the same adoption threshold ϕ. Specifically, using empirical and styliz...

journal_title：Scientific reports

authors： Singh P,Sreenivasan S,Szymanski BK,Korniss G

更新日期：2013-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is a neurodegenerative autoimmune disease, where chronic inflammation plays an essential role in its pathology. A feature of MS is the production of autoantibodies stimulated by an altered-peptide-ligand response and epitope spreading, resulting in loss of tolerance for self-proteins. The invol...

journal_title：Scientific reports

authors： Mørkholt AS,Kastaniegaard K,Trabjerg MS,Gopalasingam G,Niganze W,Larsen A,Stensballe A,Nielsen S,Nieland JD

更新日期：2018-05-04 00:00:00

abstract：:Savant syndrome is a phenomenon whereby individuals with cognitive impairments have one or more outstanding abilities, inconsistent with their general intellectual functioning. Approximately 50% of savant individuals have autism spectrum disorder (ASD), and 10-30% of people with ASD have savant skills. To shed additio...

journal_title：Scientific reports

authors： Daniel E,Menashe I

更新日期：2020-02-10 00:00:00

abstract：:The current study aims to evaluate the burden of disease in Singapore by estimating the quality-adjusted life years (QALYs) lost due to mental disorders and chronic physical conditions. The second Singapore Mental Health Study (SMHS-2016) was conducted in 2016 among 6126 respondents aged 18 years and above. The World ...

journal_title：Scientific reports

authors： Abdin E,Chong SA,Vaingankar JA,Shafie S,Verma S,Luo N,Tan KB,James L,Heng D,Subramaniam M

更新日期：2020-02-14 00:00:00

abstract：:X-ray phase-contrast imaging (XPCI) can dramatically improve soft tissue contrast in X-ray medical imaging. Despite worldwide efforts to develop novel XPCI systems, a numerical framework to rigorously predict the performance of a clinical XPCI system at a human scale is not yet available. We have developed such a tool...

journal_title：Scientific reports

authors： Sung Y,Segars WP,Pan A,Ando M,Sheppard CJ,Gupta R

更新日期：2015-07-14 00:00:00

abstract：:Measurement-based quantum computing is one of the most promising quantum computing models. Although various universal resource states have been proposed so far, it was open whether only two Pauli bases are enough for both of universal measurement-based quantum computing and its verification. In this paper, we construc...

journal_title：Scientific reports

authors： Takeuchi Y,Morimae T,Hayashi M

更新日期：2019-09-19 00:00:00

abstract：:The majority of colorectal cancer (CRC) arises from precursor lesions known as polyps. The molecular determinants that distinguish benign from malignant polyps remain unclear. To molecularly characterize polyps, we utilized Cancer Adjacent Polyp (CAP) and Cancer Free Polyp (CFP) patients. CAPs had tissues from the res...

journal_title：Scientific reports

authors： Druliner BR,Wang P,Bae T,Baheti S,Slettedahl S,Mahoney D,Vasmatzis N,Xu H,Kim M,Bockol M,O'Brien D,Grill D,Warner N,Munoz-Gomez M,Kossick K,Johnson R,Mouchli M,Felmlee-Devine D,Washechek-Aletto J,Smyrk T,Oberg A,

更新日期：2018-02-16 00:00:00

abstract：:A lack of information regarding whether genetic polymorphisms of SLCO1B1 and ABCG2 affect the pharmacokinetics (PKs)/pharmacodynamics (PDs) of rosuvastatin in elderly subjects prevents optimal individualized pharmacotherapy of rosuvastatin in clinical settings. This study aimed to investigate the effect of age and gen...

journal_title：Scientific reports

authors： Kim Y,Yoon S,Choi Y,Yoon SH,Cho JY,Jang IJ,Yu KS,Chung JY

更新日期：2019-12-19 00:00:00

abstract：:We propose a novel injection scheme for laser-driven wakefield acceleration in which controllable localized electron injection is obtained by inserting nanoparticles into a plasma medium. The nanoparticles provide a very confined electric field that triggers localized electron injection where nonlinear plasma waves ar...

journal_title：Scientific reports

authors： Cho MH,Pathak VB,Kim HT,Nam CH

更新日期：2018-11-16 00:00:00

abstract：:Randomizing the layer thickness of superlattices (SL) can lead to localization of coherent phonons and thereby reduces the lattice thermal conductivity κ l . In this work, we propose strategies that can suppress incoherent phonon transport in the above random multilayer (RML) structure to further reduce κ l . Molecula...

journal_title：Scientific reports

authors： Chakraborty P,Cao L,Wang Y

更新日期：2017-08-15 00:00:00

abstract：:We show a new resonance acceleration scheme for generating ultradense relativistic electron bunches in helical motions and hence emitting brilliant vortical γ-ray pulses in the quantum electrodynamic (QED) regime of circularly-polarized (CP) laser-plasma interactions. Here the combined effects of the radiation reactio...

journal_title：Scientific reports

authors： Chang HX,Qiao B,Huang TW,Xu Z,Zhou CT,Gu YQ,Yan XQ,Zepf M,He XT

更新日期：2017-03-24 00:00:00

abstract：:Transgenic sheep can be used to achieve genetic improvements in breeds and as an important large-animal model for biomedical research. In this study, we generated a TALEN plasmid specific for ovine MSTN and transfected it into fetal fibroblast cells of STH sheep. MSTN biallelic-KO somatic cells were selected as nuclea...

journal_title：Scientific reports

authors： Li H,Wang G,Hao Z,Zhang G,Qing Y,Liu S,Qing L,Pan W,Chen L,Liu G,Zhao R,Jia B,Zeng L,Guo J,Zhao L,Zhao H,Lv C,Xu K,Cheng W,Li H,Zhao HY,Wang W,Wei HJ

更新日期：2016-09-22 00:00:00

abstract：:IL-37 is a novel pro-angiogenic cytokine that potently promotes endothelial cell activation and pathological angiogenesis in our previous study, but the mechanisms behind the pro-angiogenic effect of IL-37 are less well understood. Extending our observations, we found that TGF-β interacts with IL-37, and potently enha...

journal_title：Scientific reports

authors： Zhao M,Hu Y,Jin J,Yu Y,Zhang S,Cao J,Zhai Y,Wei R,Shou J,Cai W,Liu S,Yang X,Xu GT,Yang J,Corry DB,Su SB,Liu X,Yang T

更新日期：2017-07-21 00:00:00