Focused Ultrasound-enabled Brain Tumor Liquid Biopsy.

abstract：:The white spot syndrome virus (WSSV) causes mass mortalities in the aquaculture of shrimps worldwide. The mud shrimp Austinogebia edulis (Ngoc-Ho & Chan, 1992) is an economically important sea food item occurring along the west coast of Taiwan. While the population of A. edulis began to decrease with some fluctuations...

journal_title：Scientific reports

authors： Zhu F,Twan WH,Tseng LC,Peng SH,Hwang JS

更新日期：2019-12-09 00:00:00

abstract：:Supercontinuum generation in Kerr media has become a staple of nonlinear optics. It has been celebrated for advancing the understanding of soliton propagation as well as its many applications in a broad range of fields. Coherent spectral broadening of laser light is now commonly performed in laboratories and used in c...

journal_title：Scientific reports

authors： Ciret C,Gorza SP,Husko C,Roelkens G,Kuyken B,Leo F

更新日期：2018-11-21 00:00:00

abstract：:Free-surface vortices have long been studied to develop an understanding of similar rotating flow phenomena observed in nature and technology. However, a complete description of its turbulent three-dimensional flow field still remains elusive. In contrast, the related Taylor-Couette flow system has been well explicate...

journal_title：Scientific reports

authors： Mulligan S,De Cesare G,Casserly J,Sherlock R

更新日期：2018-01-16 00:00:00

abstract：:Expression of various molecules on the surface of cancer cells compared to normal cells creates a platform for the generation of various drug vehicles for targeted therapy. Multiple interactions between ligands and their receptors mediated by targeting peptide-modified polymer could enable simultaneous delivery of a d...

journal_title：Scientific reports

authors： Sarangthem V,Cho EA,Yi A,Kim SK,Lee BH,Park RW

更新日期：2018-03-01 00:00:00

abstract：:People with normal hearing thresholds can nonetheless have difficulty with understanding speech in noisy backgrounds. The origins of such supra-threshold hearing deficits remain largely unclear. Previously we showed that the auditory brainstem response to running speech is modulated by selective attention, evidencing ...

journal_title：Scientific reports

authors： Saiz-Alía M,Forte AE,Reichenbach T

更新日期：2019-10-01 00:00:00

abstract：:Plant-based proteins are increasingly being used in aquafeeds, but one of the limitations is taurine deficiency that can be especially detrimental for carnivorous fish. In this study, taurine supplementation in high plant protein diets (low fish meal, 15%) was investigated on the growth performance and fillet organole...

journal_title：Scientific reports

authors： Kotzamanis Y,Tsironi T,Brezas A,Grigorakis K,Ilia V,Vatsos I,Romano N,van Eys J,Kumar V

更新日期：2020-07-23 00:00:00

abstract：:Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae, a well-known Chinese medicinal herb that presents anticancer effects in various types of cancer cell lines. In this study, we have successfully established zebrafish xenografts with 5 various human cancer cell lines; and validated these models with ant...

journal_title：Scientific reports

authors： Zhu XY,Guo DW,Lao QC,Xu YQ,Meng ZK,Xia B,Yang H,Li CQ,Li P

更新日期：2019-03-14 00:00:00

abstract：:Accumulating evidence supports the polygenic nature of most complex diseases, suggesting the involvement of many susceptibility genes with small effect sizes. Although hundreds of genes may underlie the genetic architecture of complex diseases, those involved in a given disease are probably not randomly distributed, b...

journal_title：Scientific reports

authors： Liu X,Yu P,Cheng C,Potash JB,Han S

更新日期：2016-09-14 00:00:00

abstract：:Little is known about the effects of posterior tethers on the development of proximal junctional kyphosis (PJK). We evaluated the ability of posterior tethers to the proximal motion segment stiffness in long instrumented spinal instrumentation and fusion using a whole body human FE model. A series of finite element (F...

journal_title：Scientific reports

authors： Yagi M,Nakahira Y,Watanabe K,Nakamura M,Matsumoto M,Iwamoto M

更新日期：2020-02-26 00:00:00

abstract：:Predicting function-related amino acids in proteins with unknown function or unknown allosteric binding sites in drug-targeted proteins is a task of paramount importance in molecular biomedicine. In this paper we introduce a simple, light and computationally inexpensive structure-based method to identify catalytic sit...

journal_title：Scientific reports

authors： Aubailly S,Piazza F

更新日期：2015-10-08 00:00:00

abstract：:We report studies of [Formula: see text]-dependent Landé g-factor, performed by both continuous media approximation [Formula: see text] method, and atomistic tight-binding [Formula: see text] approach. We propose an effective, mesoscopic model for InAs that we are able to successfully compare with atomistic calculatio...

journal_title：Scientific reports

authors： Gawarecki K,Zieliński M

更新日期：2020-12-15 00:00:00

abstract：:Solid oxide fuel cells (SOFCs) are promising electrochemical devices that enable the highest fuel-to-electricity conversion efficiencies under high operating temperatures. The concept of multi-stage electrochemical oxidation using SOFCs has been proposed and studied over the past several decades for further improving ...

journal_title：Scientific reports

authors： Matsuzaki Y,Tachikawa Y,Somekawa T,Hatae T,Matsumoto H,Taniguchi S,Sasaki K

更新日期：2015-07-28 00:00:00

abstract：:Nine new bicyclic cembranoids, sarcophytrols M-U(1-9), were isolated from the South China Sea soft coral Sarcophyton trocheliophorum as minor components, along with one known related cembranoid 10. Their structures were elucidated by detailed spectroscopic analysis and chemical conversion. The chemical structures of t...

journal_title：Scientific reports

authors： Liang LF,Chen WT,Li XW,Wang HY,Guo YW

更新日期：2017-04-21 00:00:00

abstract：:Preclinical studies show that the dopamine D3 receptor (D3R) is involved in the reinstatement of drug seeking and motivation for drugs of abuse. A D3R gene variant, Ser9Gly (rs6280) has been linked to nicotine dependence, yet the mechanisms underlying its involvement in nicotine dependence is unclear. This study inves...

journal_title：Scientific reports

authors： Chukwueke CC,Kowalczyk WJ,Di Ciano P,Gendy M,Taylor R,Heishman SJ,Le Foll B

更新日期：2020-03-05 00:00:00

abstract：:We measured the magnitude of submarine fresh groundwater discharge (SFGD) and associated nutrient inputs to Jocheon harbor, on Jeju Island, Korea, during four sampling periods, in order to determine the link between SFGD and Ulva sp. green tide development. Good correlations among salinity, 222Rn, and dissolved inorga...

journal_title：Scientific reports

authors： Kwon HK,Kang H,Oh YH,Park SR,Kim G

更新日期：2017-07-24 00:00:00

abstract：:Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical ...

journal_title：Scientific reports

authors： Li J,Fejes P,Lorenser D,Quirk BC,Noble PB,Kirk RW,Orth A,Wood FM,Gibson BC,Sampson DD,McLaughlin RA

更新日期：2018-10-04 00:00:00

abstract：:Trastuzumab combined with chemotherapy is standard of care for HER2 positive advanced gastro-esophageal cancers. The reported prevalence of HER2 discordance between primary tumors and corresponding metastases varies, hampering uniform patient selection for HER2 targeted therapy. This meta-analysis explores the influen...

journal_title：Scientific reports

authors： Creemers A,Ter Veer E,de Waal L,Lodder P,Hooijer GKJ,van Grieken NCT,Bijlsma MF,Meijer SL,van Oijen MGH,van Laarhoven HWM

更新日期：2017-06-09 00:00:00

abstract：:Contact heat evoked potentials (CHEPs) have become an acknowledged research tool in the assessment of the integrity of the nociceptive system and gained importance in the diagnostic work-up of patients with suspected small fiber neuropathy. For the latter, normative values for CHEP amplitude and latency are indispensa...

journal_title：Scientific reports

authors： Rosner J,Hostettler P,Scheuren PS,Sirucek L,Rinert J,Curt A,Kramer JLK,Jutzeler CR,Hubli M

更新日期：2018-07-20 00:00:00

abstract：:Phase modulators are one of the key components of many applications in electromagnetic and opto-electric wave propagations. Phase-shifters play an integral role in communications, imaging and in coherent material excitations. In order to realize the terahertz (THz) electromagnetic spectrum as a fully-functional bandwi...

journal_title：Scientific reports

authors： Dutta M,Betal S,Peralta XG,Bhalla AS,Guo R

更新日期：2016-11-30 00:00:00

abstract：:Previous reports suggest that offspring of mothers who smoke during pregnancy have greater risk of developing depression. However, it is unclear whether this is due to intrauterine effects. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC) from the UK (N = 2,869), the Nord-Trøndelag health s...

journal_title：Scientific reports

authors： Taylor AE,Carslake D,de Mola CL,Rydell M,Nilsen TIL,Bjørngaard JH,Horta BL,Pearson R,Rai D,Galanti MR,Barros FC,Romundstad PR,Davey Smith G,Munafò MR

更新日期：2017-10-03 00:00:00

abstract：:This study aims to evaluate the necessity of urgent neuroimaging for emergency admissions exhibiting symptomatology of profound hyponatremia. We retrospectively analyzed the medical records of all patients admitted to the emergency room of the University Hospital Münster from 2010 to 2014 with a serum sodium value < 1...

journal_title：Scientific reports

authors： Bokemeyer A,Dziewas R,Wiendl H,Schwindt W,Bicsán P,Kümpers P,Pavenstädt H

更新日期：2017-05-16 00:00:00

abstract：:Malignant transformation results in increased levels of reactive oxygen species (ROS). Adaption to this toxic stress allows cancer cells to proliferate. Recently, piperlongumine (PL), a natural alkaloid, was identified to exhibit novel anticancer effects by targeting ROS signaling. PL induces apoptosis specifically in...

journal_title：Scientific reports

authors： Li J,Sharkey CC,King MR

更新日期：2015-05-18 00:00:00

abstract：:Dramatic functional changes of enzyme usually require scores of alterations in amino acid sequence. However, in the case of guanylate kinase (GK), the functional novelty is induced by a single (S→P) mutation, leading to the functional transition of the enzyme from a phosphoryl transfer kinase into a phosphorprotein in...

journal_title：Scientific reports

authors： Zhang Y,Niu H,Li Y,Chu H,Shen H,Zhang D,Li G

更新日期：2015-02-12 00:00:00

abstract：:Psychological and behavioural interventions may be effective in reducing menopause-related symptoms. This randomized controlled trial aimed to evaluate the effectiveness of Mindfulness-based Stress Reduction (MBSR) in reducing menopause-related symptoms by comparing with an active control group, the menopause educatio...

journal_title：Scientific reports

authors： Wong C,Yip BH,Gao T,Lam KYY,Woo DMS,Yip ALK,Chin CY,Tang WPY,Choy MMT,Tsang KWK,Ho SC,Ma HSW,Wong SYS

更新日期：2018-04-26 00:00:00

abstract：:Glyoxalase pathway plays an important role in stress adaptation and many clinical disorders. The first enzyme of this pathway, glyoxalase I (GlxI), uses methylglyoxal as a substrate and requires either Ni(II)/Co(II) or Zn(II) for activity. Here we have investigated the origin of different metal ion specificities of Gl...

journal_title：Scientific reports

authors： Kaur C,Vishnoi A,Ariyadasa TU,Bhattacharya A,Singla-Pareek SL,Sopory SK

更新日期：2013-11-13 00:00:00

abstract：:Despite the fact that magnetic thrombolytic composites is an emerging area, all known so far systems are based on the similar mechanism of action: thrombolytic enzyme releases from the magnetic carrier leaving non-active matrix, thus making the whole system active only for a limited period of time. Such systems often ...

journal_title：Scientific reports

authors： Drozdov AS,Vinogradov VV,Dudanov IP,Vinogradov VV

更新日期：2016-06-20 00:00:00

abstract：:Solving the crystal structure of Cbl(TKB) in complex with a pentapeptide, pYTPEP, revealed that the PEP region adopted a poly-L-proline type II (PPII) helix. An unnatural amino acid termed a proline-templated glutamic acid (ptE) that constrained both the backbone and sidechain to the bound conformation was synthesized...

journal_title：Scientific reports

authors： Kumar EA,Chen Q,Kizhake S,Kolar C,Kang M,Chang CE,Borgstahl GE,Natarajan A

更新日期：2013-01-01 00:00:00

abstract：:The incidence of cancer in the United Kingdom has increased significantly over the last four decades. The aim of this study was to examine trends in UK cancer incidence and mortality by cancer site and assess the potential for overdiagnosis. Using Cancer Research UK incidence and mortality data for the period (1971-20...

journal_title：Scientific reports

authors： Oke JL,O'Sullivan JW,Perera R,Nicholson BD

更新日期：2018-10-02 00:00:00

abstract：:Predicting regions at risk from introductions of non-native species and the subsequent invasions is a fundamental aspect of horizon scanning activities that enable the development of more effective preventative actions and planning of management measures. The Asian cyprinid fish topmouth gudgeon Pseudorasbora parva ha...

journal_title：Scientific reports

authors： Fletcher DH,Gillingham PK,Britton JR,Blanchet S,Gozlan RE

更新日期：2016-05-20 00:00:00

abstract：:In this work, TiN film deposited by plasma enhanced atomic layer deposition (PEALD) is adopted to modify the commercial anatase TiO2 powders. A series of analyses indicate that the surface modification of 20, 50 and 100 cycles of TiN by PEALD does not change the morphology, crystal size, lattice parameters, and surfac...

journal_title：Scientific reports

authors： Cao YQ,Zhao XR,Chen J,Zhang W,Li M,Zhu L,Zhang XJ,Wu D,Li AD

更新日期：2018-08-14 00:00:00