Abstract：
:X-ray phase-contrast imaging (XPCI) can dramatically improve soft tissue contrast in X-ray medical imaging. Despite worldwide efforts to develop novel XPCI systems, a numerical framework to rigorously predict the performance of a clinical XPCI system at a human scale is not yet available. We have developed such a tool by combining a numerical anthropomorphic phantom defined with non-uniform rational B-splines (NURBS) and a wave optics-based simulator that can accurately capture the phase-contrast signal from a human-scaled numerical phantom. Using a synchrotron-based, high-performance XPCI system, we provide qualitative comparison between simulated and experimental images. Our tool can be used to simulate the performance of XPCI on various disease entities and compare proposed XPCI systems in an unbiased manner.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Sung Y,Segars WP,Pan A,Ando M,Sheppard CJ,Gupta Rdoi
10.1038/srep12011subject
Has Abstractpub_date
2015-07-14 00:00:00pages
12011issn
2045-2322pii
srep12011journal_volume
5pub_type
杂志文章abstract：:A peptide vaccine designed to induce T-cell immunity to telomerase, GV1001, has been shown to modulate cellular signaling pathways and confer a direct anti-cancer effect through the interaction with heat shock protein (HSP) 90 and 70. Here, we have found that GV1001 can modulate transactivation protein-mediated human ...
journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-07-01 00:00:00
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pub_type： 临床试验,杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2013-11-26 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18047-w
更新日期：2018-01-11 00:00:00
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pub_type： 杂志文章
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更新日期：2020-06-23 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-10-12 00:00:00
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更新日期：2018-10-02 00:00:00
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pub_type： 杂志文章
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更新日期：2018-11-09 00:00:00
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更新日期：2016-08-17 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-07-07 00:00:00
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pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 已发布勘误
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更新日期：2020-07-29 00:00:00
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pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-04-07 00:00:00
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pub_type： 杂志文章
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更新日期：2016-03-04 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2014-07-18 00:00:00
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pub_type： 杂志文章
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更新日期：2020-03-03 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-01-06 00:00:00
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