Abstract:
:Membrane fouling, i.e. accumulation of unwanted material on the surface of the membrane is a significant problem in filtration processes since it commonly degrades membrane performance and increases operating costs. Therefore, the advantages of early stage monitoring and control of fouling are widely recognized. In this work, the potential of using Raman spectroscopy coupled to chemometrics in order to quantify degree of membrane fouling in real-time was investigated. The Raman data set collected from adsorption experiments with varying pHs and concentrations of model compound vanillin was used to develop a predictive model based on principal component analysis (PCA) for the quantification of the vanillin adsorbed on the membrane. The correspondence between the predicted concentrations based on the PCA model and actual measured concentrations of adsorbed vanillin was moderately good. The model developed was successful in monitoring both adsorption and desorption processes. Furthermore, the model was able to detect abnormally proceeding experiment based on differentiating PCA score and loading values. The results indicated that the presented approach of using Raman spectroscopy combined with a PCA model has potential for use in monitoring and control of fouling and cleaning in membrane processes.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Virtanen T,Reinikainen SP,Lahti J,Mänttäri M,Kallioinen Mdoi
10.1038/s41598-018-29268-ysubject
Has Abstractpub_date
2018-07-23 00:00:00pages
11057issue
1issn
2045-2322pii
10.1038/s41598-018-29268-yjournal_volume
8pub_type
杂志文章abstract::Relocation of earthquakes recorded by the agency for meteorology, climatology and geophysics (BMKG) in Indonesia and inversions of global positioning system (GPS) data reveal clear seismic gaps to the south of the island of Java. These gaps may be related to potential sources of future megathrust earthquakes in the re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72142-z
更新日期:2020-09-17 00:00:00
abstract::Neuronal activity-dependent synaptic plasticity, a basis for learning and memory, is tightly correlated with the pattern of increase in intracellular Ca(2+) concentration ([Ca(2+)](i)). Here, using combined application of electrophysiological experiments and systems biological simulation, we show that such a correlati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00143
更新日期:2011-01-01 00:00:00
abstract::Superdirective antennas developed over the last century have received renewed interest in recent years from the development of metamaterials. These arrays of electromagnetic resonators (or meta-atoms) carrying short wavelength electro- and/or magneto-inductive waves support current distributions with very high spatial...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56988-6
更新日期:2020-01-14 00:00:00
abstract::In the last 40 years only one new antitubercular drug has been approved, whilst resistance to current drugs, including rifampicin, is spreading. Here, we used the model organism Mycobacterium smegmatis to study mechanisms of phenotypic mycobacterial resistance, employing quantitative mass spectrometry-based proteomics...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43858
更新日期:2017-03-06 00:00:00
abstract::In dentistry, the wet-bonding approach relies on water to maintain demineralized collagen expanded for proper resin infiltration; nevertheless, hydrolytic instability of the resin-dentin interface is inevitable with current bonding techniques. Considering dimethyl sulfoxide's (DMSO) ability to "biomodify" collagen and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34726-8
更新日期:2018-11-15 00:00:00
abstract::Environmental impacts from ecotourism and outdoor recreation activities on terrestrial and aquatic ecosystems are well-reported in the literature, but less is known regarding the impacts of outdoor environmental education activities. Student activity during stream classes may cause substrate disruption and localized i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38210-1
更新日期:2019-02-05 00:00:00
abstract::Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutations of SHP-2 have been foun...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06401-x
更新日期:2017-07-20 00:00:00
abstract::Enzyme replacement therapies have revolutionized patient treatment for multiple rare lysosomal storage diseases but show limited effectiveness for addressing pathologies in "hard-to-treat" organs and tissues including brain and bone. Here we investigate the plant lectin RTB as a novel carrier for human lysosomal enzym...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14144
更新日期:2015-09-18 00:00:00
abstract::Solid-state spin-based qubits offer good prospects for scaling based on their long coherence times and nexus to large-scale electronic scale-up technologies. However, high-threshold quantum error correction requires a two-dimensional qubit array operating in parallel, posing significant challenges in fabrication and c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13308-0
更新日期:2017-10-17 00:00:00
abstract::Most glioblastoma patients have a dismal prognosis, although some survive several years. However, only few biomarkers are available to predict the disease course. EGR1 and EGR3 have been linked to glioblastoma stemness and tumour progression, and this study aimed to investigate their spatial expression and prognostic ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66236-x
更新日期:2020-06-09 00:00:00
abstract::Abiotic emergence of ordered information stored in the form of RNA is an important unresolved problem concerning the origin of life. A polymer longer than 40-100 nucleotides is necessary to expect a self-replicating activity, but the formation of such a long polymer having a correct nucleotide sequence by random react...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58060-0
更新日期:2020-02-03 00:00:00
abstract::Interleukin 17 (IL-17) stimulates the osteogenic differentiation of progenitor cells in vitro through a synergy with bone morphogenetic protein (BMP)-2. This study investigates whether the diverse responses mediated by IL-17 in vivo also lead to enhanced BMP-2-induced bone formation. Since IL-17 is known to induce ost...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25564-9
更新日期:2018-05-08 00:00:00
abstract::Interference of two combined white light beams produces Newton colors if one of the beams is retarded relative to the other by from 400 nm to 2000 nm. In this case the corresponding interfering spectral components are added as two scalars at the beam combination. If the retardance is below 400 nm the two-beam interfer...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17340
更新日期:2015-11-27 00:00:00
abstract::Activation of TLR4 by lipopolysaccharide (LPS) induces both pro-inflammatory and anti-inflammatory cytokine production in macrophages. Type 4 phosphodiesterases (PDE4) are key cAMP-hydrolyzing enzymes, and PDE4 inhibitors are considered as immunosuppressors to various inflammatory responses. We demonstrate here that P...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46165
更新日期:2017-04-06 00:00:00
abstract::The use of engineered viral strains such as gene therapy vectors and oncolytic viruses (OV) to selectively destroy cancer cells is poised to make a major impact in the clinic and revolutionize cancer therapy. In particular, several studies have shown that OV therapy is safe and well tolerated in humans and can infect ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26786
更新日期:2016-05-26 00:00:00
abstract::Pond-dwelling cyclic parthenogens are often proposed to be highly vagile. However, the Holarctic biogeography of parthenogens has been hampered by very limited sampling in the eastern Palearctic. Here we examine the geographic boundaries, diversity, and connectivity across the Palearctic for the Daphnia curvirostris c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43281-9
更新日期:2019-05-02 00:00:00
abstract::The brain effortlessly recognizes objects even when the visual information belonging to an object is widely separated, as well demonstrated by the Kanizsa-type illusory contours (ICs), in which a contour is perceived despite the fragments of the contour being separated by gaps. Such large-range visual completion has l...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep08346
更新日期:2015-02-10 00:00:00
abstract::We aimed to investigate whether the newborns of mothers with maternal depression (MD) had lower vitamin D levels than newborns of non-MD (NMD) mothers and identify the potential mechanism underlying this association. Maternal depressive symptoms in late pregnancy and concentrations of cord blood 25 hydroxyvitamin D (2...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01778-1
更新日期:2017-05-08 00:00:00
abstract::Knowing when, where, and how seizures are initiated in large-scale epileptic brain networks remains a widely unsolved problem. Seizure precursors - changes in brain dynamics predictive of an impending seizure - can now be identified well ahead of clinical manifestations, but either the seizure onset zone or remote bra...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47092-w
更新日期:2019-07-23 00:00:00
abstract::The most common surgical emergency is suspected acute appendicitis, the lifetime risk of acute appendicitis is estimated to be 8.6% for men and 6.7% for women, with a male to female ratio of 1.4:1; correct diagnosis can be made in 70-80% of patients after the operations about 32% of appendectomies revealed normal appe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58847-1
更新日期:2020-02-06 00:00:00
abstract:BACKGROUND:Virtual reality (VR) has been shown to reduce pain, however outcome parameters of previous studies have primarily been of a subjective nature and susceptible to bias. This study investigated the effect of VR on cortical processing of evoked potentials (EPs) and subjectively reported pain. Additionally, we ex...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41598-020-66035-4
更新日期:2020-06-03 00:00:00
abstract::The slow-growing genus Bradyrhizobium is biologically important in soils, with different representatives found to perform a range of biochemical functions including photosynthesis, induction of root nodules and symbiotic nitrogen fixation and denitrification. Consequently, the role of the genus in soil ecology and bio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25858
更新日期:2016-05-10 00:00:00
abstract::In clinical translational research and molecular in vitro diagnostics, a major challenge in the detection of genetic mutations is overcoming artefactual results caused by the low-quality of formalin-fixed paraffin-embedded tissue (FFPET)-derived DNA (FFPET-DNA). Here, we propose the use of an 'internal quality control...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18642-x
更新日期:2018-01-11 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-24113-8
更新日期:2018-04-20 00:00:00
abstract::The tibial tuberosity-trochlear groove (TT-TG) distance is a radiographic measurement that is used to quantify malalignment of the patellofemoral joint (PFJ) in cross-sectional imaging. There is an ongoing debate about the impact of the TT-TG-distance on lateral patellar instability and the initiating of cartilage deg...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72299-7
更新日期:2020-09-18 00:00:00
abstract::Exolysin (ExlA) is a recently-identified pore-forming toxin secreted by a subset of Pseudomonas aeruginosa strains identified worldwide and devoid of Type III secretion system (T3SS), a major virulence factor. Here, we characterized at the ultrastructural level the lesions caused by an ExlA-secreting strain, CLJ1, in ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02349-0
更新日期:2017-05-18 00:00:00
abstract::Identification of different isomer structures of atomic and molecular clusters has long been a challenging task in the field of cluster science. Here we present a three-dimensional (3D) assignment method, combining the energy (1D) and simulated (2D) spectra to assure the assignment of the global minimum structure. Thi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17738
更新日期:2015-12-03 00:00:00
abstract::Academic research on dinoflagellate, the primary causative agent of harmful algal blooms (HABs), is often hindered by the coexistence with bacteria in laboratory cultures. The development of axenic dinoflagellate cultures is challenging and no universally accepted method suit for different algal species. In this study...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80638-x
更新日期:2021-01-08 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-42195-w
更新日期:2019-04-10 00:00:00
abstract::Bile acid (BA) signatures are altered in many disease states. BA metabolism is an important microbial function to assist gut colonization and persistence, as well as microbial survival during gastro intestinal (GI) transit and it is an important criteria for potential probiotic bacteria. Microbes that express bile sal...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58069-5
更新日期:2020-01-24 00:00:00