Two new triterpenes from the roots of Pfaffia glomerata.

Abstract:

:Pfaffia paniculata is a commercialized dietary supplement used as the substitute for the Asian ginseng in Brazil. We conducted the systematic isolation of the EtOAc fraction with anti-inflammatory effect and two new triterpenoids, along with 26 known compounds were characterized by means of MS and NMR analysis. Interestingly, the new compound 1 is the first seco-ring triterpenoid reported in the Pfaffia genus. Furthermore, among the known compounds, 14 and 15 exhibited anti-inflammatory activity in Caco-2 cells, but two new compounds showed no anti-inflammatory.

journal_name

J Asian Nat Prod Res

authors

Lian L,Feng Y,Li YW,Bei B,Tang YT,Wang H,Feng QM,Chen G

doi

10.1080/10286020.2018.1446949

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

442-448

issue

5

eissn

1028-6020

issn

1477-2213

journal_volume

21

pub_type

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