Two new p-coumaroylated sesquiterpenoids from Pilea cavaleriei.

Abstract:

:A new p-coumaroylated santalane-type sesquiterpenoid, 8-p-coumaroyl-α-santalene (1), a new p-coumaroylated oplopanane-type sesquiterpenoid, 8-β-p-coumaroyl-oplopanone (2), and three known p-coumaroylated humulene-type sesquiterpenoids (3-5) were isolated from the ethanol extract of the whole herbs of Pilea cavaleriei. Their structures were elucidated based on the combination of 1D and 2D NMR and HRMS methods. Compound 2 was found to show anti-tuberculosis activity with MIC of 16 μg/ml.

journal_name

J Asian Nat Prod Res

authors

Ren HC,Zhang J,Liang H

doi

10.1080/10286020.2017.1320990

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

109-116

issue

2

eissn

1028-6020

issn

1477-2213

journal_volume

20

pub_type

杂志文章
  • Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction.

    abstract::Pharmacochemistry and integrated pharmacokinetics of six alkaloids (groenlandicine, berberine, palmatine, epiberberine, jatrorrhizine, and columbamine) after oral administration of Huang-Lian-Jie-Du-Tang (HLJDT) decoction were investigated in this paper. The method of plasma pharmacochemistry was applied to predict th...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.913577

    authors: Ma ZT,Yang XW,Zhang Y,Liu JX

    更新日期:2014-01-01 00:00:00

  • Three new noroleanane-type triterpenes from the roots of Pfaffia glomerata.

    abstract::The Amaranthaceae plant, Pfaffia glomerata, which is so-called as Brazil ginseng, is widely distributed in South American countries. Three new noroleanane-type triterpenes and four known oleanane-type triterpenes were isolated from the roots of P. glomerata. Their structures were determined by spectroscopic methods in...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1343820

    authors: Han YZ,Zhou Y,Zhang ZT,Niu SY,Liu XH,Jia XY

    更新日期:2018-05-01 00:00:00

  • Two new steroidal saponins from Tribulus terrestris L.

    abstract::Two new steroidal saponins were isolated from the fruits of Tribulus terrestris L. Their structures were elucidated by spectroscopic and chemical analysis as (23S,24R,25R)-5alpha-spirostane-3beta,23,24-triol-3-O-{alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 4)]-beta-D-galactopyranoside} (1) and (23S...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020903405449

    authors: Liu T,Lu X,Wu B,Chen G,Hua HM,Pei YH

    更新日期:2010-01-01 00:00:00

  • Antioxidant compounds from ethanol extracts of bamboo (Neosinocalamus affinis) leaves.

    abstract::Activity-guided fractionation of Neosinocalamus affinis leaves led to obtain two new flavonoids, 4'-O-((7″R,8″S)-8″-guaiacylglyceryl)-pleioside B (9) and apigenin 6-C-β-d-fucopyranosyl-7-O-β-d-glucopyranoside (10) along with eight known compounds. Their structures were elucidated on the basis of spectroscopic data (UV...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.981164

    authors: Luo GY,Luo YG,Zhou R,Zhou M,Gu J,Ye Q,Dai Y,Zhang GL

    更新日期:2015-01-01 00:00:00

  • Suppression of IL-8 gene transcription by resveratrol in phorbol ester treated human monocytic cells.

    abstract::Resveratrol (3,4',5-trihydroxy-trans-silbene), a natural phytoalexin found in grapes and other food products, has promising anti-inflammatory and anticancer effects. To observe the modulation of interleukin-8 (IL-8) production in human monocytic cells by resveratrol and explore its mechanism at the gene transcription ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000066852

    authors: Shen F,Chen SJ,Dong XJ,Zhong H,Li YT,Cheng GF

    更新日期:2003-06-01 00:00:00

  • Crassicaulisine, a new sulphonoglycolipid from the red alga Chondria crassicaulis Harv.

    abstract::A new sulphonoglycolipid, crassicaulisine, has been isolated from the red alga Chondria crassicaulis Harv.. Four known compounds were also found from the title plant. The structure of the new compound was elucidated on the basis of chemical reactions and spectroscopic analysis. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290024004

    authors: Shao ZY,Cai JN,Ye QZ,Guo YW

    更新日期:2002-09-01 00:00:00

  • A new sesquiterpenoid metabolite from Psilocybe samuiensis.

    abstract::A novel 2,3-secoaromadendrane-type sesquiterpenoid metabolite, psilosamuiensin A (1), was isolated from the broth of Psilocybe samuiensis. The structure of psilosamuiensin A was established by spectroscopic data and its configurations were confirmed by single crystal X-ray crystallographic analysis. This is the first ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802435794

    authors: Pornpakakul S,Suwancharoen S,Petsom A,Roengsumran S,Muangsin N,Chaichit N,Piapukiew J,Sihanonth P,Allen JW

    更新日期:2009-01-01 00:00:00

  • One new dihydrobenzofuran lignan from Vitex trifolia.

    abstract::A new benzofuran-type lignan, vitrifol A (1), was isolated from the fruits of Vitex trifolia, along with three known compounds 2-4. Their structures were elucidated mainly on the basis of 1D, 2D NMR and MS spectral data. Compound 1 was first isolated as a dimer of dihydrobenzofuran-type lignan. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020801967359

    authors: Gu Q,Zhang XM,Zhou J,Qiu SX,Chen JJ

    更新日期:2008-05-01 00:00:00

  • Isolation of two new C-glucofuranosyl isoflavones from Pueraria lobata (Wild.) Ohwi with HPLC-MS guiding analysis.

    abstract::A profiling analysis of the total isoflavone extract of the root of Pueraria lobata (Wild.) Ohwi was performed using HPLC coupled with ESI-ion trap mass spectrometry. A total of seven isoflavones were identified according to their retention times, UV, MS data, and comparing with the literature data. Among them, two pr...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286021003745445

    authors: Zhang HJ,Yang XP,Wang KW

    更新日期:2010-04-01 00:00:00

  • New cytotoxic steroids from the fruits of Syzygium siamense.

    abstract::A new sterol, stigmast-5-ene-3beta,17alpha-diol (1), together with six known compounds, stigmast-5-ene-3beta-yl formate (2), stigmast-5-ene-3beta,7alpha-diol (3), stigmast-5-ene-7alpha-methoxy-3beta-ol (4), stigmast-5-ene-3-one (5), 3beta-sitostanol (6), and 3beta-sitosterol (7), was isolated from the fruits of Syzygi...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286021003762028

    authors: Chumkaew P,Kato S,Chantrapromma K

    更新日期:2010-05-01 00:00:00

  • Two new selaginellin derivatives from Selaginella tamariscina (Beauv.) Spring.

    abstract::Two new selaginellin derivatives, selaginellins K (1) and L (2), were isolated from Selaginella tamariscina (Beauv.) Spring and characterized as 2-formyl-4,4'-dihydroxy-3-[(4-hydroxyphenyl)ethynyl]biphene and 4,4'-dihydroxy-2-methyl-3-[(4-hydroxyphenyl)ethynyl]biphene on the basis of their spectroscopic data including...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.558840

    authors: Xu KP,Zou H,Li FS,Xiang HL,Zou ZX,Long HP,Li J,Luo YJ,Li YJ,Tan GS

    更新日期:2011-04-01 00:00:00

  • Paniculacin, a new coumarin derivative from Murraya paniculata.

    abstract::Paniculacin (1), a new coumarin derivative, has been isolated from the ethyl acetate soluble fraction of the ethanolic extract of Murraya paniculata along with umbelliferone, scopoletin, 4-hydroxybenzoic acid, trans-cinnamic acid, and β-sitosterol. Their structures were elucidated on the basis of spectral data. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.586343

    authors: Saeed S,Shah S,Mehmood R,Malik A

    更新日期:2011-08-01 00:00:00

  • Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer.

    abstract::Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂, and ginsenoside Rh₁₃. Their structures were elucidated as (20S)-3β,6α,12β,20-tetrahydroxydammara-25-ene-2...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.508035

    authors: Liu GY,Li XW,Wang NB,Zhou HY,Wei W,Gui MY,Yang B,Jin YR

    更新日期:2010-10-01 00:00:00

  • New polyoxygenated cyclohexene and polyoxygenated seco-cyclohexene from Uvaria boniana.

    abstract::A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.743529

    authors: Chen Z,Liu YL,Xu QM,Liu JY,Duan HQ,Yang SL

    更新日期:2013-01-01 00:00:00

  • Chemical constituents from the stem barks of Garcinia multiflora.

    abstract::Investigation of the constituents from the stem barks of Garcinia multiflora has yielded two new compounds, multiflorabiphenyl A (1) and 24-p-E-coumaroyl-tetracosanyl (E)-ferulate (2), along with 10 known compounds, friedelin (3), friedelan-3β-ol (4), α,β-amyrin (5), rheediachromenoxanthone (6), 1,7-dihydroxyxanthone ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.819854

    authors: Jing WY,Jiang C,Ji F,Hua HM,Li ZL

    更新日期:2013-11-01 00:00:00

  • Triterpene saponins from the leaves of Ilex kudingcha.

    abstract::Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902937491

    authors: Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

    更新日期:2009-06-01 00:00:00

  • Four new oleanane type saponins from Morina nepalensis var. alba.

    abstract::Four new oleanane type saponins, monepalosides G-J (1-4), were isolated from the water-soluble part of the whole plant of Morina nepalensis var. alba Hand-Mazz. On the basis of chemical and spectroscopic evidence, their structures were determined as 3-O-alpha-L-arabinopyranosyl-(1 --> 3)-alpha-L-arabinopyranosyl olean...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290028965

    authors: Teng RW,Xie HY,Liu XK,Wang DZ,Yang CR

    更新日期:2003-06-01 00:00:00

  • Four new triterpenes from the endemic relict shrub Tetraena mongolica.

    abstract::A chemical investigation of the endemic relict shrub Tetraena mongolica led to the isolation of four new triterpenes: 11α,12α:13β,28-diepoxyoleanane-3β-yl trans-caffeate (1), 3β-hydroxy-11α,12α-epoxyoleanane-28-al (2), olean-11-en-28-al-3β-yl trans-caffeate (3), and 28-acetoxy-olean-12-en-3β-yl trans-caffeate (4). The...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.699525

    authors: Tang SA,Ding LL,Zhai HY,Qin N,Duan HQ

    更新日期:2012-01-01 00:00:00

  • Three new lignan glycosides from the fruits of Forsythia suspense.

    abstract::Two new lignan glycosides forsythiayanoside A (1) and forsythiayanoside B (2), one new stereoisomer of lignan glycoside (+)-8-hydroxyepipinoresinol-4-O-β-D-glucopyranoside (3), together with seven known compounds (4-10), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. Compounds 4 and 10 were isolate...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.917631

    authors: Yan XJ,Peng Y,Liu ZX,Wen J,Liu QB,Li LZ,Song SJ

    更新日期:2014-01-01 00:00:00

  • Constituents from the roots of Heracleum rapula Franch.

    abstract::A new coumarin glucoside, 8-hydroxy-5-O-beta-D-glucosylpsoralen, along with 17 known coumarins and one steroid, was isolated from the roots of Heracleum rapula Franch. Four coumarin glucosides, including the new one, were obtained from the water-soluble fraction. The other coumarins isolated from the ethyl acetate-fra...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290019677

    authors: Niu XM,Li SH,Jiang B,Zhao QS,Sun HD

    更新日期:2002-03-01 00:00:00

  • A novel oxybis cresol verticilatin with highly varying degrees of biological activities from the insect pathogenic fungus Paecilomyces verticillatus.

    abstract::A novel oxybis cresol compound named verticilatin (1), together with two known compounds, 5-methylresorcinol (2) and 2,4-dihydroxy-3,6-dimethylbenzaldehyde (3), was isolated from cultures of the insect pathogenic fungi Paecilomyces verticillatus. The structures of compounds were determined by extensive spectroscopic a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.959438

    authors: Wei PY,Li L,Yang CG,Luo DQ,Zheng ZH,Lu XH,Shi BZ

    更新日期:2014-12-01 00:00:00

  • Coumarins from Daphne feddei and their potential anti-inflammatory activities.

    abstract::Chemical examination of the methanolic extract from the stem bark of Daphne feddei led to the isolation of three new dicoumarin glucosides (1-3), and eight known coumarins, dicoumarins and dicoumarin glucosides. Their structures were elucidated by extensive analysis of spectral data and comparison with the literature ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.621892

    authors: Liang S,Feng Y,Tian JM,Lu M,Xiong Z,Zhang WD

    更新日期:2011-12-01 00:00:00

  • Structural revision of methyl tortuoate D, a bis-cembranoid from Hainan Sarcophyton tortuosum and its absolute stereochemistry.

    abstract::Methyl tortuoate D (1), together with five other known related bis-cembranoids, was isolated from Hainan soft coral Sarcophyton tortuosum. The structure of methyl tortuoate D (1a), firstly isolated and reported by Li et al. from the title organism, was corrected as 1 by an extensive analysis of its one-dimensional and...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.787988

    authors: Li YF,He LL,Liu HL,Liang LF,Zhang HB,Guo YW

    更新日期:2013-01-01 00:00:00

  • A new biologically active flavone glycoside from the seeds of Cassia fistula (Linn.).

    abstract::A new bioactive flavone glycoside 1 [mp 252-254 degrees C, C28H32O16, [M]+ 624 (EIMS)] was isolated from the acetone soluble fraction of the defatted seeds of Cassia fistula (Linn.). It was characterized as a new bioactive flavone glycoside 5,3',4'-tri-hydroxy-6-methoxy-7-O-alpha-L-rhamnopyranosyl-(1 --> 2)-O-beta-D-g...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000080478

    authors: Yadava RN,Verma V

    更新日期:2003-03-01 00:00:00

  • Carbazole alkaloids as new cell cycle inhibitor and apoptosis inducers from Clausena dunniana Levl.

    abstract::Carbazole alkaloids, 3-methylcarbazole (1), murrayafoline A (2), girinimbine (3), mahanimbine (4) and bicyclomahanimbine (5), were isolated for the first time from Clausena dunniana Levl. by bioassay-guided separation procedure and were identified by spectroscopic methods. Compounds 1-5 showed growth inhibitory activi...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602021000049041

    authors: Cui CB,Yan SY,Cai B,Yao XS

    更新日期:2002-12-01 00:00:00

  • Chemical constituents of Nouelia insignis Franch.

    abstract::Two new diterpenes and ent-15alpha-hydroxykaur-16-en-19-oic acid 11,12-acetonide (3), together with 23 known compounds were isolated from the dried aerial parts of Nouelia insignis Franch. The structures of new compounds were determined to be ent-14beta,15alpha-dihydroxykaur-16-en-19-oic acid (1), ent-14beta-hydroxy-1...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020701189500

    authors: Hu XY,Luo YG,Chen XZ,Zhou L,Zhang GL

    更新日期:2008-01-01 00:00:00

  • Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives.

    abstract::A novel series of acylide derivatives have been synthesized which exhibit in vitro potency against key respiratory pathogens. Modification of position 3 was accomplished by replacing different 3-O-substituted acyl groups in the macrolide core via a facile procedure. Compounds 7a-7i were eventually yielded by the conju...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020903176461

    authors: Xu P,Liu L,He W,Li Y,Liu J,Lei PS

    更新日期:2009-10-01 00:00:00

  • The first total synthesis of anemarchalconyn and anemarcoumarin A.

    abstract::Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1275583

    authors: Zhang JX,Li ZY,Wang YC,Ma WB,Hou M,Cao SH,Tang KH,Dong HB

    更新日期:2017-09-01 00:00:00

  • Cytotoxic activity of a synthetic deoxypodophyllotoxin derivative with an opened D-ring.

    abstract::Podophyllotoxin and its synthetic derivatives are valuable medicinal agents that have antitumor, insecticidal, and antifungal properties. We previously synthesized a deoxypodophyllotoxin derivative with an opened D-ring (DPD) exhibiting potent insecticidal activity. This article was firstly performed to identify the c...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1131679

    authors: Chen C,Wang CC,Wang Z,Geng WY,Xu H,Song XM,Luo DQ

    更新日期:2016-05-01 00:00:00

  • Two new C-glucosyl flavonoids from Ziziphus jujube and their anti-inflammatory activity.

    abstract::Two new C-glucosyl flavonoids 6''-O-feruloylspinosin and 6''-O-feruloyl-6'''-p-hydroxybenzoylspinosin, together with five known compounds, were isolated from the seeds of Ziziphus jujube (Rhamnaceae family). Their structures were elucidated on the basis of chemical and spectroscopic evidences. Compounds 1-7 showed mod...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1234458

    authors: Fu Q,Ma Y,Chen J,Yuan HM,Zheng YZ

    更新日期:2017-05-01 00:00:00