Two new p-coumaroylated sesquiterpenoids from Pilea cavaleriei.

Abstract:

:A new p-coumaroylated santalane-type sesquiterpenoid, 8-p-coumaroyl-α-santalene (1), a new p-coumaroylated oplopanane-type sesquiterpenoid, 8-β-p-coumaroyl-oplopanone (2), and three known p-coumaroylated humulene-type sesquiterpenoids (3-5) were isolated from the ethanol extract of the whole herbs of Pilea cavaleriei. Their structures were elucidated based on the combination of 1D and 2D NMR and HRMS methods. Compound 2 was found to show anti-tuberculosis activity with MIC of 16 μg/ml.

journal_name

J Asian Nat Prod Res

authors

Ren HC,Zhang J,Liang H

doi

10.1080/10286020.2017.1320990

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

109-116

issue

2

eissn

1028-6020

issn

1477-2213

journal_volume

20

pub_type

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