Abstract:
:Chemical examination of the methanolic extract from the stem bark of Daphne feddei led to the isolation of three new dicoumarin glucosides (1-3), and eight known coumarins, dicoumarins and dicoumarin glucosides. Their structures were elucidated by extensive analysis of spectral data and comparison with the literature values. All compounds were tested for inhibitory activity against lipopolysaccharide-induced NO production in RAW 264.7 macrophages, and compounds 4 and 5 showed potent inhibitory activity with IC₅₀ values of 0.161 and 0.127 μM, respectively.
journal_name
J Asian Nat Prod Resjournal_title
Journal of Asian natural products researchauthors
Liang S,Feng Y,Tian JM,Lu M,Xiong Z,Zhang WDdoi
10.1080/10286020.2011.621892subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1074-80issue
12eissn
1028-6020issn
1477-2213journal_volume
13pub_type
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