Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives.

abstract：:Two new C21 steroidal glycosides were isolated from Cynanchum wallichii Wight. Their structures were elucidated as caudatin-3-O-β-d-glucopyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-digitoxopyranoside (1) and caudatin-3-O-β-d-glucopyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-ole...

journal_title：Journal of Asian natural products research

authors： Wang D,Pan WH,Bao YR,Yang XX,Meng XS

更新日期：2014-01-01 00:00:00

abstract：:A new ester, 2-(4'-hydroxyphenyl)ethyl dotriacontanoate (1), and a new inseparable mixture of octacosan-1,28-dioldiferulate and triacontan-1,30-dioldiferulate (2) were isolated from the stem barks of Stereospermum acuminatissimum, along with 24 known compounds including 4 triterpenoids, 11 anthraquinones, 2 lignans, 3...

journal_title：Journal of Asian natural products research

authors： Sob SV,Wabo HK,Tang CP,Tane P,Ngadjui BT,Ye Y

更新日期：2011-12-01 00:00:00

abstract：:Andrographolide, a major bioactive compound isolated from Andrographis paniculata (Burm. F.) Nees, was evaluated for its effects on the hOAT1 membrane transporter. Substrate determination and inhibition of hOAT1-mediated uptake transport assay was carried out using recombinant CHO-hOAT1 cells. The results showed that ...

journal_title：Journal of Asian natural products research

authors： Chong YM,Kaur G,Tan ML

更新日期：2019-08-01 00:00:00

abstract：:Eutypellol A (1), the first norsesquiterpenoid of sequicarene family, as well as eutypellol B (2), a rare 7-methyl oxidized 2-carene derivative, and one new natural product 2-(2-hydroxy-4-methylcyclohex-3-enyl)propanoic acid (3), along with eight known terpenoids, were isolated from the marine sediment-derived fungus ...

journal_title：Journal of Asian natural products research

authors： Liu HX,Zhang L,Chen YC,Sun ZH,Pan QL,Li HH,Zhang WM

更新日期：2017-02-01 00:00:00

abstract：:(+)-Lariciresinol 3a-acetate [(+)-(3S)-acetyloxymethyl-(2S)-(4-hydroxy-3-methoxyphenyl)-(4R)-[(4-hydroxy-3-methoxyphenyl)methyl]tetrahydrofuran] (1), a metabolite of A. elaeagnoidea was synthesized starting from (-)-lariciresinol (2) in three steps with an overall yield of 66%. ...

journal_title：Journal of Asian natural products research

authors： Rajasekhar D,Subbaraju GV

更新日期：2000-01-01 00:00:00

abstract：:Epoxyeicosatrienoic acids (EETs) and their regulating enzyme soluble epoxide hydrolase (sEH) have been associated with ischemic stroke. Salvianolic acid A (SAA) is proved to display potent cerebroprotection. However, little information is available about the link between them. This study aimed to investigate whether S...

journal_title：Journal of Asian natural products research

authors： Wang SB,Pang XB,Zhao Y,Wang YH,Zhang L,Yang XY,Fang LH,Du GH

更新日期：2012-01-01 00:00:00

abstract：:A new phenyldihydronaphthalene-type lignan, vitexdoin F (1), along with 22 known lignan derivatives (2-23) was isolated from the seeds of Vitex negundo var. cannabifolia. Their structures were established by comprehensive 1D and 2D NMR spectroscopic analyses. The antioxidant activities of these lignans were evaluated ...

journal_title：Journal of Asian natural products research

authors： Lou ZH,Li HM,Gao LH,Li RT

更新日期：2014-01-01 00:00:00

abstract：:One new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide C (5), viridicatin (6), 3-O-methylviridicatin (7), verrucosidin (8), ergoster...

journal_title：Journal of Asian natural products research

authors： Li J,Wang J,Jiang CS,Li G,Guo YW

更新日期：2014-01-01 00:00:00

abstract：:Two new flavonoid alkaloids, 8-(2''-pyrrolidinone-5''-yl)-quercetin (1) and 8-(2''-pyrrolidinone-5''-yl)-isorhamnetin (2), were isolated from the herb of Senecio argunensis. Their structures were elucidated by spectral analysis. ...

journal_title：Journal of Asian natural products research

authors： Li N,Shao L,Zhang CF,Zhang M

更新日期：2008-11-01 00:00:00

abstract：:Two new C19-diterpenoid alkaloids, straconitines A (1) and B (2), were isolated from the roots of Aconitum straminiflorum. Their structures were elucidated as 14-benzoylducloudine D (1) and 6-hydroxy-14-benzoylducloudine D (2) based on spectroscopic analysis, including IR, ESI-MS, HR-ESI-MS, 1D, and 2D NMR. ...

journal_title：Journal of Asian natural products research

authors： Qi Y,Zhao DK,Zi SH,Zhang LM,Guo CX,Li GQ,Xun JJ,Shen Y

更新日期：2016-01-01 00:00:00

abstract：:Four new oleanane type saponins, monepalosides G-J (1-4), were isolated from the water-soluble part of the whole plant of Morina nepalensis var. alba Hand-Mazz. On the basis of chemical and spectroscopic evidence, their structures were determined as 3-O-alpha-L-arabinopyranosyl-(1 --> 3)-alpha-L-arabinopyranosyl olean...

journal_title：Journal of Asian natural products research

authors： Teng RW,Xie HY,Liu XK,Wang DZ,Yang CR

更新日期：2003-06-01 00:00:00

abstract：:Bioassay-guided fractionation of the ethanolic extract of Senecio scandens led to the isolation of four new compounds 4, 5, 7, and 8, along with four known jacaranone analogs (1, 2, 3, 6). Their structures were elucidated on the basis of spectral and chemical evidence. Compound 7 was obtained as a tautomeric mixture o...

journal_title：Journal of Asian natural products research

authors： Tian XY,Wang YH,Yang QY,Yu SS,Fang WS

更新日期：2009-01-01 00:00:00

abstract：:Two new phthalates bis(2-ethylundecyl)phthalate and bis(2-ethyltridecyl)phthalate have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei along with one known compound β-amyrin. The structures of the two new compounds and β-amyrin were assigned on the basis of their ¹H and ¹³C NMR s...

journal_title：Journal of Asian natural products research

authors： Hussain J,Rehman NU,Hussain H,Ali L,Al-Harrasi A

更新日期：2012-01-01 00:00:00

abstract：:Two new anthraquinones, methyl 8-hydroxy-3-methoxy-6,7-methylenedioxy-1-methylanthraquinone-2-carboxylate (gandavensin A, 1) and methyl 8-hydroxy-3,6,7-trimethoxy-1-methylanthraquinone-2-carboxylate (gandavensin B, 2), have been isolated from the light petroleum extract of the subterranean corm of Gladiolus gandavensi...

journal_title：Journal of Asian natural products research

authors： Wang DY,Ye Q,Zhang GL,Li BG

更新日期：2003-12-01 00:00:00

abstract：:Four nitrogen-containing derivatives of ginkgolide B were synthesized to improve the physical-chemical properties and bioavailability of ginkgolide B. The reaction was accomplished with the nitrogen atom as neighboring group participating in the replacement reaction. All of the four compounds were proved to have excel...

journal_title：Journal of Asian natural products research

authors： Guo CJ,Ren Y,Qin YL,Zhang Q

更新日期：2008-09-01 00:00:00

abstract：:Barlericin, the new neolignan diglycoside, has been isolated from the n-butanol soluble sub-fraction of Barleria acanthoides along with dehydrodiconiferyl alcohol 12-O-beta-D-glucopyranoside (2), reported for the first time from the genus Barleria. Their structures have been assigned on the basis of spectral studies. ...

journal_title：Journal of Asian natural products research

authors： Karim A,Noor AT,Malik A

更新日期：2010-08-01 00:00:00

abstract：:Six thiophenes were isolated and purified from ethanol extract of the roots of Echinops latifolius Tausch. Their structures were identified on the basis of spectral data. Among them, 5-(3-hydroxmethyl-3-isovaleroyloxyprop-1-ynyl)-2,2'-bithiophene (6) is a new compound, and 5-(3-hydroxy-4-isovaleroyloxybut-1-ynyl)-2,2'...

journal_title：Journal of Asian natural products research

authors： Wang Y,Li X,Meng DL,Li ZL,Zhang P,Xu J

更新日期：2006-10-01 00:00:00

abstract：:Two new acetylated flavan glycosides (2S,4R)-4,5,7-trihydroxy-4'-methoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (1) and (2S,4R)-5,7-dihydroxy-4,4'-dimethoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (2) were isolated from the rhizomes of Abacopteris ...

journal_title：Journal of Asian natural products research

authors： Zhao ZX,Ruan JL,Jin J,Zhu CC,Lin CZ

更新日期：2010-12-01 00:00:00

abstract：:A new sulphonoglycolipid, crassicaulisine, has been isolated from the red alga Chondria crassicaulis Harv.. Four known compounds were also found from the title plant. The structure of the new compound was elucidated on the basis of chemical reactions and spectroscopic analysis. ...

journal_title：Journal of Asian natural products research

authors： Shao ZY,Cai JN,Ye QZ,Guo YW

更新日期：2002-09-01 00:00:00

abstract：:A series of novel tetrandrine (Tet) derivatives were synthesized through Suzuki -Miyaura reaction and evaluated for their cytotoxicity against human non-small cell lung carcinoma (NSCLC) A549 cells. Interestingly, most of derivatives showed similar cytotoxicity to Tet against NSCLC A549 cells, and particularly, compou...

journal_title：Journal of Asian natural products research

authors： Yang QH,Jiang CS,Jin T,Xu JF,Qu TL,Guo YW,Zhao ZB

更新日期：2018-11-01 00:00:00

abstract：:Mucor spinosus has been employed for the biotransformation of cinobufagin (1) to afford three metabolites. On the basis of their physico-chemical data, the structures of the transformation products have been characterized as 1beta-hydroxy-cinobufagin (2), 12beta-hydroxy-cinobufagin (3) and 1beta,12beta-dihydroxy-cinob...

journal_title：Journal of Asian natural products research

authors： Zhang W,Ye M,Qu GQ,Wu WY,Chen YJ,Guo DA

更新日期：2005-06-01 00:00:00

abstract：:Three new alkylated benzoquinones, 2-hydroxy-5-ethoxy-3-nonyl-1,4-benzoquinone (1), 5-O-butyl-embelin (2), and 2,5-dihydroxy-6-methyl-3-pentadecyl-1,4-benzoquinone (3), together with seven known analogues (4-10), were isolated from the stems and twigs of mangrove plant, Aegiceras corniculatum. Their structural elucida...

journal_title：Journal of Asian natural products research

authors： Li Y,Dong C,Xu MJ,Lin WH

更新日期：2020-02-01 00:00:00

abstract：:An investigation of CH(2)Cl(2) and EtOH extracts of Trifolium resupinatum L. var. microcephalum Zoh. has led to the isolation of two new compounds characterized as 4,15-dimethyl-2-(1,2-dihydroxyethyl)-hexadecene (1) and 1-undecene-1-O-beta-2',3',4',6'-tetraacetyl glucopyranoside (2a). Their structures were established...

journal_title：Journal of Asian natural products research

authors： Sabudak T,Isik E,Oksuz S

更新日期：2008-11-01 00:00:00

abstract：:Two new guaianolides artemanomalides A and B were isolated from the aerial parts of Artemisia anomala S. Moore. Their structures were characterized as 2-oxo-5α, 10α-dihydroxy-guaia-3-en-1α, 6β, 7α, 11β H-12, 6-olide (1) and 8α-acetoxy-2-oxo-5α, 10α-dihydroxy-guaia-3, 11(13)-dien-1α, 6β, 7αH-12, 6-olide (2) on the basi...

journal_title：Journal of Asian natural products research

authors： Hu ZH,Zhang P,Huang DB,Wu JZ

更新日期：2012-01-01 00:00:00

abstract：:Three new flavonol glycosides, kaempferol-3-O-(6-trans-caffeoyl)-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside (1), kaempferol-3-O-(6-trans-caffeoyl)-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside-7-O-beta-D-glucopyranoside (2), and kaempferol-3-O-(6-trans-p-coumaroyl)-beta-D-glucopyranosyl-(1 --> 2)-...

journal_title：Journal of Asian natural products research

authors： Li N,Li X,Meng DL,Guo YQ,Wang JH

更新日期：2006-01-01 00:00:00

abstract：:One new flavone, 5,7-dihydroxy-8,2',3',6'-tetramethoxyflavone (1), and one new flavonol, 5,7,6'-trihydroxy-2'-methoxyflavonol (2), were isolated from the roots of Scutellaria baicalensis, and their structures were elucidated on the basis of extensive spectroscopic evidences, especially 1D and 2D NMR and HR-ESI-MS expe...

journal_title：Journal of Asian natural products research

authors： Long HL,Xu GY,Deng AJ,Li ZH,Ma L,Lu Y,Zhang ZH,Wu F,Qin HL

更新日期：2015-01-01 00:00:00

abstract：:The Amaranthaceae plant, Pfaffia glomerata, which is so-called as Brazil ginseng, is widely distributed in South American countries. Three new noroleanane-type triterpenes and four known oleanane-type triterpenes were isolated from the roots of P. glomerata. Their structures were determined by spectroscopic methods in...

journal_title：Journal of Asian natural products research

authors： Han YZ,Zhou Y,Zhang ZT,Niu SY,Liu XH,Jia XY

更新日期：2018-05-01 00:00:00

abstract：:Two new resin glycosides, batataosides I (1) and II (2), and five known compounds, friedelin (3), scopoletin (4), octadecyl caffeate (5), beta-sistosterol (6) and daucosterol (7), were isolated from the roots of Ipomoea batatas. Their structures have been determined based on the chemical and spectral data. Batataoside...

journal_title：Journal of Asian natural products research

authors： Yin YQ,Kong LY

更新日期：2008-03-01 00:00:00

abstract：:Six new sesquiterpenes, 10-hydroxy-epiaplysin (1), 10-hydroxy-aplysin (2), 10-hydroxy-debromoepiaplysin (3), aplysin-9-ene (4), epiaplysinol (5) and debromoepiaplysinol (6), together with 13 known compounds (7-19), have been isolated from the red alga Laurencia tristicha. The structures of 1-6 were determined by spect...

journal_title：Journal of Asian natural products research

authors： Sun J,Shi DY,Li S,Wang SJ,Han LJ,Fan X,Yang YC,Shi JG

更新日期：2007-09-01 00:00:00

abstract：:Fasciospyrinadine (1), a novel sesquiterpene pyridine alkaloid with a previously unreported skeleton featuring a monocyclicfarnesane moiety attached to a 3-methylenepyridine residue, was isolated from the sponge Fasciospongia sp. from Weizhou Island, Guangxi Autonomous Region. The structure and the relative stereochem...

journal_title：Journal of Asian natural products research

authors： Zhao ZB,Sun JZ,Mao SC,Guo YW

更新日期：2013-01-01 00:00:00