Monoterpenes and sesquiterpenes from the marine sediment-derived fungus Eutypella scoparia FS46.

Abstract:

:Eutypellol A (1), the first norsesquiterpenoid of sequicarene family, as well as eutypellol B (2), a rare 7-methyl oxidized 2-carene derivative, and one new natural product 2-(2-hydroxy-4-methylcyclohex-3-enyl)propanoic acid (3), along with eight known terpenoids, were isolated from the marine sediment-derived fungus Eutypella scoparia FS46 collected from the South China Sea. Their structures were established on the basis of extensive spectroscopic analysis. Compounds 1-3 were evaluated for their antibacterial activities against Staphylococcus aureus and cytotoxic activities against MCF-7, NCI-H460, and SF-268 tumor cell lines.

journal_name

J Asian Nat Prod Res

authors

Liu HX,Zhang L,Chen YC,Sun ZH,Pan QL,Li HH,Zhang WM

doi

10.1080/10286020.2016.1189906

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

145-151

issue

2

eissn

1028-6020

issn

1477-2213

journal_volume

19

pub_type

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