Monoterpenes and sesquiterpenes from the marine sediment-derived fungus Eutypella scoparia FS46.

Abstract:

:Eutypellol A (1), the first norsesquiterpenoid of sequicarene family, as well as eutypellol B (2), a rare 7-methyl oxidized 2-carene derivative, and one new natural product 2-(2-hydroxy-4-methylcyclohex-3-enyl)propanoic acid (3), along with eight known terpenoids, were isolated from the marine sediment-derived fungus Eutypella scoparia FS46 collected from the South China Sea. Their structures were established on the basis of extensive spectroscopic analysis. Compounds 1-3 were evaluated for their antibacterial activities against Staphylococcus aureus and cytotoxic activities against MCF-7, NCI-H460, and SF-268 tumor cell lines.

journal_name

J Asian Nat Prod Res

authors

Liu HX,Zhang L,Chen YC,Sun ZH,Pan QL,Li HH,Zhang WM

doi

10.1080/10286020.2016.1189906

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

145-151

issue

2

eissn

1028-6020

issn

1477-2213

journal_volume

19

pub_type

杂志文章
  • C₁₄-polyacetylene glucosides from Codonopsis pilosula.

    abstract::Seven new C14-polyacetylene glucosides codonopilodiynosides A-G (1-7) were isolated from an aqueous extract of the Codonopsis pilosula roots. Their structures were determined by spectroscopic and chemical methods as (-)-(5S,6E,12E)-tetradeca-6,12-dien-8,10-diyn-1,5,14-triol 5-O-β-D-glucopyranoside (1), (-)-(5S,6E,12E)...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1041932

    authors: Jiang YP,Liu YF,Guo QL,Jiang ZB,Xu CB,Zhu CG,Yang YC,Lin S,Shi JG

    更新日期:2015-01-01 00:00:00

  • New lignans from Urticae Fissae Herba.

    abstract::Two new lignans named neourticol A (1) and neourticol B (2), together with seven known compounds (3-9), were isolated from Urticae Fissae Herba, a folk medicine for rheumatism arthritis in China. The active evaluation results showed that 1 and 2 possessed the potent anti-complement and anti-inflammatory activities. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1457652

    authors: Wang MY,Zhang Y,Zhang H,Feng XR,Li XB

    更新日期:2019-06-01 00:00:00

  • New alkylated benzoquinones from mangrove plant Aegiceras corniculatum with anticancer activity.

    abstract::Three new alkylated benzoquinones, 2-hydroxy-5-ethoxy-3-nonyl-1,4-benzoquinone (1), 5-O-butyl-embelin (2), and 2,5-dihydroxy-6-methyl-3-pentadecyl-1,4-benzoquinone (3), together with seven known analogues (4-10), were isolated from the stems and twigs of mangrove plant, Aegiceras corniculatum. Their structural elucida...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1540604

    authors: Li Y,Dong C,Xu MJ,Lin WH

    更新日期:2020-02-01 00:00:00

  • Cytotoxic lanostanoid triterpenes from Ganoderma lucidum.

    abstract::Two new lanostanoid triterpenes, 23S-hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic acid (1), and 12beta-acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20E-diene-26-oic acid (16), together with 17 known compounds, were isolated from the fruit bodies of Ganoderma lucidum. Their structures were established by ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802016297

    authors: Guan SH,Xia JM,Yang M,Wang XM,Liu X,Guo DA

    更新日期:2008-07-01 00:00:00

  • Two new 2-phenylethylchromones from artificial agarwood by holing method.

    abstract::Two new 2-(2-phenylethyl)chromone derivatives (1-2) were isolated from the ethyl acetate extract of artificial agarwood induced by holing method originating from Aquilaria sinensis (Lour.) Gilg, and they were isolated from this genus for the first time. The structures of these two new compounds were elucidated by exte...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1860029

    authors: Xiang P,Zeng YB,Wang H,Kong FD,Chen HQ,Mei WL,Dai HF

    更新日期:2020-12-18 00:00:00

  • Hepatic metabolism: a key component of herbal drugs research.

    abstract::Liver is the largest metabolic organ for a wide range of endogenous and exogenous compounds and plays a crucial part in the pharmacokinetics and pharmacodynamics through various metabolic reactions. This review provides a progressive description of hepatic metabolism of herbal drugs with respect to metabolic types and...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章,评审

    doi:10.1080/10286020.2014.960856

    authors: Peng YS,Liu B,Wang RF,Zhao QT,Xu W,Yang XW

    更新日期:2015-01-01 00:00:00

  • Structure of barlericin, the neolignan diglycoside from Barleria acanthoides.

    abstract::Barlericin, the new neolignan diglycoside, has been isolated from the n-butanol soluble sub-fraction of Barleria acanthoides along with dehydrodiconiferyl alcohol 12-O-beta-D-glucopyranoside (2), reported for the first time from the genus Barleria. Their structures have been assigned on the basis of spectral studies. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.489895

    authors: Karim A,Noor AT,Malik A

    更新日期:2010-08-01 00:00:00

  • Further studies on CAB approach toward chemical conversion of C19-diterpenoid alkaloids to taxoids: synthesis of the vital intermediate C-nor-aconanone.

    abstract::In the title study, the synthesis of the vital intermediate C-nor-aconanone (3) from 4 was completed through 11 steps, mainly including semipinacol rearrangement, formation of the imines by the treatment of 10 or 20 with NBS, the cleavage of N-C19 bonds in 11 or 21 by treatment with m-CPBA and subsequently with LTA, a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020801967128

    authors: Shen XL,Chen QH,Wang FP

    更新日期:2009-01-01 00:00:00

  • New polyoxygenated cyclohexene and polyoxygenated seco-cyclohexene from Uvaria boniana.

    abstract::A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.743529

    authors: Chen Z,Liu YL,Xu QM,Liu JY,Duan HQ,Yang SL

    更新日期:2013-01-01 00:00:00

  • Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L.

    abstract::Five labdane-type diterpenes, vitexilactone (1), (rel 5S,6R,8R,9R,10S)-6-acetoxy-9-hydroxy-13(14)-labden-16,15-olide (2), rotundifuran (3), vitetrifolin D (4), and vitetrifolin E (5), have been isolated from Vitex trifolia L., a Chinese folk medicine used to treat cancers, as new cell cycle inhibitors and apoptosis in...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020310001617165

    authors: Li WX,Cui CB,Cai B,Yao XS

    更新日期:2005-04-01 00:00:00

  • Methoxylated fatty acids from the bark of Fraxinus sieboldiana.

    abstract::Nine new fatty acid derivatives, including seven methoxylated (1, 2, and 4-8) and two hydroxylated (3 and 9) fatty acids, have been isolated from the ethanol extract of the stem bark of Fraxinus sieboldiana. Their structures were determined by spectroscopic methods including IR, MS, 1D, and 2D NMR experiments. The 3- ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.648622

    authors: Lin S,Zhang YL,Liu MT,Zi JC,Gan ML,Song WX,Fan XN,Wang SJ,Yang YC,Shi JG

    更新日期:2012-01-01 00:00:00

  • A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera.

    abstract::A new denitroaristolochic acid, demethylaristofolin C (1), together with six known alkaloids, crebanine N-oxide (2), (-)-sukhodianine-β-N-oxide (3), palmatine (4), corydalmine (5), dehydrocorydalmine (6), and corynoxidine (7), was isolated from the tubers of Stephania succifera. The structure of demethylaristofolin C ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.762641

    authors: Yang DL,Mei WL,Zeng YB,Guo ZK,Wei DJ,Liu SB,Wang QH,Dai HF

    更新日期:2013-01-01 00:00:00

  • Triterpene saponins from the leaves of Ilex kudingcha.

    abstract::Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902937491

    authors: Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

    更新日期:2009-06-01 00:00:00

  • Two new dammarane-type triterpene saponins from red American ginseng.

    abstract::Two new dammarane-type triterpene saponins were isolated from the red American ginseng. The new saponins were named as pseudoginsenoside G(1) and pseudoginsenoside G(2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 3-O-[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl]-dammar-...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.550575

    authors: Liu JP,Lu D,Li PY

    更新日期:2011-03-01 00:00:00

  • Jacaranone analogs from Senecio scandens.

    abstract::Bioassay-guided fractionation of the ethanolic extract of Senecio scandens led to the isolation of four new compounds 4, 5, 7, and 8, along with four known jacaranone analogs (1, 2, 3, 6). Their structures were elucidated on the basis of spectral and chemical evidence. Compound 7 was obtained as a tautomeric mixture o...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802413239

    authors: Tian XY,Wang YH,Yang QY,Yu SS,Fang WS

    更新日期:2009-01-01 00:00:00

  • Two new selaginellin derivatives from Selaginella tamariscina (Beauv.) Spring.

    abstract::Two new selaginellin derivatives, selaginellins K (1) and L (2), were isolated from Selaginella tamariscina (Beauv.) Spring and characterized as 2-formyl-4,4'-dihydroxy-3-[(4-hydroxyphenyl)ethynyl]biphene and 4,4'-dihydroxy-2-methyl-3-[(4-hydroxyphenyl)ethynyl]biphene on the basis of their spectroscopic data including...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.558840

    authors: Xu KP,Zou H,Li FS,Xiang HL,Zou ZX,Long HP,Li J,Luo YJ,Li YJ,Tan GS

    更新日期:2011-04-01 00:00:00

  • New alkaloids from a marine-derived fungus Neosartorya sp.HN-M-3.

    abstract::Two new indole alkaloids, tryptoquivalines R and S, have been isolated from a marine-derived fungus Neosartorya sp.HN-M-3. Their structures were determined on the basis of spectroscopic methods including 1D and 2D NMR experiments. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.797895

    authors: Xu N,Cao Y,Wang L,Chen G,Pei YH

    更新日期:2013-07-01 00:00:00

  • Two new sesquiterpene pyridine alkaloids from root barks of Celastrus angulatus.

    abstract::Two new sesquiterpene pyridine alkaloids, Chinese bittersweet alkaloid A (1) and Chinese bittersweet alkaloid B (2), together with five known compounds 3β- hydroxyolean-9(11),12-diene, β-sitosterol, 1β,2β,6α,15β-tetraacetoxy-8β,9α- dibenzoyloxy-β-dihydroagarofuran, angulatin A and angulatin J, were isolated from the r...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1492563

    authors: Chang X,Wang ZY,Chen X,Ma YN,Zhang HY,Zhao TZ

    更新日期:2019-11-01 00:00:00

  • Two new acetylated flavan glycosides from rhizomes of the fern Abacopteris penangiana.

    abstract::Two new acetylated flavan glycosides (2S,4R)-4,5,7-trihydroxy-4'-methoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (1) and (2S,4R)-5,7-dihydroxy-4,4'-dimethoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (2) were isolated from the rhizomes of Abacopteris ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.525744

    authors: Zhao ZX,Ruan JL,Jin J,Zhu CC,Lin CZ

    更新日期:2010-12-01 00:00:00

  • New abietane diterpenoid glucosides from underground parts of Isodon taliensis.

    abstract::Two new abietane diterpenoid glucosides, talienosides A and B (1 and 2), along with four known compounds (3 - 6), were isolated from the ethyl acetate soluble portion of 70% acetone extract of the underground parts of Isodon taliensis. Their structures were elucidated based on the analyses of extensive spectroscopic d...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1518321

    authors: Xiang P,Xiao CJ,Xu W,Shan H,Qiu L,Li Y,Dong X,Jiang B

    更新日期:2019-12-01 00:00:00

  • Constituents from the roots of Heracleum rapula Franch.

    abstract::A new coumarin glucoside, 8-hydroxy-5-O-beta-D-glucosylpsoralen, along with 17 known coumarins and one steroid, was isolated from the roots of Heracleum rapula Franch. Four coumarin glucosides, including the new one, were obtained from the water-soluble fraction. The other coumarins isolated from the ethyl acetate-fra...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290019677

    authors: Niu XM,Li SH,Jiang B,Zhao QS,Sun HD

    更新日期:2002-03-01 00:00:00

  • A new acylated flavonoid glycoside from the flowers of Camellia nitidissima and its effect on the induction of apoptosis in human lymphoma U937 cells.

    abstract::From the EtOH extract of the flowers of Camellia nitidissima Chi, a new acylated flavonoid glycoside, quercetin 7-O-(6"-O-E-caffeoyl)-β-D-glucopyranoside (1), has been isolated, together with three known flavonoids: quercetin (2), quercetin 3-O-β-D-glucopyranoside (3), and quercetin 7-O-β-D-glucopyranoside (4). Their ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.691475

    authors: Peng X,Yu DY,Feng BM,Wang YQ,Shi LY

    更新日期:2012-01-01 00:00:00

  • A new sterol glycoside from Securidaca inappendiculata.

    abstract::From the roots of Securidaca inappendiculata, one new sterol glycoside securisteroside (1) has been isolated, along with two known sterols, spinasterol (2) and 3-O-beta-D-glucopyranosyl-spinasterol (3). The new sterol was characterized by chemical and spectrometric methods, including EIMS, FABMS and one- and two-dimen...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602032000169569

    authors: Zhang LJ,Yang XD,Xu LZ,Zou ZM,Yang SL

    更新日期:2005-08-01 00:00:00

  • Four new triterpenes from the endemic relict shrub Tetraena mongolica.

    abstract::A chemical investigation of the endemic relict shrub Tetraena mongolica led to the isolation of four new triterpenes: 11α,12α:13β,28-diepoxyoleanane-3β-yl trans-caffeate (1), 3β-hydroxy-11α,12α-epoxyoleanane-28-al (2), olean-11-en-28-al-3β-yl trans-caffeate (3), and 28-acetoxy-olean-12-en-3β-yl trans-caffeate (4). The...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.699525

    authors: Tang SA,Ding LL,Zhai HY,Qin N,Duan HQ

    更新日期:2012-01-01 00:00:00

  • A new sesquiterpenoid metabolite from Psilocybe samuiensis.

    abstract::A novel 2,3-secoaromadendrane-type sesquiterpenoid metabolite, psilosamuiensin A (1), was isolated from the broth of Psilocybe samuiensis. The structure of psilosamuiensin A was established by spectroscopic data and its configurations were confirmed by single crystal X-ray crystallographic analysis. This is the first ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802435794

    authors: Pornpakakul S,Suwancharoen S,Petsom A,Roengsumran S,Muangsin N,Chaichit N,Piapukiew J,Sihanonth P,Allen JW

    更新日期:2009-01-01 00:00:00

  • New xanthone glycosides from Securidaca inappendiculata.

    abstract::Three new xanthone glycosides, securixanside A (1), securixanside B (2), and securixanside C (3) were isolated from the stems of Securidaca inappendiculata. These compounds were characterized by spectrometric and chemical methods, including FABMS and one- and two-dimensional NMR experiments. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290027434

    authors: Yang XD,An N,Xu LZ,Yang SL

    更新日期:2002-06-01 00:00:00

  • New guaianolides from Artemisia anomala.

    abstract::Two new guaianolides artemanomalides A and B were isolated from the aerial parts of Artemisia anomala S. Moore. Their structures were characterized as 2-oxo-5α, 10α-dihydroxy-guaia-3-en-1α, 6β, 7α, 11β H-12, 6-olide (1) and 8α-acetoxy-2-oxo-5α, 10α-dihydroxy-guaia-3, 11(13)-dien-1α, 6β, 7αH-12, 6-olide (2) on the basi...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.634802

    authors: Hu ZH,Zhang P,Huang DB,Wu JZ

    更新日期:2012-01-01 00:00:00

  • Flavone c-glycosides from Trollius ledebouri reichb.

    abstract::A new acylated C-glycosylflavone (1) was isolated from Trollius ledebouri Reichb together with two known C-glycosyflavones (2, 3). The structures were elucidated by spectroscopic methods, including HRMS, IR, 1H and 13C NMR and 2D experiments (COSY, HMQC and HMBC). The anti-inflammatory activities of 1-3 were tested on...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500176922

    authors: Wu XA,Zhao YM,Yu NJ

    更新日期:2006-09-01 00:00:00

  • Two new caffeoyl conjugation from Erigeron breviscapus.

    abstract::Two new constituents with a novel basic skeleton were isolated from Erigeron breviscapus. On the basis of chemical and spectroscopic evidences, the structures of the new compounds were elucidated as 1R,3R-dihydroxy-4S,5R-dicaffeoyloxy cyclohexane carboxylic acid methyl ester (V), 1,4-dihydroxy-3R,5R-dicaffeoyloxy cycl...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020008041367

    authors: Zhang WD,Tam HT,Chen WS,Kong DY,Li HT,Wang YH,Fouraste I

    更新日期:2000-01-01 00:00:00

  • Two new dammarane-type triterpenoid saponins from notoginseng medicinal fungal substance.

    abstract::Two new dammarane-type triterpenoid saponins, namely ginsenoside Rk6 (1) and ginsenoside-Rh22 (2), were isolated from notoginseng medicinal fungal substance. The structures of 1 and 2 were established as 3β,6α,12β,26-tetrahydroxydammar-20(21),24(25)(E)-diene-6-O-β-D-glucopyranoside and 3β,6α, 20(S)-trihydroxy-12(R),23...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1189907

    authors: Xu W,Liu X,Liu XL,Jia AL,Wang XW,Qiu ZD

    更新日期:2016-12-01 00:00:00