Two new naphthalene glycosides from the seeds of Cassia obtusifolia.

Abstract:

:A phytochemical study on the seeds of Cassia obtusifolia was carried out, which finally led to obtain two naphthalenes (1 and 2), two naphthopyrans (3 and 4) and twelve anthraquinones (5-16). The structures of all compounds were established mainly by NMR and MS experiments as well as the necessary chemical evidence. Among them, 1 and 2 (obtusinaphthalensides A and B) were identified to be new naphthalene glycosides.

journal_name

J Asian Nat Prod Res

authors

Pang X,Li NN,Yu HS,Kang LP,Yu HY,Song XB,Fan GW,Han LF

doi

10.1080/10286020.2018.1478816

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

970-976

issue

10

eissn

1028-6020

issn

1477-2213

journal_volume

21

pub_type

杂志文章
  • Two new compounds from rhizomes of Musa basjoo.

    abstract::Two new benzo[de]isoquinoline derivatives, 4-phenyl-benzo[de]isoquinoline-1,3-dione (1) and 4-(4-hydroxyphenyl)-benzo[de]isoquinoline-1,3-dione (2), were isolated from 70% ethanol extract of the rhizomes of Musa basjoo. Their chemical structures were elucidated by HRESIMS, 1 D and 2 D spectra. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2021.1871604

    authors: Ma X,Jiang L,Zhu MH,Liu CH,Wang GC,Li YT,Liu T,Li YJ

    更新日期:2021-01-19 00:00:00

  • Carbazole alkaloids as new cell cycle inhibitor and apoptosis inducers from Clausena dunniana Levl.

    abstract::Carbazole alkaloids, 3-methylcarbazole (1), murrayafoline A (2), girinimbine (3), mahanimbine (4) and bicyclomahanimbine (5), were isolated for the first time from Clausena dunniana Levl. by bioassay-guided separation procedure and were identified by spectroscopic methods. Compounds 1-5 showed growth inhibitory activi...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602021000049041

    authors: Cui CB,Yan SY,Cai B,Yao XS

    更新日期:2002-12-01 00:00:00

  • The chemical constituents from Urtica fissa leaves.

    abstract::A new ceramide urticamide (1), two new secolignans urticalactones I (2) and Ⅱ (3), and a new flavonoid glycoside urticaside (4), together with 15 known compounds (4-19), were isolated from the leaves of Urtica fissa, a folk medicine for rheumatism arthritis in China. The active evaluation results showed that 1, 2, 3, ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1383397

    authors: Wang MY,Yang Y,Zhou XY,Wang SS,Duan SX,Li XB

    更新日期:2018-08-01 00:00:00

  • Alkaloids and sesquiterpenoids from Acorus tatarinowii.

    abstract::The rhizome of Acorus tatarinowii is a well-known traditional Chinese medicine. Our extensive investigation on this plant material afforded two new compounds, including a cadinane-type sesquiterpenoid and a pyrazine derivative, along with seven known compounds. The structures of the new compounds, tatarinowin B and ta...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.490522

    authors: Tong XG,Qiu B,Luo GF,Zhang XF,Cheng YX

    更新日期:2010-06-01 00:00:00

  • Two new acylgluconic acids from the nearly ripe fruits of Evodia rutaecarpa.

    abstract::Two new acylgluconic acids, trans-feruloylgluconic acid (1) and trans-caffeoylgluconic acid (2), together with three known compounds, myo-inositol (3), phthalic acid dibutyl ester (4), and wuzhuyuamide-I (5), were isolated from the water soluble part of the dried nearly ripe fruits of Evodia rutaecarpa (Juss.) Benth. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802031080

    authors: Zhao MY,Yang XW

    更新日期:2008-07-01 00:00:00

  • Two new xyloketals from the endophytic fungus Endomelanconiopsis endophytica derived from medicinal plant Ficus hirta.

    abstract::Chemical examination of the liquid culture of Endomelanconiopsis endophytica A326 isolated from the Chinese folk medicine Ficus hirta resulted in the isolation of two new xyloketals named xyloketals K and L (1-2) and three known analogs (3-5) including a new natural product (5). Their structures were determined on the...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1188084

    authors: Sun ZH,Liang FL,Chen YC,Liu HX,Li HH,Zhang WM

    更新日期:2016-11-01 00:00:00

  • Synthesis and cytotoxic activity of two steroids: icogenin aglycone analogs.

    abstract::During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell line...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1228633

    authors: Guan YY,Li SZ,Lei PS

    更新日期:2017-05-01 00:00:00

  • Four new triterpenoid saponins from Ardisia gigantifolia Stapf. and their cytotoxic activity.

    abstract::Four new oleanane-type triterpenoid saponins, cyclamiretin A 3beta-O-alpha-L-rhamnopyranosyl-(1 --> 3)-[beta-D-xylopyranosyl-(1 --> 2)]-beta-D-glucopyranosyl-(1 --> 4)-[beta-D-glucopyranosyl-(1 --> 2)]-alpha-L-arabinopyranoside (1), cyclamiretin A 3beta-O-alpha-L-rhamnopyranosyl-(1 --> 3)-[beta-D-glucopyranosyl-(1 -->...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802144719

    authors: Wen P,Zhang XM,Yang Z,Wang NL,Yao XS

    更新日期:2008-09-01 00:00:00

  • New triterpenoids from Arisaema jacquemontii.

    abstract::Phytochemical investigation of the roots of Arisaema jacquemontii led to the isolation of two new triterpenoids, which were characterized by NMR, IR, and MS spectra as 30-nor-lanost-5-ene-3beta-ol (1) and 30-norlanost-5-ene-3-one (2). ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020903505057

    authors: Jeelani S,Khuroo MA,Razadan TK

    更新日期:2010-02-01 00:00:00

  • Isoflavonoid glycosides from the flowers of Pueraria lobata.

    abstract::Pueraria lobata flower is a medicinal herb for treating intoxication, hepatic, and gastrointestinal tract lesions induced by alcohol. This study aims to investigate the isoflavonoid glycosides in P. lobata flowers. Two new isoflavone compounds were isolated from the extract of P. lobata flowers. Their structures were ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.554404

    authors: Yu YL,Liao YT,Li X,Ye Y,Ke CQ,Li XQ,Yang XZ,Yao MC

    更新日期:2011-04-01 00:00:00

  • Phytochemistry and insecticidal activity of Annona mucosa leaf extracts against Sitophilus zeamais and Prostephanus truncatus.

    abstract::A new oleanane type triterpene characterized as 3α, 24-diacetoxy-12-oleanene (1) together with known compounds 2-10, were isolated from Annona mucosa leaf extracts. Their structural elucidation was accomplished using physical and spectroscopic methods. The compounds showed weak to moderate insecticidal activities agai...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1818726

    authors: Makenzi AM,Manguro LOA,Owuor PO

    更新日期:2020-09-15 00:00:00

  • Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction.

    abstract::Pharmacochemistry and integrated pharmacokinetics of six alkaloids (groenlandicine, berberine, palmatine, epiberberine, jatrorrhizine, and columbamine) after oral administration of Huang-Lian-Jie-Du-Tang (HLJDT) decoction were investigated in this paper. The method of plasma pharmacochemistry was applied to predict th...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.913577

    authors: Ma ZT,Yang XW,Zhang Y,Liu JX

    更新日期:2014-01-01 00:00:00

  • Four new C10-polyacetylene glycosides from the rhizomes of Atractylodes lancea.

    abstract::An ongoing phytochemical investigation of the rhizomes of Atractylodes lancea resulted in the isolation of four new C10-type polyacetylene glycosides (1-4). Their structures were elucidated on the basis of extensive spectroscopic data (UV, IR, 1D and 2D NMR, and HRESIMS). The absolute configurations of compounds 2-4 w...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1247811

    authors: Xu K,Feng ZM,Yang YN,Jiang JS,Zhang PC

    更新日期:2017-02-01 00:00:00

  • Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra.

    abstract::A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sang...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1350653

    authors: Hu X,Yu MH,Yan GR,Wang HY,Hou AJ,Lei C

    更新日期:2018-05-01 00:00:00

  • New cycloartanes and new iridoids from Dolichandrone spathacea collected in the mangrove forest of Soc Trang province, Vietnam.

    abstract::Two new cycloartanes, named dolichandrone A (1) and dolichandrone B (2), as well as two new iridoids, named [6-O-[(E)-4-methoxycinnamoyl]-1β-hydroxy-dihydrocatalpolgenin (3) and 6-O-[(E)-4-methoxycinnamoyl]-1α-hydroxy-dihydrocatalpolgenin (4), together with four known iridoids (5-8), were isolated from the leaves and ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1406927

    authors: Nguyen VT,Do LQ,Nguyen TA,Nguyen TT,Tran VL,Ho NA,Tran VC,Tran VS,Tran TPT

    更新日期:2018-09-01 00:00:00

  • Two new sesquiterpene pyridine alkaloids from root barks of Celastrus angulatus.

    abstract::Two new sesquiterpene pyridine alkaloids, Chinese bittersweet alkaloid A (1) and Chinese bittersweet alkaloid B (2), together with five known compounds 3β- hydroxyolean-9(11),12-diene, β-sitosterol, 1β,2β,6α,15β-tetraacetoxy-8β,9α- dibenzoyloxy-β-dihydroagarofuran, angulatin A and angulatin J, were isolated from the r...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1492563

    authors: Chang X,Wang ZY,Chen X,Ma YN,Zhang HY,Zhao TZ

    更新日期:2019-11-01 00:00:00

  • Toxicokinetics and toxicity of potassium 2-(1-hydroxypentyl)-benzoate in beagle dogs.

    abstract::Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a prodrug of 3-n-butylphthalide (dl-NBP) for treatment of cerebral ischemic stroke in China, which undergoes lactonization to form dl-NBP in plasma. And, the phase II-III clinical trial of dl-PHPB has been approved by China Food and Drug Administration (CFDA) in 2013...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1302940

    authors: Li J,Wang XL,Wang AP,Xu SF,Jin HT

    更新日期:2017-04-01 00:00:00

  • Antioxidant compounds from ethanol extracts of bamboo (Neosinocalamus affinis) leaves.

    abstract::Activity-guided fractionation of Neosinocalamus affinis leaves led to obtain two new flavonoids, 4'-O-((7″R,8″S)-8″-guaiacylglyceryl)-pleioside B (9) and apigenin 6-C-β-d-fucopyranosyl-7-O-β-d-glucopyranoside (10) along with eight known compounds. Their structures were elucidated on the basis of spectroscopic data (UV...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.981164

    authors: Luo GY,Luo YG,Zhou R,Zhou M,Gu J,Ye Q,Dai Y,Zhang GL

    更新日期:2015-01-01 00:00:00

  • New phenethyl alcohol glycosides from Stachys parviflora.

    abstract::Phytochemical investigations of the whole plant of Stachys parviflora (Lamiaceae) resulted in the isolation of two new phenethyl alcohol glycosides. The structures of the new compounds named parviflorosides A and B were established as 2-(3,4-dihydroxyphenyl)-ethyl-O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-E-caffeoyl-bet...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500478708

    authors: Ahmad VU,Arshad S,Bader S,Ahmed A,Iqbal S,Tareen RB

    更新日期:2006-01-01 00:00:00

  • A new inositol derivative from Prenanthes macrophylla.

    abstract::A new chiro-inositol ester, 4-hydroxyphenylacetyl-3-d-chiro-inositol ester (1), was isolated from the whole plants of Prenanthes macrophylla Franch., along with 10 known compounds, 4-hydroxyphenylacetic acid (2), trans-ethyl caffeate (3), cis-ethyl caffeate (4), protocatechualdehyde (5), luteolin (6), luteolin-7-O-β-d...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.635142

    authors: Zhang YH,Chen YS,Lin XY,Chen SW,Li P,Zhong LJ

    更新日期:2012-01-01 00:00:00

  • Cytotoxic triterpenes from the acid hydrolyzate of Gynostemma pentaphyllum saponins.

    abstract::One new dammarane-type triterpene, gypsapogenin A (1), was isolated from the acid hydrolyzate of total saponins from Gynostemma pentaphyllum (Thunb.) Makino, together with two known compounds, (20S,24S)-3β,20,21β,23β,25-pentahydroxy-21,24-cyclodammarane (2) and (23S)-3β-hydroxydammar-20,24-dien-21-oic acid 21,23-lacto...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1322070

    authors: Shi L,Tan DH,Yan TC,Jiang DH,Hou MX

    更新日期:2018-02-01 00:00:00

  • (+)-Cyclopenol, a new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid from the fungus Penicillium sclerotiorum endogenous with the Chinese mangrove Bruguiera gymnorrhiza.

    abstract::One new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide C (5), viridicatin (6), 3-O-methylviridicatin (7), verrucosidin (8), ergoster...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.911290

    authors: Li J,Wang J,Jiang CS,Li G,Guo YW

    更新日期:2014-01-01 00:00:00

  • A new 3,4-seco-labdane diterpenoid with inhibitory activity against the production of nitric oxide from the leaves of Callicarpa nudiflora.

    abstract::A new 3,4-seco-labdane diterpenoid, 3,4-seco-12R,13S-dihydroxy-4(18),8(17),14(15)-labdatrien-3-oic acid (1), was isolated from the leaves of Callicarpa nudiflora. The structure of 1 was elucidated by 1D NMR, 2D NMR and HRESIMS data, and confirmed by single-crystal X-ray diffraction analysis. 3,4-seco-12R,13S-Dihydroxy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.841675

    authors: Zhang L,Liu MS,Huang J,Li GY,Zhang C,Dong L,Zhang K,Wang JH

    更新日期:2014-01-01 00:00:00

  • Synthesis, antitumor activity, and molecular docking of (-)-epigallocatechin-3-gallate-4β-triazolopodophyllotoxin conjugates.

    abstract::Two new (-)-epigallocatechin-3-gallate-4β-triazolopodophyllotoxin conjugates (7 and 8) were synthesized and evaluated for biological activity. Compound 8 showed highly potent anticancer activity against A-549 cell line with IC50 of 2.16 ± 1.02 μM, which displayed the highest selectivity index value (SI = 14.5) in A-54...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1786066

    authors: Zi CT,Yang L,Hu Y,Zhang P,Tang H,Zhang BL,Shen XJ,Kong QH,Wang Y,Wang XJ,Sheng J

    更新日期:2020-07-03 00:00:00

  • New tetraterpenoid from the soft coral Sarcophyton tortuosum.

    abstract::A novel tetraterpenoid named methyl tortuoate C (1) has been isolated from the soft coral Sarcophyton tortuosum Tix.-Dur. The structure of 1 was determined on the basis of spectroscopic methods. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020600604344

    authors: Lan WJ,Li HJ,Yan SJ,Su JY,Zeng LM

    更新日期:2007-04-01 00:00:00

  • Three new compounds from Dictamnus dasycarpus and their anti-inflammatory activities.

    abstract::Three new compounds (1-3), named dasycarine G (1), dasycarether (2), and dasycarester (3), along with seven known compounds (4-10) obtained from the genus Dictamnus for the first time, were isolated from the root bark of Dictamnus dasycarpus. Their structures were elucidated on the basis of spectroscopic data (UV, IR,...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2019.1620213

    authors: Gao P,Wang L,Zhao L,Zhang C,Zeng KW,Zhao MB,Zhang QY,Jiang Y,Tu PF,Guo XY

    更新日期:2020-08-01 00:00:00

  • Annonaceous acetogenins of the seeds from Annona muricata.

    abstract::Muricatenol (1) is a new C37 non-THF ring acetogenin with four hydroxyls and one isolated double bond in the long aliphatic chain. 2,4-cis-Gigantetrocinone (2) and 2,4-trans-gigantetrocinone (3) have been isolated as their acetates by preparative TLC. 2,4-trans-Isoannonacin-10-one (4) and 2,4-trans-isoannonacin (5) ha...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020108040366

    authors: Li DY,Yu JG,Zhu JX,Yu DL,Luo XZ,Sun L,Yang SL

    更新日期:2001-01-01 00:00:00

  • Thiophenes from Echinops latifolius.

    abstract::Six thiophenes were isolated and purified from ethanol extract of the roots of Echinops latifolius Tausch. Their structures were identified on the basis of spectral data. Among them, 5-(3-hydroxmethyl-3-isovaleroyloxyprop-1-ynyl)-2,2'-bithiophene (6) is a new compound, and 5-(3-hydroxy-4-isovaleroyloxybut-1-ynyl)-2,2'...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500176724

    authors: Wang Y,Li X,Meng DL,Li ZL,Zhang P,Xu J

    更新日期:2006-10-01 00:00:00

  • Two new phthalate derivatives from Nepeta clarkei (Labiatae).

    abstract::Two new phthalates bis(2-ethylundecyl)phthalate and bis(2-ethyltridecyl)phthalate have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei along with one known compound β-amyrin. The structures of the two new compounds and β-amyrin were assigned on the basis of their ¹H and ¹³C NMR s...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.620954

    authors: Hussain J,Rehman NU,Hussain H,Ali L,Al-Harrasi A

    更新日期:2012-01-01 00:00:00

  • Fasciospyrinadine, a novel sesquiterpene pyridine alkaloid from a Guangxi sponge Fasciospongia sp.

    abstract::Fasciospyrinadine (1), a novel sesquiterpene pyridine alkaloid with a previously unreported skeleton featuring a monocyclicfarnesane moiety attached to a 3-methylenepyridine residue, was isolated from the sponge Fasciospongia sp. from Weizhou Island, Guangxi Autonomous Region. The structure and the relative stereochem...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.751098

    authors: Zhao ZB,Sun JZ,Mao SC,Guo YW

    更新日期:2013-01-01 00:00:00