Antimicrobial acylphloroglucinols from the leaves of Rhodomyrtus tomentosa.

Abstract:

:Phytochemical study on the leaves of Rhodomyrtus tomentosa resulted in the isolation of fourteen compounds including a new acylphloroglucinol, named tomentosone C (1), and a new flavonol glycoside, namely myricetin-3,7,3'-trimethyl ether-5'-O-β-glucopyranoside (2). Their structures were characterized by spectral data interpretation for new structures and in comparison with published data for known compounds. The antimicrobial activity evaluation revealed that 1 and the known acylphloroglucinol rhodomyrtone (3) exhibited significant antimicrobial activity with MIC 3.66 and 1.83 μg ml(-1), respectively, toward Staphylococcus aureus, responsible for the antimicrobial activity observed with the n-hexane and EtOAc-soluble fraction of the ethanol extract of R. tomentosa leaves.

journal_name

J Asian Nat Prod Res

authors

Liu HX,Tan HB,Qiu SX

doi

10.1080/10286020.2015.1121997

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

535-41

issue

6

eissn

1028-6020

issn

1477-2213

journal_volume

18

pub_type

杂志文章
  • Four new minor taxanes from cell cultures of Taxus chinensis.

    abstract::Four new minor taxanes (1-4) have been isolated from Ts-19 cell cultures of Taxus chinensis together with five known taxanes (5-9) by silica gel chromatography combined with semi-preparative HPLC chromatography. On the basis of the analyses of the chemical and spectroscopic (IR, MS, 1D, and 2D NMR) data, the structure...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902882143

    authors: Xie D,Jia HT,Zhang Y,Zou JH,Yin DL,Chen XG,Yan YN,Dai JG

    更新日期:2009-06-01 00:00:00

  • A novel alkaloid from Huperzia crispate.

    abstract::A novel alkaloid, hupcrispatine (1), has been isolated from the unique Chinese species Huperzia crispate Ching. The structure of hupcrispatine has been elucidated as 9-amino-6-methyl-3-quinolone on the basis of spectral evidence. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802181448

    authors: Pei G,He GX,Du FL,Jiang DS

    更新日期:2008-09-01 00:00:00

  • Chemical constituents of the red alga Laurencia tristicha.

    abstract::Six new sesquiterpenes, 10-hydroxy-epiaplysin (1), 10-hydroxy-aplysin (2), 10-hydroxy-debromoepiaplysin (3), aplysin-9-ene (4), epiaplysinol (5) and debromoepiaplysinol (6), together with 13 known compounds (7-19), have been isolated from the red alga Laurencia tristicha. The structures of 1-6 were determined by spect...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020601103338

    authors: Sun J,Shi DY,Li S,Wang SJ,Han LJ,Fan X,Yang YC,Shi JG

    更新日期:2007-09-01 00:00:00

  • New xanthone glycosides from Securidaca inappendiculata.

    abstract::Three new xanthone glycosides, securixanside A (1), securixanside B (2), and securixanside C (3) were isolated from the stems of Securidaca inappendiculata. These compounds were characterized by spectrometric and chemical methods, including FABMS and one- and two-dimensional NMR experiments. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290027434

    authors: Yang XD,An N,Xu LZ,Yang SL

    更新日期:2002-06-01 00:00:00

  • Two new diterpenoid dimers, fritillebinide D and E, from bulbs of Fritillaria ebeiensis.

    abstract::Two new ent-kaurane diterpenoid dimers, fritillebinide D (1) and fritillebinide E (2), were isolated from bulbs of Fritillaria ebeiensis G.D. Yu et G.Q. Ji. Their structures have been determined to be ent-3beta-acetoxy-kauran-16beta, 17-acetal ent-3beta-acetoxy-16beta-kauran-17(R)-aldehyde (1) and ent-3beta-acetoxy-ka...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602021000049113

    authors: Ruan HL,Zhang YH,Wu JZ,Sun HD,Fujita T

    更新日期:2002-12-01 00:00:00

  • Coumarins from Peucedanum wulongense.

    abstract::A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-khellactone, was isolated from the root of Peucedanum wulongense. The structure of wulongensin A was established as 3'(R)-angelo...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000082034

    authors: Kong LY,Zhi F

    更新日期:2003-09-01 00:00:00

  • Andrographolide is neither a human organic anion transporter 1 (hOAT1) substrate nor inhibitor.

    abstract::Andrographolide, a major bioactive compound isolated from Andrographis paniculata (Burm. F.) Nees, was evaluated for its effects on the hOAT1 membrane transporter. Substrate determination and inhibition of hOAT1-mediated uptake transport assay was carried out using recombinant CHO-hOAT1 cells. The results showed that ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1520704

    authors: Chong YM,Kaur G,Tan ML

    更新日期:2019-08-01 00:00:00

  • A new cycloartane glycoside from Comptosorus sibiricus rupr.

    abstract::The structure of a new cycloartane glycoside isolated from the whole herbs of Comptosorus sibiricus Rupr. has been established, by chemical and spectroscopic methods (IR, 1D and 2D NMR, HRMS, ESI-MS), as 3beta,7beta,24beta,25,30-pentahydroxycycloartane 24-O-beta-D-glucopyranoside (1). ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020310001617183

    authors: Li N,Li X,Ma ZJ,Wang JH

    更新日期:2005-04-01 00:00:00

  • Four new koumine metabolites in rat liver microsomes.

    abstract::Four new metabolites M-1 [1,2,18,19-tetradehydro-4-demethyl-3,17-epoxy-7,20(2H,19H)-cyclovobasan], M-2 [1,2,4,21,18,19-hexadehydro-4-demethyl-3,17-epoxy-7,20(2H,19H)-cyclovobasan], M-3 [1,2,18,19-tetradehydro-4-demethyl-4-formaldehyde-3,17-epoxy-7,20(2H,19H)-cyclovobasan], and M-4 [1,2,4,21,18,19-hexadehydro-4-demethy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.742511

    authors: Zhang L,Du L,Lv WW,Zhao QC,Hua W,An Y,Guo T,Wu LJ

    更新日期:2013-01-01 00:00:00

  • Effect of corchorusin-D, a saikosaponin like compound, on B16F10 melanoma cells (in vitro and in vivo).

    abstract::Corchorusin-D (COR-D), isolated from Corchorus acutangulus, was reported to induce apoptosis in leukemic cells. However, no studies concerning its activity on melanoma cells have been reported. We have evaluated its in vitro anti-cancer activity on melanoma cells (B16F10, SK-MEL-28, and A375). The results demonstrate ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.837451

    authors: Mallick S,Pal BC,Kumar D,Chatterjee N,Das S,Saha KD

    更新日期:2013-11-01 00:00:00

  • A novel phenolic compound from Pinus yunnanensis.

    abstract::A rare type of phenolic compound, namely, planchol E (1), was isolated from the cones and seeds of Pinus yunnanensis together with 16 known abietane diterpenoids (2-17). The structure of planchol E was established on the basis of extensive spectroscopic analysis, and it was found that the new compound did not show cyt...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.565747

    authors: Lei T,Li Y,Li DM,Liu GM,Liu JK,Wang F

    更新日期:2011-05-01 00:00:00

  • A new bioactive coumestan from the seeds of Psoralea corylifolia.

    abstract::A new coumestan named bavacoumestan D (1), together with five known compounds (2-6), was isolated from EtOAc-soluble extract of seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All compounds were evaluated for in vitro inhibitory activity agai...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1563073

    authors: Chai MY

    更新日期:2020-03-01 00:00:00

  • Synthesis of (+)-lariciresinol 3a-acetate, a lignan from Aglaia elaeagnoidea.

    abstract::(+)-Lariciresinol 3a-acetate [(+)-(3S)-acetyloxymethyl-(2S)-(4-hydroxy-3-methoxyphenyl)-(4R)-[(4-hydroxy-3-methoxyphenyl)methyl]tetrahydrofuran] (1), a metabolite of A. elaeagnoidea was synthesized starting from (-)-lariciresinol (2) in three steps with an overall yield of 66%. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020008039904

    authors: Rajasekhar D,Subbaraju GV

    更新日期:2000-01-01 00:00:00

  • Monoterpenes and sesquiterpenes from the marine sediment-derived fungus Eutypella scoparia FS46.

    abstract::Eutypellol A (1), the first norsesquiterpenoid of sequicarene family, as well as eutypellol B (2), a rare 7-methyl oxidized 2-carene derivative, and one new natural product 2-(2-hydroxy-4-methylcyclohex-3-enyl)propanoic acid (3), along with eight known terpenoids, were isolated from the marine sediment-derived fungus ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1189906

    authors: Liu HX,Zhang L,Chen YC,Sun ZH,Pan QL,Li HH,Zhang WM

    更新日期:2017-02-01 00:00:00

  • Two new abietane diterpenoids from the leaves of Rabdosia serra.

    abstract::Phytochemical investigation on the leaves of Rabdosia serra led to the isolation of two new abietane diterpenoids, raserranes A (1) and B (2), and four known phenylpropanoids (3-6). Their structures were determined by spectroscopic data. Compound 1 represented the rare examples of abietane diterpenoids featuring a 16-...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1539081

    authors: Liu GL,Xu W,Liu XJ,Yan XL,Chen J

    更新日期:2020-01-01 00:00:00

  • Bromophenols from the brown alga Leathesia nana.

    abstract::Two new bromophenols, (E)-3-(2,3-dibromo-4,5-dihydroxyphenyl)-2-methylpropenal (1) and 3-(2,3-dibromo-4,5-dihydroxyphenyl)-2-methyl-1-propanol (2), together with 11 known bromophenols (3-13), were isolated from the ethanolic extract of the brown alga Leathesia nana S. et G. Their structures have been elucidated by spe...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020310001653273

    authors: Xu XL,Fan X,Song FH,Zhao JL,Han LJ,Yang YC,Shi JG

    更新日期:2004-09-01 00:00:00

  • Toxicokinetics and toxicity of potassium 2-(1-hydroxypentyl)-benzoate in beagle dogs.

    abstract::Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) is a prodrug of 3-n-butylphthalide (dl-NBP) for treatment of cerebral ischemic stroke in China, which undergoes lactonization to form dl-NBP in plasma. And, the phase II-III clinical trial of dl-PHPB has been approved by China Food and Drug Administration (CFDA) in 2013...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1302940

    authors: Li J,Wang XL,Wang AP,Xu SF,Jin HT

    更新日期:2017-04-01 00:00:00

  • Two new 2-phenylethylchromones from artificial agarwood by holing method.

    abstract::Two new 2-(2-phenylethyl)chromone derivatives (1-2) were isolated from the ethyl acetate extract of artificial agarwood induced by holing method originating from Aquilaria sinensis (Lour.) Gilg, and they were isolated from this genus for the first time. The structures of these two new compounds were elucidated by exte...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1860029

    authors: Xiang P,Zeng YB,Wang H,Kong FD,Chen HQ,Mei WL,Dai HF

    更新日期:2020-12-18 00:00:00

  • Flavone c-glycosides from Trollius ledebouri reichb.

    abstract::A new acylated C-glycosylflavone (1) was isolated from Trollius ledebouri Reichb together with two known C-glycosyflavones (2, 3). The structures were elucidated by spectroscopic methods, including HRMS, IR, 1H and 13C NMR and 2D experiments (COSY, HMQC and HMBC). The anti-inflammatory activities of 1-3 were tested on...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500176922

    authors: Wu XA,Zhao YM,Yu NJ

    更新日期:2006-09-01 00:00:00

  • Two new compounds from Aconitum tanguticum.

    abstract::A phytochemical investigation on the whole plant of Aconitum tanguticum (Ranunculaceae) resulted in the isolation and characterization of two new phenylpropanoid glycosides (1 and 2). Their structures were elucidated as 4-hydroxyphenethoxy-8-O-β-d-[6-O-(4-O-β-d-glucopyranosyl)-sinapoyl]-glucopyranoside (1) and 3,4-dim...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.904292

    authors: Li YR,Xu L,Li C,Wang ZM,Yang LX

    更新日期:2014-01-01 00:00:00

  • Phytochemistry and insecticidal activity of Annona mucosa leaf extracts against Sitophilus zeamais and Prostephanus truncatus.

    abstract::A new oleanane type triterpene characterized as 3α, 24-diacetoxy-12-oleanene (1) together with known compounds 2-10, were isolated from Annona mucosa leaf extracts. Their structural elucidation was accomplished using physical and spectroscopic methods. The compounds showed weak to moderate insecticidal activities agai...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1818726

    authors: Makenzi AM,Manguro LOA,Owuor PO

    更新日期:2020-09-15 00:00:00

  • Selaginellin M, a new selaginellin derivative from Selaginella pulvinata.

    abstract::A new selaginellin derivative, selaginellin M (1), together with one known compound, selaginellin E (2), was isolated from Selaginella pulvinata. The structure of the new compound was elucidated and named as (R,S)-4-((4'-hydroxy-4-((2-hydroxyethoxy)methyl))-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)me...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.617304

    authors: Xu KP,Zou H,Liu GR,Long HP,Li J,Li FS,Zou ZX,Kuang JW,Xie X,Tan GS

    更新日期:2011-10-01 00:00:00

  • Novel ursane-type triterpene from the fresh leaves of Carissa carandas and evaluation of cytotoxicity.

    abstract::One novel ursolic acid derivative sabiracin 1 (11,25-epoxy-3β-hydroxy-urs-12-en-28-oic acid) was isolated from the leaves of Carissa carandas, together with five known compounds para hydroxy benzaldehyde (2), ursolic acid (3), carissin (4), 22α-hydroxyursolic acid (5) and β-sitosterol-3-O-β-D-glucopyranoside (6). Comp...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1791098

    authors: Bano Z,Begum S,Ali SS,Kiran Z,Siddiqui BS,Khawaja S,Ahmed A

    更新日期:2020-07-10 00:00:00

  • Chemical constituents from the roots of Ranunculus ternatus.

    abstract::Two new glycosides named as ternatoside A (1) and ternatoside B (2), with four known constituents sternbin (3), methylparaben (4), 4-O-D-glucopyranosyl-p-coumaric acid (5) and linocaffein (6) were isolated from the roots of Ranunculus ternatus, The structures of new compounds were determined by 1D and 2D NMR, MS techn...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500385663

    authors: Tian JK,Sun F,Cheng YY

    更新日期:2006-01-01 00:00:00

  • Constituents from the roots of Heracleum rapula Franch.

    abstract::A new coumarin glucoside, 8-hydroxy-5-O-beta-D-glucosylpsoralen, along with 17 known coumarins and one steroid, was isolated from the roots of Heracleum rapula Franch. Four coumarin glucosides, including the new one, were obtained from the water-soluble fraction. The other coumarins isolated from the ethyl acetate-fra...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290019677

    authors: Niu XM,Li SH,Jiang B,Zhao QS,Sun HD

    更新日期:2002-03-01 00:00:00

  • Bioactive phenolics from Seriphidium stenocephalum.

    abstract::Chromatographic separation of the ethyl acetate soluble part of the methanolic extract from Seriphidium stenocephalum yielded three new compounds: stenocepflavone (1), stenocepflavan (2), and stenocephol (3), together with cirsimaritin (4), 5,7,5'-trihydroxy-3',4',6-trimethoxyflavone (5), 5,6,7,5'-tetrahydroxy-4'-meth...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.763226

    authors: Shafiq N,Riaz N,Ahmed S,Ashraf M,Ejaz SA,Ahmed I,Saleem M,Touseef MI,Tareen RB,Jabbar A

    更新日期:2013-01-01 00:00:00

  • Tomentodione E, a new sec-pentyl syncarpic acid-based meroterpenoid from the leaves of Rhodomyrtus tomentosa.

    abstract::A new meroterpenoid, tomentodione E (1), along with four known ones (2-5) were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated based on extensive spectroscopic data as well as computational methods. Compound 1 represents the first example of meroterpenoid possessing a sec-pentyl syn...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1318852

    authors: Liu J,Song JG,Su JC,Huang XJ,Ye WC,Wang Y

    更新日期:2018-01-01 00:00:00

  • Microbial hydroxylation of cinobufagin by Mucor spinosus.

    abstract::Mucor spinosus has been employed for the biotransformation of cinobufagin (1) to afford three metabolites. On the basis of their physico-chemical data, the structures of the transformation products have been characterized as 1beta-hydroxy-cinobufagin (2), 12beta-hydroxy-cinobufagin (3) and 1beta,12beta-dihydroxy-cinob...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020410001690136

    authors: Zhang W,Ye M,Qu GQ,Wu WY,Chen YJ,Guo DA

    更新日期:2005-06-01 00:00:00

  • Two new indole alkaloids from Nauclea officinalis.

    abstract::Two new indole alkaloids, naucleactonin A and B, along with two known compounds, naucleficine and nauclefidine, were isolated from the bark and wood of Naucleaofficinalis, which has been used as an anti-inflammatory and anti-bacterial agent in folk medicine. Their chemical structures were elucidated by the spectral da...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500246741

    authors: Xuan WD,Chen HS,Du JL,Liang S,Li TZ,Cai DG

    更新日期:2006-12-01 00:00:00

  • Triterpene saponins from the leaves of Ilex kudingcha.

    abstract::Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902937491

    authors: Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

    更新日期:2009-06-01 00:00:00