Tomentodione E, a new sec-pentyl syncarpic acid-based meroterpenoid from the leaves of Rhodomyrtus tomentosa.

Abstract:

:A new meroterpenoid, tomentodione E (1), along with four known ones (2-5) were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated based on extensive spectroscopic data as well as computational methods. Compound 1 represents the first example of meroterpenoid possessing a sec-pentyl syncarpic acid motif coupled with a caryophyllene. Compounds 1-4 were evaluated for their in vitro antiviral activity against respiratory syncytial virus (RSV) with cytopathic effect (CPE) reduction assay, and 2 showed potent in vitro anti-RSV effect.

journal_name

J Asian Nat Prod Res

authors

Liu J,Song JG,Su JC,Huang XJ,Ye WC,Wang Y

doi

10.1080/10286020.2017.1318852

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

67-74

issue

1

eissn

1028-6020

issn

1477-2213

journal_volume

20

pub_type

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