New C-19-modified geldanamycin derivatives: synthesis, antitumor activities, and physical properties study.

abstract：:Two new cycloartanes, named dolichandrone A (1) and dolichandrone B (2), as well as two new iridoids, named [6-O-[(E)-4-methoxycinnamoyl]-1β-hydroxy-dihydrocatalpolgenin (3) and 6-O-[(E)-4-methoxycinnamoyl]-1α-hydroxy-dihydrocatalpolgenin (4), together with four known iridoids (5-8), were isolated from the leaves and ...

journal_title：Journal of Asian natural products research

authors： Nguyen VT,Do LQ,Nguyen TA,Nguyen TT,Tran VL,Ho NA,Tran VC,Tran VS,Tran TPT

更新日期：2018-09-01 00:00:00

abstract：:Ten (1-10) irritant and mild co-carcinogenic diterpene esters were isolated from the latex of Euphorbia cauducifolia L. using bioassay-guided countercurrent distribution and other chromatographic techniques. The isolated compounds were characterized on the basis of spectroscopic results and mass measurements. As an ou...

journal_title：Journal of Asian natural products research

authors： Baloch IB,Baloch MK

更新日期：2010-07-01 00:00:00

abstract：:One novel ursolic acid derivative sabiracin 1 (11,25-epoxy-3β-hydroxy-urs-12-en-28-oic acid) was isolated from the leaves of Carissa carandas, together with five known compounds para hydroxy benzaldehyde (2), ursolic acid (3), carissin (4), 22α-hydroxyursolic acid (5) and β-sitosterol-3-O-β-D-glucopyranoside (6). Comp...

journal_title：Journal of Asian natural products research

authors： Bano Z,Begum S,Ali SS,Kiran Z,Siddiqui BS,Khawaja S,Ahmed A

更新日期：2020-07-10 00:00:00

abstract：:Six new sesquiterpenes, 10-hydroxy-epiaplysin (1), 10-hydroxy-aplysin (2), 10-hydroxy-debromoepiaplysin (3), aplysin-9-ene (4), epiaplysinol (5) and debromoepiaplysinol (6), together with 13 known compounds (7-19), have been isolated from the red alga Laurencia tristicha. The structures of 1-6 were determined by spect...

journal_title：Journal of Asian natural products research

authors： Sun J,Shi DY,Li S,Wang SJ,Han LJ,Fan X,Yang YC,Shi JG

更新日期：2007-09-01 00:00:00

abstract：:Two new flavonoid alkaloids, 8-(2''-pyrrolidinone-5''-yl)-quercetin (1) and 8-(2''-pyrrolidinone-5''-yl)-isorhamnetin (2), were isolated from the herb of Senecio argunensis. Their structures were elucidated by spectral analysis. ...

journal_title：Journal of Asian natural products research

authors： Li N,Shao L,Zhang CF,Zhang M

更新日期：2008-11-01 00:00:00

abstract：:A bioassay-guided phytochemical fractionation of the methanol extract of the Morus alba root barks led to the isolation of two chalcone-derived Diels-Alder adducts (1 and 2). Their structures were elucidated as kuwanon J 2,4,10″-trimethyl ether (1) and kuwanon R (2) by means of spectroscopic methods. Both compounds st...

journal_title：Journal of Asian natural products research

authors： Phung TX,Tran TH,Dan TT,Chau VM,Hoang TH,Nguyen TD

更新日期：2012-01-01 00:00:00

abstract：:3,7-Dimethyl-7-hydroxy-2-octen-1,6-olide and 3,7-dimethyl-2,6-octadien-1,6-olide, the natural bioactive compounds isolated from the fruit of Litsea cubeba and the liverwort Plagiochila rutilans, were totally synthesized using easily available cis-geraniol as raw material in short, convenient, and low-cost, five-step r...

journal_title：Journal of Asian natural products research

authors： Dong HB,Yang MY,Jiang JZ,Wang MA

更新日期：2013-01-01 00:00:00

abstract：:A novel oxybis cresol compound named verticilatin (1), together with two known compounds, 5-methylresorcinol (2) and 2,4-dihydroxy-3,6-dimethylbenzaldehyde (3), was isolated from cultures of the insect pathogenic fungi Paecilomyces verticillatus. The structures of compounds were determined by extensive spectroscopic a...

journal_title：Journal of Asian natural products research

authors： Wei PY,Li L,Yang CG,Luo DQ,Zheng ZH,Lu XH,Shi BZ

更新日期：2014-12-01 00:00:00

abstract：:Enterovirus 71 (EV71) is a huge threat to the worldwide public health and there is no approved antiviral drug for EV71-induced disease therapy. Corydaline exists antiallergic and antinociceptive activities, but the anti-EV71 activity of corydaline is still not reported. In this study, corydaline could suppress the exp...

journal_title：Journal of Asian natural products research

authors： Wang HQ,Hu J,Yan HY,Wu S,Li YH

更新日期：2017-11-01 00:00:00

abstract：:A phytochemical study on the seeds of Cassia obtusifolia was carried out, which finally led to obtain two naphthalenes (1 and 2), two naphthopyrans (3 and 4) and twelve anthraquinones (5-16). The structures of all compounds were established mainly by NMR and MS experiments as well as the necessary chemical evidence. A...

journal_title：Journal of Asian natural products research

authors： Pang X,Li NN,Yu HS,Kang LP,Yu HY,Song XB,Fan GW,Han LF

更新日期：2019-10-01 00:00:00

abstract：:Phytochemical investigation on the whole plants of Iris japonica led to the isolation of four new aromatic glycosides. Their structures including the absolute configurations were determined by spectroscopic and chemical methods as (-)-4-hydroxy-3-methoxy acetophenone 4-O-β-d-{6-O-[4-O-(7R,8S)-(4-hydroxy-3-methoxypheny...

journal_title：Journal of Asian natural products research

authors： Shi GR,Wang X,Liu YF,Zhang CL,Wang Y,Li L,Ni G,Chen RY,Yu DQ

更新日期：2016-10-01 00:00:00

abstract：:Two new apianen lactones, named as guanyeliaoine I (1) and guanyeliaoine II (2), have been isolated along with seven known compounds from Polygonum perforliatum L. (Chinese name "Guanyeliao", Berberidaceae). Their structures were deduced on the basis of spectral data and chemical methods. ...

journal_title：Journal of Asian natural products research

authors： Shen T,Jia ZJ,Zheng SZ

更新日期：2007-03-01 00:00:00

abstract：:Two new diterpenoid glycosides, fructusnoids D (1) and E (2), and two new monoterpenoid glycosides (3, 4), together with three known diterpenoid glycosides (5-7) and three known monoterpenoid glycosides (8-10), were isolated from the fruits of Xanthium chinense. Their structures were elucidated by spectrometric analys...

journal_title：Journal of Asian natural products research

authors： Cheng Y,Fu J,Chen L,Li LL,Qu J

更新日期：2019-03-01 00:00:00

abstract：:Podophyllotoxin and its synthetic derivatives are valuable medicinal agents that have antitumor, insecticidal, and antifungal properties. We previously synthesized a deoxypodophyllotoxin derivative with an opened D-ring (DPD) exhibiting potent insecticidal activity. This article was firstly performed to identify the c...

journal_title：Journal of Asian natural products research

authors： Chen C,Wang CC,Wang Z,Geng WY,Xu H,Song XM,Luo DQ

更新日期：2016-05-01 00:00:00

abstract：:Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂, and ginsenoside Rh₁₃. Their structures were elucidated as (20S)-3β,6α,12β,20-tetrahydroxydammara-25-ene-2...

journal_title：Journal of Asian natural products research

authors： Liu GY,Li XW,Wang NB,Zhou HY,Wei W,Gui MY,Yang B,Jin YR

更新日期：2010-10-01 00:00:00

abstract：:Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extr...

journal_title：Journal of Asian natural products research

authors： Su SS,Tian L,Chen G,Li ZQ,Xu WF,Pei YH

更新日期：2013-01-01 00:00:00

abstract：:A new diimide derivative, named (-)-byssochlamic acid bisdiimide (1), was isolated from the mixed broth of two mangrove fungi (strain no. K38 and E33) from the South China sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, including 1D and 2D NMR (COSY, HMQC, and HMBC) and semi-synthe...

journal_title：Journal of Asian natural products research

authors： Li CY,Ding WJ,Shao CL,She ZG,Lin YC

更新日期：2010-09-01 00:00:00

abstract：:Three new compounds named tanshinoic acid A (1), tanshinoic acid B (2), and tanshinoic acid C (3) were isolated from the rhizomes of Salvia miltiorrhiza, together with two known compounds methyl salvianolate A (4) and methyl salvianolate C (5). Their structures were determined on the basis of spectroscopic data (UV, I...

journal_title：Journal of Asian natural products research

authors： Gu QC,Yin ZK,Feng ZM,Jiang JS,Zhang X,Zhang PC,Yang YN

更新日期：2020-10-01 00:00:00

abstract：:A new triterpenoid saponin named clematichinenoside AR(2), along with the six known compounds, was isolated and characterized from Clematis chinensis Osbeck (Ranunculaceae), a commonly used traditional Chinese medicine with anti-inflammatory and anti-rheumatoid activities. The structure of the new saponin was elucidat...

journal_title：Journal of Asian natural products research

authors： Liu LF,Ma XL,Wang YX,Li FW,Li YM,Wan ZQ,Tang QL

更新日期：2009-01-01 00:00:00

abstract：:Two new benzo[de]isoquinoline derivatives, 4-phenyl-benzo[de]isoquinoline-1,3-dione (1) and 4-(4-hydroxyphenyl)-benzo[de]isoquinoline-1,3-dione (2), were isolated from 70% ethanol extract of the rhizomes of Musa basjoo. Their chemical structures were elucidated by HRESIMS, 1 D and 2 D spectra. ...

journal_title：Journal of Asian natural products research

authors： Ma X,Jiang L,Zhu MH,Liu CH,Wang GC,Li YT,Liu T,Li YJ

更新日期：2021-01-19 00:00:00

abstract：:Two new quinochalcone glycosides, hydroxysafflor yellow A-4'-O-β-D-glucopyranoside (1) and 3'-hydroxyhydroxysafflor yellow A (2), were isolated from the safflower yellow pigments of Carthamus tinctorius. The structures of new compounds were elucidated by a detailed spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D ...

journal_title：Journal of Asian natural products research

authors： Zhang H,Duan CP,Luo X,Feng ZM,Yang YN,Zhang X,Jiang JS,Zhang PC

更新日期：2020-12-01 00:00:00

abstract：:We present the synthesis of enantiomerically pure (S)-α-methyl-serine methyl ester hydrochloride from 2-methyl-3-((4-(trifluoromethyl)benzyl)oxy)propanal and di-p-chlorobenzyl azodicarboxylate via asymmetrically catalyzed amination with naphthylalanine derivative catalyst. The application of the organocatalyst of D-3-...

journal_title：Journal of Asian natural products research

authors： Xiao Q,Tang YF,Xie P

更新日期：2020-01-01 00:00:00

abstract：:A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR. ...

journal_title：Journal of Asian natural products research

authors： Chen Z,Liu YL,Xu QM,Liu JY,Duan HQ,Yang SL

更新日期：2013-01-01 00:00:00

abstract：:Fasciospyrinadine (1), a novel sesquiterpene pyridine alkaloid with a previously unreported skeleton featuring a monocyclicfarnesane moiety attached to a 3-methylenepyridine residue, was isolated from the sponge Fasciospongia sp. from Weizhou Island, Guangxi Autonomous Region. The structure and the relative stereochem...

journal_title：Journal of Asian natural products research

authors： Zhao ZB,Sun JZ,Mao SC,Guo YW

更新日期：2013-01-01 00:00:00

abstract：:Phytochemical study on the leaves of Rhodomyrtus tomentosa resulted in the isolation of fourteen compounds including a new acylphloroglucinol, named tomentosone C (1), and a new flavonol glycoside, namely myricetin-3,7,3'-trimethyl ether-5'-O-β-glucopyranoside (2). Their structures were characterized by spectral data ...

journal_title：Journal of Asian natural products research

authors： Liu HX,Tan HB,Qiu SX

更新日期：2016-06-01 00:00:00

abstract：:Two new anthraquinones, methyl 8-hydroxy-3-methoxy-6,7-methylenedioxy-1-methylanthraquinone-2-carboxylate (gandavensin A, 1) and methyl 8-hydroxy-3,6,7-trimethoxy-1-methylanthraquinone-2-carboxylate (gandavensin B, 2), have been isolated from the light petroleum extract of the subterranean corm of Gladiolus gandavensi...

journal_title：Journal of Asian natural products research

authors： Wang DY,Ye Q,Zhang GL,Li BG

更新日期：2003-12-01 00:00:00

abstract：:Three new iridoids, named artselaenin I, II and III, were isolated from the whole plants of Pedicularis artselaeri, along with 11 known compounds, 8-epiloganic acid, 7-deoxy-8-epiloganic acid, plantarenaloside, mussaenoside, lariciresinol-4-O-beta-D-glucoside, lariciresinol-4'-O-beta-D-glucoside, alaschaniosideA, cirt...

journal_title：Journal of Asian natural products research

authors： Su BN,Zhai JJ,Jia ZJ

更新日期：1998-01-01 00:00:00

abstract：:Two new cycloartane glycosides were isolated from the aerial parts of Thalictrum fortunei (Ranunculaceae). The chemical structures of these compounds were elucidated as 3-O-β-D-glucopyranosyl (1 → 4)-β-d-fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,30-tetraol 26-O-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl (1 →...

journal_title：Journal of Asian natural products research

authors： Zhang XT,Ma SW,Jiao HY,Zhang QW

更新日期：2012-01-01 00:00:00

abstract：:A series of piplartine derivatives were synthesized via Baylis-Hillman reaction and evaluated for anticancer and antibacterial activities. The cytotoxicity of these compounds was examined in two different human tumor cell lines, IMR-32 and HeLa. The antibacterial activity was examined in Staphylococcus aureus and Pseu...

journal_title：Journal of Asian natural products research

authors： Kumar JU,Shankaraiah G,Kumar RS,Pitke VV,Rao GT,Poornima B,Babu KS,Sreedhar AS

更新日期：2013-01-01 00:00:00

abstract：:Pharmacologically motivated natural product investigations have yielded a large variety of structurally unique lead compounds with interesting biomedical properties, but the natural roles of these molecules often remain unknown. In the present investigation, a series of benzyl substituted-flavone derivatives have been...

journal_title：Journal of Asian natural products research

authors： Kumar GS,Tiwari AK,Rao VR,Prasad KR,Ali AZ,Babu KS

更新日期：2010-11-01 00:00:00