解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Mangrove endophytic fungi were proved to be a prolific resources for bioactive secondary metabolites. Two new polyketides, pestalotiopin B (1) and pestalotiopyrone N (2) were obtained from the ethyl acetate extracts of the rice solid cultures of the mangrove endophytic fungus Pestalotiopsis sp. HQD-6. The structures o...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2021.1877674
更新日期:2021-01-29 00:00:00
abstract::Two new benzo[de]isoquinoline derivatives, 4-phenyl-benzo[de]isoquinoline-1,3-dione (1) and 4-(4-hydroxyphenyl)-benzo[de]isoquinoline-1,3-dione (2), were isolated from 70% ethanol extract of the rhizomes of Musa basjoo. Their chemical structures were elucidated by HRESIMS, 1 D and 2 D spectra. ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2021.1871604
更新日期:2021-01-19 00:00:00
abstract::One pair of new amides enantiomers (1a and 1b) and two known amides were isolated from the rhizomes of Polygonum cuspidatum. Their structures were established using UV, IR, HRESIMS, and NMR data. Notably, compound 1 possesses unique C-C connection between feruloyltyramine and resveratrol. Their absolute configurations...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2021.1873298
更新日期:2021-01-18 00:00:00
abstract::Two new 2-(2-phenylethyl)chromone derivatives (1-2) were isolated from the ethyl acetate extract of artificial agarwood induced by holing method originating from Aquilaria sinensis (Lour.) Gilg, and they were isolated from this genus for the first time. The structures of these two new compounds were elucidated by exte...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1860029
更新日期:2020-12-18 00:00:00
abstract::Two new quinochalcone glycosides, hydroxysafflor yellow A-4'-O-β-D-glucopyranoside (1) and 3'-hydroxyhydroxysafflor yellow A (2), were isolated from the safflower yellow pigments of Carthamus tinctorius. The structures of new compounds were elucidated by a detailed spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1846530
更新日期:2020-12-01 00:00:00
abstract::Three new compounds named tanshinoic acid A (1), tanshinoic acid B (2), and tanshinoic acid C (3) were isolated from the rhizomes of Salvia miltiorrhiza, together with two known compounds methyl salvianolate A (4) and methyl salvianolate C (5). Their structures were determined on the basis of spectroscopic data (UV, I...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1799988
更新日期:2020-10-01 00:00:00
abstract::A new oleanane type triterpene characterized as 3α, 24-diacetoxy-12-oleanene (1) together with known compounds 2-10, were isolated from Annona mucosa leaf extracts. Their structural elucidation was accomplished using physical and spectroscopic methods. The compounds showed weak to moderate insecticidal activities agai...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1818726
更新日期:2020-09-15 00:00:00
abstract::Three new decenynol glucosides were isolated from the aerial parts of Artemisia scoparia. Their structures were determined to be 6E,8Z-decadien-4-yn-ol 1-O-β-d-glucopyranoside, 6E,8E-decadien-4-yn-ol 1-O-β-d-glucopyranoside, and 6E-decen-4-yn-ol 1-O-β-d-glucopyranoside based on extensive spectroscopic (NMR and MS) ana...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1646729
更新日期:2020-09-01 00:00:00
abstract::A new prenylated coumarin diglycoside, 6-prenylcoumarin-7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (1) and five known flavonoid glycosides (2-6) were isolated from the leaves and stems of Clausena dunniana. The structures of these isolates were elucidated based on comprehensive MS, UV, IR, and NMR spectroscopic d...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1810671
更新日期:2020-08-30 00:00:00
abstract::Three new compounds (1-3), named dasycarine G (1), dasycarether (2), and dasycarester (3), along with seven known compounds (4-10) obtained from the genus Dictamnus for the first time, were isolated from the root bark of Dictamnus dasycarpus. Their structures were elucidated on the basis of spectroscopic data (UV, IR,...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1620213
更新日期:2020-08-01 00:00:00
abstract::Three new compounds, namely massonside C (1), massonianoside F (2), and 3, 8-dimethyl- herbacetin-7-O-β-D-glucopyranoside (3), together with five known compounds (4-8), were isolated from the fresh needles of Pinus massoniana. Their structures were established by 1D, 2D NMR, HRMS and comparison with the literature dat...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1642331
更新日期:2020-08-01 00:00:00
abstract::One novel ursolic acid derivative sabiracin 1 (11,25-epoxy-3β-hydroxy-urs-12-en-28-oic acid) was isolated from the leaves of Carissa carandas, together with five known compounds para hydroxy benzaldehyde (2), ursolic acid (3), carissin (4), 22α-hydroxyursolic acid (5) and β-sitosterol-3-O-β-D-glucopyranoside (6). Comp...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1791098
更新日期:2020-07-10 00:00:00
abstract::Two new (-)-epigallocatechin-3-gallate-4β-triazolopodophyllotoxin conjugates (7 and 8) were synthesized and evaluated for biological activity. Compound 8 showed highly potent anticancer activity against A-549 cell line with IC50 of 2.16 ± 1.02 μM, which displayed the highest selectivity index value (SI = 14.5) in A-54...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1786066
更新日期:2020-07-03 00:00:00
abstract::A seco-apotirucallane-type triterpenoid, namely angustifolianin (1), along with three dammarane-type triterpenoids, (20S, 24S)-epoxy-dammarane-3β,25-diol (2), 3-epi-cabraleahydroxylactone (3), and cabralealactone (4), were isolated from the stem bark of Aglaia angustifolia Miq. The Chemical structure of the new compou...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1776704
更新日期:2020-06-13 00:00:00
abstract::A total of 15 novel-substituted 3-(benzylsulfanyl)-1H-1,2,4-triazol-5-ylamine and 10 novel-substituted 3-benzylmercapto-1,2,4-triazol derivatives were synthesized based on the natural product phenazine-1-carboxylic acid (PCA). Their structures were confirmed by 1H-NMR, 13C-NMR, HRMS, and X-ray. Most substituted 3-benz...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1754400
更新日期:2020-05-07 00:00:00
abstract::A series of aromatic or long-chain chrysin derivatives (1-10) were synthesized by esterification of chrysin and acyl chloride. The chemical structures of these compounds were determined by mass spectrum (MS), 1H NMR, and 13C NMR spectra. Though aromatic chrysin derivatives (1-9) with a rigid structure were hard to dis...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1586677
更新日期:2020-05-01 00:00:00
abstract::A new prenylated coumarin (1) and a new anthranilamide derivative (2) were isolated from the aerial parts of Evodia lepta. Compound 2 represents the first anthranilamide derivative from the Evodia genus. Their structures were elucidated by spectroscopic data analysis (MS, UV, IR, and NMR). Compound 1 exhibited certain...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1670169
更新日期:2020-05-01 00:00:00
abstract::A new coumestan named bavacoumestan D (1), together with five known compounds (2-6), was isolated from EtOAc-soluble extract of seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All compounds were evaluated for in vitro inhibitory activity agai...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1563073
更新日期:2020-03-01 00:00:00
abstract::Three series of sulfonate derivatives of paeonol were synthesized and screened in vitro for their anti-oomycete activity against P. capsici, respectively. Among all the compounds, 4m displayed the best promising and pronounced anti-oomycete activity against P. capsici than zoxamide, with the EC50 values of 24.51 and 2...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2020.1718116
更新日期:2020-02-03 00:00:00
abstract::Three new alkylated benzoquinones, 2-hydroxy-5-ethoxy-3-nonyl-1,4-benzoquinone (1), 5-O-butyl-embelin (2), and 2,5-dihydroxy-6-methyl-3-pentadecyl-1,4-benzoquinone (3), together with seven known analogues (4-10), were isolated from the stems and twigs of mangrove plant, Aegiceras corniculatum. Their structural elucida...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1540604
更新日期:2020-02-01 00:00:00
abstract::We present the synthesis of enantiomerically pure (S)-α-methyl-serine methyl ester hydrochloride from 2-methyl-3-((4-(trifluoromethyl)benzyl)oxy)propanal and di-p-chlorobenzyl azodicarboxylate via asymmetrically catalyzed amination with naphthylalanine derivative catalyst. The application of the organocatalyst of D-3-...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1634058
更新日期:2020-01-01 00:00:00
abstract::Phytochemical investigation on the leaves of Rabdosia serra led to the isolation of two new abietane diterpenoids, raserranes A (1) and B (2), and four known phenylpropanoids (3-6). Their structures were determined by spectroscopic data. Compound 1 represented the rare examples of abietane diterpenoids featuring a 16-...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1539081
更新日期:2020-01-01 00:00:00
abstract::Two new isobenzofuranone derivatives, polyphthaliside A (1) and polyphthaliside B (2), and a new isocoumarin derivative, polyisocoumarin (3), were isolated from Polygonum cuspidatum. Their structures were elucidated by detailed spectroscopic analysis and chemical methods. The cytotoxicity activity and PTP1B inhibitory...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1646730
更新日期:2020-01-01 00:00:00
abstract::Three new eremophilane-type sesquiterpenoids, alashanoids K-M (1-3), and one known analogue (4) were isolated from the peeled stems of Syringa pinnatifolia. All the compounds were isolated from the genus Syringa for the first time. Structures of these compounds were established using 1D and 2D NMR and MS data. The abs...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2019.1694516
更新日期:2019-12-01 00:00:00
abstract::Two new abietane diterpenoid glucosides, talienosides A and B (1 and 2), along with four known compounds (3 - 6), were isolated from the ethyl acetate soluble portion of 70% acetone extract of the underground parts of Isodon taliensis. Their structures were elucidated based on the analyses of extensive spectroscopic d...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1518321
更新日期:2019-12-01 00:00:00
abstract::Two new sesquiterpene pyridine alkaloids, Chinese bittersweet alkaloid A (1) and Chinese bittersweet alkaloid B (2), together with five known compounds 3β- hydroxyolean-9(11),12-diene, β-sitosterol, 1β,2β,6α,15β-tetraacetoxy-8β,9α- dibenzoyloxy-β-dihydroagarofuran, angulatin A and angulatin J, were isolated from the r...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1492563
更新日期:2019-11-01 00:00:00
abstract::Two rarely phenolic acid-substituted alloses (1, 2) and one new glucoside (3), as well as nine known compounds (4-12) were isolated from rhizomes of Cibotium barometz (L.) J. Sm. Structures of 1-3 were established by extensively spectroscopic analyses (NMR, MS, etc.) and acid hydrolysis. All compounds were evaluated f...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1563076
更新日期:2019-10-01 00:00:00
abstract::A phytochemical study on the seeds of Cassia obtusifolia was carried out, which finally led to obtain two naphthalenes (1 and 2), two naphthopyrans (3 and 4) and twelve anthraquinones (5-16). The structures of all compounds were established mainly by NMR and MS experiments as well as the necessary chemical evidence. A...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1478816
更新日期:2019-10-01 00:00:00
abstract::Four new C19-diterpenoid alkaloids, hemaconitines A-D (1-4), were isolated from the roots of Aconitum hemsleyanum var. circinatum. Their structures were elucidated as 19R-hydroxyl-secoyunnaconitine (1), (3R)-hydroxyl-liwaconitine (2), 14-anisoyl-leucanthumsine E (3), and 19R -acetonyl-8-O-methyltalatisamine (4) by ext...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1500555
更新日期:2019-09-01 00:00:00
abstract::The loss of glutamate transporter-1 (GLT-1) is associated with temporal lobe epilepsy (TLE). A recent study reported that Hsp90β interacted with GLT-1 and recruited it to 20S proteasome for degradation. Therefore, inhibiting Hsp90β may be a new strategy for treating epilepsy. So far, no studies have shown whether the ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1530989
更新日期:2019-09-01 00:00:00
abstract::Andrographolide, a major bioactive compound isolated from Andrographis paniculata (Burm. F.) Nees, was evaluated for its effects on the hOAT1 membrane transporter. Substrate determination and inhibition of hOAT1-mediated uptake transport assay was carried out using recombinant CHO-hOAT1 cells. The results showed that ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1520704
更新日期:2019-08-01 00:00:00
abstract::Three new triterpenoid saponins, julibrosides A5-A7 (1-3), together with five known saponins (4-8), were isolated from the stem bark of Albizia julibrissin. Their structures were elucidated on the basis of extensive spectroscopic data analysis of MS, 1D and 2D NMR, and chemical methods. Compounds 7 and 8 were isolated...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1473385
更新日期:2019-06-01 00:00:00
abstract::Two new lignans named neourticol A (1) and neourticol B (2), together with seven known compounds (3-9), were isolated from Urticae Fissae Herba, a folk medicine for rheumatism arthritis in China. The active evaluation results showed that 1 and 2 possessed the potent anti-complement and anti-inflammatory activities. ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1457652
更新日期:2019-06-01 00:00:00
abstract::Pfaffia paniculata is a commercialized dietary supplement used as the substitute for the Asian ginseng in Brazil. We conducted the systematic isolation of the EtOAc fraction with anti-inflammatory effect and two new triterpenoids, along with 26 known compounds were characterized by means of MS and NMR analysis. Intere...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1446949
更新日期:2019-05-01 00:00:00
abstract::Two new halogenated nonterpenoids C15-acetogenins, nangallenes A-B (1-2), together with two known halogenated compounds itomanallene A (3) and 2,10-dibromo-3-chloro-α-chamigrene (4), were isolated and identified from the organic extract of the marine red alga Laurencia nangii Masuda collected from the coastal waters i...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2017.1417265
更新日期:2019-03-01 00:00:00
abstract::Two new diterpenoid glycosides, fructusnoids D (1) and E (2), and two new monoterpenoid glycosides (3, 4), together with three known diterpenoid glycosides (5-7) and three known monoterpenoid glycosides (8-10), were isolated from the fruits of Xanthium chinense. Their structures were elucidated by spectrometric analys...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1526788
更新日期:2019-03-01 00:00:00
abstract::Samoamide A is a cyclic octapeptide rich in proline and phenylalanine residues isolated from an American Samoa marine cyanobacterium, which exhibits potent activity against H460 human non-small-cell lung cancer cells (IC50 of 1.1 μM). The first total synthesis of samoamide A was achieved by employing a strategy of a s...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1450391
更新日期:2019-02-01 00:00:00
abstract::A new diterpenoid, 17-methyl-8, 13-labdadien-15, 16-olid-19-oic acid methyl ester (1), along with two known compounds 2 and 3, were isolated from the leaves of Platycladus orientalis (L.) Franco. The structures were confirmed based on the analysis of HR-MS, 1D-NMR, and 2D-NMR spectra and the configuration of 1 was con...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2017.1373102
更新日期:2018-11-01 00:00:00
abstract::A series of novel tetrandrine (Tet) derivatives were synthesized through Suzuki -Miyaura reaction and evaluated for their cytotoxicity against human non-small cell lung carcinoma (NSCLC) A549 cells. Interestingly, most of derivatives showed similar cytotoxicity to Tet against NSCLC A549 cells, and particularly, compou...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2018.1478817
更新日期:2018-11-01 00:00:00
abstract::Two new cycloartanes, named dolichandrone A (1) and dolichandrone B (2), as well as two new iridoids, named [6-O-[(E)-4-methoxycinnamoyl]-1β-hydroxy-dihydrocatalpolgenin (3) and 6-O-[(E)-4-methoxycinnamoyl]-1α-hydroxy-dihydrocatalpolgenin (4), together with four known iridoids (5-8), were isolated from the leaves and ...
journal_title:Journal of Asian natural products research
pub_type: 杂志文章
doi:10.1080/10286020.2017.1406927
更新日期:2018-09-01 00:00:00