A new diimide derivative from the co-culture broth of two mangrove fungi (strain no. E33 and K38).

abstract：:Chrysoeriol (1) was isolated as the main constituent from the methanol extract of the dried leaves of Eurya ciliata Merr. To investigate the bioactivities of 1 on bone metabolism, its effects on the function of osteoblastic MC3T3-E1 cells were studied. Compound 1 significantly increased the growth of MC3T3-E1 cells an...

journal_title：Journal of Asian natural products research

authors： Tai BH,Cuong NM,Huong TT,Choi EM,Kim JA,Kim YH

更新日期：2009-09-01 00:00:00

abstract：:Four new minor taxanes (1-4) have been isolated from Ts-19 cell cultures of Taxus chinensis together with five known taxanes (5-9) by silica gel chromatography combined with semi-preparative HPLC chromatography. On the basis of the analyses of the chemical and spectroscopic (IR, MS, 1D, and 2D NMR) data, the structure...

journal_title：Journal of Asian natural products research

authors： Xie D,Jia HT,Zhang Y,Zou JH,Yin DL,Chen XG,Yan YN,Dai JG

更新日期：2009-06-01 00:00:00

abstract：:Gamboge is a dry resin secreted from Garcinia hanburryi, and gambogenic acid (GNA) is one of the main active compounds of gamboge. We have previously demonstrated the anticancer activity of GNA in A549 cells and pointed out its potential effects in anticancer therapies. Previous studies reported that GNA induced apopt...

journal_title：Journal of Asian natural products research

authors： Cheng H,Su JJ,Peng JY,Wang M,Wang XC,Yan FG,Wang XS,Li QL

更新日期：2011-10-01 00:00:00

abstract：:Andrographolide, a major bioactive compound isolated from Andrographis paniculata (Burm. F.) Nees, was evaluated for its effects on the hOAT1 membrane transporter. Substrate determination and inhibition of hOAT1-mediated uptake transport assay was carried out using recombinant CHO-hOAT1 cells. The results showed that ...

journal_title：Journal of Asian natural products research

authors： Chong YM,Kaur G,Tan ML

更新日期：2019-08-01 00:00:00

abstract：:Verticilliside (1), a new flavone C-glucoside, has been isolated from the ethyl acetate soluble fraction of Enicostemma verticillatum and its structure is assigned on the basis of the spectroscopic data. 5,7,4'-Trihydroxyflavone 8-C-beta-D-glucopyranoside (2) and isoorientin 3'-O-methyl ether (3) have also been isolat...

journal_title：Journal of Asian natural products research

authors： Jahan E,Perveen S,Malik A

更新日期：2009-01-01 00:00:00

abstract：:Pseudolaric acid-B (PLAB), a diterpene acid, was isolated from the root and trunk barks of Pseudolarix kaempferi. It showed antifungal and anti-fertility effects as well as cytotoxic activities in previous studies. The present study investigates cytotoxic activity on cultured human cancer cells, inhibition on the grow...

journal_title：Journal of Asian natural products research

authors： Liu B,Chen H,Lei ZY,Yu PF,Xiong B

更新日期：2006-04-01 00:00:00

abstract：:One kinds of glycolipid (SBI) have been isolated from the marine brown alga Sargassum hemiphyllum (Turn.) Ag. The structures of SBI have been determined as the sodium salt of 1-0-acyl-3-0-(6'-sulfo-alpha-D-quinovopyrannosyl) glycerol (acyl: tetradecanoyl, pentadecanoyl, 11-hexadecenoyl, hexadecanoyl, 10,13-octadecadie...

journal_title：Journal of Asian natural products research

authors： Cui Z,Li YS,Liu HB,Yuan D,Lu BR

更新日期：2001-01-01 00:00:00

abstract：:We present the synthesis of enantiomerically pure (S)-α-methyl-serine methyl ester hydrochloride from 2-methyl-3-((4-(trifluoromethyl)benzyl)oxy)propanal and di-p-chlorobenzyl azodicarboxylate via asymmetrically catalyzed amination with naphthylalanine derivative catalyst. The application of the organocatalyst of D-3-...

journal_title：Journal of Asian natural products research

authors： Xiao Q,Tang YF,Xie P

更新日期：2020-01-01 00:00:00

abstract：:Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extr...

journal_title：Journal of Asian natural products research

authors： Su SS,Tian L,Chen G,Li ZQ,Xu WF,Pei YH

更新日期：2013-01-01 00:00:00

abstract：:Samoamide A is a cyclic octapeptide rich in proline and phenylalanine residues isolated from an American Samoa marine cyanobacterium, which exhibits potent activity against H460 human non-small-cell lung cancer cells (IC50 of 1.1 μM). The first total synthesis of samoamide A was achieved by employing a strategy of a s...

journal_title：Journal of Asian natural products research

authors： Chang Q,Li YL,Zhao X

更新日期：2019-02-01 00:00:00

abstract：:The Amaranthaceae plant, Pfaffia glomerata, which is so-called as Brazil ginseng, is widely distributed in South American countries. Three new noroleanane-type triterpenes and four known oleanane-type triterpenes were isolated from the roots of P. glomerata. Their structures were determined by spectroscopic methods in...

journal_title：Journal of Asian natural products research

authors： Han YZ,Zhou Y,Zhang ZT,Niu SY,Liu XH,Jia XY

更新日期：2018-05-01 00:00:00

abstract：:A new triterpenoid saponin named clematichinenoside AR(2), along with the six known compounds, was isolated and characterized from Clematis chinensis Osbeck (Ranunculaceae), a commonly used traditional Chinese medicine with anti-inflammatory and anti-rheumatoid activities. The structure of the new saponin was elucidat...

journal_title：Journal of Asian natural products research

authors： Liu LF,Ma XL,Wang YX,Li FW,Li YM,Wan ZQ,Tang QL

更新日期：2009-01-01 00:00:00

abstract：:Thiazinogeldanamycin (2) was identified from Streptomyces hygroscopicus 17997 at the late stage of the fermentation. The pH was firstly proposed as an important factor in the biosynthesis of it. It was verified that 2 was produced by direct chemical reactions between geldanamycin (1, GDM) and cysteine or aminoethaneth...

journal_title：Journal of Asian natural products research

authors： Liu YF,Zhong JJ,Lin L,Liu JJ,Wang YG,He WQ,Yang ZY

更新日期：2016-08-01 00:00:00

abstract：:Three new eremophilane-type sesquiterpenoids, alashanoids K-M (1-3), and one known analogue (4) were isolated from the peeled stems of Syringa pinnatifolia. All the compounds were isolated from the genus Syringa for the first time. Structures of these compounds were established using 1D and 2D NMR and MS data. The abs...

journal_title：Journal of Asian natural products research

authors： Peng B,Zhang RF,Du BZ,Jiao SG,Zhou XC,Gao XL,Chen SY,Tu PF,Chai XY

更新日期：2019-12-01 00:00:00

abstract：:Four nitrogen-containing derivatives of ginkgolide B were synthesized to improve the physical-chemical properties and bioavailability of ginkgolide B. The reaction was accomplished with the nitrogen atom as neighboring group participating in the replacement reaction. All of the four compounds were proved to have excel...

journal_title：Journal of Asian natural products research

authors： Guo CJ,Ren Y,Qin YL,Zhang Q

更新日期：2008-09-01 00:00:00

abstract：:A new meroterpenoid, tomentodione E (1), along with four known ones (2-5) were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated based on extensive spectroscopic data as well as computational methods. Compound 1 represents the first example of meroterpenoid possessing a sec-pentyl syn...

journal_title：Journal of Asian natural products research

authors： Liu J,Song JG,Su JC,Huang XJ,Ye WC,Wang Y

更新日期：2018-01-01 00:00:00

abstract：:Two new lignan glycosides forsythiayanoside A (1) and forsythiayanoside B (2), one new stereoisomer of lignan glycoside (+)-8-hydroxyepipinoresinol-4-O-β-D-glucopyranoside (3), together with seven known compounds (4-10), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. Compounds 4 and 10 were isolate...

journal_title：Journal of Asian natural products research

authors： Yan XJ,Peng Y,Liu ZX,Wen J,Liu QB,Li LZ,Song SJ

更新日期：2014-01-01 00:00:00

abstract：:A new minor sesquiterpene lactone glucoside, ixerin ZA (1), together with 16 known compounds, were isolated from the whole plants of Ixeris sonchifolia (Bge) Hance. The structure of 1 was elucidated as 1(10),3,11(13)-guaiatriene-12,6-olide-2-one-3-O-[6'-(p-metheoxyphenylacetyl)]-beta-glucopyranoside on the basis of sp...

journal_title：Journal of Asian natural products research

authors： He WF,Xu BB,Pan JC,Lu JC,Song SJ,Xu SX

更新日期：2006-09-01 00:00:00

abstract：:Two new homoisoflavonoids, ( ± )-5,7-dihydroxy-8-methyl-3-(2',4'-dihydroxybenzyl) chroman-4-one (1) and ( ± )-5,7-dihydroxy-6,8-dimethyl-3-(2',4'-dihydroxybenzyl) chroman-4-one (2), along with two known homoisoflavonoids, 5,7-dihydroxy-6-methyl-3-(2',4'-dihydroxybenzyl)chroman-4-one (3) and disporopsin (4), were isola...

journal_title：Journal of Asian natural products research

authors： Li LM,Yuan QP,Chen G

更新日期：2014-01-01 00:00:00

abstract：:A total of 15 novel-substituted 3-(benzylsulfanyl)-1H-1,2,4-triazol-5-ylamine and 10 novel-substituted 3-benzylmercapto-1,2,4-triazol derivatives were synthesized based on the natural product phenazine-1-carboxylic acid (PCA). Their structures were confirmed by 1H-NMR, 13C-NMR, HRMS, and X-ray. Most substituted 3-benz...

journal_title：Journal of Asian natural products research

authors： Li XJ,Zhang W,Zhao CN,Wu QL,Li JK,Xu ZH

更新日期：2020-05-07 00:00:00

abstract：:A series of piplartine derivatives were synthesized via Baylis-Hillman reaction and evaluated for anticancer and antibacterial activities. The cytotoxicity of these compounds was examined in two different human tumor cell lines, IMR-32 and HeLa. The antibacterial activity was examined in Staphylococcus aureus and Pseu...

journal_title：Journal of Asian natural products research

authors： Kumar JU,Shankaraiah G,Kumar RS,Pitke VV,Rao GT,Poornima B,Babu KS,Sreedhar AS

更新日期：2013-01-01 00:00:00

abstract：:Chemical examination of the methanolic extract from the stem bark of Daphne feddei led to the isolation of three new dicoumarin glucosides (1-3), and eight known coumarins, dicoumarins and dicoumarin glucosides. Their structures were elucidated by extensive analysis of spectral data and comparison with the literature ...

journal_title：Journal of Asian natural products research

authors： Liang S,Feng Y,Tian JM,Lu M,Xiong Z,Zhang WD

更新日期：2011-12-01 00:00:00

abstract：:Podophyllotoxin and its synthetic derivatives are valuable medicinal agents that have antitumor, insecticidal, and antifungal properties. We previously synthesized a deoxypodophyllotoxin derivative with an opened D-ring (DPD) exhibiting potent insecticidal activity. This article was firstly performed to identify the c...

journal_title：Journal of Asian natural products research

authors： Chen C,Wang CC,Wang Z,Geng WY,Xu H,Song XM,Luo DQ

更新日期：2016-05-01 00:00:00

abstract：:Three new ursane-type triterpenoids, 2α,3β-dihydroxy-11α,12α-epoxy-urs-28,13β-olide (1), 2α,3β,24-trihydroxy-11α,12α-epoxy-urs-28,13β-olide (2), and 2α,3α,24-trihydroxy-11,20(30)-dien-urs-28,13β-olide (6), together with six known ursane-type triterpenoids (3-5, 7-9), were isolated from the EtOAc extract of the aerial ...

journal_title：Journal of Asian natural products research

authors： Jiao K,Li HY,Zhang P,Pi HF,Ruan HL,Wu JZ

更新日期：2013-09-01 00:00:00

abstract：:A seco-apotirucallane-type triterpenoid, namely angustifolianin (1), along with three dammarane-type triterpenoids, (20S, 24S)-epoxy-dammarane-3β,25-diol (2), 3-epi-cabraleahydroxylactone (3), and cabralealactone (4), were isolated from the stem bark of Aglaia angustifolia Miq. The Chemical structure of the new compou...

journal_title：Journal of Asian natural products research

authors： Hutagaol RP,Harneti D,Safari A,Hidayat AT,Supratman U,Awang K,Shiono Y

更新日期：2020-06-13 00:00:00

abstract：:A new pyranoxanthone, venuloxanthone (1), was isolated from the stem bark of Calophyllum venulosum, together with three other xanthones, tovopyrifolin C (2), ananixanthone (3) and caloxanthone I (4), along with two common triterpenes, friedelin (5) and lupeol (6). The structures of these compounds were identified usin...

journal_title：Journal of Asian natural products research

authors： Bin Ismail AA,Ee GC,Bin Daud S,Teh SS,Hashim NM,Awang K

更新日期：2015-01-01 00:00:00

abstract：:Investigation of the constituents from the stem barks of Garcinia multiflora has yielded two new compounds, multiflorabiphenyl A (1) and 24-p-E-coumaroyl-tetracosanyl (E)-ferulate (2), along with 10 known compounds, friedelin (3), friedelan-3β-ol (4), α,β-amyrin (5), rheediachromenoxanthone (6), 1,7-dihydroxyxanthone ...

journal_title：Journal of Asian natural products research

authors： Jing WY,Jiang C,Ji F,Hua HM,Li ZL

更新日期：2013-11-01 00:00:00

abstract：:Seven new C14-polyacetylene glucosides codonopilodiynosides A-G (1-7) were isolated from an aqueous extract of the Codonopsis pilosula roots. Their structures were determined by spectroscopic and chemical methods as (-)-(5S,6E,12E)-tetradeca-6,12-dien-8,10-diyn-1,5,14-triol 5-O-β-D-glucopyranoside (1), (-)-(5S,6E,12E)...

journal_title：Journal of Asian natural products research

authors： Jiang YP,Liu YF,Guo QL,Jiang ZB,Xu CB,Zhu CG,Yang YC,Lin S,Shi JG

更新日期：2015-01-01 00:00:00

abstract：:Pharmacologically motivated natural product investigations have yielded a large variety of structurally unique lead compounds with interesting biomedical properties, but the natural roles of these molecules often remain unknown. In the present investigation, a series of benzyl substituted-flavone derivatives have been...

journal_title：Journal of Asian natural products research

authors： Kumar GS,Tiwari AK,Rao VR,Prasad KR,Ali AZ,Babu KS

更新日期：2010-11-01 00:00:00

abstract：:From the EtOH extract of the flowers of Camellia nitidissima Chi, a new acylated flavonoid glycoside, quercetin 7-O-(6"-O-E-caffeoyl)-β-D-glucopyranoside (1), has been isolated, together with three known flavonoids: quercetin (2), quercetin 3-O-β-D-glucopyranoside (3), and quercetin 7-O-β-D-glucopyranoside (4). Their ...

journal_title：Journal of Asian natural products research

authors： Peng X,Yu DY,Feng BM,Wang YQ,Shi LY

更新日期：2012-01-01 00:00:00