Total synthesis and cyclization strategy of samoamide A, a cytotoxic cyclic octapeptide rich in proline and phenlalanine isolated from marine cyanobacterium.

abstract：:Three new eremophilane-type sesquiterpenoids, alashanoids K-M (1-3), and one known analogue (4) were isolated from the peeled stems of Syringa pinnatifolia. All the compounds were isolated from the genus Syringa for the first time. Structures of these compounds were established using 1D and 2D NMR and MS data. The abs...

journal_title：Journal of Asian natural products research

authors： Peng B,Zhang RF,Du BZ,Jiao SG,Zhou XC,Gao XL,Chen SY,Tu PF,Chai XY

更新日期：2019-12-01 00:00:00

abstract：:Two new sesquiterpene derivatives, (+)-8β-hydroxy-longicamphenylone (1) and 11β-hydroxy-13-isopropyl-dihydrodehydrocostus lactone (2), were isolated from Chinese eaglewood. Their structures were elucidated on the basis of spectroscopic analyses including HR-ESI-MS, (1)H and (13)C NMR, DEPT, (1)H-(1)H COSY, HSQC, HMBC,...

journal_title：Journal of Asian natural products research

authors： Yang L,Qiao LR,Zhang JJ,Dai JG,Guo SX

更新日期：2012-01-01 00:00:00

abstract：:Phytochemical analysis of the MeOH extract of the fruiting bodies of Stropharia aeruginosa resulted in the isolation of three lanostane triterpenoids, aeruginosols A, B and C. The structures of the new compounds were determined by spectroscopic analysis. The biological activities of aeruginosols A, B and C were examin...

journal_title：Journal of Asian natural products research

authors： Shiono Y,Sugawara H,Nazarova M,Murayama T,Takahashi K,Ikeda M

更新日期：2007-09-01 00:00:00

abstract：:Marine sponges are currently one of the richest sources of anticancer active compounds found in the marine ecosystems. More than 5300 different known metabolites are from sponges and their associated microorganisms. To survive in the complicated marine environment, most of the sponge species have evolved chemical mean...

journal_title：Journal of Asian natural products research

authors： Ye J,Zhou F,Al-Kareef AM,Wang H

更新日期：2015-01-01 00:00:00

abstract：:A new triterpenoid saponin named clematichinenoside AR(2), along with the six known compounds, was isolated and characterized from Clematis chinensis Osbeck (Ranunculaceae), a commonly used traditional Chinese medicine with anti-inflammatory and anti-rheumatoid activities. The structure of the new saponin was elucidat...

journal_title：Journal of Asian natural products research

authors： Liu LF,Ma XL,Wang YX,Li FW,Li YM,Wan ZQ,Tang QL

更新日期：2009-01-01 00:00:00

abstract：:Two new selaginellin derivatives, selaginellins K (1) and L (2), were isolated from Selaginella tamariscina (Beauv.) Spring and characterized as 2-formyl-4,4'-dihydroxy-3-[(4-hydroxyphenyl)ethynyl]biphene and 4,4'-dihydroxy-2-methyl-3-[(4-hydroxyphenyl)ethynyl]biphene on the basis of their spectroscopic data including...

journal_title：Journal of Asian natural products research

authors： Xu KP,Zou H,Li FS,Xiang HL,Zou ZX,Long HP,Li J,Luo YJ,Li YJ,Tan GS

更新日期：2011-04-01 00:00:00

abstract：:Two new lanostanoid triterpenes, 23S-hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic acid (1), and 12beta-acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20E-diene-26-oic acid (16), together with 17 known compounds, were isolated from the fruit bodies of Ganoderma lucidum. Their structures were established by ...

journal_title：Journal of Asian natural products research

authors： Guan SH,Xia JM,Yang M,Wang XM,Liu X,Guo DA

更新日期：2008-07-01 00:00:00

abstract：:Irritant and cytotoxic potentiality of six coumarins, isolated for the first time from the roots of Angelica glauca identified as 5,6,7-trimethoxycoumarin, 6-methoxy-7,8-methylenedioxycoumarin, bergapten, decursinol angelate, decursin, and nodakenetin, were investigated. The irritant potential was explored by open mou...

journal_title：Journal of Asian natural products research

authors： Saeed MA,Sabir AW

更新日期：2008-01-01 00:00:00

abstract：:A new 3,4-seco-labdane diterpenoid, 3,4-seco-12R,13S-dihydroxy-4(18),8(17),14(15)-labdatrien-3-oic acid (1), was isolated from the leaves of Callicarpa nudiflora. The structure of 1 was elucidated by 1D NMR, 2D NMR and HRESIMS data, and confirmed by single-crystal X-ray diffraction analysis. 3,4-seco-12R,13S-Dihydroxy...

journal_title：Journal of Asian natural products research

authors： Zhang L,Liu MS,Huang J,Li GY,Zhang C,Dong L,Zhang K,Wang JH

更新日期：2014-01-01 00:00:00

abstract：:Two new dammarane-type triterpene saponins were isolated from the red American ginseng. The new saponins were named as pseudoginsenoside G(1) and pseudoginsenoside G(2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 3-O-[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl]-dammar-...

journal_title：Journal of Asian natural products research

authors： Liu JP,Lu D,Li PY

更新日期：2011-03-01 00:00:00

abstract：:Four new lignan glycosides (1-4), named procumbenosides I, K, L, and M, together with cleistanthin B (5) reported for the first time in the genus Justicia, and 5 other known arylnaphthalene lignan glycosides (6-10) were isolated from the whole plant of Justicia procumbens. The structures of the new compounds were eluc...

journal_title：Journal of Asian natural products research

authors： Jin H,Yang S,Dong JX

更新日期：2017-01-01 00:00:00

abstract：:Two new phthalates bis(2-ethylundecyl)phthalate and bis(2-ethyltridecyl)phthalate have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei along with one known compound β-amyrin. The structures of the two new compounds and β-amyrin were assigned on the basis of their ¹H and ¹³C NMR s...

journal_title：Journal of Asian natural products research

authors： Hussain J,Rehman NU,Hussain H,Ali L,Al-Harrasi A

更新日期：2012-01-01 00:00:00

abstract：:Two new diterpenes and ent-15alpha-hydroxykaur-16-en-19-oic acid 11,12-acetonide (3), together with 23 known compounds were isolated from the dried aerial parts of Nouelia insignis Franch. The structures of new compounds were determined to be ent-14beta,15alpha-dihydroxykaur-16-en-19-oic acid (1), ent-14beta-hydroxy-1...

journal_title：Journal of Asian natural products research

authors： Hu XY,Luo YG,Chen XZ,Zhou L,Zhang GL

更新日期：2008-01-01 00:00:00

abstract：:Vernonia travancorica Hook. f. is a taxon, endemic to the evergreen forests of Western Ghats (above 1000 m), India. From the aqueous EtOH extract of the air-dried corymbose inflorescence a novel secondary metabolite, 3-O-beta-[beta-(6'''-acetyl)-D-glucopyranosyl(1-->2)]-D-glucopyranosyl kaempferol (1), has been isolat...

journal_title：Journal of Asian natural products research

authors： Seetharaman TR,Petrus AJ

更新日期：2004-12-01 00:00:00

abstract：:A bioassay-guided phytochemical fractionation of the methanol extract of the Morus alba root barks led to the isolation of two chalcone-derived Diels-Alder adducts (1 and 2). Their structures were elucidated as kuwanon J 2,4,10″-trimethyl ether (1) and kuwanon R (2) by means of spectroscopic methods. Both compounds st...

journal_title：Journal of Asian natural products research

authors： Phung TX,Tran TH,Dan TT,Chau VM,Hoang TH,Nguyen TD

更新日期：2012-01-01 00:00:00

abstract：:A new natural compound, dehydrophyllodulcin (1) was isolated from the tubers of Scirpus yagara, together with 11 known compounds. Among them, compounds 2, 5-8, and 10-12 were isolated from this plant for the first time. (1)H NMR, (13)C NMR, and 2D NMR data of compound 1 are first reported in this article, though it wa...

journal_title：Journal of Asian natural products research

authors： Dong SH,Zhang JF,Tang YM,Li J,Xiang YR,Liang QL

更新日期：2016-08-01 00:00:00

abstract：:The protective effect of rhein lysinate (RHL) on Alzheimer's disease (AD) was explored in senescence-accelerated mouse prone-8 (SAMP8) mice. SAMP8 mice without treatment were used as the AD-positive control, and senescence-accelerated-resistant mice were used as the AD-negative control. In this study, 4-month-old male...

journal_title：Journal of Asian natural products research

authors： Liu J,Hu G,Xu R,Qiao Y,Wu HP,Ding X,Duan P,Tu P,Lin YJ

更新日期：2013-07-01 00:00:00

abstract：:One pair of new amides enantiomers (1a and 1b) and two known amides were isolated from the rhizomes of Polygonum cuspidatum. Their structures were established using UV, IR, HRESIMS, and NMR data. Notably, compound 1 possesses unique C-C connection between feruloyltyramine and resveratrol. Their absolute configurations...

journal_title：Journal of Asian natural products research

authors： Zhang X,Liu F,Feng ZM,Jiang JS,Yang YN,Zhang PC

更新日期：2021-01-18 00:00:00

abstract：:Tripterygium wilfordii Hook. f. is the traditional medicinal plants in China. Triptolide, wilforgine, and wilforine are the bioactive compounds in T. wilfordii. In this study, the contents of three metabolites and transcription levels of 21 genes involved in three metabolites biosynthesis in T. wilfordii were examined...

journal_title：Journal of Asian natural products research

authors： Zhang J,Huo YB,Liu Y,Feng JT,Ma ZQ,Zhu CS,Zhang X

更新日期：2017-08-01 00:00:00

abstract：:Epoxyeicosatrienoic acids (EETs) and their regulating enzyme soluble epoxide hydrolase (sEH) have been associated with ischemic stroke. Salvianolic acid A (SAA) is proved to display potent cerebroprotection. However, little information is available about the link between them. This study aimed to investigate whether S...

journal_title：Journal of Asian natural products research

authors： Wang SB,Pang XB,Zhao Y,Wang YH,Zhang L,Yang XY,Fang LH,Du GH

更新日期：2012-01-01 00:00:00

abstract：:A new naphthalene derivative, 1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester (1), and a new alkaloid, ( +/- )-1-phenyl-2-imido-1-propanol (2), together with the four known compounds, ephedrine, pseudoephedrine, N-methylephedrine, and 6-methoxykynurenic acid, have been isolated from the stems of ...

journal_title：Journal of Asian natural products research

authors： Zhao W,Deng AJ,Du GH,Zhang JL,Li ZH,Qin HL

更新日期：2009-01-01 00:00:00

abstract：:Two new homoisoflavonoids, ( ± )-5,7-dihydroxy-8-methyl-3-(2',4'-dihydroxybenzyl) chroman-4-one (1) and ( ± )-5,7-dihydroxy-6,8-dimethyl-3-(2',4'-dihydroxybenzyl) chroman-4-one (2), along with two known homoisoflavonoids, 5,7-dihydroxy-6-methyl-3-(2',4'-dihydroxybenzyl)chroman-4-one (3) and disporopsin (4), were isola...

journal_title：Journal of Asian natural products research

authors： Li LM,Yuan QP,Chen G

更新日期：2014-01-01 00:00:00

abstract：:A new coumarin glucoside, 8-hydroxy-5-O-beta-D-glucosylpsoralen, along with 17 known coumarins and one steroid, was isolated from the roots of Heracleum rapula Franch. Four coumarin glucosides, including the new one, were obtained from the water-soluble fraction. The other coumarins isolated from the ethyl acetate-fra...

journal_title：Journal of Asian natural products research

authors： Niu XM,Li SH,Jiang B,Zhao QS,Sun HD

更新日期：2002-03-01 00:00:00

abstract：:Methyl tortuoate D (1), together with five other known related bis-cembranoids, was isolated from Hainan soft coral Sarcophyton tortuosum. The structure of methyl tortuoate D (1a), firstly isolated and reported by Li et al. from the title organism, was corrected as 1 by an extensive analysis of its one-dimensional and...

journal_title：Journal of Asian natural products research

authors： Li YF,He LL,Liu HL,Liang LF,Zhang HB,Guo YW

更新日期：2013-01-01 00:00:00

abstract：:Two new polyketides, 3,11-dihydroxy-6,8-dimethyldodecanoic acid (1) and trichopyrone B (2), together with two known polyketides, sorbicillin (3) and penicillone A (4), have been isolated from the cultures broth of the fungus Penicillium decumbens. Their structures were elucidated by extensive spectroscopic analysis. A...

journal_title：Journal of Asian natural products research

authors： Lin S,Wu YZ,Chen KY,Ye J,Yang XW,Zhang WD

更新日期：2018-05-01 00:00:00

abstract：:A new benzofuran-type lignan, vitrifol A (1), was isolated from the fruits of Vitex trifolia, along with three known compounds 2-4. Their structures were elucidated mainly on the basis of 1D, 2D NMR and MS spectral data. Compound 1 was first isolated as a dimer of dihydrobenzofuran-type lignan. ...

journal_title：Journal of Asian natural products research

authors： Gu Q,Zhang XM,Zhou J,Qiu SX,Chen JJ

更新日期：2008-05-01 00:00:00

abstract：:Two new steroidal saponins were isolated from the fruits of Tribulus terrestris L. Their structures were elucidated by spectroscopic and chemical analysis as (23S,24R,25R)-5alpha-spirostane-3beta,23,24-triol-3-O-{alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 4)]-beta-D-galactopyranoside} (1) and (23S...

journal_title：Journal of Asian natural products research

authors： Liu T,Lu X,Wu B,Chen G,Hua HM,Pei YH

更新日期：2010-01-01 00:00:00

abstract：:Two new C19-diterpenoid alkaloids, straconitines A (1) and B (2), were isolated from the roots of Aconitum straminiflorum. Their structures were elucidated as 14-benzoylducloudine D (1) and 6-hydroxy-14-benzoylducloudine D (2) based on spectroscopic analysis, including IR, ESI-MS, HR-ESI-MS, 1D, and 2D NMR. ...

journal_title：Journal of Asian natural products research

authors： Qi Y,Zhao DK,Zi SH,Zhang LM,Guo CX,Li GQ,Xun JJ,Shen Y

更新日期：2016-01-01 00:00:00

abstract：:A new ceramide urticamide (1), two new secolignans urticalactones I (2) and Ⅱ (3), and a new flavonoid glycoside urticaside (4), together with 15 known compounds (4-19), were isolated from the leaves of Urtica fissa, a folk medicine for rheumatism arthritis in China. The active evaluation results showed that 1, 2, 3, ...

journal_title：Journal of Asian natural products research

authors： Wang MY,Yang Y,Zhou XY,Wang SS,Duan SX,Li XB

更新日期：2018-08-01 00:00:00

abstract：:Two new C-glucosyl flavonoids 6''-O-feruloylspinosin and 6''-O-feruloyl-6'''-p-hydroxybenzoylspinosin, together with five known compounds, were isolated from the seeds of Ziziphus jujube (Rhamnaceae family). Their structures were elucidated on the basis of chemical and spectroscopic evidences. Compounds 1-7 showed mod...

journal_title：Journal of Asian natural products research

authors： Fu Q,Ma Y,Chen J,Yuan HM,Zheng YZ

更新日期：2017-05-01 00:00:00