Chemical constituents from the tubers of Scirpus yagara and their anti-inflammatory activities.

Abstract:

:A new natural compound, dehydrophyllodulcin (1) was isolated from the tubers of Scirpus yagara, together with 11 known compounds. Among them, compounds 2, 5-8, and 10-12 were isolated from this plant for the first time. (1)H NMR, (13)C NMR, and 2D NMR data of compound 1 are first reported in this article, though it was synthesized in 1996. The structures of all compounds were determined by comprehensive analyses of their spectroscopic data and compared with literature information. Moreover, the anti-inflammatory effects of compounds 1, 3, 4, 6, and 9 against inflammatory cytokines production in Lipopolysaccharide - or Pam3csk4-stimulated macrophage RAW264.7 cells were evaluated by Enzyme-linked immunosorbent assay. And these compounds significantly inhibited the tumor necrosis factor (TNF)-α, interleukin (IL)-6 productions in RAW264.7 cells, with IC50 values less than 20 μM.

journal_name

J Asian Nat Prod Res

authors

Dong SH,Zhang JF,Tang YM,Li J,Xiang YR,Liang QL

doi

10.1080/10286020.2016.1158166

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

791-7

issue

8

eissn

1028-6020

issn

1477-2213

journal_volume

18

pub_type

杂志文章
  • Two new compounds from Trifolium resupinatum var. microcephalum.

    abstract::An investigation of CH(2)Cl(2) and EtOH extracts of Trifolium resupinatum L. var. microcephalum Zoh. has led to the isolation of two new compounds characterized as 4,15-dimethyl-2-(1,2-dihydroxyethyl)-hexadecene (1) and 1-undecene-1-O-beta-2',3',4',6'-tetraacetyl glucopyranoside (2a). Their structures were established...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802278038

    authors: Sabudak T,Isik E,Oksuz S

    更新日期:2008-11-01 00:00:00

  • Two new abietane diterpenoids from the leaves of Rabdosia serra.

    abstract::Phytochemical investigation on the leaves of Rabdosia serra led to the isolation of two new abietane diterpenoids, raserranes A (1) and B (2), and four known phenylpropanoids (3-6). Their structures were determined by spectroscopic data. Compound 1 represented the rare examples of abietane diterpenoids featuring a 16-...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1539081

    authors: Liu GL,Xu W,Liu XJ,Yan XL,Chen J

    更新日期:2020-01-01 00:00:00

  • Total synthesis of 3,7-dimethyl-7-hydroxy-2-octen-1,6-olide and 3,7-dimethyl-2,6-octadien-1,6-olide.

    abstract::3,7-Dimethyl-7-hydroxy-2-octen-1,6-olide and 3,7-dimethyl-2,6-octadien-1,6-olide, the natural bioactive compounds isolated from the fruit of Litsea cubeba and the liverwort Plagiochila rutilans, were totally synthesized using easily available cis-geraniol as raw material in short, convenient, and low-cost, five-step r...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.803474

    authors: Dong HB,Yang MY,Jiang JZ,Wang MA

    更新日期:2013-01-01 00:00:00

  • (+)-Cyclopenol, a new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid from the fungus Penicillium sclerotiorum endogenous with the Chinese mangrove Bruguiera gymnorrhiza.

    abstract::One new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide C (5), viridicatin (6), 3-O-methylviridicatin (7), verrucosidin (8), ergoster...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.911290

    authors: Li J,Wang J,Jiang CS,Li G,Guo YW

    更新日期:2014-01-01 00:00:00

  • Three 11,12-seco-tanshinone derivatives from the rhizomes of Salvia miltiorrhiza.

    abstract::Three new compounds named tanshinoic acid A (1), tanshinoic acid B (2), and tanshinoic acid C (3) were isolated from the rhizomes of Salvia miltiorrhiza, together with two known compounds methyl salvianolate A (4) and methyl salvianolate C (5). Their structures were determined on the basis of spectroscopic data (UV, I...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1799988

    authors: Gu QC,Yin ZK,Feng ZM,Jiang JS,Zhang X,Zhang PC,Yang YN

    更新日期:2020-10-01 00:00:00

  • Two new compounds from the metabolites of a marine-derived actinomycete Streptomyces cavourensis YY01-17.

    abstract::Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extr...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.762764

    authors: Su SS,Tian L,Chen G,Li ZQ,Xu WF,Pei YH

    更新日期:2013-01-01 00:00:00

  • Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra.

    abstract::A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sang...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1350653

    authors: Hu X,Yu MH,Yan GR,Wang HY,Hou AJ,Lei C

    更新日期:2018-05-01 00:00:00

  • A new stilbene dimer--shegansu B from Belamcanda chinensis.

    abstract::A new dimeric stilbene, named shegansu B (1) was isolated from the ethanolic extract of the roots of Belamtantida chinensis (L.) DC., along with the known compounds isorhapontigenin, resveratol, p-hydroxybenzoic acid, iridin, tectoridin, tectorigenin and daucosterol. The structures were elucidated by means of spectros...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020008039908

    authors: Zhou LX,Lin M

    更新日期:2000-01-01 00:00:00

  • Triterpenoid saponins from the roots of Clematis chinensis Osbeck.

    abstract::A new triterpenoid saponin named clematichinenoside AR(2), along with the six known compounds, was isolated and characterized from Clematis chinensis Osbeck (Ranunculaceae), a commonly used traditional Chinese medicine with anti-inflammatory and anti-rheumatoid activities. The structure of the new saponin was elucidat...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902867268

    authors: Liu LF,Ma XL,Wang YX,Li FW,Li YM,Wan ZQ,Tang QL

    更新日期:2009-01-01 00:00:00

  • A new 2-(2-phenylethyl)chromone derivative in Chinese agarwood 'Qi-Nan' from Aquilaria sinensis.

    abstract::Phytochemical analysis of the high quality Chinese agarwood 'Qi-Nan' originating from Aquilaria sinensis (Lour.) Glig led to the isolation of a new 2-(2-phenylethyl)chromone derivative, qinanones G (1), and four known 2-(2-phenylethyl)chromones (2-5). Their structures were elucidated by spectroscopic techniques (UV, I...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.896342

    authors: Yang DL,Wang H,Guo ZK,Dong WH,Mei WL,Dai HF

    更新日期:2014-01-01 00:00:00

  • A new cycloartane glycoside from Comptosorus sibiricus rupr.

    abstract::The structure of a new cycloartane glycoside isolated from the whole herbs of Comptosorus sibiricus Rupr. has been established, by chemical and spectroscopic methods (IR, 1D and 2D NMR, HRMS, ESI-MS), as 3beta,7beta,24beta,25,30-pentahydroxycycloartane 24-O-beta-D-glucopyranoside (1). ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020310001617183

    authors: Li N,Li X,Ma ZJ,Wang JH

    更新日期:2005-04-01 00:00:00

  • Chemical constituents from the fruiting bodies of Amauroderma subresinosum.

    abstract::The chemical investigation on the fruiting bodies of Amauroderma subresinosum led to the isolation of 10 compounds including 2 new ones named amaurosubresin (1) and erythro(23,24)-5α,6α-epoxyergosta-8-ene-7-one-3β,23-diol (2). Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as MS. T...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1183650

    authors: Wang Q,Wang YG,Ma QY,Huang SZ,Kong FD,Zhou LM,Dai HF,Zhao YX

    更新日期:2016-11-01 00:00:00

  • Four new diterpenoids isolated from the Euphorbia rapulum.

    abstract::Four new diterpenoids named 1-epi-9-hydroxydepressin (1), 1-epi-8-hydroxydepressin (2), 2,13,9-trihydroxy-labda-8(17),12(E),14-triene (3) and tagalsin I (4) were isolated from Euphorbia rapulum. The structures of these compounds were elucidated by means of various spectroscopic methods. All the isolated compounds were...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1170813

    authors: Liu XX,Shang L,Huang C,Feng XS,Li W,Sha Y,Huang J,Wang JH

    更新日期:2016-09-01 00:00:00

  • New iridoids from Pedicularis artselaeri.

    abstract::Three new iridoids, named artselaenin I, II and III, were isolated from the whole plants of Pedicularis artselaeri, along with 11 known compounds, 8-epiloganic acid, 7-deoxy-8-epiloganic acid, plantarenaloside, mussaenoside, lariciresinol-4-O-beta-D-glucoside, lariciresinol-4'-O-beta-D-glucoside, alaschaniosideA, cirt...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286029808039851

    authors: Su BN,Zhai JJ,Jia ZJ

    更新日期:1998-01-01 00:00:00

  • New cycloartanes and new iridoids from Dolichandrone spathacea collected in the mangrove forest of Soc Trang province, Vietnam.

    abstract::Two new cycloartanes, named dolichandrone A (1) and dolichandrone B (2), as well as two new iridoids, named [6-O-[(E)-4-methoxycinnamoyl]-1β-hydroxy-dihydrocatalpolgenin (3) and 6-O-[(E)-4-methoxycinnamoyl]-1α-hydroxy-dihydrocatalpolgenin (4), together with four known iridoids (5-8), were isolated from the leaves and ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1406927

    authors: Nguyen VT,Do LQ,Nguyen TA,Nguyen TT,Tran VL,Ho NA,Tran VC,Tran VS,Tran TPT

    更新日期:2018-09-01 00:00:00

  • New dibenz[b, f]oxepins from Cercis chinensis Bunge.

    abstract::Three new dibenz[b,f]oxepins: 6-methoxy-7-methyl-8-hydroxydibenz[b, f]oxepin (1), 1,8-dimethoxy-6-hydroxy-7-methyldibenz[b, f]oxepin (2), and 1-hydroxy-6,8-dimethoxy-7-methyldibenz[b,f]oxepin (3), along with two known dibenz[b,f]oxepins pacharin (4) and bauhiniastatin 4 (5), were isolated from Cercis chinensis Bunge (...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020600979860

    authors: Mu LH,Li JB,Yang JZ,Zhang DM

    更新日期:2007-09-01 00:00:00

  • Thiophenes from Echinops latifolius.

    abstract::Six thiophenes were isolated and purified from ethanol extract of the roots of Echinops latifolius Tausch. Their structures were identified on the basis of spectral data. Among them, 5-(3-hydroxmethyl-3-isovaleroyloxyprop-1-ynyl)-2,2'-bithiophene (6) is a new compound, and 5-(3-hydroxy-4-isovaleroyloxybut-1-ynyl)-2,2'...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500176724

    authors: Wang Y,Li X,Meng DL,Li ZL,Zhang P,Xu J

    更新日期:2006-10-01 00:00:00

  • A new 3,4-seco-labdane diterpenoid with inhibitory activity against the production of nitric oxide from the leaves of Callicarpa nudiflora.

    abstract::A new 3,4-seco-labdane diterpenoid, 3,4-seco-12R,13S-dihydroxy-4(18),8(17),14(15)-labdatrien-3-oic acid (1), was isolated from the leaves of Callicarpa nudiflora. The structure of 1 was elucidated by 1D NMR, 2D NMR and HRESIMS data, and confirmed by single-crystal X-ray diffraction analysis. 3,4-seco-12R,13S-Dihydroxy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.841675

    authors: Zhang L,Liu MS,Huang J,Li GY,Zhang C,Dong L,Zhang K,Wang JH

    更新日期:2014-01-01 00:00:00

  • The first total synthesis of anemarchalconyn and anemarcoumarin A.

    abstract::Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1275583

    authors: Zhang JX,Li ZY,Wang YC,Ma WB,Hou M,Cao SH,Tang KH,Dong HB

    更新日期:2017-09-01 00:00:00

  • Two new meroterpenes from endophytic fungus A1 of Scyphiphora hydrophyllacea.

    abstract::Two new meroterpenes, guignardone D (1) and guignardone E (2), were isolated from endophytic fungus A1 of Scyphiphora hydrophyllacea Gaertn. F. Their structures were established based on spectroscopic methods including 1D and 2D NMR (HMQC, (1)H-(1)H COSY, HMBC, and ROESY). ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.693078

    authors: Zheng B,Zeng YB,Dai HF,Zuo WJ,Guo ZK,Yang T,Zhong HM,Mei WL

    更新日期:2012-01-01 00:00:00

  • Stemoninine-type alkaloids from the roots of Stemona sessilifolia.

    abstract::Two new stemoninine-type alkaloids, stemoninine A (1) and B (2), along with two known Stemona alkaloids, bisdehydrostemoninine (3) and bisdehydrostemoninine A (4), were isolated from the roots of Stemona sessilifolia, and their structures and relative configurations were determined on the basis of spectrometric data a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020701833511

    authors: Wang P,Liu AL,Li ZH,Du GH,Qin HL

    更新日期:2008-03-01 00:00:00

  • Synthesis of novel tetrandrine derivatives and their inhibition against NSCLC A549 cells.

    abstract::A series of novel tetrandrine (Tet) derivatives were synthesized through Suzuki -Miyaura reaction and evaluated for their cytotoxicity against human non-small cell lung carcinoma (NSCLC) A549 cells. Interestingly, most of derivatives showed similar cytotoxicity to Tet against NSCLC A549 cells, and particularly, compou...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1478817

    authors: Yang QH,Jiang CS,Jin T,Xu JF,Qu TL,Guo YW,Zhao ZB

    更新日期:2018-11-01 00:00:00

  • Synthesis and biological evaluation of novel benzyl-substituted flavones as free radical (DPPH) scavengers and α-glucosidase inhibitors.

    abstract::Pharmacologically motivated natural product investigations have yielded a large variety of structurally unique lead compounds with interesting biomedical properties, but the natural roles of these molecules often remain unknown. In the present investigation, a series of benzyl substituted-flavone derivatives have been...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.511190

    authors: Kumar GS,Tiwari AK,Rao VR,Prasad KR,Ali AZ,Babu KS

    更新日期:2010-11-01 00:00:00

  • Corydaline inhibits enterovirus 71 replication by regulating COX-2 expression.

    abstract::Enterovirus 71 (EV71) is a huge threat to the worldwide public health and there is no approved antiviral drug for EV71-induced disease therapy. Corydaline exists antiallergic and antinociceptive activities, but the anti-EV71 activity of corydaline is still not reported. In this study, corydaline could suppress the exp...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1386658

    authors: Wang HQ,Hu J,Yan HY,Wu S,Li YH

    更新日期:2017-11-01 00:00:00

  • Two new quinochalcone glycosides from the safflower yellow pigments.

    abstract::Two new quinochalcone glycosides, hydroxysafflor yellow A-4'-O-β-D-glucopyranoside (1) and 3'-hydroxyhydroxysafflor yellow A (2), were isolated from the safflower yellow pigments of Carthamus tinctorius. The structures of new compounds were elucidated by a detailed spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1846530

    authors: Zhang H,Duan CP,Luo X,Feng ZM,Yang YN,Zhang X,Jiang JS,Zhang PC

    更新日期:2020-12-01 00:00:00

  • Glycyrrhetinic acid extracted from Glycyrrhiza uralensis Fisch. induces the expression of Toll-like receptor 4 in Ana-1 murine macrophages.

    abstract::Glycyrrhetinic acid (GA) is an active component of licorice root that has long been used as a herbal medicine for the treatment of peptic ulcer, hepatitis, and pulmonary and skin diseases in Asia and Europe. In this study, we analyzed the effect of GA extracted from Glycyrrhiza uralensis Fisch. on the expression of To...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.603305

    authors: Peng LN,Li L,Qiu YF,Miao JH,Gao XQ,Zhou Y,Shi ZX,Xu YL,Shao DH,Wei JC,Ma ZY

    更新日期:2011-10-01 00:00:00

  • Coumarins from Peucedanum wulongense.

    abstract::A new angular dihydropyrancoumarin named wulongensin A, along with five known coumarins, (-)-anomalin, umbelliferone, (-)-smyrinol, 3'(S),4'(S)-disenecioyloxy-3',4'-dihydroseselin, (+)-trans-khellactone, was isolated from the root of Peucedanum wulongense. The structure of wulongensin A was established as 3'(R)-angelo...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000082034

    authors: Kong LY,Zhi F

    更新日期:2003-09-01 00:00:00

  • Three new decenynol glucosides from Artemisia scoparia (Asteraceae).

    abstract::Three new decenynol glucosides were isolated from the aerial parts of Artemisia scoparia. Their structures were determined to be 6E,8Z-decadien-4-yn-ol 1-O-β-d-glucopyranoside, 6E,8E-decadien-4-yn-ol 1-O-β-d-glucopyranoside, and 6E-decen-4-yn-ol 1-O-β-d-glucopyranoside based on extensive spectroscopic (NMR and MS) ana...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2019.1646729

    authors: Cho JY,Park KH,Hwang DY,Lee SY,Moon JH,Ju Lee Y,Park KD,Ham KS

    更新日期:2020-09-01 00:00:00

  • A new cerebroside, Asperiamide A, from the marine fungus Asperillus sp.

    abstract::A new cerebroside, asperiamide A, and adenosine were produced from a marine fungus, identified as Asperillus sp., collected in the Mei Zhou Gulf, China. Two-dimensional NMR methods, FAB-MS, were used to established the structure of the new compound. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602042000324853

    authors: Ouyang MA,Liu R,Kuo YH

    更新日期:2005-10-01 00:00:00

  • Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives.

    abstract::A novel series of acylide derivatives have been synthesized which exhibit in vitro potency against key respiratory pathogens. Modification of position 3 was accomplished by replacing different 3-O-substituted acyl groups in the macrolide core via a facile procedure. Compounds 7a-7i were eventually yielded by the conju...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020903176461

    authors: Xu P,Liu L,He W,Li Y,Liu J,Lei PS

    更新日期:2009-10-01 00:00:00